### LOVD-version 3000-30b ### Full data download ### To import, do not remove or alter this header ### ## Filter: (gene_public = CYP2D6) # charset = UTF-8 ## Genes ## Do not remove or alter this header ## ## Count = 1 "{{id}}" "{{name}}" "{{chromosome}}" "{{chrom_band}}" "{{imprinting}}" "{{refseq_genomic}}" "{{refseq_UD}}" "{{reference}}" "{{url_homepage}}" "{{url_external}}" "{{allow_download}}" "{{id_hgnc}}" "{{id_entrez}}" "{{id_omim}}" "{{show_hgmd}}" "{{show_genecards}}" "{{show_genetests}}" "{{show_orphanet}}" "{{note_index}}" "{{note_listing}}" "{{refseq}}" "{{refseq_url}}" "{{disclaimer}}" "{{disclaimer_text}}" "{{header}}" "{{header_align}}" "{{footer}}" "{{footer_align}}" "{{created_by}}" "{{created_date}}" "{{edited_by}}" "{{edited_date}}" "{{updated_by}}" "{{updated_date}}" "CYP2D6" "cytochrome P450, family 2, subfamily D, polypeptide 6" "22" "q13.1" "no" "LRG_303" "UD_132118342877" "" "https://www.LOVD.nl/CYP2D6" "Human Cytochrome P450 (CYP) Allele Nomenclature Committee \r\nPharmGKB CYP2D6 \r\nSuperCYP Cytochrome P450 database " "1" "2625" "1565" "124030" "1" "1" "1" "1" "CYP2D6 reference haplotypes. Download the current CYP2D6 DRAFT reference haplotype list (ver.2015-07-24)." "" "g" "https://databases.lovd.nl/shared/refseq/CYP2D6_codingDNA.html" "1" "" "CYP2D6 reference haplotypes. Download the current CYP2D6 DRAFT reference haplotype list (ver.2015-07-24).
\r\nNOTE: the coding DNA reference sequence represents haplotype CYP2D6*1 which differs from the reference genome sequence (build hg19). For the coding region the differences include c.408C>G, c.886T>C and c.1457C>G." "-1" "" "-1" "00001" "2013-05-03 00:00:00" "00006" "2019-08-18 09:34:46" "00000" "2025-02-07 18:57:27" ## Transcripts ## Do not remove or alter this header ## ## Count = 1 "{{id}}" "{{geneid}}" "{{name}}" "{{id_mutalyzer}}" "{{id_ncbi}}" "{{id_ensembl}}" "{{id_protein_ncbi}}" "{{id_protein_ensembl}}" "{{id_protein_uniprot}}" "{{remarks}}" "{{position_c_mrna_start}}" "{{position_c_mrna_end}}" "{{position_c_cds_end}}" "{{position_g_mrna_start}}" "{{position_g_mrna_end}}" "{{created_by}}" "{{created_date}}" "{{edited_by}}" "{{edited_date}}" "00023855" "CYP2D6" "transcript variant 1" "002" "NM_000106.4" "" "NP_000097.2" "" "" "" "-90" "1569" "1494" "42526883" "42522501" "00008" "2013-11-25 14:46:18" "" "" ## Diseases ## Do not remove or alter this header ## ## Count = 8 "{{id}}" "{{symbol}}" "{{name}}" "{{inheritance}}" "{{id_omim}}" "{{tissues}}" "{{features}}" "{{remarks}}" "{{created_by}}" "{{created_date}}" "{{edited_by}}" "{{edited_date}}" "00000" "Healthy/Control" "Healthy individual / control" "" "" "" "" "" "00000" "2012-07-26 17:29:43" "" "" "00198" "?" "unclassified / mixed" "" "" "" "" "" "00006" "2013-09-13 14:21:47" "00006" "2024-11-23 09:38:12" "00458" "DMBCYP2D6" "metabolism, drug, poor/rapid" "AR" "608902" "" "" "" "00006" "2014-07-14 13:05:48" "00006" "2021-12-10 21:51:32" "04263" "DMBur" "metabolism, drug, ultra-rapid" "" "" "" "" "" "00006" "2015-05-14 15:35:49" "00006" "2021-12-11 13:56:28" "04264" "DMBp" "metabolism, drug, poor" "" "" "" "" "" "00006" "2015-05-14 15:38:48" "00006" "2021-12-11 13:56:28" "04265" "DMBi" "metabolism, drug, intermediate" "" "" "" "" "" "00006" "2015-05-14 15:46:09" "00006" "2021-12-11 13:56:28" "04271" "DMBup" "metabolism, drug, ultra-poor" "" "" "" "" "" "00006" "2015-05-14 16:04:51" "00006" "2021-12-11 13:56:28" "04272" "DMBr" "metabolism, drug, rapid" "" "" "" "" "" "00006" "2015-05-14 16:05:54" "00006" "2021-12-11 13:56:28" ## Genes_To_Diseases ## Do not remove or alter this header ## ## Count = 2 "{{geneid}}" "{{diseaseid}}" "CYP2D6" "00458" "CYP2D6" "04264" ## Individuals ## Do not remove or alter this header ## ## Count = 449 "{{id}}" "{{fatherid}}" "{{motherid}}" "{{panelid}}" "{{panel_size}}" "{{license}}" "{{owned_by}}" "{{Individual/Reference}}" "{{Individual/Remarks}}" "{{Individual/Gender}}" "{{Individual/Consanguinity}}" "{{Individual/Origin/Geographic}}" "{{Individual/Age_of_death}}" "{{Individual/VIP}}" "{{Individual/Data_av}}" "{{Individual/Treatment}}" "{{Individual/Origin/Population}}" "{{Individual/Individual_ID}}" "00033751" "" "" "" "1" "" "00006" "{PMID:Gough 1990:1978251}" "" "-" "-" "United Kingdom (Great Britain)" "" "0" "" "" "" "" "00033753" "" "" "" "1" "" "00006" "{PMID:Steen 1995:8634695}" "" "-" "-" "" "" "0" "" "" "" "" "00033754" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033755" "" "" "" "1" "" "00006" "{PMID:Gough 1990:1978251}" "" "-" "-" "United Kingdom (Great Britain)" "" "0" "" "" "" "" "00033756" "" "" "" "1" "" "00006" "{PMID:Hanioka 1990:1978565}" "" "-" "-" "" "" "0" "" "" "" "" "00033757" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033758" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033759" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033760" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033761" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033762" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033763" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033764" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033765" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033766" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00033767" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00034026" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00034027" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00034028" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00035574" "" "" "" "1" "" "01164" "" "" "" "" "Germany" "" "0" "" "" "" "" "00035575" "" "" "" "1" "" "01164" "" "" "" "" "Germany" "" "0" "" "" "" "" "00035576" "" "" "" "1" "" "01164" "" "" "" "" "Germany" "" "0" "" "" "" "" "00035577" "" "" "" "1" "" "01164" "" "" "" "" "Germany" "" "0" "" "" "" "" "00035578" "" "" "" "1" "" "01164" "" "" "" "" "Germany" "" "0" "" "" "" "" "00035579" "" "" "" "1" "" "01164" "" "" "" "" "Germany" "" "0" "" "" "" "" "00035580" "" "" "" "1" "" "01164" "" "" "" "" "Germany" "" "0" "" "" "" "" "00035581" "" "" "" "1" "" "01164" "" "" "" "" "Germany" "" "0" "" "" "" "" "00046338" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046339" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046340" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046342" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046343" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046344" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046345" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046346" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046347" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046348" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046349" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046350" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046351" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046352" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046353" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046413" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046418" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046419" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046420" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046421" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046422" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046423" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046424" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046425" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046426" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046427" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046428" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046429" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046430" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046431" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046432" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046433" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046434" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046439" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046440" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046441" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046442" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046443" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046444" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046445" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046446" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046447" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046448" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046449" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046450" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046451" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046452" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046453" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046454" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046455" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046456" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046457" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046460" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046461" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046462" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046463" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046464" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046465" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046466" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046467" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046468" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046469" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046470" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046471" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046472" "" "" "" "1" "" "00006" "{PMID:Yamazaki 2003:15618746}" "" "" "" "Japan" "" "0" "" "" "" "" "00046473" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046474" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046475" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046476" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046477" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046478" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046479" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046480" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046481" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046482" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046483" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046484" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046485" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046486" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046487" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046488" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046489" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046490" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046491" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046492" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046493" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046494" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046495" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046496" "" "" "" "1" "" "00006" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046497" "" "" "" "1" "" "01334" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "-" "no" "Netherlands" "" "0" "" "" "" "" "00046773" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046774" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046775" "" "" "" "1" "" "00006" "{PMID:Broly 1995:8530011}" "" "-" "-" "France" "" "0" "" "" "white" "" "00046776" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046777" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046778" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046779" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046780" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00046781" "" "" "" "1" "" "00006" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "?" "no" "United States" ">00y12m" "0" "" "" "African-American" "" "00046783" "" "" "" "1" "" "00006" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "?" "?" "United States" "" "0" "" "" "" "" "00046784" "" "" "" "1" "" "00006" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "-" "-" "United States" "" "0" "" "" "" "" "00046785" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00046787" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00046796" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00046797" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00046798" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00046799" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00046800" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00046801" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00046802" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "" "" "" "0" "" "" "" "" "00052055" "" "" "" "1" "" "00006" "reference haplotype" "" "-" "-" "" "" "0" "" "" "" "" "00064644" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064645" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064646" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064647" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064648" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064649" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064650" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064651" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064652" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064658" "" "" "" "1" "" "00006" "" "reference haplotype" "-" "-" "" "" "0" "" "" "" "" "00064659" 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"" "" "0" "" "" "" "" "00074480" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074481" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074482" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074483" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074484" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074485" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074486" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074487" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074488" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074489" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074508" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074509" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074510" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074511" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074513" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074514" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074515" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074516" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00074517" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00092215" "" "" "" "1" "" "00006" "" "" "M" "no" "Netherlands" "" "0" "" "" "" "" "00092297" "" "" "" "1" "" "00006" "" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00092298" "" "" "" "1" "" "00006" "{PMID:Kramer 2009:19741566}" "reference haplotype" "" "" "" "" "0" "" "" "" "" "00092299" "" "" "" 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project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "22002" "00184149" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "22003" "00184150" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "22004" "00184151" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "22005" "00184152" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "22006" "00184153" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "22007" "00184154" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "22008" "00184155" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "23001" "00184156" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "23002" "00184157" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white/Asian" "25001" "00184158" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "25002" "00184159" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "25003" "00184160" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "25004" "00184161" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "25005" "00184162" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "25006" "00184163" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "25007" "00184164" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "25009" "00184165" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "25010" "00184166" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "25011" "00184167" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "25012" "00184168" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "25013" "00184169" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "26002" "00184170" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "26003" "00184171" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "27001" "00184172" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "27005" "00184173" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "27007" "00184174" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "27011" "00184175" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white/Asian" "27017" "00184176" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "29001" "00184177" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "30001" "00184178" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3003" "00184179" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3004" "00184180" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3005" "00184181" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3006" "00184182" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3007" "00184183" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3008" "00184184" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3009" "00184185" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3011" "00184186" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3012" "00184187" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3014" "00184188" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "Asian" "3015" "00184189" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3016" "00184190" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3017" "00184191" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white/Asian" "3018" "00184192" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3019" "00184193" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3020" "00184194" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3021" "00184195" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3022" "00184196" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3023" "00184197" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3024" "00184198" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3025" "00184199" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3027" "00184200" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3028" "00184201" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3029" "00184202" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3030" "00184203" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3031" "00184204" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3032" "00184205" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "3033" "00184206" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "3034" "00184207" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "Asian" "31001" "00184208" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white/African-American" "32002" "00184209" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "33001" "00184210" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "34001" "00184211" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "40001" "00184212" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "40002" "00184213" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "40004" "00184214" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "40005" "00184215" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "4001" "00184216" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "41001" "00184217" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "41002" "00184218" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "41003" "00184219" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "41004" "00184220" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "41005" "00184221" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "42001" "00184222" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "42002" "00184223" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "Somali" "42003" "00184224" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "43001" "00184225" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "43003" "00184226" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "5001" "00184227" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "5002" "00184228" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5003" "00184229" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "5004" "00184230" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5005" "00184231" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5006" "00184232" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5007" "00184233" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "Arabic" "5008" "00184234" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "5011" "00184235" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5012" "00184236" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5013" "00184237" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "5014" "00184238" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "5015" "00184239" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5016" "00184240" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "5017" "00184241" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5018" "00184242" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5019" "00184243" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "5020" "00184244" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6001" "00184245" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6002" "00184246" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6003" "00184247" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6004" "00184248" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6005" "00184249" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6006" "00184250" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6007" "00184251" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6008" "00184252" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6009" "00184253" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6010" "00184254" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "Asian" "6011" "00184255" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6012" "00184256" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6013" "00184257" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6014" "00184258" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6015" "00184259" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "Arabic" "6016" "00184260" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6017" "00184261" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6018" "00184262" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6019" "00184263" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6020" "00184264" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "Asian" "6021" "00184265" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "6022" "00184266" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "6023" "00184267" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "9001" "00184268" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "9002" "00184269" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "9003" "00184270" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "9004" "00184271" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "9005" "00184272" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "9006" "00184273" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "9007" "00184274" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "9008" "00184275" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "9009" "00184276" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "9010" "00184277" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "F" "no" "Netherlands" "" "0" "" "" "white" "9012" "00184278" "" "" "" "1" "" "02562" "IP3 project, submitted" "" "M" "no" "Netherlands" "" "0" "" "" "white" "9013" "00293141" "" "" "" "42" "" "03575" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "analysis 2794 individuals (India)" "" "" "India" "" "0" "" "" "" "" "00293142" "" "" "" "15" "" "03575" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "analysis 2794 individuals (India)" "" "" "India" "" "0" "" "" "" "" "00293143" "" "" "" "5" "" "03575" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "analysis 2794 individuals (India)" "" "" "India" "" "0" "" "" "" "" "00304908" "" "" "" "2" "" "03575" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "analysis 2794 individuals (India)" "" "" "India" "" "0" "" "" "" "" ## Individuals_To_Diseases ## Do not remove or alter this header ## ## Count = 368 "{{individualid}}" "{{diseaseid}}" "00033751" "00458" "00033753" "00458" "00033754" "00458" "00033755" "00458" "00033756" "00458" "00033757" "00000" "00033758" "04265" "00033759" "04265" "00033760" "04264" "00033761" "04271" "00033762" "04264" "00033763" "04264" "00033764" "04264" "00033765" "04264" "00033766" "04265" "00033767" "04265" "00034026" "04265" "00034027" "00000" "00034028" "00000" "00046338" "00000" "00046339" "00000" "00046340" "00000" "00046342" "00000" "00046343" "00000" "00046344" "00000" "00046345" "00000" "00046346" "00000" "00046347" "00000" "00046348" "00000" "00046349" "00000" "00046350" "04265" "00046351" "00000" "00046352" "00000" "00046353" "00000" "00046413" "04272" "00046418" "04264" "00046419" "04264" "00046420" "04264" "00046421" "04264" "00046422" "04264" "00046423" "04264" "00046424" "04264" "00046425" "04264" "00046426" "04264" "00046427" "04264" "00046428" "04264" "00046429" "04264" "00046430" "04264" "00046431" "04264" "00046432" "04264" "00046433" "04264" "00046434" "04271" "00046439" "04264" "00046440" "04264" "00046441" "04264" "00046442" "04265" "00046443" "04265" "00046444" "04264" "00046445" "04264" "00046446" "04264" "00046447" "04264" 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"00000" "00184239" "00000" "00184240" "00000" "00184241" "00000" "00184242" "00000" "00184243" "00000" "00184244" "00000" "00184245" "00000" "00184246" "00000" "00184247" "00000" "00184248" "00000" "00184249" "00000" "00184250" "00000" "00184251" "00000" "00184252" "00000" "00184253" "00000" "00184254" "00000" "00184255" "00000" "00184256" "00000" "00184257" "00000" "00184258" "00000" "00184259" "00000" "00184260" "00000" "00184261" "00000" "00184262" "00000" "00184263" "00000" "00184264" "00000" "00184265" "00000" "00184266" "00000" "00184267" "00000" "00184268" "00000" "00184269" "00000" "00184270" "00000" "00184271" "00000" "00184272" "00000" "00184273" "00000" "00184274" "00000" "00184275" "00000" "00184276" "00000" "00184277" "00000" "00184278" "00000" "00293141" "00198" "00293142" "00198" "00293143" "00198" "00304908" "00198" ## Phenotypes ## Do not remove or alter this header ## ## Note: Only showing Phenotype columns active for Diseases 00000, 00198, 00458, 04263, 04264, 04265, 04271, 04272 ## Count = 105 "{{id}}" "{{diseaseid}}" "{{individualid}}" "{{owned_by}}" "{{Phenotype/Inheritance}}" "{{Phenotype/Age}}" "{{Phenotype/Additional}}" "{{Phenotype/Age/Onset}}" "{{Phenotype/Age/Diagnosis}}" "{{Phenotype/Onset}}" "{{Phenotype/Protein}}" "{{Phenotype/Tumor/MSI}}" "{{Phenotype/Enzyme/CPK}}" "{{Phenotype/Heart/Myocardium}}" "{{Phenotype/Lung}}" "{{Phenotype/Diagnosis/Definite}}" "{{Phenotype/Diagnosis/Initial}}" "{{Phenotype/Diagnosis/Criteria}}" "0000027161" "00458" "00033751" "00006" "Unknown" "" "poor metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000027163" "00458" "00033753" "00006" "Familial" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000027164" "00458" "00033754" "00006" "Familial" "" "poor metaboliser (debrisoquine, sparteine)" "" "" "" "" "" "" "" "" "" "" "" "0000027165" "00458" "00033755" "00006" "Familial" "" "poor metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000027166" "00458" "00033756" "00006" "Familial" "" "poor metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000034255" "04264" "00046472" "00006" "Unknown" "" "metabolic ratio capacity dextromethorphan O-demethylation 0.016 (0.0027 for CYP2D6*1/*2)" "" "" "" "" "" "" "" "" "" "" "" "0000034297" "04264" "00046781" "00006" "Isolated (sporadic)" "" "poor metabolizer phenotype at 2w to 4m, MR (DM/DX) 0.8-1.9" "" "" "" "" "" "" "" "" "" "" "" "0000034298" "00198" "00046783" "00006" "Unknown" "" "MR (dextromethorphan/dextrorphan) 0.18" "" "" "" "" "" "" "" "" "" "" "" "0000034299" "00198" "00046784" "00006" "Unknown" "" "MR (dextromethorphan/dextrorphan) 0.07" "" "" "" "" "" "" "" "" "" "" "" "0000054240" "04263" "00046489" "01334" "Familial, autosomal dominant" "" "CYP2D6 ultra rapid metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054241" "04265" "00046490" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metabolizer" "" "" "" "" "" "" "" "" "" "" "" "0000054242" "04265" "00046493" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054243" "04265" "00046494" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054244" "04265" "00046495" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054245" "04264" "00046497" "01334" "Familial, autosomal dominant" "" "CYP2D6 poor metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054246" "04265" "00074423" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054247" "04265" "00074424" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054248" "04265" "00074425" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054249" "04265" "00074426" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054250" "04265" "00074427" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054251" "04264" "00074428" "01334" "Familial, autosomal dominant" "" "CYP2D6 poor metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054252" "04265" "00074429" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054253" "04265" "00074430" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054254" "04263" "00074431" "01334" "Familial, autosomal dominant" "" "CYP2D6 ultra-rapid metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054255" "04265" "00074432" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054256" "04263" "00074433" "01334" "Familial, autosomal dominant" "" "CYP2D6 ultra-rapid metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054257" "04265" "00074434" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000054258" "04265" "00074435" "01334" "Familial, autosomal dominant" "" "CYP2D6 intermediate metaboliser" "" "" "" "" "" "" "" "" "" "" "" "0000070547" "04264" "00092215" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070639" "04264" "00092303" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070640" "04264" "00092304" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070641" "04264" "00092305" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070642" "04264" "00092306" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070643" "04264" "00092307" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070644" "04264" "00092308" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070645" "04264" "00092309" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070646" "04264" "00092310" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070647" "04264" "00092311" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070648" "04264" "00092312" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070649" "04264" "00092313" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070650" "04264" "00092314" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070651" "04264" "00092315" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070652" "04264" "00092316" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070653" "04264" "00092317" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070654" "04264" "00092318" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070655" "04264" "00092319" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070656" "04264" "00092320" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070657" "04264" "00092321" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070658" "04264" "00092322" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070677" "04271" "00046434" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070681" "04264" "00046785" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070690" "04265" "00046350" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070691" "04264" "00074484" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070692" "04264" "00074485" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070693" "04265" "00074482" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070694" "04264" "00046469" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070695" "04264" "00046798" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070696" "04265" "00033767" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070697" "04264" "00033765" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070698" "04264" "00033764" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070699" "04264" "00074475" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070700" "04264" "00074486" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" 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"" "" "" "" "" "" "" "" "" "" "0000070720" "04264" "00046421" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070721" "04264" "00046422" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070722" "04264" "00046423" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070723" "04264" "00046424" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070724" "04264" "00046425" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070725" "04264" "00046426" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070726" "04264" "00046427" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070727" "04264" "00046428" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070728" "04264" "00046429" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070729" "04264" "00046430" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070730" "04264" "00046431" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070731" "04264" "00046433" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070732" "04264" "00046432" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070733" "04264" "00046796" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070734" "04265" "00046443" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070735" "04265" "00046442" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070736" "04265" "00033759" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070737" "04265" "00046787" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070738" "04264" "00046439" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070739" "04264" "00046441" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070740" "04264" "00046440" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070741" "04264" "00033762" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070742" "04265" "00033758" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" "0000070743" "04264" "00046446" "00006" "Familial, autosomal dominant" "" "" "" "" "" "" "" "" "" "" "" "" "" ## Screenings ## Do not remove or alter this header ## ## Count = 472 "{{id}}" "{{individualid}}" "{{variants_found}}" "{{owned_by}}" "{{created_by}}" "{{created_date}}" "{{edited_by}}" "{{edited_date}}" "{{Screening/Technique}}" "{{Screening/Template}}" "{{Screening/Tissue}}" "{{Screening/Remarks}}" "0000033819" "00033751" "1" "00006" "00006" "2014-07-14 13:29:12" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033821" "00033753" "1" "00006" "00006" "2014-07-14 21:49:10" "" "" "SEQ" "DNA" "" "" "0000033822" "00033754" "1" "00006" "00006" "2014-07-14 22:02:47" "" "" "PCR;SEQ" "DNA" "" "" "0000033823" "00033755" "1" "00006" "00006" "2014-07-14 22:10:30" "" "" "PCR" "DNA" "" "" "0000033824" "00033756" "1" "00006" "00006" "2014-07-15 21:55:15" "" "" "PCR;SEQ" "DNA" "" "" "0000033825" "00033757" "1" "00006" "00006" "2015-03-01 21:05:28" "" "" "SEQ" "DNA" "" "" "0000033826" "00033758" "1" "00006" "00006" "2015-03-01 21:23:57" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033827" "00033759" "1" "00006" "00006" "2015-03-01 21:32:12" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033828" "00033760" "1" "00006" "00006" "2015-03-03 22:02:06" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033829" "00033761" "1" "00006" "00006" "2015-03-03 22:02:06" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033830" "00033762" "1" "00006" "00006" "2015-03-03 22:02:06" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033831" "00033763" "1" "00006" "00006" "2015-03-03 22:02:06" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033832" "00033764" "1" "00006" "00006" "2015-03-03 22:02:06" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033833" "00033765" "1" "00006" "00006" "2015-03-03 22:02:06" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033834" "00033766" "1" "00006" "00006" "2015-03-03 22:02:06" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000033835" "00033767" "1" "00006" "00006" "2015-03-03 23:22:59" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000034094" "00034026" "1" "00006" "00006" "2015-03-08 11:44:08" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000034095" "00034027" "1" "00006" "00006" "2015-03-08 12:12:58" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000034096" "00034028" "1" "00006" "00006" "2015-03-08 12:18:03" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000035644" "00035574" "1" "01164" "00008" "2015-04-02 13:01:39" "" "" "SEQ" "DNA" "" "" "0000035645" "00035575" "1" "01164" "00008" "2015-04-02 13:01:39" "" "" "SEQ" "DNA" "" "" "0000035646" "00035576" "1" "01164" "00008" "2015-04-02 13:01:39" "" "" "SEQ" "DNA" "" "" "0000035647" "00035577" "1" "01164" "00008" "2015-04-02 13:01:39" "" "" "SEQ" "DNA" "" "" "0000035648" "00035578" "1" "01164" "00008" "2015-04-02 13:01:39" "" "" "SEQ" "DNA" "" "" "0000035649" "00035579" "1" "01164" "00008" "2015-04-02 13:01:39" "" "" "SEQ" "DNA" "" "" "0000035650" "00035580" "1" "01164" "00008" "2015-04-02 13:01:39" "" "" "SEQ" "DNA" "" "" "0000035651" "00035581" "1" "01164" "00008" "2015-04-02 13:01:39" "" "" "SEQ" "DNA" "" "" "0000046443" "00046338" "1" "00006" "00006" "2015-07-07 19:38:44" "" "" "SEQ" "DNA" "" "" "0000046444" "00046339" "1" "00006" "00006" "2015-07-07 19:55:32" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046445" "00046340" "1" "00006" "00006" "2015-07-07 20:02:12" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046447" "00046342" "1" "00006" "00006" "2015-07-07 20:58:52" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046448" "00046343" "1" 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10:09:10" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046567" "00046462" "1" "00006" "00006" "2015-07-12 10:10:21" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046568" "00046463" "1" "00006" "00006" "2015-07-12 10:11:23" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046569" "00046464" "1" "00006" "00006" "2015-07-12 10:11:56" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046570" "00046465" "1" "00006" "00006" "2015-07-12 10:13:01" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046571" "00046466" "1" "00006" "00006" "2015-07-12 10:13:14" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046572" "00046467" "1" "00006" "00006" "2015-07-12 10:21:01" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046573" "00046468" "1" "00006" "00006" "2015-07-12 10:58:13" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046574" "00046469" "1" "00006" "00006" "2015-07-12 11:09:49" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046575" "00046470" "1" "00006" "00006" "2015-07-12 11:10:22" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046576" "00046471" "1" "00006" "00006" "2015-07-12 11:10:35" "00006" "2015-07-12 11:24:59" "SEQ" "DNA" "" "" "0000046577" "00046472" "1" "00006" "00006" "2015-07-12 11:39:53" "" "" "SEQ" "DNA" "" "" "0000046578" "00046473" "1" "00006" "00006" "2015-07-12 20:24:48" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046579" "00046474" "1" "00006" "00006" "2015-07-12 20:25:02" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046580" "00046475" "1" "00006" "00006" "2015-07-12 20:32:28" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046581" "00046476" "1" "00006" "00006" "2015-07-12 20:32:41" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046582" "00046477" "1" "00006" "00006" "2015-07-12 20:32:51" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046583" "00046478" "1" "00006" "00006" "2015-07-12 20:33:00" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046584" "00046479" "1" "00006" "00006" "2015-07-12 20:33:09" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046585" "00046480" "1" "00006" "00006" "2015-07-12 20:33:18" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046586" "00046481" "1" "00006" "00006" "2015-07-12 20:33:27" "00006" "2015-07-12 20:52:14" "SEQ" "DNA" "" "" "0000046587" "00046482" "1" "00006" "00006" "2015-07-12 20:55:48" "" "" "SEQ" "DNA" "" "" "0000046588" "00046483" "1" "00006" "00006" "2015-07-12 20:55:56" "" "" "SEQ" "DNA" "" "" "0000046589" "00046484" "1" "00006" "00006" "2015-07-12 20:56:08" "" "" "SEQ" "DNA" "" "" "0000046590" "00046485" "1" "00006" "00006" "2015-07-12 20:56:17" "" "" "SEQ" "DNA" "" "" "0000046591" "00046486" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-20 15:38:53" "SEQ;SEQ-PB" "DNA" "" "" "0000046592" "00046487" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 09:21:03" "SEQ;SEQ-PB" "DNA" "" "" "0000046593" "00046488" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 09:44:16" "SEQ;SEQ-PB" "DNA" "" "" "0000046594" "00046489" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 10:44:28" "SEQ;SEQ-PB" "DNA" "" "" "0000046595" "00046490" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 10:48:38" "SEQ;SEQ-PB" "DNA" "" "" "0000046596" "00046491" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 11:01:28" "SEQ;SEQ-PB" "DNA" "" "" "0000046597" "00046492" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 11:01:52" "SEQ;SEQ-PB" "DNA" "" "" "0000046599" "00046494" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 13:32:46" "SEQ;SEQ-PB" "DNA" "" "" "0000046600" "00046495" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 13:33:21" "SEQ;SEQ-PB" "DNA" "" "" "0000046601" "00046496" "1" "00006" "00006" "2015-07-12 21:35:30" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000046602" "00046497" "1" "01334" "00006" "2015-07-12 21:35:30" "00006" "2015-07-21 13:34:22" "SEQ;SEQ-PB" "DNA" "" "" "0000046717" "00046493" "1" "01334" "00006" "2015-07-21 12:52:36" "" "" "SEQ-PB" "DNA" "" "" "0000046882" "00046773" "1" "00006" "00006" "2015-07-24 13:01:21" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046883" "00046774" "1" "00006" "00006" "2015-07-24 13:38:15" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000046884" "00046775" "1" "00006" "00006" "2015-07-24 14:34:25" "" "" "SEQ" "DNA" "" "" "0000046885" "00046776" "1" "00006" "00006" "2015-07-24 14:40:27" "" "" "SEQ" "DNA" "" "" "0000046886" "00046777" "1" "00006" "00006" "2015-07-24 14:57:38" "" "" "SEQ" "DNA" "" "" "0000046887" "00046778" "1" "00006" "00006" "2015-07-24 15:20:50" "" "" "SEQ" "DNA" "" "" "0000046888" "00046779" "1" "00006" "00006" "2015-07-24 16:50:27" "" "" "SEQ" "DNA" "" "" "0000046889" "00046780" "1" "00006" "00006" "2015-07-24 17:05:25" "" "" "SEQ" "DNA" "" "" "0000046890" "00046781" "1" "00006" "00006" "2015-07-24 17:29:46" "" "" "SEQ" "DNA" "" "" "0000046892" "00046783" "1" "00006" "00006" "2015-07-24 19:24:11" "" "" "SEQ" "DNA" "" "" "0000046893" "00046784" "1" "00006" "00006" "2015-07-24 19:25:54" "" "" "SEQ" "DNA" "" "" "0000046894" "00046785" "1" "00006" "00006" "2015-07-24 20:09:10" "" "" "SEQ" "DNA" "" "" "0000046896" "00046787" "1" "00006" "00006" "2015-07-24 20:22:38" "" "" "SEQ" "DNA" "" "" "0000046905" "00046796" "1" "00006" "00006" "2015-07-25 12:15:12" "" "" "SEQ" "DNA" "" "" "0000046906" "00046797" "1" "00006" "00006" "2015-07-25 12:26:15" "" "" "SEQ" "DNA" "" "" "0000046907" "00046798" "1" "00006" "00006" "2015-07-25 13:00:39" "" "" "SEQ" "DNA" "" "" "0000046908" "00046799" "1" "00006" "00006" "2015-07-25 13:21:43" "" "" "SEQ" "DNA" "" "" "0000046909" "00046800" "1" "00006" "00006" "2015-07-25 13:35:32" "" "" "SEQ" "DNA" "" "" "0000046910" "00046801" "1" "00006" "00006" "2015-07-25 14:19:19" "" "" "SEQ" "DNA" "" "" "0000046911" "00046802" "1" "00006" "00006" "2015-07-25 14:34:23" "" "" "SEQ" "DNA" "" "" "0000052002" "00052055" "1" "00006" "00006" "2015-10-12 16:22:20" "" "" "SEQ" "DNA" "" "" "0000064784" "00064644" "1" "00006" "00006" "2016-05-05 13:55:18" "" "" "SEQ" "DNA" "" "" "0000064785" "00064645" "1" "00006" "00006" "2016-05-05 15:19:41" "" "" "SEQ" "DNA" "" "" "0000064786" "00064646" "1" "00006" "00006" "2016-05-05 15:27:31" "" "" "SEQ" "DNA" "" "" "0000064787" "00064647" "1" "00006" "00006" "2016-05-05 15:39:03" "" "" "SEQ" "DNA" "" "" "0000064788" "00064648" "1" "00006" "00006" "2016-05-05 17:20:47" "" "" "SEQ" "DNA" "" "" "0000064789" "00064649" "1" "00006" "00006" "2016-05-05 17:35:23" "" "" "SEQ" "DNA" "" "" "0000064790" "00064650" "1" "00006" "00006" "2016-05-05 18:23:53" "" "" "SEQ" "DNA" "" "" "0000064791" "00064651" "1" "00006" "00006" "2016-05-05 19:29:00" "" "" "SEQ" "DNA" "" "" "0000064792" "00064652" "1" "00006" "00006" "2016-05-05 21:44:45" "" "" "SEQ" "DNA" "" "" "0000064798" "00064658" "1" "00006" "00006" "2016-05-06 16:24:45" "" "" "SEQ" "DNA" "" "" "0000064799" "00064659" "1" "00006" "00006" "2016-05-06 16:28:28" "" "" "SEQ" "DNA" "" "" "0000064800" "00064660" "1" "00006" "00006" "2016-05-06 17:03:53" "" "" "SEQ" "DNA" "" "" "0000064801" "00064661" "1" "00006" "00006" "2016-05-06 19:18:45" "" "" "SEQ" "DNA" "" "" "0000064802" "00064662" "1" "00006" "00006" "2016-05-06 19:25:30" "" "" "SEQ" "DNA" "" "" "0000064803" "00064663" "1" "00006" "00006" "2016-05-06 19:46:23" "" "" "SEQ" "DNA" "" "" "0000064804" "00064664" "1" "00006" "00006" "2016-05-06 20:08:24" "" "" "SEQ" "DNA" "" "" "0000074584" "00074423" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074585" "00074424" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074586" "00074425" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074587" "00074426" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074588" "00074427" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074589" "00074428" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074590" "00074429" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074591" "00074430" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074592" "00074431" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074593" "00074432" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074594" "00074433" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074595" "00074434" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074596" "00074435" "1" "01334" "00006" "2016-06-29 19:27:10" "" "" "SEQ;SEQ-PB" "DNA" "" "" "0000074637" "00074473" "1" "00006" "00006" "2016-07-03 21:53:00" "" "" "SEQ" "DNA" "" "" "0000074638" "00074474" "1" "00006" "00006" "2016-07-03 21:55:44" "" "" "SEQ" "DNA" "" "" "0000074639" "00074475" "1" "00006" "00006" "2016-07-03 22:05:43" "" "" "SEQ" "DNA" "" "" "0000074640" "00074476" "1" "00006" "00006" "2016-07-03 22:34:33" "" "" "SEQ" "DNA" "" "" "0000074641" "00074477" "1" "00006" "00006" "2016-07-03 22:55:25" "" "" "SEQ" "DNA" "" "" "0000074643" "00074479" "1" "00006" "00006" "2016-07-04 21:02:48" "" "" "SEQ" "DNA" "" "" "0000074644" "00074480" "1" "00006" "00006" "2016-07-04 21:13:56" "" "" "SEQ" "DNA" "" "" "0000074645" "00074481" "1" "00006" "00006" "2016-07-04 21:24:37" "" "" "SEQ" "DNA" "" "" "0000074646" "00074482" "1" "00006" "00006" "2016-07-04 21:33:18" "" "" "SEQ" "DNA" "" "" "0000074647" "00074483" "1" "00006" "00006" "2016-07-04 21:46:31" "" "" "SEQ" "DNA" "" "" "0000074648" "00074484" "1" "00006" "00006" "2016-07-04 22:02:08" "" "" "SEQ" "DNA" "" "" "0000074649" "00074485" "1" "00006" "00006" "2016-07-04 22:10:05" "" "" "SEQ" "DNA" "" "" "0000074650" "00074486" "1" "00006" "00006" "2016-07-04 22:22:14" "" "" "SEQ" "DNA" "" "" "0000074651" "00074487" "1" "00006" "00006" "2016-07-04 22:46:37" "" "" "SEQ" "DNA" "" "" "0000074652" "00074488" "1" "00006" "00006" "2016-07-04 22:53:38" "" "" "SEQ" "DNA" "" "" "0000074653" "00074489" "1" "00006" "00006" "2016-07-04 22:59:09" "" "" "SEQ" "DNA" "" "" "0000074672" "00074508" "1" "00006" "00006" "2016-07-05 21:25:17" "" "" "SEQ" "DNA" "" "" "0000074673" "00074509" "1" "00006" "00006" "2016-07-05 21:46:32" "" "" "SEQ" "DNA" "" "" "0000074674" "00074510" "1" "00006" "00006" "2016-07-05 21:56:03" "" "" "SEQ" "DNA" "" "" "0000074675" "00074511" "1" "00006" "00006" "2016-07-05 22:01:28" "" "" "SEQ" "DNA" "" "" "0000074677" "00074513" "1" "00006" "00006" "2016-07-05 22:08:15" "" "" "SEQ" "DNA" "" "" "0000074678" "00074514" "1" "00006" "00006" "2016-07-05 22:13:38" "" "" "SEQ" "DNA" "" "" "0000074679" "00074515" "1" "00006" "00006" "2016-07-05 22:21:13" "" "" "SEQ" "DNA" "" "" "0000074680" "00074516" "1" "00006" "00006" "2016-07-05 22:25:43" "" "" "SEQ" "DNA" "" "" "0000074681" "00074517" "1" "00006" "00006" "2016-07-05 22:33:52" "" "" "SEQ" "DNA" "" "" "0000092356" "00092215" "1" "00006" "00006" "2016-12-16 15:31:53" "" "" "SEQ-NG" "DNA" "" "" "0000092437" "00092297" "1" "00006" "00006" "2016-12-23 16:58:01" "" "" "SEQ" "DNA" "" "" "0000092438" "00092298" "1" "00006" "00006" "2016-12-23 16:58:01" "" "" "SEQ;PCR" "DNA" "" "" "0000092439" "00092299" "1" "00006" "00006" "2016-12-23 19:05:19" "" "" "SEQ" "DNA" "" "" "0000092440" "00092300" "1" "00006" "00006" "2016-12-23 19:05:19" "" "" "SEQ;PCR" "DNA" "" "" "0000092441" "00092301" "1" "00006" "00006" "2016-12-23 19:32:37" "" "" "SEQ" "DNA" "" "" "0000092442" "00092302" "1" "00006" "00006" "2016-12-23 19:32:37" "" "" "SEQ;PCR" "DNA" "" "" "0000092443" "00092303" "1" "00006" "00006" "2016-12-24 19:58:25" "" "" "SEQ;PCR" "DNA" "" "" "0000092444" "00092304" "1" "00006" "00006" "2016-12-24 19:58:25" "" "" "SEQ;PCR" "DNA" "" "" "0000092445" "00092305" "1" "00006" "00006" "2016-12-27 10:46:24" "" "" "SEQ;PCR" "DNA" "" "" "0000092446" "00092306" "1" "00006" "00006" "2016-12-27 10:46:24" "" "" "SEQ;PCR" "DNA" "" "" "0000092447" "00092307" "1" "00006" "00006" "2016-12-27 11:16:58" "" "" "SEQ;PCR" "DNA" "" "" "0000092448" "00092308" "1" "00006" "00006" "2016-12-27 11:16:58" "" "" "SEQ;PCR" "DNA" "" "" "0000092449" "00092309" "1" "00006" "00006" "2016-12-27 11:24:20" "" "" "SEQ;PCR" "DNA" "" "" "0000092450" "00092310" "1" "00006" "00006" "2016-12-27 11:24:20" "" "" "SEQ;PCR" "DNA" "" "" "0000092451" "00092311" "1" "00006" "00006" "2016-12-27 11:32:18" "" "" "SEQ;PCR" "DNA" "" "" "0000092452" "00092312" "1" "00006" "00006" "2016-12-27 11:32:18" "" "" "SEQ;PCR" "DNA" "" "" "0000092453" "00092313" "1" "00006" "00006" "2016-12-27 11:40:48" "" "" "SEQ;PCR" "DNA" "" "" "0000092454" "00092314" "1" "00006" "00006" "2016-12-27 11:40:48" "" "" "SEQ;PCR" "DNA" "" "" "0000092455" "00092315" "1" "00006" "00006" "2016-12-27 11:49:15" "" "" "SEQ;PCR" "DNA" "" "" "0000092456" "00092316" "1" "00006" "00006" "2016-12-27 11:49:15" "" "" "SEQ;PCR" "DNA" "" "" "0000092457" "00092317" "1" "00006" "00006" "2016-12-27 11:59:28" "" "" "SEQ;PCR" "DNA" "" "" "0000092458" "00092318" "1" "00006" "00006" "2016-12-27 11:59:28" "" "" "SEQ;PCR" "DNA" "" "" "0000092459" "00092319" "1" "00006" "00006" "2016-12-27 12:06:45" "" "" "SEQ;PCR" "DNA" "" "" "0000092460" "00092320" "1" "00006" "00006" "2016-12-27 12:06:45" "" "" "SEQ;PCR" "DNA" "" "" "0000092461" "00092321" "1" "00006" "00006" "2016-12-27 12:19:21" "" "" "SEQ;PCR" "DNA" "" "" "0000092462" "00092322" "1" "00006" "00006" "2016-12-27 12:19:21" "" "" "SEQ;PCR" "DNA" "" "" "0000092489" "00092323" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092490" "00092324" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092491" "00092325" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092493" "00092327" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092494" "00092328" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092495" "00092329" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092496" "00092330" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092497" "00092331" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092498" "00092332" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092499" "00092333" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092500" "00092334" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092501" "00092335" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092502" "00092336" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092503" "00092337" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092504" "00092338" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092505" "00092339" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092506" "00092340" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092507" "00092341" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092508" "00092342" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092509" "00092343" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092510" "00092344" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092511" "00092345" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092512" "00092346" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092513" "00092347" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092514" "00092348" "1" "00006" "00006" "2016-12-27 13:49:29" "" "" "SEQ" "DNA" "" "" "0000092516" "00092349" "1" "00006" "00006" "2016-12-28 12:07:33" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000101659" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101660" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101661" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101662" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101663" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101664" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101665" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101666" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101667" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101668" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101669" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101670" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101671" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101672" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101673" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101674" "00101233" "1" "00006" "00006" "2017-03-22 19:05:35" "" "" "expr" "protein" "" "" "0000101675" "00101233" "1" "00006" "00006" "2017-03-22 19:23:07" "" "" "expr" "protein" "" "" "0000101676" "00101233" "1" "00006" "00006" "2017-03-22 19:23:07" "" "" "expr" "protein" "" "" "0000101677" "00101233" "1" "00006" "00006" "2017-03-22 19:23:07" "" "" "expr" "protein" "" "" "0000101678" "00101233" "1" "00006" "00006" "2017-03-22 19:46:33" "" "" "expr" "protein" "" "" "0000101686" "00101233" "1" "00006" "00006" "2017-03-24 09:38:19" "" "" "expr" "protein" "" "" "0000101687" "00101233" "1" "00006" "00006" "2017-03-24 09:47:39" "" "" "expr" "protein" "" "" "0000101688" "00101233" "1" "00006" "00006" "2017-03-24 09:51:03" "" "" "expr" "protein" "" "" "0000101689" "00101233" "1" "00006" "00006" "2017-03-24 09:54:51" "" "" "expr" "protein" "" "" "0000185047" "00184080" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185048" "00184081" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185049" "00184082" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185050" "00184083" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185051" "00184084" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185052" "00184085" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185053" "00184086" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185054" "00184087" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185055" "00184088" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185056" "00184089" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185057" "00184090" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185058" "00184091" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185059" "00184092" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185060" "00184093" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185061" "00184094" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185062" "00184095" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185063" "00184096" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185064" "00184097" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185065" "00184098" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185066" "00184099" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185067" "00184100" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185068" "00184101" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185069" "00184102" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185070" "00184103" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185071" "00184104" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185072" "00184105" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185073" "00184106" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185074" "00184107" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185075" "00184108" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185076" "00184109" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185077" "00184110" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185078" "00184111" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185079" "00184112" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185080" "00184113" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185081" "00184114" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185082" "00184115" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185083" "00184116" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185084" "00184117" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185085" "00184118" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185086" "00184119" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185087" "00184120" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185088" "00184121" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185089" "00184122" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185090" "00184123" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185091" "00184124" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185092" "00184125" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185093" "00184126" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185094" "00184127" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185095" "00184128" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185096" "00184129" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185097" "00184130" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185098" "00184131" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185099" "00184132" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185100" "00184133" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185101" "00184134" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185102" "00184135" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185103" "00184136" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185104" "00184137" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185105" "00184138" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185106" "00184139" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185107" "00184140" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185108" "00184141" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185109" "00184142" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185110" "00184143" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185111" "00184144" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185112" "00184145" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185113" "00184146" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185114" "00184147" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185115" "00184148" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185116" "00184149" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185117" "00184150" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185118" "00184151" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185119" "00184152" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185120" "00184153" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185121" "00184154" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185122" "00184155" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185123" "00184156" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185124" "00184157" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185125" "00184158" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185126" "00184159" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185127" "00184160" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185128" "00184161" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185129" "00184162" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185130" "00184163" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185131" "00184164" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185132" "00184165" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185133" "00184166" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185134" "00184167" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185135" "00184168" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185136" "00184169" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185137" "00184170" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185138" "00184171" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185139" "00184172" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185140" "00184173" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185141" "00184174" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185142" "00184175" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185143" "00184176" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185144" "00184177" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185145" "00184178" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185146" "00184179" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185147" "00184180" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185148" "00184181" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185149" "00184182" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185150" "00184183" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185151" "00184184" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185152" "00184185" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185153" "00184186" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185154" "00184187" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185155" "00184188" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185156" "00184189" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185157" "00184190" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185158" "00184191" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185159" "00184192" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185160" "00184193" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185161" "00184194" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185162" "00184195" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185163" "00184196" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185164" "00184197" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185165" "00184198" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185166" "00184199" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185167" "00184200" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185168" "00184201" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185169" "00184202" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185170" "00184203" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185171" "00184204" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185172" "00184205" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185173" "00184206" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185174" "00184207" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185175" "00184208" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185176" "00184209" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185177" "00184210" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185178" "00184211" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185179" "00184212" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185180" "00184213" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185181" "00184214" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185182" "00184215" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185183" "00184216" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185184" "00184217" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185185" "00184218" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185186" "00184219" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185187" "00184220" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185188" "00184221" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185189" "00184222" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185190" "00184223" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185191" "00184224" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185192" "00184225" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185193" "00184226" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185194" "00184227" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185195" "00184228" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185196" "00184229" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185197" "00184230" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185198" "00184231" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185199" "00184232" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185200" "00184233" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185201" "00184234" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185202" "00184235" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185203" "00184236" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185204" "00184237" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185205" "00184238" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185206" "00184239" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185207" "00184240" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185208" "00184241" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185209" "00184242" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185210" "00184243" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185211" "00184244" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185212" "00184245" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185213" "00184246" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185214" "00184247" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185215" "00184248" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185216" "00184249" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185217" "00184250" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185218" "00184251" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185219" "00184252" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185220" "00184253" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185221" "00184254" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185222" "00184255" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185223" "00184256" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185224" "00184257" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185225" "00184258" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185226" "00184259" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185227" "00184260" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185228" "00184261" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185229" "00184262" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185230" "00184263" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185231" "00184264" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185232" "00184265" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185233" "00184266" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185234" "00184267" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185235" "00184268" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185236" "00184269" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185237" "00184270" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185238" "00184271" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185239" "00184272" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185240" "00184273" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185241" "00184274" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185242" "00184275" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185243" "00184276" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185244" "00184277" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000185245" "00184278" "1" "02562" "00006" "2018-10-27 20:13:16" "" "" "arraySNP;PCRq" "DNA" "saliva" "gene panel CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, TPMT, SLCO1B1, VKORC1" "0000294309" "00293141" "1" "03575" "00006" "2020-03-11 19:30:02" "" "" "arraySNP" "DNA" "" "Infinium Global Screening Array v1.0" "0000294310" "00293142" "1" "03575" "00006" "2020-03-11 19:30:02" "" "" "arraySNP" "DNA" "" "Infinium Global Screening Array v1.0" "0000294311" "00293143" "1" "03575" "00006" "2020-03-11 19:30:02" "" "" "arraySNP" "DNA" "" "Infinium Global Screening Array v1.0" "0000306037" "00304908" "1" "03575" "00006" "2020-06-24 11:55:42" "" "" "arraySNP" "DNA" "" "Infinium Global Screening Array v1.0" ## Screenings_To_Genes ## Do not remove or alter this header ## ## Count = 269 "{{screeningid}}" "{{geneid}}" "0000033819" "CYP2D6" "0000033821" "CYP2D6" "0000033822" "CYP2D6" "0000033823" "CYP2D6" "0000033824" "CYP2D6" "0000033825" "CYP2D6" "0000033826" "CYP2D6" "0000033827" "CYP2D6" "0000033828" "CYP2D6" "0000033829" "CYP2D6" "0000033830" "CYP2D6" "0000033831" "CYP2D6" "0000033832" "CYP2D6" "0000033833" "CYP2D6" "0000033834" "CYP2D6" "0000033835" "CYP2D6" "0000034094" "CYP2D6" "0000034095" "CYP2D6" "0000034096" "CYP2D6" "0000035644" "CYP2D6" "0000035645" "CYP2D6" "0000035646" "CYP2D6" "0000035647" "CYP2D6" "0000035648" "CYP2D6" "0000035649" "CYP2D6" "0000035650" "CYP2D6" "0000035651" "CYP2D6" "0000046443" "CYP2D6" "0000046444" "CYP2D6" "0000046445" "CYP2D6" "0000046447" "CYP2D6" "0000046448" "CYP2D6" "0000046449" "CYP2D6" "0000046450" "CYP2D6" "0000046451" "CYP2D6" "0000046452" "CYP2D6" "0000046453" "CYP2D6" "0000046454" "CYP2D6" "0000046455" "CYP2D6" "0000046456" "CYP2D6" "0000046457" "CYP2D6" "0000046458" "CYP2D6" "0000046518" "CYP2D6" "0000046523" "CYP2D6" "0000046524" "CYP2D6" "0000046525" "CYP2D6" "0000046526" "CYP2D6" "0000046527" "CYP2D6" "0000046528" "CYP2D6" "0000046529" "CYP2D6" "0000046530" "CYP2D6" "0000046531" "CYP2D6" "0000046532" "CYP2D6" "0000046533" "CYP2D6" "0000046534" "CYP2D6" "0000046535" "CYP2D6" "0000046536" "CYP2D6" "0000046537" "CYP2D6" "0000046538" "CYP2D6" "0000046539" "CYP2D6" "0000046544" "CYP2D6" "0000046545" "CYP2D6" "0000046546" "CYP2D6" "0000046547" "CYP2D6" "0000046548" "CYP2D6" "0000046549" "CYP2D6" "0000046550" "CYP2D6" "0000046551" "CYP2D6" "0000046552" "CYP2D6" "0000046553" "CYP2D6" "0000046554" "CYP2D6" "0000046555" "CYP2D6" "0000046556" "CYP2D6" "0000046557" "CYP2D6" "0000046558" "CYP2D6" "0000046559" "CYP2D6" "0000046560" "CYP2D6" "0000046561" "CYP2D6" "0000046562" "CYP2D6" "0000046565" "CYP2D6" "0000046566" "CYP2D6" "0000046567" "CYP2D6" "0000046568" "CYP2D6" "0000046569" "CYP2D6" "0000046570" "CYP2D6" "0000046571" "CYP2D6" "0000046572" "CYP2D6" "0000046573" "CYP2D6" "0000046574" "CYP2D6" "0000046575" "CYP2D6" "0000046576" "CYP2D6" "0000046577" "CYP2D6" "0000046578" "CYP2D6" "0000046579" "CYP2D6" "0000046580" "CYP2D6" "0000046581" "CYP2D6" "0000046582" "CYP2D6" "0000046583" "CYP2D6" "0000046584" "CYP2D6" "0000046585" "CYP2D6" "0000046586" "CYP2D6" "0000046587" "CYP2D6" "0000046588" "CYP2D6" "0000046589" "CYP2D6" "0000046590" "CYP2D6" "0000046591" "CYP2D6" "0000046592" "CYP2D6" "0000046593" "CYP2D6" "0000046594" "CYP2D6" "0000046595" "CYP2D6" "0000046596" "CYP2D6" "0000046597" "CYP2D6" "0000046599" "CYP2D6" "0000046600" "CYP2D6" "0000046601" "CYP2D6" "0000046602" "CYP2D6" "0000046717" "CYP2D6" "0000046882" "CYP2D6" "0000046883" "CYP2D6" "0000046884" "CYP2D6" "0000046885" "CYP2D6" "0000046886" "CYP2D6" "0000046887" "CYP2D6" "0000046888" "CYP2D6" "0000046889" "CYP2D6" "0000046890" "CYP2D6" "0000046892" "CYP2D6" "0000046893" "CYP2D6" "0000046894" "CYP2D6" "0000046896" "CYP2D6" "0000046905" "CYP2D6" "0000046906" "CYP2D6" "0000046907" "CYP2D6" "0000046908" "CYP2D6" "0000046909" "CYP2D6" "0000046910" "CYP2D6" "0000046911" "CYP2D6" "0000052002" "CYP2D6" "0000064784" "CYP2D6" "0000064785" "CYP2D6" "0000064786" "CYP2D6" "0000064787" "CYP2D6" "0000064788" "CYP2D6" "0000064789" "CYP2D6" "0000064790" "CYP2D6" "0000064791" "CYP2D6" "0000064792" "CYP2D6" "0000064798" "CYP2D6" "0000064799" "CYP2D6" "0000064800" "CYP2D6" "0000064801" "CYP2D6" "0000064802" "CYP2D6" "0000064803" "CYP2D6" "0000064804" "CYP2D6" "0000074584" "CYP2D6" "0000074585" "CYP2D6" "0000074586" "CYP2D6" "0000074587" "CYP2D6" "0000074588" "CYP2D6" "0000074589" "CYP2D6" "0000074590" "CYP2D6" "0000074591" "CYP2D6" "0000074592" "CYP2D6" "0000074593" "CYP2D6" "0000074594" "CYP2D6" "0000074595" "CYP2D6" "0000074596" "CYP2D6" "0000074637" "CYP2D6" "0000074638" "CYP2D6" "0000074639" "CYP2D6" "0000074640" "CYP2D6" "0000074641" "CYP2D6" "0000074643" "CYP2D6" "0000074644" "CYP2D6" "0000074645" "CYP2D6" "0000074646" "CYP2D6" "0000074647" "CYP2D6" "0000074648" "CYP2D6" "0000074649" "CYP2D6" "0000074650" "CYP2D6" "0000074651" "CYP2D6" "0000074652" "CYP2D6" "0000074653" "CYP2D6" "0000074672" "CYP2D6" "0000074673" "CYP2D6" "0000074674" "CYP2D6" "0000074675" "CYP2D6" "0000074677" "CYP2D6" "0000074678" "CYP2D6" "0000074679" "CYP2D6" "0000074680" "CYP2D6" "0000074681" "CYP2D6" "0000092356" "CYP2D6" "0000092437" "CYP2D6" "0000092438" "CYP2D6" "0000092439" "CYP2D6" "0000092440" "CYP2D6" "0000092441" "CYP2D6" "0000092442" "CYP2D6" "0000092443" "CYP2D6" "0000092444" "CYP2D6" "0000092445" "CYP2D6" "0000092446" "CYP2D6" "0000092447" "CYP2D6" "0000092448" "CYP2D6" "0000092449" "CYP2D6" "0000092450" "CYP2D6" "0000092451" "CYP2D6" "0000092452" "CYP2D6" "0000092453" "CYP2D6" "0000092454" "CYP2D6" "0000092455" "CYP2D6" "0000092456" "CYP2D6" "0000092457" "CYP2D6" "0000092458" "CYP2D6" "0000092459" "CYP2D6" "0000092460" "CYP2D6" "0000092461" "CYP2D6" "0000092462" "CYP2D6" "0000092489" "CYP2D6" "0000092490" "CYP2D6" "0000092491" "CYP2D6" "0000092493" "CYP2D6" "0000092494" "CYP2D6" "0000092495" "CYP2D6" "0000092496" "CYP2D6" "0000092497" "CYP2D6" "0000092498" "CYP2D6" "0000092499" "CYP2D6" "0000092500" "CYP2D6" "0000092501" "CYP2D6" "0000092502" "CYP2D6" "0000092503" "CYP2D6" "0000092504" "CYP2D6" "0000092505" "CYP2D6" "0000092506" "CYP2D6" "0000092507" "CYP2D6" "0000092508" "CYP2D6" "0000092509" "CYP2D6" "0000092510" "CYP2D6" "0000092511" "CYP2D6" "0000092512" "CYP2D6" "0000092513" "CYP2D6" "0000092514" "CYP2D6" "0000092516" "CYP2D6" "0000101659" "CYP2D6" "0000101660" "CYP2D6" "0000101661" "CYP2D6" "0000101662" "CYP2D6" "0000101663" "CYP2D6" "0000101664" "CYP2D6" "0000101665" "CYP2D6" "0000101666" "CYP2D6" "0000101667" "CYP2D6" "0000101668" "CYP2D6" "0000101669" "CYP2D6" "0000101670" "CYP2D6" "0000101671" "CYP2D6" "0000101672" "CYP2D6" "0000101673" "CYP2D6" "0000101674" "CYP2D6" "0000101675" "CYP2D6" "0000101676" "CYP2D6" "0000101677" "CYP2D6" "0000101678" "CYP2D6" "0000101686" "CYP2D6" "0000101687" "CYP2D6" "0000101688" "CYP2D6" "0000101689" "CYP2D6" ## Variants_On_Genome ## Do not remove or alter this header ## ## Please note that not necessarily all variants found in the given individuals are shown. This output is restricted to variants in the selected gene. ## Count = 2633 "{{id}}" "{{allele}}" "{{effectid}}" "{{chromosome}}" "{{position_g_start}}" "{{position_g_end}}" "{{type}}" "{{average_frequency}}" "{{owned_by}}" "{{VariantOnGenome/DBID}}" "{{VariantOnGenome/DNA}}" "{{VariantOnGenome/Frequency}}" "{{VariantOnGenome/Reference}}" "{{VariantOnGenome/Restriction_site}}" "{{VariantOnGenome/Published_as}}" "{{VariantOnGenome/Remarks}}" "{{VariantOnGenome/Genetic_origin}}" "{{VariantOnGenome/Segregation}}" "{{VariantOnGenome/dbSNP}}" "{{VariantOnGenome/VIP}}" "{{VariantOnGenome/Methylation}}" "{{VariantOnGenome/ISCN}}" "{{VariantOnGenome/DNA/hg38}}" "{{VariantOnGenome/ClinVar}}" "{{VariantOnGenome/ClinicalClassification}}" "{{VariantOnGenome/ClinicalClassification/Method}}" "0000060613" "1" "90" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "34/42 cases" "{PMID:Gough 1990:01978251}, {OMIM124030:0001}" "BstNI-" "" "" "Germline" "yes" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000060614" "1" "30" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "{PMID:Gough 1990:01978251}" "" "" "" "Germline" "-" "" "0" "" "" "g.42129819G>T" "" "likely benign" "" "0000060615" "1" "30" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "{PMID:Gough 1990:01978251}" "" "" "" "Germline" "-" "" "0" "" "" "g.42129809T>C" "" "likely benign" "" "0000060616" "1" "10" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "{PMID:Gough 1990:01978251}" "" "" "" "Germline" "-" "" "0" "" "" "g.42129796G>C" "" "benign" "" "0000060618" "1" "90" "22" "42521918" "42534076" "del" "0" "00006" "CYP2D6_000008" "g.42521918_42534076del" "" "{PMID:Steen 1995:08634695}, {OMIM124030:0002}" "" "" "12.1 kb deletion (13 kb XbaI allele), CYP2D6D allele" "Germline" "yes" "" "0" "" "" "g.42125913_42138071del" "" "pathogenic" "" "0000060619" "1" "90" "22" "42521918" "42534076" "del" "0" "00006" "CYP2D6_000008" "g.42521918_42534076del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "CYP2D6 deletion" "reference haplotype CYP2D6*5 [deleted]" "Germline" "yes" "" "0" "" "" "g.42125913_42138071del" "" "pathogenic" "" "0000060620" "3" "90" "22" "42522575" "42526794" "" "0" "00006" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "1/42 cases" "{PMID:Gough 1990:01978251}, {OMIM124030:0002}" "" "CYP2D6 deletion" "11.5 kb XbaI allele" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000060621" "1" "30" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Gough 1990:01978251}" "" "" "" "Germline" "-" "" "0" "" "" "g.42130692G>A" "" "likely benign" "" "0000060622" "1" "10" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Gough 1990:01978251}" "" "" "" "Germline" "-" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000060623" "1" "30" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Gough 1990:01978251}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "-" "" "0" "" "" "" "" "likely benign" "" "0000060624" "1" "90" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "{PMID:Hanioka 1990:01978565}, {OMIM124030:0001}" "BstNI-" "G1934A" "44 kb XbaI allele" "Germline" "yes" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000060625" "2" "90" "22" "42522575" "42526794" "" "0" "00006" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "{PMID:Hanioka 1990:01978565}, {OMIM124030:0002}" "" "CYP2D6 deletion" "11.5 kb XbaI allele" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000060626" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Hanioka 1990:01978565}" "" "C188T (P34S)" "44 kb XbaI allele" "Germline" "-" "" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000060627" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "{PMID:Hanioka 1990:01978565}" "" "C1062A (L91M)" "44 kb XbaI allele" "Germline" "-" "" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000060628" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "{PMID:Hanioka 1990:01978565}" "" "A1072G (H94R)" "44 kb XbaI allele" "Germline" "-" "" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000060629" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Hanioka 1990:01978565}" "" "G4268C (S486T)" "44 kb XbaI allele\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "-" "" "0" "" "" "" "" "VUS" "" "0000060630" "1" "30" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "{PMID:Hanioka 1990:01978565}" "" "C1085G" "44 kb XbaI allele" "Germline" "-" "" "0" "" "" "g.42129796G>C" "" "likely benign" "" "0000060631" "1" "30" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Hanioka 1990:01978565}" "" "G1749C" "44 kb XbaI allele" "Germline" "-" "" "0" "" "" "g.42129130C>G" "" "likely benign" "" "0000060632" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2D" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000060633" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2D\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000060634" "1" "99" "22" "42524178" "42524180" "del" "0" "00006" "CYP2D6_000014" "g.42524178_42524180del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2615_2617delAAG" "reference haplotype CYP2D6*9; decreased activity" "Germline" "yes" "rs5030656" "0" "" "" "g.42128176_42128178del" "" "pathogenic" "" "0000060635" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*10A" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000060636" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*10A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000060637" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*10A" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000060638" "1" "99" "22" "42524244" "42524244" "del" "0.0123819" "00006" "CYP2D6_000016" "g.42524244del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2549delA (259fs)" "reference haplotype CYP2D6*3 (CYP2D6*3A)" "Germline" "yes" "rs35742686" "0" "" "" "g.42128242del" "" "pathogenic" "" "0000060639" "1" "99" "22" "42525086" "42525086" "del" "0.00791688" "00006" "CYP2D6_000017" "g.42525086del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1707delT (118fs)" "reference haplotype CYp2D6*6A (CYP2D6A); no activity" "Germline" "yes" "rs5030655" "0" "" "" "g.42129084del" "" "pathogenic" "" "0000060640" "1" "99" "22" "42523858" "42523858" "subst" "0.00133446" "00006" "CYP2D6_000018" "g.42523858T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2935A>C" "reference haplotype CY2PD6*7; no activity" "Germline" "yes" "rs5030867" "0" "" "" "g.42127856T>G" "" "pathogenic" "" "0000060641" "1" "99" "22" "42525035" "42525035" "subst" "6.80151E-5" "00006" "CYP2D6_000019" "g.42525035C>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1758G>T (G169X)" "reference haplotype CYP2D6*8; no activity (in patient)" "Germline" "yes" "rs5030865" "0" "" "" "g.42129033C>A" "" "pathogenic" "" "0000060642" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*8" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000060643" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*8" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000060644" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*8\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000060645" "1" "99" "22" "42525912" "42525912" "subst" "0.000118933" "00006" "CYP2D6_000020" "g.42525912C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "883G>C (spl)" "reference haplotype CYP2D6*11; no activity" "Germline" "" "" "0" "" "" "g.42129910C>G" "" "pathogenic" "" "0000060646" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*11" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000060647" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*11" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000060648" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*11\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000060649" "1" "99" "22" "42526670" "42526670" "subst" "4.97121E-5" "00006" "CYP2D6_000021" "g.42526670C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "124G>A (G42R)" "reference haplotype CYP2D6*12; no activity" "Germline" "" "rs5030862" "0" "" "" "g.42130668C>T" "" "pathogenic" "" "0000060650" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*12" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000060651" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*12" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000060652" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*12\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000060653" "1" "99" "22" "42525772" "42525772" "subst" "0.013838" "00006" "CYP2D6_000022" "g.42525772G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1023C>T (T107I)" "reference haplotype CYP2D6*17; substrate specific decreased activity" "Germline" "" "rs28371706" "0" "" "" "g.42129770G>A" "" "pathogenic" "" "0000060654" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*17" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000060655" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*17" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000060656" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*17\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000060657" "1" "99" "22" "42525134" "42525134" "subst" "0.00667974" "00006" "CYP2D6_000169" "g.42525134C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1659G>A" "reference haplotype CYP2D6*29; decreased activity" "Germline" "-" "" "0" "" "" "g.42129132C>T" "" "pathogenic" "" "0000060658" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*29" "Germline" "-" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000060659" "1" "50" "22" "42523610" "42523610" "subst" "0.00647036" "00006" "CYP2D6_000024" "g.42523610C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3183G>A" "reference haplotype CYP2D6*29" "Germline" "-" "rs59421388" "0" "" "" "g.42127608C>T" "" "VUS" "" "0000060660" "1" "30" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*29\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "-" "" "0" "" "" "" "" "likely benign" "" "0000061081" "1" "10" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*41" "Germline" "-" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000061082" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*41" "Germline" "-" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000061083" "1" "99" "22" "42523805" "42523805" "subst" "0.0804508" "00006" "CYP2D6_000025" "g.42523805C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2988G>A (spl)" "reference haplotype CYP2D6*41; decreased activity (altered splicing, reduced protein levels)" "Germline" "-" "rs28371725" "0" "" "" "g.42127803C>T" "" "pathogenic" "" "0000061084" "1" "30" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*41\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "-" "rs1135840" "0" "" "" "" "" "likely benign" "" "0000061085" "1" "11" "22" "42528028" "42528028" "" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*41; NOTE reference sequence is not CYP2D6*1" "Germline" "-" "" "0" "" "" "" "" "benign" "" "0000061086" "1" "11" "22" "42527533" "42527533" "" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*41; NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "yes" "rs28624811" "0" "" "" "" "" "benign" "" "0000061087" "1" "11" "22" "42527471" "42527471" "" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*41; NOTE reference sequence is not CYP2D6*1" "Germline" "-" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000061091" "1" "77" "22" "42525077" "42525077" "subst" "0.00318442" "00006" "CYP2D6_000030" "g.42525077C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1716G>A (E155K)" "reference haplotype CYP2D6*45; slightly reduced activity" "Germline" "-" "rs28371710" "0" "" "" "g.42129075C>T" "" "likely pathogenic" "" "0000061092" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*46" "Germline" "-" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000061093" "1" "30" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*46\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "-" "rs1135840" "0" "" "" "" "" "likely benign" "" "0000061094" "1" "77" "22" "42525077" "42525077" "subst" "0.00318442" "00006" "CYP2D6_000030" "g.42525077C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1716G>A (E155K)" "reference haplotype CYP2D6*46; slightly reduced activity" "Germline" "yes" "rs28371710" "0" "" "" "g.42129075C>T" "" "likely pathogenic" "" "0000061095" "1" "33" "22" "42526717" "42526717" "subst" "0.00217384" "00006" "CYP2D6_000031" "g.42526717C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "77G>A (R26H)" "reference haplotype CYP2D6*46" "Germline" "" "rs28371696" "0" "" "" "g.42130715C>T" "" "likely benign" "" "0000062769" "1" "10" "22" "42523003" "42523003" "subst" "0" "01164" "CYP2D6_000035" "g.42523003G>A" "" "" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "" "" "benign" "" "0000062770" "1" "10" "22" "42523558" "42523558" "subst" "0" "01164" "CYP2D6_000032" "g.42523558T>C" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42127556T>C" "" "benign" "" "0000062771" "1" "90" "22" "42524178" "42524180" "del" "0" "01164" "CYP2D6_000014" "g.42524178_42524180del" "" "" "" "" "c.841_843delAAG(=c.2615_2617delAAG); CYP2D6*9-Allel" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "pathogenic" "" "0000062772" "1" "90" "22" "42526694" "42526694" "subst" "0.206804" "01164" "CYP2D6_000009" "g.42526694G>A" "" "" "" "" "CYP2D6*4" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000062773" "1" "59" "22" "42523805" "42523805" "subst" "0.0804508" "01164" "CYP2D6_000025" "g.42523805C>T" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "VUS" "" "0000062774" "1" "90" "22" "42524947" "42524947" "subst" "0.138444" "01164" "CYP2D6_000004" "g.42524947C>T" "" "" "" "" "CYP2D6*4; in combination with c.100C>T; p.Pro34Ser" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000062775" "1" "10" "22" "42523567" "42523567" "subst" "0.00109703" "01164" "CYP2D6_000033" "g.42523567T>C" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42127565T>C" "" "benign" "" "0000062776" "1" "10" "22" "42522669" "42522669" "subst" "0.00010518" "01164" "CYP2D6_000034" "g.42522669C>G" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42126667C>G" "" "benign" "" "0000073966" "1" "11" "22" "42522965" "42522965" "subst" "0.00439072" "00006" "CYP2D6_000036" "g.42522965C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3828G>A" "reference haplotype CYP2D6*1B ; XbaI haplotype 29kb" "Germline" "yes" "rs28371732" "0" "" "" "g.42126963C>T" "" "benign" "" "0000073967" "1" "11" "22" "42524815" "42524815" "subst" "0.00142576" "00006" "CYP2D6_000037" "g.42524815G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1978C>T" "reference haplotype CYP2D6*1C" "Germline" "yes" "rs150163869" "0" "" "" "g.42128813G>A" "" "benign" "" "0000073968" "1" "11" "22" "42524218" "42524218" "subst" "0.00765363" "00006" "CYP2D6_000038" "g.42524218G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2575C>A" "reference haplotype CYP2D6*1D" "Germline" "yes" "rs28371718" "0" "" "" "g.42128216G>T" "" "benign" "" "0000073970" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2A" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073971" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2B" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073972" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2C" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073973" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2E" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073974" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2F" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073975" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2G" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073976" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2H" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073977" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2XN" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073978" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*59 (*2J)" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073979" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2K" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073980" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B)" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073981" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T" "reference haplotype CYP2D6*2M" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000073982" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073983" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2B\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073984" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2C\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073985" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2E\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073986" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2F\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073987" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2G\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073988" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2H\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073989" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2XN\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073990" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*59 (*2J)\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073991" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2K\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073992" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B)\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073993" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*2M\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000073994" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2A" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000073995" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2B" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000073996" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2C" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000073997" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2E" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000073998" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2F" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000073999" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2G" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074000" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2H" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074001" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2XN" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074002" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*59 (*2J)" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074003" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2K" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074004" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B)" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074005" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*2M" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074006" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*2B" "Germline" "yes" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000074007" "1" "11" "22" "42524323" "42524323" "subst" "0.00661735" "00006" "CYP2D6_000041" "g.42524323A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2470T>C" "reference haplotype CYP2D6*2C" "Germline" "yes" "rs17002852" "0" "" "" "g.42128321A>G" "" "benign" "" "0000074008" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*2E" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074009" "1" "11" "22" "42525069" "42525069" "subst" "0.000674263" "00006" "CYP2D6_000042" "g.42525069G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1724C>T" "reference haplotype CYP2D6*2F" "Germline" "yes" "rs74962936" "0" "" "" "g.42129067G>A" "" "benign" "" "0000074010" "1" "11" "22" "42524218" "42524218" "subst" "0.00765363" "00006" "CYP2D6_000038" "g.42524218G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2575C>A" "reference haplotype CYP2D6*2G" "Germline" "yes" "rs28371718" "0" "" "" "g.42128216G>T" "" "benign" "" "0000074011" "1" "11" "22" "42524323" "42524323" "subst" "0.00661735" "00006" "CYP2D6_000041" "g.42524323A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2470T>C" "reference haplotype CYP2D6*2G" "Germline" "yes" "rs17002852" "0" "" "" "g.42128321A>G" "" "benign" "" "0000074012" "1" "11" "22" "42524313" "42524313" "subst" "0" "00006" "CYP2D6_000043" "g.42524313G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2480C>T" "reference haplotype CYP2D6*2H" "Germline" "yes" "" "0" "" "" "g.42128311G>A" "" "benign" "" "0000074013" "1" "11" "22" "42522678" "42522678" "subst" "0.00122349" "00006" "CYP2D6_000044" "g.42522678G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4115C>T" "reference haplotype CYP2D6*2K" "Germline" "yes" "rs150445731" "0" "" "" "g.42126676G>A" "" "benign" "" "0000074014" "1" "99" "22" "42523854" "42523854" "subst" "0.00291774" "00006" "CYP2D6_000045" "g.42523854C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2939G>A" "reference haplotype CYP2D6*59 (*2J); reduced mRNA and protein expression (and enzyme activity)" "Germline" "yes" "rs79292917" "0" "" "" "g.42127852C>T" "" "pathogenic" "" "0000074015" "1" "11" "22" "42523854" "42523854" "subst" "0.00291774" "00006" "CYP2D6_000045" "g.42523854C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2291G>A" "reference haplotype CYP2D6*59 (*2J)" "Germline" "yes" "rs267608300" "0" "" "" "g.42127852C>T" "" "benign" "" "0000074124" "1" "99" "22" "" "" "" "" "00006" "CYP2D6_000000" "g.(?_42522576)_(42526793_?)[N]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*1XN (N = number of copies); NOTE borders of the duplication to be checked" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000074125" "1" "50" "22" "42528382" "42528382" "" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*2A; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000074126" "1" "50" "22" "42528028" "42528028" "" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*2A; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "" "0" "" "" "" "" "VUS" "" "0000074127" "1" "50" "22" "42527533" "42527533" "" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*2A; NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "yes" "rs28624811" "0" "" "" "" "" "VUS" "" "0000074128" "1" "11" "22" "42527471" "42527471" "" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*2A; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000074129" "1" "99" "22" "" "" "" "" "00006" "CYP2D6_000000" "g.(?_42522576)_(42526793_?)[N]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "N = 2, 3, 4, 5, 13" "reference haplotype CYP2D6*1XN (N = 2, 3, 4, 5 or 13 copies)" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000074131" "1" "11" "22" "42528028" "42528028" "" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B); NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "" "0" "" "" "" "" "benign" "" "0000074132" "1" "11" "22" "42527533" "42527533" "" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B); NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "yes" "rs28624811" "0" "" "" "" "" "benign" "" "0000074133" "1" "11" "22" "42526484" "42526484" "" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B); NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074134" "1" "11" "22" "42526049" "42526049" "" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B); NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074135" "1" "11" "22" "42525952" "42525952" "" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B); NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074136" "1" "11" "22" "42525280" "42525280" "subst" "0" "00006" "CYP2D6_000051" "g.42525280G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1513C>T" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B)" "Germline" "yes" "rs67497403" "0" "" "" "g.42129278G>A" "" "benign" "" "0000074137" "1" "11" "22" "42525036" "42525036" "subst" "0.000200913" "00006" "CYP2D6_000052" "g.42525036G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1757C>T" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B)" "Germline" "yes" "rs199849357" "0" "" "" "g.42129034G>A" "" "benign" "" "0000074138" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B); NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000074139" "1" "11" "22" "42523209" "42523209" "" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B); NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074140" "1" "11" "22" "42523003" "42523003" "" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B); NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074150" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "" "0" "" "" "" "" "benign" "" "0000074151" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "yes" "rs28624811" "0" "" "" "" "" "benign" "" "0000074152" "1" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000074153" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074154" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074155" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074156" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000074157" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074158" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*2M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074159" "1" "11" "22" "" "" "" "" "00006" "CYP2D6_000000" "g.42528030_42528056T[N]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1258_-1237 varA" "reference haplotype CYP2D6*2M" "Germline" "yes" "rs56358138" "0" "" "" "" "" "benign" "" "0000074160" "1" "11" "22" "42527548" "42527549" "del" "0" "00006" "CYP2D6_000055" "g.42527548_42527549del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-750_-749delGA" "reference haplotype CYP2D6*2M" "Germline" "yes" "rs536645539" "0" "" "" "g.42131546_42131547del" "" "benign" "" "0000074161" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*2M" "Germline" "yes" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000074164" "1" "99" "22" "42524244" "42524244" "del" "0.0123819" "00006" "CYP2D6_000016" "g.42524244del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2549delA (259fs)" "reference haplotype CYP2D6*3A (CYP2D6*3)" "Germline" "yes" "rs35742686" "0" "" "" "g.42128242del" "" "pathogenic" "" "0000074165" "1" "99" "22" "42524244" "42524244" "del" "0.0123819" "00006" "CYP2D6_000016" "g.42524244del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2549delA (259fs)" "reference haplotype CYP2D6*3B" "Germline" "yes" "rs35742686" "0" "" "" "g.42128242del" "" "pathogenic" "" "0000074166" "1" "55" "22" "42525044" "42525044" "subst" "0" "00006" "CYP2D6_000057" "g.42525044T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1749A>G" "reference haplotype CYP2D6*3B" "Germline" "no" "rs1135824" "0" "" "" "g.42129042T>C" "" "VUS" "" "0000074167" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4A" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074168" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4B" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074169" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4C" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074170" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4D" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074171" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4E" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074172" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4F" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074173" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4G" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074174" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4H" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074175" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4J" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074176" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4K" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074177" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4L" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074178" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4M" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074179" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4N" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074180" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4P" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074181" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4X2" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000074182" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4A" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074183" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4B" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074184" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4C" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074185" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4D" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074186" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4E" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074187" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4F" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074188" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4G" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074189" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4H" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074190" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4J" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074191" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4K" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074192" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4L" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074193" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4N" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074194" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*4P" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074196" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4A" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074197" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4B" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074198" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4F" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074199" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4G" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074200" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4H" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074201" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4J" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074202" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4M" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074203" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4N" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074204" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*4P" "Germline" "yes" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000074206" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4A" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074207" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4B" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074208" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4F" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074209" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4G" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074210" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4H" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074211" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4J" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074212" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4M" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074213" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4N" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074214" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R)" "reference haplotype CYP2D6*4P" "Germline" "yes" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000074216" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4A" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074217" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4B" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074218" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4F" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074219" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4G" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074220" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4H" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074221" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4J" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074222" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4M" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074223" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4N" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074224" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G" "reference haplotype CYP2D6*4P" "Germline" "yes" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074226" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4A" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074227" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4C" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074228" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4D" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074229" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4E" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074230" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4F" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074231" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4G" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074232" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4H" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074233" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4J" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074234" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4K" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074235" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4L" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074236" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4M" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074237" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4N" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074238" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*4P" "Germline" "yes" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074240" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074241" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4B\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074242" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4C\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074243" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4D\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074244" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4E\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074245" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4F\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074246" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4G\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074247" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4H\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074248" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4K\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074249" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4L\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074250" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4N\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074251" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*4P\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "VUS" "" "0000074253" "1" "50" "22" "42522906" "42522906" "subst" "0" "00006" "CYP2D6_000058" "g.42522906A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3887T>C" "reference haplotype CYP2D6*4C" "Germline" "no" "rs72549345" "0" "" "" "g.42126904A>G" "" "VUS" "" "0000074254" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*4D" "Germline" "no" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000074255" "1" "50" "22" "42524935" "42524935" "subst" "8.14086E-5" "00006" "CYP2D6_000059" "g.42524935G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1858C>T (R173C)" "reference haplotype CYP2D6*4F" "Germline" "no" "rs67780109" "0" "" "" "g.42128933G>A" "" "VUS" "" "0000074256" "1" "50" "22" "42523855" "42523855" "subst" "0.000207547" "00006" "CYP2D6_000060" "g.42523855G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2938C>T (P325L)" "reference haplotype CYP2D6*4G" "Germline" "no" "rs140513104" "0" "" "" "g.42127853G>A" "" "VUS" "" "0000074257" "1" "50" "22" "42522916" "42522916" "subst" "1.9758E-5" "00006" "CYP2D6_000061" "g.42522916C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3877G>C (E418Q)" "reference haplotype CYP2D6*4H" "Germline" "no" "" "0" "" "" "g.42126914C>G" "" "VUS" "" "0000074258" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*4K" "Germline" "no" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074259" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997G>C" "reference haplotype CYP2D6*4L" "Germline" "no" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000074260" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*4M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074261" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*4M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000074262" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*4M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "" "0" "" "" "" "" "benign" "" "0000074263" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*4M; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074264" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*4M" "Germline" "no" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000074265" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*4M" "Germline" "no" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000074266" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*4M" "Germline" "no" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000074267" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*4N\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "no" "rs28588594" "0" "" "" "" "" "VUS" "" "0000074268" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*4N" "Germline" "no" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000074269" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*4N" "Germline" "no" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000074270" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*4N" "Germline" "no" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000074271" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*4N" "Germline" "no" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000074272" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*4N; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074273" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*4N; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074274" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*4N; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "" "0" "" "" "" "" "benign" "" "0000074275" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*4N; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074276" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*4N; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000074277" "1" "50" "22" "42522624" "42522669" "" "0" "00006" "CYP2D6_000067" "g.42522624_42522669con42536337_42536382" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "CYP2D7 gene conversion exon 9" "reference haplotype CYP2D6*4N; gene conversion to CYP2D7 exon 9" "Germline" "" "" "0" "" "" "" "" "VUS" "" "0000074278" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*4P\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "no" "rs28588594" "0" "" "" "" "" "VUS" "" "0000074279" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*4P; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "" "0" "" "" "" "" "benign" "" "0000074280" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*4P" "Germline" "no" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000074281" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*4P; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074282" "1" "11" "22" "42526049" "42526049" "" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*4P; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074283" "1" "11" "22" "42525952" "42525952" "" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*4P; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074284" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*4P" "Germline" "no" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000074285" "1" "50" "22" "42524217" "42524217" "subst" "8.20264E-6" "00006" "CYP2D6_000069" "g.42524217G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2576C>T" "reference haplotype CYP2D6*4P" "Germline" "yes" "" "0" "" "" "g.42128215G>A" "" "VUS" "" "0000074286" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*4P; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000074287" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*4P" "Germline" "no" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000074288" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*4P" "Germline" "no" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000074289" "1" "11" "22" "42523358" "42523358" "subst" "0" "00006" "CYP2D6_000068" "g.42523358G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3435C>A" "reference haplotype CYP2D6*4P" "Germline" "no" "rs28371729" "0" "" "" "g.42127356G>T" "" "benign" "" "0000074296" "1" "99" "22" "42525086" "42525086" "del" "0.00791688" "00006" "CYP2D6_000017" "g.42525086del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1707delT (118fs)" "reference haplotype CYP2D6*6B; no activity" "Germline" "yes" "rs5030655" "0" "" "" "g.42129084del" "" "pathogenic" "" "0000074297" "1" "99" "22" "42525086" "42525086" "del" "0.00791688" "00006" "CYP2D6_000017" "g.42525086del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1707delT (118fs)" "reference haplotype CYP2D6*6C; no activity" "Germline" "yes" "rs5030655" "0" "" "" "g.42129084del" "" "pathogenic" "" "0000074298" "1" "99" "22" "42525086" "42525086" "del" "0.00791688" "00006" "CYP2D6_000017" "g.42525086del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1707delT (118fs)" "reference haplotype CYP2D6*6D; no activity" "Germline" "yes" "rs5030655" "0" "" "" "g.42129084del" "" "pathogenic" "" "0000074299" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*6C; no activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "no" "rs1135840" "0" "" "" "" "" "benign" "" "0000074300" "1" "50" "22" "42524817" "42524817" "subst" "0.00699896" "00006" "CYP2D6_000070" "g.42524817C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1976G>A" "reference haplotype CYP2D6*6B; no activity" "Germline" "no" "rs139779104" "0" "" "" "g.42128815C>T" "" "VUS" "" "0000074301" "1" "50" "22" "42524817" "42524817" "subst" "0.00699896" "00006" "CYP2D6_000070" "g.42524817C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1976G>A" "reference haplotype CYP2D6*6C; no activity" "Germline" "no" "rs139779104" "0" "" "" "g.42128815C>T" "" "VUS" "" "0000074302" "1" "50" "22" "42523505" "42523505" "subst" "0" "00006" "CYP2D6_000071" "g.42523505C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3288G>A" "reference haplotype CYP2D6*6D; no activity" "Germline" "" "rs150552908" "0" "" "" "g.42127503C>T" "" "VUS" "" "0000074303" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*10B\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "no" "rs28588594" "0" "" "" "" "" "VUS" "" "0000074304" "1" "11" "22" "" "" "" "" "00006" "CYP2D6_000000" "g.42528030_42528056T[N]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1258_-1237 varA" "reference haplotype CYP2D6*10B" "Germline" "yes" "rs56358138" "0" "" "" "" "" "benign" "" "0000074305" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*10B; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "" "0" "" "" "" "" "benign" "" "0000074306" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*10B" "Germline" "no" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000074307" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*10B" "Germline" "yes" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000074308" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*10B" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000074309" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*10B" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074310" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*10B\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000074311" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*10D" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000074312" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*10D" "Germline" "no" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000074313" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*10D" "Germline" "no" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074314" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*10D\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "no" "rs1135840" "0" "" "" "" "" "benign" "" "0000074315" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*14A" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074316" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*14A" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074317" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*14A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074319" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*14B" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074320" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*14B" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074321" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*14B\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074323" "1" "99" "22" "42526657" "42526657" "dup" "0" "00006" "CYP2D6_000073" "g.42526657dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "137_138insT (46fs)" "reference haplotype CYP2D6*15; no activity" "Germline" "yes" "rs774671100" "0" "" "" "g.42130655dup" "" "pathogenic" "" "0000074324" "1" "90" "22" "42522660" "42522668" "dup" "0" "00006" "CYP2D6_000074" "g.42522660_42522668dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4125_4133dupGTGCCCACT" "reference haplotype CYP2D6*18" "Germline" "yes" "rs765776661" "0" "" "" "g.42126658_42126666dup" "" "pathogenic" "" "0000074325" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*20A" "Germline" "no" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074326" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*20A" "Germline" "no" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074327" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*20A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "no" "rs1135840" "0" "" "" "" "" "benign" "" "0000074328" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*19A" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074329" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*19A" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074330" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*19A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074331" "1" "99" "22" "42524819" "42524819" "dup" "0" "00006" "CYP2D6_000076" "g.42524819dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1973_1974insG (211fs)" "reference haplotype CYP2D6*20A" "Germline" "yes" "rs72549354" "0" "" "" "g.42128817dup" "" "pathogenic" "" "0000074333" "1" "50" "22" "42526712" "42526712" "subst" "0.00230891" "00006" "CYP2D6_000077" "g.42526712G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "82C>T (R28C)" "reference haplotype CYP2D6*22" "Germline" "" "rs138100349" "0" "" "" "g.42130710G>A" "" "VUS" "" "0000074334" "1" "50" "22" "42525838" "42525838" "subst" "3.54805E-5" "00006" "CYP2D6_000078" "g.42525838G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "957C>T (A85V)" "reference haplotype CYP2D6*23" "Germline" "" "rs267608310" "0" "" "" "g.42129836G>A" "" "VUS" "" "0000074335" "1" "50" "22" "42523940" "42523940" "subst" "1.22007E-5" "00006" "CYP2D6_000079" "g.42523940T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2853A>C (I297L)" "reference haplotype CYP2D6*24" "Germline" "" "" "0" "" "" "g.42127938T>G" "" "VUS" "" "0000074336" "1" "50" "22" "42523595" "42523595" "subst" "0" "00006" "CYP2D6_000080" "g.42523595G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3198C>G (R343G)" "reference haplotype CYP2D6*25" "Germline" "" "rs267608295" "0" "" "" "g.42127593G>C" "" "VUS" "" "0000074337" "1" "50" "22" "42523516" "42523516" "subst" "0" "00006" "CYP2D6_000081" "g.42523516A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3277T>C" "reference haplotype CYP2D6*26" "Germline" "" "" "0" "" "" "g.42127514A>G" "" "VUS" "" "0000074338" "1" "50" "22" "42522940" "42522940" "subst" "0" "00006" "CYP2D6_000082" "g.42522940C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3853G>A (E410K)" "reference haplotype CYP2D6*27" "Germline" "" "rs769157652" "0" "" "" "g.42126938C>T" "" "VUS" "" "0000074339" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*28" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074340" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*28" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074341" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*28\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074342" "1" "50" "22" "42526775" "42526775" "subst" "0.00242346" "00006" "CYP2D6_000083" "g.42526775C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "19G>A (V7M)" "reference haplotype CYP2D6*28" "Germline" "" "rs72549358" "0" "" "" "g.42130773C>T" "" "VUS" "" "0000074343" "1" "50" "22" "42525089" "42525089" "subst" "0.00237944" "00006" "CYP2D6_000084" "g.42525089G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1704C>G (Q151E)" "reference haplotype CYP2D6*28" "Germline" "" "rs78482768" "0" "" "" "g.42129087G>C" "" "VUS" "" "0000074344" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*30" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074345" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*30" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074346" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*30\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074347" "1" "50" "22" "42524936" "42524944" "dup" "0" "00006" "CYP2D6_000085" "g.42524936_42524944dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1863_1864insTTTCGCCCC (174_175insFRP)" "reference haplotype CYP2D6*30" "Germline" "" "rs553846709" "0" "" "" "g.42128934_42128942dup" "" "VUS" "" "0000074352" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*32" "Germline" "no" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074353" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*32" "Germline" "no" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074354" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*32\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "no" "rs1135840" "0" "" "" "" "" "benign" "" "0000074355" "1" "50" "22" "42522940" "42522940" "subst" "0" "00006" "CYP2D6_000082" "g.42522940C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3853G>A (E410K)" "reference haplotype CYP2D6*32" "Germline" "" "rs769157652" "0" "" "" "g.42126938C>T" "" "VUS" "" "0000074356" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*35A" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074357" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*35A" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074358" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*35A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074359" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*35X2" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074360" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*35X2" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074361" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*35X2\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074362" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*39" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074364" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*39\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074365" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*37" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074366" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*37" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000074367" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*37\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074368" "1" "33" "22" "42524310" "42524310" "subst" "0.00800593" "00006" "CYP2D6_000086" "g.42524310C>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2483G>T (A237S)" "reference haplotype CYP2D6*33" "Germline" "yes" "rs28371717" "0" "" "" "g.42128308C>A" "" "likely benign" "" "0000074370" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*34" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074372" "1" "11" "22" "42528382" "42528382" "" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*35A; NOTE reference sequence is not CYP2D6*1" "Germline" "no" "rs1080985" "0" "" "" "g.42132375G>C" "" "benign" "" "0000074373" "1" "33" "22" "42526763" "42526763" "subst" "0.0381894" "00006" "CYP2D6_000087" "g.42526763C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "31G>A (V11M)" "reference haplotype CYP2D6*35A" "Germline" "" "rs769258" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000074374" "1" "33" "22" "42526763" "42526763" "subst" "0.0381894" "00006" "CYP2D6_000087" "g.42526763C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "31G>A (V11M)" "reference haplotype CYP2D6*35X2" "Germline" "" "rs769258" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000074375" "1" "99" "22" "42522576" "42526793" "" "0" "00006" "CYP2D6_000000" "g.(?_42522576)_(42526793_?)dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "CYP2D6 duplicated" "reference haplotype CYP2D6*35X2; gene duplicated" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000074376" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*37" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000074377" "1" "50" "22" "42524850" "42524850" "subst" "1.298E-5" "00006" "CYP2D6_000088" "g.42524850C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1943G>A (R201H)" "reference haplotype CYP2D6*37" "Germline" "yes" "rs72549355" "0" "" "" "g.42128848C>T" "" "VUS" "" "0000074378" "1" "99" "22" "42524205" "42524208" "del" "0" "00006" "CYP2D6_000089" "g.42524205_42524208del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2587_2590delGACT" "reference haplotype CYP2D6*38" "Germline" "yes" "rs72549351" "0" "" "" "g.42128203_42128206del" "" "pathogenic" "" "0000074379" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*40" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074380" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*40" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074381" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*40\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074382" "1" "50" "22" "42525772" "42525772" "subst" "0.013838" "00006" "CYP2D6_000022" "g.42525772G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1023C>T (T107I)" "reference haplotype CYP2D6*40" "Germline" "no" "rs28371706" "0" "" "" "g.42129770G>A" "" "VUS" "" "0000074383" "1" "99" "22" "42524930" "42524938" "" "0" "00006" "CYP2D6_000090" "g.42524930_42524938[3]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1863_1864insTTTCGCCCCx2 (174_175insFRPx2)" "reference haplotype CYP2D6*40; no activity" "Germline" "yes" "rs553846709" "0" "" "" "" "" "pathogenic" "" "0000074384" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*42" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074385" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*42" "Germline" "yes" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074386" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*42\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "yes" "rs1135840" "0" "" "" "" "" "benign" "" "0000074387" "1" "99" "22" "42523534" "42523535" "dup" "0" "00006" "CYP2D6_000091" "g.42523534_42523535dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3259_3260insGT (363fs)" "reference haplotype CYP2D6*42; no activity" "Germline" "yes" "rs72549346" "0" "" "" "g.42127532_42127533dup" "" "pathogenic" "" "0000074388" "1" "33" "22" "42526717" "42526717" "subst" "0.00217384" "00006" "CYP2D6_000031" "g.42526717C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "77G>A (R26H)" "reference haplotype CYP2D6*43" "Germline" "" "rs28371696" "0" "" "" "g.42130715C>T" "" "likely benign" "" "0000074389" "1" "50" "22" "42526712" "42526712" "subst" "0.00230891" "00006" "CYP2D6_000077" "g.42526712G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "82C>T (R28C)" "reference haplotype CYP2D6*44" "Germline" "no" "rs138100349" "0" "" "" "g.42130710G>A" "" "VUS" "" "0000074390" "1" "97" "22" "42523843" "42523843" "subst" "0" "00006" "CYP2D6_000092" "g.42523843C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2950G>C (spl)" "reference haplotype CYP2D6*44" "Germline" "yes" "" "0" "" "" "g.42127841C>G" "" "pathogenic" "" "0000074391" "2" "30" "22" "42526712" "42526712" "subst" "0.00230891" "00006" "CYP2D6_000077" "g.42526712G>A" "" "{PMID:Yamazaki 2003:15618746}" "" "" "" "Germline" "" "" "0" "" "" "g.42130710G>A" "" "likely benign" "" "0000074392" "2" "90" "22" "42523843" "42523843" "subst" "0" "00006" "CYP2D6_000092" "g.42523843C>G" "1/86 cases" "{PMID:Yamazaki 2003:15618746}" "" "2950G>C (spl)" "" "Germline" "" "" "0" "" "" "g.42127841C>G" "" "pathogenic" "" "0000074393" "1" "10" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Yamazaki 2003:15618746}" "" "CYP2D6*2" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074394" "1" "10" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Yamazaki 2003:15618746}" "" "CYP2D6*2" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "" "" "benign" "" "0000074395" "1" "30" "22" "42525823" "42525823" "subst" "0" "00006" "CYP2D6_000093" "g.42525823G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "972C>T (A90V)" "reference haplotype CYP2D6*48" "Germline" "yes" "rs267608309" "0" "" "" "g.42129821G>A" "" "likely benign" "" "0000074396" "1" "90" "22" "42525073" "42525073" "subst" "2.51722E-5" "00006" "CYP2D6_000094" "g.42525073T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1720A>C (E156A)" "reference haplotype CYP2D6*50" "Germline" "yes" "rs267608302" "0" "" "" "g.42129071T>G" "" "pathogenic" "" "0000074397" "1" "50" "22" "42522699" "42522699" "subst" "0" "00006" "CYP2D6_000095" "g.42522699G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4094C>A (F457L)" "reference haplotype CYP2D6*97" "Germline" "yes" "" "0" "" "" "g.42126697G>T" "" "VUS" "" "0000074398" "1" "90" "22" "42522898" "42522898" "subst" "0" "00006" "CYP2D6_000096" "g.42522898G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3895C>T (Q424X)" "reference haplotype CYP2D6*96" "Germline" "yes" "rs763964554" "0" "" "" "g.42126896G>A" "" "pathogenic" "" "0000074399" "1" "50" "22" "42524274" "42524274" "subst" "0" "00006" "CYP2D6_000097" "g.42524274T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2519A>C (T249P)" "reference haplotype CYP2D6*93" "Germline" "yes" "" "0" "" "" "g.42128272T>G" "" "VUS" "" "0000074400" "1" "99" "22" "42524798" "42524798" "del" "0" "00006" "CYP2D6_000098" "g.42524798del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1995delC (218fs)" "reference haplotype CYP2D6*92" "Germline" "yes" "" "0" "" "" "g.42128796del" "" "pathogenic" "" "0000074401" "1" "50" "22" "42525100" "42525100" "subst" "4.11225E-6" "00006" "CYP2D6_000099" "g.42525100T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1693A>G (K147R)" "reference haplotype CYP2D6*90" "Germline" "yes" "rs569229126" "0" "" "" "g.42129098T>C" "" "VUS" "" "0000074402" "1" "50" "22" "42525115" "42525115" "subst" "6.15996E-5" "00006" "CYP2D6_000100" "g.42525115A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1678T>C (L142S)" "reference haplotype CYP2D6*89" "Germline" "yes" "rs375135093" "0" "" "" "g.42129113A>G" "" "VUS" "" "0000074403" "1" "50" "22" "42524187" "42524187" "subst" "0.000940402" "00006" "CYP2D6_000193" "g.42524187C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2606G>A (E278K)" "reference haplotype CYP2D6*86" "Germline" "" "rs77913725" "0" "" "" "g.42128185C>T" "" "VUS" "" "0000074404" "1" "50" "22" "42524183" "42524183" "subst" "0.00234546" "00006" "CYP2D6_000101" "g.42524183A>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2610T>A (M279K)" "reference haplotype CYP2D6*86" "Germline" "" "rs1135828" "0" "" "" "g.42128181A>T" "" "VUS" "" "0000074405" "1" "50" "22" "42522748" "42522748" "subst" "7.81672E-5" "00006" "CYP2D6_000102" "g.42522748C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4045G>A (R441H)" "reference haplotype CYP2D6*75" "Germline" "yes" "rs532668079" "0" "" "" "g.42126746C>T" "" "VUS" "" "0000074406" "1" "30" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M)" "reference haplotype CYP2D6*74" "Germline" "" "rs28371703" "0" "" "" "g.42129819G>T" "" "likely benign" "" "0000074407" "1" "33" "22" "42523184" "42523184" "subst" "0" "00006" "CYP2D6_000103" "g.42523184C>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3609G>T" "reference haplotype CYP2D6*74" "Germline" "" "rs267608322" "0" "" "" "g.42127182C>A" "" "likely benign" "" "0000074408" "1" "99" "22" "42522749" "42522749" "subst" "0.000178924" "00006" "CYP2D6_000104" "g.42522749G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4044C>T (R441C)" "reference haplotype CYP2D6*62" "Germline" "" "rs730882171" "0" "" "" "g.42126747G>A" "" "pathogenic" "" "0000074409" "1" "99" "22" "42524905" "42524906" "ins" "0" "00006" "CYP2D6_000105" "g.42524905_42524906insTA" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1887insTA (S183X)" "reference haplotype CYP2D6*60" "Germline" "yes" "" "0" "" "" "g.42128903_42128904insTA" "" "pathogenic" "" "0000074410" "1" "33" "22" "42524490" "42524490" "subst" "0" "00006" "CYP2D6_000106" "g.42524490G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2303C>T" "reference haplotype CYP2D6*60" "Germline" "" "rs79738337" "0" "" "" "g.42128488G>A" "" "likely benign" "" "0000074412" "1" "11" "22" "42526524" "42526524" "subst" "0" "01334" "CYP2D6_000107" "g.42526524G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130522G>A" "" "benign" "" "0000074414" "1" "10" "22" "42525625" "42525625" "subst" "0" "01334" "CYP2D6_000108" "g.42525625C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129623C>T" "" "benign" "" "0000074415" "1" "10" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000074416" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000074417" "2" "10" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000074418" "2" "10" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000074419" "2" "30" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "likely benign" "" "0000074420" "2" "10" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074421" "2" "10" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074422" "2" "10" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000074423" "2" "99" "22" "42523805" "42523805" "subst" "0.0804508" "01334" "CYP2D6_000025" "g.42523805C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "pathogenic" "" "0000074424" "2" "10" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074425" "2" "10" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074426" "2" "10" "22" "42525952" "42525952" "" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074427" "2" "10" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074428" "2" "10" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074429" "2" "10" "22" "42526549" "42526549" "" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000074431" "2" "10" "22" "42526561" "42526562" "" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000074432" "2" "10" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000074433" "2" "10" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000074434" "2" "10" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000074435" "2" "10" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000074436" "2" "10" "22" "42527471" "42527471" "" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "benign" "" "0000074437" "2" "10" "22" "42527533" "42527533" "" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "benign" "" "0000074438" "2" "30" "22" "42528028" "42528028" "" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000074439" "2" "10" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000116" "g.42528030_42528056T[25]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTT" "" "Germline" "" "" "0" "" "" "g.42132047_42132049dup" "" "benign" "" "0000074440" "2" "10" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "benign" "" "0000074813" "1" "10" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000074814" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000074815" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000074816" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000074817" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000074818" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074819" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074820" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000074821" "2" "99" "22" "42523805" "42523805" "subst" "0.0804508" "01334" "CYP2D6_000025" "g.42523805C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127941G>A" "" "pathogenic" "" "0000074822" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074823" "2" "11" "22" "42525952" "42525952" "" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074824" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074825" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074826" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000074827" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000074828" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000074829" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000074830" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000074831" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000074832" "2" "33" "22" "42526763" "42526763" "subst" "0.0381894" "01334" "CYP2D6_000087" "g.42526763C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000074833" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000074834" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000074835" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000074836" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000074837" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000074838" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000074857" "1" "11" "22" "0" "0" "" "0" "01334" "CYP2D6_000000" "g.=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000074858" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000074859" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000074860" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000074861" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000074862" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074863" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074864" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000074865" "2" "99" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "pathogenic" "" "0000074866" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074867" "2" "11" "22" "42525952" "42525952" "" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074868" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074869" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074870" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000074871" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000074872" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000074873" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000074874" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000074875" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000074876" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000074877" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000074878" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000074879" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000074880" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000074881" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000074882" "1" "11" "22" "42525625" "42525625" "subst" "0" "01334" "CYP2D6_000108" "g.42525625C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129623C>T" "" "benign" "" "0000074883" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000074884" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000074885" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000074886" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000074887" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074888" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074889" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000074890" "2" "30" "22" "42523613" "42523613" "subst" "0.00458212" "01334" "CYP2D6_000147" "g.42523613C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127611C>T" "" "likely benign" "" "0000074891" "2" "99" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "pathogenic" "" "0000074892" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074893" "2" "11" "22" "42525952" "42525952" "" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074894" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074895" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074896" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000074897" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000074898" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000074899" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000074900" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000074901" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000074902" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000074903" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000074904" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000074905" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000074906" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000074907" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000074908" "1" "11" "22" "42522965" "42522965" "subst" "0.00439072" "01334" "CYP2D6_000036" "g.42522965C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126963C>T" "" "benign" "" "0000074909" "1" "10" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000074910" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000074911" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000074912" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000074913" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000074914" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074915" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074916" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000074917" "2" "99" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "pathogenic" "" "0000074918" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074919" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074920" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074921" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074922" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000074923" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000074924" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000074925" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000074926" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000074927" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000074928" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000074929" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000074930" "2" "30" "22" "42528028" "42528028" "" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000074931" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000074932" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000074933" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000074934" "1" "11" "22" "42525625" "42525625" "subst" "0" "01334" "CYP2D6_000108" "g.42525625C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129623C>T" "" "benign" "" "0000074935" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000074936" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000074937" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000074938" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000074939" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074940" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074941" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000074942" "2" "99" "22" "42523805" "42523805" "subst" "0.0804508" "01334" "CYP2D6_000025" "g.42523805C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "pathogenic" "" "0000074943" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074944" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074945" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074946" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074947" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074948" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000074949" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000074950" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000074951" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000074952" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000074953" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000074954" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000074955" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000074956" "2" "10" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000116" "g.42528030_42528056T[25]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTT" "" "Germline" "" "" "0" "" "" "g.42132047_42132049dup" "" "benign" "" "0000074957" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000074958" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000074959" "1" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000112" "g.42528030_42528056T[20]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028delTT" "" "Germline" "" "" "0" "" "" "g.42132048_42132049del" "" "likely benign" "" "0000074981" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000114" "g.42528030_42528056T[23]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049dup" "" "likely benign" "" "0000074985" "1" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000112" "g.42528030_42528056T[20]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028delTT" "" "Germline" "" "" "0" "" "" "g.42132048_42132049del" "" "likely benign" "" "0000074986" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000074987" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000074988" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000074989" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000074990" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000074991" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000074992" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000074993" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000074994" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000074995" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000074996" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000074997" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000074998" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000074999" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000075000" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000075001" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000075002" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000075003" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000075004" "2" "30" "22" "42527116" "42527116" "subst" "0" "01334" "CYP2D6_000157" "g.42527116A>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131114A>G" "" "likely benign" "" "0000075005" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000075006" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000075007" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000075008" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000075009" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000075010" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000075047" "1" "11" "22" "42522392" "42522392" "subst" "0" "01334" "CYP2D6_000064" "g.42522392G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126390G>A" "" "benign" "" "0000075048" "1" "11" "22" "42523211" "42523211" "subst" "0" "01334" "CYP2D6_000063" "g.42523211T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127209T>C" "" "benign" "" "0000075049" "1" "11" "22" "42523358" "42523358" "subst" "0" "01334" "CYP2D6_000068" "g.42523358G>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127356G>T" "" "benign" "" "0000075050" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "01334" "CYP2D6_000007" "g.42525798G>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129796G>C" "" "benign" "" "0000075051" "1" "30" "22" "42525811" "42525811" "subst" "0.0973452" "01334" "CYP2D6_000002" "g.42525811T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129809T>C" "" "likely benign" "" "0000075052" "1" "30" "22" "42525821" "42525821" "subst" "0.0915689" "01334" "CYP2D6_000003" "g.42525821G>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129819G>T" "" "likely benign" "" "0000075053" "1" "30" "22" "42527793" "42527793" "subst" "0" "01334" "CYP2D6_000066" "g.42527793C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131791C>T" "" "likely benign" "" "0000075054" "1" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000114" "g.42528030_42528056T[23]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049dup" "" "likely benign" "" "0000075055" "1" "30" "22" "42528219" "42528219" "subst" "0" "01334" "CYP2D6_000065" "g.42528219G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132217G>A" "" "likely benign" "" "0000075056" "2" "33" "22" "42526763" "42526763" "subst" "0.0381894" "01334" "CYP2D6_000087" "g.42526763C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000075057" "1" "55" "22" "42526694" "42526694" "subst" "0.206804" "01334" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000075058" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000075059" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000075060" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000075061" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000075062" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075063" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000075064" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000075065" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000075066" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000075067" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000075068" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000075069" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000075070" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000075071" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000075072" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000075073" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000075074" "3" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000075075" "3" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000075076" "3" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000075077" "3" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075078" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000075079" "3" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000075080" "3" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000075081" "3" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000075082" "2" "99" "22" "42524947" "42524947" "subst" "0.138444" "01334" "CYP2D6_000004" "g.42524947C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000075083" "1" "11" "22" "42522392" "42522392" "subst" "0" "01334" "CYP2D6_000064" "g.42522392G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126390G>A" "" "benign" "" "0000075084" "1" "11" "22" "42523211" "42523211" "subst" "0" "01334" "CYP2D6_000063" "g.42523211T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127209T>C" "" "benign" "" "0000075085" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "01334" "CYP2D6_000007" "g.42525798G>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129796G>C" "" "benign" "" "0000075086" "1" "30" "22" "42525811" "42525811" "subst" "0.0973452" "01334" "CYP2D6_000002" "g.42525811T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129809T>C" "" "likely benign" "" "0000075087" "1" "30" "22" "42525821" "42525821" "subst" "0.0915689" "01334" "CYP2D6_000003" "g.42525821G>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129819G>T" "" "likely benign" "" "0000075088" "1" "30" "22" "42527793" "42527793" "subst" "0" "01334" "CYP2D6_000066" "g.42527793C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131791C>T" "" "likely benign" "" "0000075089" "1" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000114" "g.42528030_42528056T[23]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049dup" "" "likely benign" "" "0000075090" "1" "30" "22" "42528219" "42528219" "subst" "0" "01334" "CYP2D6_000065" "g.42528219G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132217G>A" "" "likely benign" "" "0000075091" "1" "55" "22" "42526694" "42526694" "subst" "0.206804" "01334" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000075092" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000075093" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000075094" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000075095" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000075096" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075097" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000075098" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000075099" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000075100" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000075101" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000075102" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000075103" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000075104" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000075105" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000118" "g.42528030_42528056T[27]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTTT" "" "Germline" "" "" "0" "" "" "g.42132045_42132049dup" "" "likely benign" "" "0000075106" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000075107" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000075108" "3" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000075109" "3" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000075110" "3" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000075111" "3" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075112" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000075113" "3" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000075114" "3" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000075115" "3" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000075116" "2" "99" "22" "42524947" "42524947" "subst" "0.138444" "01334" "CYP2D6_000004" "g.42524947C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000075117" "1" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000115" "g.42528030_42528056T[24]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTT" "" "Germline" "" "" "0" "" "" "g.42132048_42132049dup" "" "likely benign" "" "0000075118" "1" "99" "22" "42523805" "42523805" "subst" "0.0804508" "01334" "CYP2D6_000025" "g.42523805C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "pathogenic" "" "0000075119" "2" "30" "22" "42527116" "42527116" "subst" "0" "01334" "CYP2D6_000157" "g.42527116A>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131114A>G" "" "likely benign" "" "0000075120" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000118" "g.42528030_42528056T[27]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTTT" "" "Germline" "" "" "0" "" "" "g.42132045_42132049dup" "" "likely benign" "" "0000075121" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000075122" "3" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000075123" "3" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000075124" "3" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000075125" "3" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000075126" "3" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000075127" "3" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000075128" "3" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000075129" "3" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075130" "3" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075131" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000075132" "3" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000075133" "3" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000075134" "3" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000075135" "3" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000075136" "3" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000075137" "3" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000075138" "3" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000075139" "3" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000075140" "3" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000075141" "3" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000075142" "3" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000075143" "3" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000075144" "3" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000075145" "3" "11" "22" "42522392" "42522392" "subst" "0" "01334" "CYP2D6_000064" "g.42522392G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42126390G>A" "" "benign" "" "0000075146" "3" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000075147" "3" "11" "22" "42523211" "42523211" "subst" "0" "01334" "CYP2D6_000063" "g.42523211T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42127209T>C" "" "benign" "" "0000075148" "3" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000075149" "3" "99" "22" "42524947" "42524947" "subst" "0.138444" "01334" "CYP2D6_000004" "g.42524947C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000075151" "3" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075152" "3" "11" "22" "42525798" "42525798" "subst" "0.11339" "01334" "CYP2D6_000007" "g.42525798G>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42129796G>C" "" "benign" "" "0000075153" "3" "30" "22" "42525811" "42525811" "subst" "0.0973452" "01334" "CYP2D6_000002" "g.42525811T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42129809T>C" "" "likely benign" "" "0000075154" "3" "30" "22" "42525821" "42525821" "subst" "0.0915689" "01334" "CYP2D6_000003" "g.42525821G>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42129819G>T" "" "likely benign" "" "0000075155" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000075156" "3" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000075157" "3" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000075158" "3" "55" "22" "42526694" "42526694" "subst" "0.206804" "01334" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000075159" "3" "30" "22" "42527793" "42527793" "subst" "0" "01334" "CYP2D6_000066" "g.42527793C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42131791C>T" "" "likely benign" "" "0000075160" "3" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000075162" "3" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000114" "g.42528030_42528056T[23]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)" "Germline" "" "" "0" "" "" "g.42132049dup" "" "likely benign" "" "0000075164" "3" "30" "22" "42528219" "42528219" "subst" "0" "01334" "CYP2D6_000065" "g.42528219G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "other alelle *68 like (JF307779.1)\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132217G>A" "" "likely benign" "" "0000075362" "1" "11" "22" "42526545" "42526545" "subst" "0" "00006" "CYP2D6_000119" "g.42526545A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1869T>C" "reference haplotype CYP2D6*1E" "Germline" "" "" "0" "" "" "g.42130543A>G" "" "benign" "" "0000075363" "1" "99" "22" "42524947" "42524947" "subst" "0.138444" "00006" "CYP2D6_000004" "g.42524947C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1846G>A (spl)" "reference haplotype CYP2D6*4" "Germline" "yes" "rs3892097" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000075365" "1" "99" "22" "42525035" "42525035" "subst" "6.80151E-5" "00006" "CYP2D6_000019" "g.42525035C>A" "" "{PMID:Broly 1995:08530011}" "" "1758G>T" "no CYP2D6 activity" "Germline" "" "rs1058164" "0" "" "" "g.42129033C>A" "" "pathogenic" "" "0000075366" "1" "99" "22" "42524178" "42524180" "del" "0" "00006" "CYP2D6_000014" "g.42524178_42524180del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2615_2617delAAG duplicated" "reference haplotype CYP2D6*9X2" "Germline" "" "rs5030656" "0" "" "" "g.42128176_42128178del" "" "pathogenic" "" "0000075367" "1" "50" "22" "42522576" "42526793" "" "0" "00006" "CYP2D6_000000" "g.(?_42522576)_(42526793_?)dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2615_2617delAAG duplicated" "reference haplotype CYP2D6*9X2" "Germline" "" "" "0" "" "" "" "" "VUS" "" "0000075368" "1" "99" "22" "42525035" "42525035" "subst" "0.000960713" "00006" "CYP2D6_000072" "g.42525035C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1758G>A (G169R)" "reference haplotype CYP2D6*14; no activity (Gly169Arg)" "Germline" "" "rs5030865" "0" "" "" "g.42129033C>T" "" "pathogenic" "" "0000075370" "1" "99" "22" "42524253" "42524256" "del" "0" "00006" "CYP2D6_000120" "g.42524253_42524256del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2539_2542delAACT (255fs)" "reference haplotype CYP2D6*19A" "Germline" "yes" "rs72549353" "0" "" "" "g.42128251_42128254del" "" "pathogenic" "" "0000075371" "1" "99" "22" "42524253" "42524256" "del" "0" "00006" "CYP2D6_000120" "g.42524253_42524256del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2539_2542delAACT (255fs)" "reference haplotype CYP2D6*19" "Germline" "yes" "rs72549353" "0" "" "" "g.42128251_42128254del" "" "pathogenic" "" "0000075372" "1" "50" "22" "42524815" "42524815" "subst" "0.00142576" "00006" "CYP2D6_000037" "g.42524815G>A" "" "Reference Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1978C>T;1979T>C" "reference haplotype CYP2D6*20A" "Germline" "" "" "0" "" "" "g.42128813G>A" "" "VUS" "" "0000075373" "1" "99" "22" "42524819" "42524819" "dup" "0" "00006" "CYP2D6_000076" "g.42524819dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1973_1974insG" "reference haplotype CYP2D6*20" "Germline" "yes" "rs72549354" "0" "" "" "g.42128817dup" "" "pathogenic" "" "0000075374" "1" "33" "22" "42526763" "42526763" "subst" "0.0381894" "00006" "CYP2D6_000087" "g.42526763C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "31G>A (V11M)" "reference haplotype CYP2D6*35; normal activity" "Germline" "" "rs769258" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000075375" "3" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "1661G>C" "" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075376" "3" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "2850C>T (R296C)" "other alelle *68 like (JF307779.1)" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075377" "3" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000075378" "1" "50" "22" "42525772" "42525772" "subst" "0.013838" "00006" "CYP2D6_000022" "g.42525772G>A" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "1023C>T (T107I)" "" "Germline" "" "rs28371706" "0" "" "" "g.42129770G>A" "" "VUS" "" "0000075379" "1" "99" "22" "42524930" "42524938" "subst" "0" "00006" "CYP2D6_000090" "g.42524930_42524938[3]" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "1863_1864insTTTCGCCCCx2 (174_175insFRPx2)" "" "Germline" "" "rs553846709" "0" "" "" "" "" "pathogenic" "" "0000075383" "2" "99" "22" "42523534" "42523535" "dup" "0" "00006" "CYP2D6_000091" "g.42523534_42523535dup" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "3259_3260insGT (363fs)" "" "Germline" "" "rs72549346" "0" "" "" "g.42127532_42127533dup" "" "pathogenic" "" "0000075389" "2" "70" "22" "42523534" "42523535" "dup" "0" "00006" "CYP2D6_000091" "g.42523534_42523535dup" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "3259_3260insGT (363fs)" "" "Germline" "" "" "0" "" "" "g.42127532_42127533dup" "" "likely pathogenic" "" "0000075394" "1" "70" "22" "42525772" "42525772" "subst" "0.013838" "00006" "CYP2D6_000022" "g.42525772G>A" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "1023C>T (T107I)" "" "Germline" "" "rs28371706" "0" "" "" "g.42129770G>A" "" "likely pathogenic" "" "0000075395" "3" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "1661G>C" "" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075396" "3" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "2850C>T" "" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075397" "3" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "4180G>C" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000075398" "2" "99" "22" "42523534" "42523535" "dup" "0" "00006" "CYP2D6_000091" "g.42523534_42523535dup" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "3259_3260insGT (363fs)" "" "Germline" "" "rs72549346" "0" "" "" "g.42127532_42127533dup" "" "pathogenic" "" "0000075399" "1" "70" "22" "42525772" "42525772" "subst" "0.013838" "00006" "CYP2D6_000022" "g.42525772G>A" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "1023C>T (T107I)" "" "Germline" "" "rs28371706" "0" "" "" "g.42129770G>A" "" "likely pathogenic" "" "0000075400" "3" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "1661G>C" "" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075401" "3" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "2850C>T" "" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075402" "3" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Gaedigk 2003:12811367}, {DOI:Gaedigk 2003:10.1016/S0009-9236(03)00067-5}" "" "4180G>C" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000075403" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*47; negligible activity\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000075404" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*47; negligible activity" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000075405" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*47; negligible activity" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000075406" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*47; negligible activity" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000075407" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*47; negligible activity" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000075408" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*47; negligible activity" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075409" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*47; negligible activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000075410" "1" "50" "22" "42526721" "42526721" "subst" "0" "00006" "CYP2D6_000121" "g.42526721G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "73C>T" "reference haplotype CYP2D6*47; negligible activity" "Germline" "" "rs267608313" "0" "" "" "g.42130719G>A" "" "VUS" "" "0000075418" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*49; decreased activity\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000075419" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*49; decreased activity" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000075420" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*49; decreased activity" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000075421" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*49; decreased activity" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000075422" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*49; decreased activity" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000075423" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*49; decreased activity" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075424" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*49; decreased activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000075425" "1" "50" "22" "42525182" "42525182" "subst" "0.001645" "00006" "CYP2D6_000122" "g.42525182A>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1611T>A (F201I)" "reference haplotype CYP2D6*49; decreased activity" "Germline" "" "rs1135822" "0" "" "" "g.42129180A>T" "" "VUS" "" "0000075436" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*36 (formerly *10C); no activity\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000075437" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000075438" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000G>A" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000075439" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*36 (formerly CYP2D6*10C); no activity" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000075440" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000075441" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000075442" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000075443" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075444" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000075445" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000075446" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000075447" "1" "50" "22" "42522624" "42522669" "" "0" "00006" "CYP2D6_000067" "g.42522624_42522669con42536337_42536382" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "CYP2D7 gene conversion exon 9" "reference haplotype CYP2D6*36 (formerly *10C); no activity" "Germline" "" "" "0" "" "" "" "" "VUS" "" "0000075448" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*36 (formerly *10C); no activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000075449" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*36X2\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000075450" "1" "11" "22" "" "" "" "" "00006" "CYP2D6_000000" "g.42528030_42528056T[N]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1258_-1237 varA" "reference haplotype CYP2D6*36X2" "Germline" "" "rs56358138" "0" "" "" "" "" "benign" "" "0000075451" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*36X2" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000075452" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000G>A" "reference haplotype CYP2D6*36X2" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000075453" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*36X2" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000075454" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*36X2" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000075455" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*36X2" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075456" "1" "50" "22" "42522624" "42522669" "" "0" "00006" "CYP2D6_000067" "g.42522624_42522669con42536337_42536382" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "CYP2D7 gene conversion exon 9" "reference haplotype CYP2D6*36X2" "Germline" "" "" "0" "" "" "" "" "VUS" "" "0000075457" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*36X2\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000075458" "1" "99" "22" "42522575" "42526792" "" "0" "00006" "CYP2D6_000279" "g.(?_42522575)_(42526792_?)dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "CYP2D6 duplicated" "reference haplotype CYP2D6*36X2, found as duplicated CYP2D6*36 gen sequence or combined with CYP2D6*10" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000075459" "2" "10" "22" "42528563" "42528563" "subst" "0" "00006" "CYP2D6_000109" "g.42528563=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1770G>A" "reference haplotype CYP2D6*31" "Germline" "" "rs1080983" "0" "" "" "g.42132556=" "" "benign" "" "0000075460" "1" "50" "22" "42528382" "42528382" "" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*31; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000075461" "1" "11" "22" "42528028" "42528028" "" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*31; NOTE reference sequence is not CYP2D6*1" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000075462" "1" "11" "22" "42527533" "42527533" "" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*31; NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000075463" "1" "11" "22" "42527471" "42527471" "" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*31; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000075465" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*31" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000075466" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*31; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000075467" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*31" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000075468" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*31" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075469" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*31" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075470" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*31" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000075471" "1" "11" "22" "42523209" "42523209" "" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*31; NOTE reference sequence is not CYP2D6*1" "Germline" "yes" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000075472" "1" "11" "22" "42523003" "42523003" "" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*31; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000075473" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*31\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000075474" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*31" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000075475" "1" "99" "22" "42522751" "42522751" "subst" "0.000244137" "00006" "CYP2D6_000123" "g.42522751C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4042G>A" "reference haplotype CYP2D6*31; no activity" "Germline" "" "rs267608319" "0" "" "" "g.42126749C>T" "" "pathogenic" "" "0000075476" "1" "99" "22" "42524220" "42524220" "dup" "0" "00006" "CYP2D6_000124" "g.42524220dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2573_2574insC" "reference haplotype CYP2D6*21" "Germline" "yes" "rs72549352" "0" "" "" "g.42128218dup" "" "pathogenic" "" "0000075477" "1" "50" "22" "42528382" "42528382" "" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*21A; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000075478" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*21A\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000075479" "1" "11" "22" "" "" "" "" "00006" "CYP2D6_000000" "g.42528030_42528056T[N]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1258_-1237 varA" "reference haplotype CYP2D6*21A" "Germline" "" "rs56358138" "0" "" "" "" "" "benign" "" "0000075480" "1" "11" "22" "42528028" "42528028" "" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*21A; NOTE reference sequence is not CYP2D6*1" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000075481" "1" "11" "22" "42527533" "42527533" "" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*21A; NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000075482" "1" "11" "22" "42527471" "42527471" "" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*21A; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000075483" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*21A" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000075484" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*21A" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075485" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*21A" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075486" "1" "11" "22" "42523209" "42523209" "" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*21A; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000075487" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*21A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000075488" "1" "50" "22" "42527422" "42527422" "subst" "0" "00006" "CYP2D6_000125" "g.42527422T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-629A>G" "reference haplotype CYP2D6*21A" "Germline" "" "" "0" "" "" "g.42131420T>C" "" "VUS" "" "0000075489" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C" "reference haplotype CYP2D6*21A" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000075490" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G" "reference haplotype CYP2D6*21A" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000075491" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A" "reference haplotype CYP2D6*21A" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000075492" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C" "reference haplotype CYP2D6*21A" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000075493" "1" "99" "22" "42524220" "42524220" "dup" "0" "00006" "CYP2D6_000124" "g.42524220dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2573_2574insC" "reference haplotype CYP2D6*21A" "Germline" "yes" "rs72549352" "0" "" "" "g.42128218dup" "" "pathogenic" "" "0000075494" "1" "50" "22" "42528382" "42528382" "" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*21B; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000075495" "1" "11" "22" "42528028" "42528028" "" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*21B; NOTE reference sequence is not CYP2D6*2" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000075496" "1" "11" "22" "42527533" "42527533" "" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*21B; NOTE reference sequence is not CYP2D6*3\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000075497" "1" "11" "22" "42527471" "42527471" "" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*21B; NOTE reference sequence is not CYP2D6*4" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000075499" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*21B" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075500" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*21B" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075501" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*21B\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000075502" "1" "99" "22" "42524220" "42524220" "dup" "0" "00006" "CYP2D6_000124" "g.42524220dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2573_2574insC" "reference haplotype CYP2D6*21B" "Germline" "yes" "rs72549352" "0" "" "" "g.42128218dup" "" "pathogenic" "" "0000075503" "1" "50" "22" "42528382" "42528382" "" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*35B; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000075504" "1" "33" "22" "42526763" "42526763" "subst" "0.0381894" "00006" "CYP2D6_000087" "g.42526763C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "31G>A (V11M)" "reference haplotype CYP2D6*35B; normal activity" "Germline" "" "rs769258" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000075505" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*35B" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075506" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*35B" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000075507" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*35B\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000075508" "1" "50" "22" "42527147" "42527147" "subst" "0" "00006" "CYP2D6_000126" "g.42527147T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-354A>G" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs530422334" "0" "" "" "g.42131145T>C" "" "VUS" "" "0000075509" "1" "50" "22" "42527127" "42527127" "subst" "0" "00006" "CYP2D6_000127" "g.42527127C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-334G>C" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "" "0" "" "" "g.42131125C>G" "" "VUS" "" "0000075510" "1" "50" "22" "42527224" "42527224" "subst" "0" "00006" "CYP2D6_000128" "g.42527224G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-431C>T" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs566383351" "0" "" "" "g.42131222G>A" "" "VUS" "" "0000075511" "1" "50" "22" "42527124" "42527124" "subst" "0" "00006" "CYP2D6_000129" "g.42527124A>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-331T>G" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs34167214" "0" "" "" "g.42131122A>C" "" "VUS" "" "0000075512" "1" "50" "22" "42527120" "42527121" "inv" "0" "00006" "CYP2D6_000130" "g.42527120_42527121inv" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-328C>T -327A>G" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs35534760" "0" "" "" "g.42131118_42131119inv" "" "VUS" "" "0000075513" "1" "50" "22" "42527068" "42527069" "delins" "0" "00006" "CYP2D6_000131" "g.42527068_42527069delinsAA" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-276C>T -275C>T" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs34898711" "0" "" "" "g.42131066_42131067delinsAA" "" "VUS" "" "0000075514" "1" "50" "22" "42527113" "42527114" "delins" "0" "00006" "CYP2D6_000132" "g.42527113_42527114delinsCC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-321C>G -320A>G" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "" "0" "" "" "g.42131111_42131112delinsCC" "" "VUS" "" "0000075515" "1" "50" "22" "42527065" "42527065" "subst" "0" "00006" "CYP2D6_000133" "g.42527065G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-272C>T" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs35046171" "0" "" "" "g.42131063G>A" "" "VUS" "" "0000075516" "1" "50" "22" "42527060" "42527061" "delins" "0" "00006" "CYP2D6_000134" "g.42527060_42527061delinsGT" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-268G>A -267G>C" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs34894147" "0" "" "" "g.42131058_42131059delinsGT" "" "VUS" "" "0000075517" "1" "50" "22" "42527025" "42527025" "subst" "0" "00006" "CYP2D6_000135" "g.42527025C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-232G>C" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs35023634" "0" "" "" "g.42131023C>G" "" "VUS" "" "0000075518" "1" "50" "22" "42527018" "42527018" "subst" "0" "00006" "CYP2D6_000136" "g.42527018T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-225A>G" "reference haplotype CYP2D6*35B; CYP2D7 conversion upstream exon 1 (-225 to -431)" "Germline" "" "rs35481113" "0" "" "" "g.42131016T>C" "" "VUS" "" "0000075520" "1" "11" "22" "42528028" "42528028" "" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*46; NOTE reference sequence is not CYP2D6*2" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000075521" "1" "11" "22" "42527533" "42527533" "" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*46; NOTE reference sequence is not CYP2D6*2\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000075522" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*46" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000075523" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*46; NOTE reference sequence is not CYP2D6*2" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000075524" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*46" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000075525" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*46" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000075526" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*46" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000075527" "1" "11" "22" "42523209" "42523209" "" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*46; NOTE reference sequence is not CYP2D6*2" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000075528" "1" "11" "22" "42523003" "42523003" "" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*46; NOTE reference sequence is not CYP2D6*2" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000075529" "1" "50" "22" "42528336" "42528336" "subst" "0" "00006" "CYP2D6_000138" "g.42528336C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1543G>A" "reference haplotype CYP2D6*46\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs76210340" "0" "" "" "" "" "VUS" "" "0000075530" "1" "50" "22" "42528091" "42528091" "subst" "0" "00006" "CYP2D6_000047" "g.42528091C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1298G>A" "reference haplotype CYP2D6*46\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs59099247" "0" "" "" "" "" "VUS" "" "0000075531" "1" "33" "22" "42524218" "42524218" "subst" "0.00765363" "00006" "CYP2D6_000038" "g.42524218G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2575C>A" "reference haplotype CYP2D6*46" "Germline" "" "rs148769737" "0" "" "" "g.42128216G>T" "" "likely benign" "" "0000075532" "1" "33" "22" "42524132" "42524132" "subst" "0.00741985" "00006" "CYP2D6_000139" "g.42524132C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2661G>A" "reference haplotype CYP2D6*46" "Germline" "" "rs76015180" "0" "" "" "g.42128130C>T" "" "likely benign" "" "0000075533" "1" "33" "22" "42523302" "42523302" "subst" "0" "00006" "CYP2D6_000140" "g.42523302C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3491G>A" "reference haplotype CYP2D6*46" "Germline" "" "rs267608292" "0" "" "" "g.42127300C>T" "" "likely benign" "" "0000075534" "1" "33" "22" "42523539" "42523539" "subst" "0" "00006" "CYP2D6_000141" "g.42523539A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3254T>C" "reference haplotype CYP2D6*46" "Germline" "" "rs28371726" "0" "" "" "g.42127537A>G" "" "likely benign" "" "0000075535" "1" "33" "22" "42523763" "42523763" "subst" "0" "00006" "CYP2D6_000142" "g.42523763C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3030G>G/A" "reference haplotype CYP2D6*46 (both 3030G and 3030A)" "Germline" "" "rs267608291" "0" "" "" "g.42127761C>T" "" "likely benign" "" "0000081442" "1" "55" "22" "42523567" "42523567" "subst" "0.00109703" "00006" "CYP2D6_000033" "g.42523567T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3226A>G" "reference haplotype CYP2D6*108" "Germline" "" "rs61736517" "0" "" "" "g.42127565T>C" "" "VUS" "" "0000081443" "1" "55" "22" "42523558" "42523558" "subst" "0" "00006" "CYP2D6_000032" "g.42523558T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3235A>G" "reference haplotype CYP2D6*108" "Germline" "" "rs202102799" "0" "" "" "g.42127556T>C" "" "VUS" "" "0000096215" "0" "30" "22" "42526194" "42526194" "dup" "0" "00006" "CYP2D6_000170" "g.42526194dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "601delC" "reference haplotype CYP2D6*21A" "Germline" "" "" "0" "" "" "g.42130192dup" "" "likely benign" "" "0000096216" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*29" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096217" "0" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*35B" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000096218" "1" "11" "22" "42523003" "42523003" "" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*35B" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000096219" "1" "11" "22" "42523209" "42523209" "" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*35B" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000096220" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*35B" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096221" "1" "11" "22" "42525952" "42525952" "" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*35B" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096222" "1" "11" "22" "42526049" "42526049" "" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*35B" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000096223" "1" "11" "22" "42526484" "42526484" "" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*35B" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096224" "1" "55" "22" "42526931" "42526931" "subst" "0" "00006" "CYP2D6_000171" "g.42526931T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-138A>G" "reference haplotype CYP2D6*35B" "Germline" "" "rs267608272" "0" "" "" "g.42130929T>C" "" "VUS" "" "0000096225" "1" "30" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*35B\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "likely benign" "" "0000096226" "1" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*35B" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000096227" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*35B" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000096228" "1" "10" "22" "42528563" "42528563" "subst" "0" "00006" "CYP2D6_000109" "g.42528563=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1770G>A" "reference haplotype CYP2D6*35B" "Germline" "" "rs1080983" "0" "" "" "g.42132556=" "" "benign" "" "0000096235" "1" "55" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*94A" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000096241" "1" "50" "22" "42523612" "42523612" "subst" "0.000105787" "00006" "CYP2D6_000172" "g.42523612T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3181A>G" "reference haplotype CYP2D6*94A" "Germline" "" "rs748712690" "0" "" "" "g.42127610T>C" "" "VUS" "" "0000096243" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*94A" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096244" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*94A" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096245" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*94A" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000096246" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*94A" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096247" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*94A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096248" "1" "55" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*94B" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000096250" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*94B" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096251" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*94B" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000096252" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*94B" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096253" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*94B\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096254" "1" "50" "22" "42523612" "42523612" "subst" "0.000105787" "00006" "CYP2D6_000172" "g.42523612T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3181A>G" "reference haplotype CYP2D6*94B" "Germline" "" "rs748712690" "0" "" "" "g.42127610T>C" "" "VUS" "" "0000096255" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D94B" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096256" "1" "55" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*95" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000096258" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*95" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096259" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*95" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000096260" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*95" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096261" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*95\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096262" "0" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*95" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096263" "1" "50" "22" "42523459" "42523459" "subst" "0.000138426" "00006" "CYP2D6_000173" "g.42523459C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3334G>A (R388H)" "reference haplotype CYP2D6*95" "Germline" "" "rs77312092" "0" "" "" "g.42127457C>T" "" "VUS" "" "0000096264" "1" "55" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*87" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000096265" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*87" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096266" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*87" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096267" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*87" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000096268" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*87" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096269" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*87\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096270" "1" "50" "22" "42526780" "42526780" "subst" "1.60275E-5" "00006" "CYP2D6_000174" "g.42526780G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "14C>T (A5V)" "reference haplotype CYP2D6*87" "Germline" "" "rs773790593" "0" "" "" "g.42130778G>A" "" "VUS" "" "0000096271" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*88" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000096272" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*88" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096273" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*88" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096274" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C" "reference haplotype CYP2D6*88\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096275" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*88" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096276" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*88" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000096277" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*88" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000096278" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G" "reference haplotype CYP2D6*88" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000096279" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C" "reference haplotype CYP2D6*88" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000096280" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C" "reference haplotype CYP2D6*88" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000096281" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G" "reference haplotype CYP2D6*88" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000096282" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A" "reference haplotype CYP2D6*88" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000096283" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C" "reference haplotype CYP2D6*88" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000096284" "1" "50" "22" "42525781" "42525781" "subst" "0.000104769" "00006" "CYP2D6_000175" "g.42525781A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1014T>C (V104A)" "reference haplotype CYP2D6*88" "Germline" "" "rs76187628" "0" "" "" "g.42129779A>G" "" "VUS" "" "0000096285" "1" "70" "22" "42523805" "42523805" "subst" "0.0804508" "00006" "CYP2D6_000025" "g.42523805C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2988G>A (spl)" "reference haplotype CYP2D6*91" "Germline" "" "rs28371725" "0" "" "" "g.42127803C>T" "" "likely pathogenic" "" "0000096286" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*91" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000096287" "1" "50" "22" "42525058" "42525058" "subst" "0" "00006" "CYP2D6_000176" "g.42525058C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1735G>C (C161S)" "reference haplotype CYP2D6*91" "Germline" "" "" "0" "" "" "g.42129056C>G" "" "VUS" "" "0000096288" "1" "50" "22" "42528091" "42528091" "subst" "0" "00006" "CYP2D6_000047" "g.42528091C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1298G>A" "reference haplotype CYP2D6*85\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs59099247" "0" "" "" "" "" "VUS" "" "0000096289" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*85" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000096290" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*85\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000096291" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*85" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096292" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*85" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000096293" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*85" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096294" "1" "11" "22" "42525280" "42525280" "subst" "0" "00006" "CYP2D6_000051" "g.42525280G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1513C>T" "reference haplotype CYP2D6*85" "Germline" "" "rs67497403" "0" "" "" "g.42129278G>A" "" "benign" "" "0000096295" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*85" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096296" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*85" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000096297" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*85" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096298" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*85" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000096299" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*85" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000096300" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*85\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096301" "1" "50" "22" "42528538" "42528538" "subst" "0" "00006" "CYP2D6_000177" "g.42528538G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1740C>T" "reference haplotype CYP2D6*85" "Germline" "" "rs58188898" "0" "" "" "g.42132531G>A" "" "VUS" "" "0000096302" "1" "50" "22" "42526692" "42526692" "subst" "0.000366523" "00006" "CYP2D6_000178" "g.42526692T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "102A>G" "reference haplotype CYP2D6*85" "Germline" "" "rs151226748" "0" "" "" "g.42130690T>C" "" "VUS" "" "0000096303" "1" "50" "22" "42526188" "42526188" "subst" "0" "00006" "CYP2D6_000179" "g.42526188C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "607G>A" "reference haplotype CYP2D6*85" "Germline" "" "rs575159870" "0" "" "" "g.42130186C>T" "" "VUS" "" "0000096304" "1" "11" "22" "42524485" "42524485" "subst" "0" "00006" "CYP2D6_000180" "g.42524485C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2308G>A" "reference haplotype CYP2D6*85" "Germline" "" "rs188062577" "0" "" "" "g.42128483C>T" "" "benign" "" "0000096305" "1" "50" "22" "42522636" "42522636" "subst" "0" "00006" "CYP2D6_000181" "g.42522636A>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4157T>G (H478Q)" "reference haplotype CYP2D6*85" "Germline" "" "" "0" "" "" "g.42126634A>C" "" "VUS" "" "0000096306" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*83" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096307" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T); con ex9" "reference haplotype CYP2D6*83\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096308" "1" "11" "22" "42522669" "42522669" "subst" "0.00010518" "00006" "CYP2D6_000034" "g.42522669C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4124G>C; con ex9" "reference haplotype CYP2D6*83" "Germline" "" "rs1135832" "0" "" "" "g.42126667C>G" "" "benign" "" "0000096309" "1" "50" "22" "42522662" "42522663" "delins" "0" "00006" "CYP2D6_000182" "g.42522662_42522663delinsGC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4128C>G (P469A); con ex9" "reference haplotype CYP2D6*83" "Germline" "" "rs1135833" "0" "" "" "g.42126660_42126661delinsGC" "" "VUS" "" "0000096310" "1" "50" "22" "42522662" "42522662" "subst" "7.0729E-5" "00006" "CYP2D6_000183" "g.42522662T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4131A>G (T470A); con ex9" "reference haplotype CYP2D6*83" "Germline" "" "rs1135835" "0" "" "" "g.42126660T>C" "" "VUS" "" "0000096311" "1" "11" "22" "42522660" "42522660" "subst" "8.7255E-5" "00006" "CYP2D6_000184" "g.42522660A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4133T>C; con ex9" "reference haplotype CYP2D6*83" "Germline" "" "" "0" "" "" "g.42126658A>G" "" "benign" "" "0000096312" "1" "50" "22" "42522637" "42522638" "delins" "0" "00006" "CYP2D6_000185" "g.42522637_42522638delinsGA" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4155C>T;4156A>C (H478S); con ex9" "reference haplotype CYP2D6*83" "Germline" "" "" "0" "" "" "g.42126635_42126636delinsGA" "" "VUS" "" "0000096313" "1" "50" "22" "42522635" "42522635" "subst" "0" "00006" "CYP2D6_000186" "g.42522635C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4158G>C (G479R); con ex9" "reference haplotype CYP2D6*83" "Germline" "" "rs1135837" "0" "" "" "g.42126633C>G" "" "VUS" "" "0000096314" "1" "50" "22" "42522629" "42522629" "subst" "0" "00006" "CYP2D6_000187" "g.42522629A>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4164T>G (F481V); con ex9" "reference haplotype CYP2D6*83" "Germline" "" "" "0" "" "" "g.42126627A>C" "" "VUS" "" "0000096315" "1" "50" "22" "42522624" "42522627" "delins" "0" "00006" "CYP2D6_000188" "g.42522624_42522627delinsGCTG" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4166T>C;4167G>A;4168C>G;4169T>C (A482S); con ex9" "reference haplotype CYP2D6*83" "Germline" "" "" "0" "" "" "g.42126622_42126625delinsGCTG" "" "VUS" "" "0000096316" "1" "11" "22" "42522621" "42522621" "subst" "0" "00006" "CYP2D6_000189" "g.42522621G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4172C>T; con ex9" "reference haplotype CYP2D6*83" "Germline" "" "rs28371736" "0" "" "" "g.42126619G>A" "" "benign" "" "0000096317" "1" "11" "22" "42522600" "42522600" "subst" "0.000237399" "00006" "CYP2D6_000190" "g.42522600A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4193T>C; con ex9" "reference haplotype CYP2D6*83" "Germline" "" "rs61731577" "0" "" "" "g.42126598A>G" "" "benign" "" "0000096318" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*84" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000096319" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*84\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000096320" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*84" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096321" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*84" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000096322" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*84" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096323" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*84" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000096324" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*84" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096325" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*84" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000096326" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*84" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000096327" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*84\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096328" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*84" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000096329" "1" "33" "22" "42523302" "42523302" "subst" "0" "00006" "CYP2D6_000140" "g.42523302C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3491G>A" "reference haplotype CYP2D6*84" "Germline" "" "rs267608292" "0" "" "" "g.42127300C>T" "" "likely benign" "" "0000096330" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*84" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096331" "1" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*84" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000096332" "1" "11" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C" "reference haplotype CYP2D6*84" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000096333" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A" "reference haplotype CYP2D6*84" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000096334" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G" "reference haplotype CYP2D6*84" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000096335" "1" "11" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C" "reference haplotype CYP2D6*84" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000096336" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C" "reference haplotype CYP2D6*84" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000096337" "1" "50" "22" "42528538" "42528538" "subst" "0" "00006" "CYP2D6_000177" "g.42528538G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1740C>T" "reference haplotype CYP2D6*84" "Germline" "" "rs58188898" "0" "" "" "g.42132531G>A" "" "VUS" "" "0000096338" "1" "11" "22" "42526776" "42526776" "subst" "0.000166677" "00006" "CYP2D6_000191" "g.42526776C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "18G>A" "reference haplotype CYP2D6*84" "Germline" "" "rs148382141" "0" "" "" "g.42130774C>T" "" "benign" "" "0000096339" "1" "11" "22" "42526549" "42526549" "" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G" "reference haplotype CYP2D6*84" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000096340" "1" "50" "22" "42524219" "42524219" "subst" "0.000217438" "00006" "CYP2D6_000192" "g.42524219G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2574C>A (P267H)" "reference haplotype CYP2D6*84" "Germline" "" "rs148769737" "0" "" "" "g.42128217G>T" "" "VUS" "" "0000096355" "1" "50" "22" "42524187" "42524187" "subst" "0.000940402" "00006" "CYP2D6_000193" "g.42524187C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2606G>A (E278K)" "reference haplotype CYP2D6*81" "Germline" "" "rs77913725" "0" "" "" "g.42128185C>T" "" "VUS" "" "0000096356" "1" "50" "22" "42524183" "42524183" "subst" "0.00234546" "00006" "CYP2D6_000101" "g.42524183A>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2610T>A (M279K)" "reference haplotype CYP2D6*81" "Germline" "" "rs1135828" "0" "" "" "g.42128181A>T" "" "VUS" "" "0000096357" "1" "50" "22" "42525821" "42525821" "subst" "0.0915689" "00006" "CYP2D6_000003" "g.42525821G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "974C>A (L91M); con ex2" "reference haplotype CYP2D6*82" "Germline" "" "rs28371703" "0" "" "" "g.42129819G>T" "" "VUS" "" "0000096358" "1" "50" "22" "42525811" "42525811" "subst" "0.0973452" "00006" "CYP2D6_000002" "g.42525811T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "984A>G (H94R); con ex2" "reference haplotype CYP2D6*82" "Germline" "" "rs28371704" "0" "" "" "g.42129809T>C" "" "VUS" "" "0000096359" "1" "11" "22" "42525798" "42525798" "subst" "0.11339" "00006" "CYP2D6_000007" "g.42525798G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "997C>G; con ex2" "reference haplotype CYP2D6*82" "Germline" "" "rs28371705" "0" "" "" "g.42129796G>C" "" "benign" "" "0000096360" "1" "50" "22" "42525781" "42525781" "subst" "0.000104769" "00006" "CYP2D6_000175" "g.42525781A>G" "" "" "" "1014T>C (V104A); con ex2" "reference haplotype CYP2D6*82" "Germline" "" "rs76187628" "0" "" "" "g.42129779A>G" "" "VUS" "" "0000096361" "1" "50" "22" "42525772" "42525773" "delins" "0" "00006" "CYP2D6_000075" "g.42525772_42525773delinsTA" "" "" "" "1022A>T;1023C>A (T107Y); con ex2" "reference haplotype CYP2D6*82" "Germline" "" "" "0" "" "" "g.42129770_42129771delinsTA" "" "VUS" "" "0000096362" "1" "50" "22" "42525767" "42525767" "subst" "0.000315951" "00006" "CYP2D6_000039" "g.42525767T>C" "" "" "" "1028A>G (I109V); con ex2" "reference haplotype CYP2D6*82" "Germline" "" "rs78459009" "0" "" "" "g.42129765T>C" "" "VUS" "" "0000096363" "1" "50" "22" "42525759" "42525759" "subst" "0.000527496" "00006" "CYP2D6_000023" "g.42525759A>G" "" "" "" "1036T>C; con ex2" "reference haplotype CYP2D6*82" "Germline" "" "rs1135821" "0" "" "" "g.42129757A>G" "" "VUS" "" "0000096364" "1" "99" "22" "42524214" "42524214" "subst" "7.4422E-5" "00006" "CYP2D6_000194" "g.42524214G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2579C>T (R269X)" "reference haplotype CYP2D6*81" "Germline" "" "rs367543000" "0" "" "" "g.42128212G>A" "" "pathogenic" "" "0000096365" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*73\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000096366" "1" "11" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C; con in1" "reference haplotype CYP2D6*73" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000096367" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A; con in1" "reference haplotype CYP2D6*73" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000096368" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G; con in1" "reference haplotype CYP2D6*73" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000096369" "1" "11" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C; con in1" "reference haplotype CYP2D6*73" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000096370" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C; con in1" "reference haplotype CYP2D6*73" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000096371" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G; con in1" "reference haplotype CYP2D6*73" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000096372" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*73" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096373" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*73" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000096374" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*73" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096375" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*73" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096376" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*73" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000096377" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*73" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096378" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*73" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000096379" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*73" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000096380" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*73\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096381" "1" "50" "22" "42525782" "42525782" "subst" "0" "00006" "CYP2D6_000195" "g.42525782C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1013G>A (V104M)" "reference haplotype CYP2D6*73" "Germline" "" "rs267608308" "0" "" "" "g.42129780C>T" "" "VUS" "" "0000096382" "1" "11" "22" "42522258" "42522258" "dup" "0" "00006" "CYP2D6_000196" "g.42522258dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4535insT" "reference haplotype CYP2D6*73" "Germline" "" "rs540263157" "0" "" "" "g.42126256dup" "" "benign" "" "0000096383" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*72\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000096384" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*72" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000096385" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*72" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000096386" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*72" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000096387" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*72" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096388" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*72" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096389" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*72" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000096390" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*72" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096391" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*72" "Germline" "" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000096392" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*72" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096393" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*72" "Germline" "" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000096394" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*72\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096395" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*72" "Germline" "" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000096396" "1" "50" "22" "42523475" "42523475" "subst" "0.00041158" "00006" "CYP2D6_000197" "g.42523475C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3318G>A (E383K)" "reference haplotype CYP2D6*72" "Germline" "" "rs75386357" "0" "" "" "g.42127473C>T" "" "VUS" "" "0000096397" "1" "50" "22" "42528382" "42528382" "subst" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*71" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000096398" "1" "50" "22" "42526669" "42526669" "subst" "0.000231777" "00006" "CYP2D6_000198" "g.42526669C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "125G>A (G42E)" "reference haplotype CYP2D6*71" "Germline" "" "rs118203758" "0" "" "" "g.42130667C>T" "" "VUS" "" "0000096399" "1" "11" "22" "42525299" "42525299" "subst" "0" "00006" "CYP2D6_000199" "g.42525299A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1494T>C" "reference haplotype CYP2D6*71" "Germline" "" "rs267608306" "0" "" "" "g.42129297A>G" "" "benign" "" "0000096400" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*70" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096401" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*70" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096402" "1" "70" "22" "42525134" "42525134" "subst" "0.00667974" "00006" "CYP2D6_000169" "g.42525134C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1659G>A" "reference haplotype CYP2D6*70" "Germline" "" "rs61736512" "0" "" "" "g.42129132C>T" "" "likely pathogenic" "" "0000096403" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*70" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096404" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*70" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096405" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*70\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096406" "1" "50" "22" "42526969" "42526969" "subst" "0" "00006" "CYP2D6_000200" "g.42526969C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-176G>A" "reference haplotype CYP2D6*70" "Germline" "" "rs1080993" "0" "" "" "g.42130967C>T" "" "VUS" "" "0000096407" "1" "50" "22" "42525185" "42525185" "subst" "2.10924E-5" "00006" "CYP2D6_000201" "g.42525185C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1608G>A (V119M)" "reference haplotype CYP2D6*70" "Germline" "" "rs374616348" "0" "" "" "g.42129183C>T" "" "VUS" "" "0000096408" "1" "50" "22" "42523610" "42523610" "subst" "0.00647036" "00006" "CYP2D6_000024" "g.42523610C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3183G>A (V338M)" "reference haplotype CYP2D6*70" "Germline" "" "rs59421388" "0" "" "" "g.42127608C>T" "" "VUS" "" "0000096409" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*69\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000096410" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*69" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000096411" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*69" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000096412" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*69; no activitydear8LOV" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000096413" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*69" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000096414" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*69" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000096415" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*69" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000096416" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*69" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000096417" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*69" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000096418" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*69" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000096419" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*69" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000096420" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*69" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000096421" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*69\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "benign" "" "0000096422" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*69" "Germline" "" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000096423" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*69" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000096424" "1" "11" "22" "42525733" "42525733" "subst" "0.000194565" "00006" "CYP2D6_000202" "g.42525733T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1062A>G" "reference haplotype CYP2D6*69" "Germline" "" "rs267608289" "0" "" "" "g.42129731T>C" "" "benign" "" "0000096425" "1" "99" "22" "42523805" "42523805" "subst" "0.0804508" "00006" "CYP2D6_000025" "g.42523805C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2988G>A (spl)" "reference haplotype CYP2D6*69; decreased activity (altered splicing, reduced protein levels)" "Germline" "" "rs28371725" "0" "" "985+39G>A" "g.42127803C>T" "" "pathogenic" "" "0000118991" "1" "11" "22" "42525625" "42525625" "subst" "0" "01334" "CYP2D6_000108" "g.42525625C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129623C>T" "" "benign" "" "0000118992" "1" "10" "22" "42528030" "42528056" "del" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000118993" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000118994" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000118995" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000118996" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000118997" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000118998" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000118999" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119000" "2" "99" "22" "42523805" "42523805" "subst" "0.0804508" "01334" "CYP2D6_000025" "g.42523805C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "pathogenic" "" "0000119001" "2" "99" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "pathogenic" "" "0000119002" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119003" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119004" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119005" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119006" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119007" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119008" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119009" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119010" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119011" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119012" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000119013" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119014" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119015" "2" "10" "22" "42528030" "42528056" "subst" "0" "01334" "CYP2D6_000116" "g.42528030_42528056T[25]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTT" "" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000119016" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000119017" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119018" "1" "99" "22" "42524178" "42524180" "del" "0" "01334" "CYP2D6_000014" "g.42524178_42524180del" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42128174_42128176delCTT" "" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "pathogenic" "" "0000119019" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119020" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000119021" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119022" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119023" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119024" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119025" "2" "99" "22" "42523805" "42523805" "subst" "0.0804508" "01334" "CYP2D6_000025" "g.42523805C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "pathogenic" "" "0000119026" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119027" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119028" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119029" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119030" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119031" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119032" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119033" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119034" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119035" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119036" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119037" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000119038" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119039" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119040" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000115" "g.42528030_42528056T[24]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTT" "" "Germline" "" "" "0" "" "" "g.42132048_42132049dup" "" "likely benign" "" "0000119041" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000119042" "1" "10" "22" "42525625" "42525625" "subst" "0" "01334" "CYP2D6_000108" "g.42525625C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129623C>T" "" "benign" "" "0000119043" "1" "11" "22" "42528030" "42528056" "del" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000119044" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119045" "2" "11" "22" "42522392" "42522392" "subst" "0" "01334" "CYP2D6_000064" "g.42522392G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126390G>A" "" "benign" "" "0000119046" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119047" "2" "11" "22" "42523211" "42523211" "subst" "0" "01334" "CYP2D6_000063" "g.42523211T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119048" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119049" "2" "30" "22" "42524696" "42524696" "subst" "0" "01334" "CYP2D6_000062" "g.42524696T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128694T>C" "" "likely benign" "" "0000119050" "2" "99" "22" "42524947" "42524947" "subst" "0.138444" "01334" "CYP2D6_000004" "g.42524947C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000119051" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119052" "2" "11" "22" "42525798" "42525798" "subst" "0.11339" "01334" "CYP2D6_000007" "g.42525798G>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129796G>C" "" "benign" "" "0000119053" "2" "30" "22" "42525811" "42525811" "subst" "0.0973452" "01334" "CYP2D6_000002" "g.42525811T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129809T>C" "" "likely benign" "" "0000119054" "2" "30" "22" "42525821" "42525821" "subst" "0.0915689" "01334" "CYP2D6_000003" "g.42525821G>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129819G>T" "" "likely benign" "" "0000119055" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119056" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119057" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119058" "2" "55" "22" "42526694" "42526694" "subst" "0.206804" "01334" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000119059" "2" "30" "22" "42527793" "42527793" "subst" "0" "01334" "CYP2D6_000066" "g.42527793C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131791C>T" "" "likely benign" "" "0000119060" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119061" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000114" "g.42528030_42528056T[23]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049dup" "" "likely benign" "" "0000119062" "2" "30" "22" "42528219" "42528219" "subst" "0" "01334" "CYP2D6_000065" "g.42528219G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132217G>A" "" "likely benign" "" "0000119063" "1" "10" "22" "42525625" "42525625" "subst" "0" "01334" "CYP2D6_000108" "g.42525625C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129623C>T" "" "benign" "" "0000119064" "1" "30" "22" "42527896" "42527896" "del" "0" "01334" "CYP2D6_000203" "g.42527896del" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131894del" "" "likely benign" "" "0000119065" "1" "11" "22" "42528030" "42528056" "del" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000119066" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119067" "2" "11" "22" "42522392" "42522392" "subst" "0" "01334" "CYP2D6_000064" "g.42522392G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126390G>A" "" "benign" "" "0000119068" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119069" "2" "11" "22" "42523211" "42523211" "subst" "0" "01334" "CYP2D6_000063" "g.42523211T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119070" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119071" "2" "30" "22" "42524696" "42524696" "subst" "0" "01334" "CYP2D6_000062" "g.42524696T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128694T>C" "" "likely benign" "" "0000119072" "2" "99" "22" "42524947" "42524947" "subst" "0.138444" "01334" "CYP2D6_000004" "g.42524947C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000119073" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119074" "2" "11" "22" "42525798" "42525798" "subst" "0.11339" "01334" "CYP2D6_000007" "g.42525798G>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129796G>C" "" "benign" "" "0000119075" "2" "30" "22" "42525811" "42525811" "subst" "0.0973452" "01334" "CYP2D6_000002" "g.42525811T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129809T>C" "" "likely benign" "" "0000119076" "2" "30" "22" "42525821" "42525821" "subst" "0.0915689" "01334" "CYP2D6_000003" "g.42525821G>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129819G>T" "" "likely benign" "" "0000119077" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119078" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119079" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119080" "2" "55" "22" "42526694" "42526694" "subst" "0.206804" "01334" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000119081" "2" "30" "22" "42527793" "42527793" "subst" "0" "01334" "CYP2D6_000066" "g.42527793C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131791C>T" "" "likely benign" "" "0000119082" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119083" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000114" "g.42528030_42528056T[23]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049dup" "" "likely benign" "" "0000119084" "2" "30" "22" "42528219" "42528219" "subst" "0" "01334" "CYP2D6_000065" "g.42528219G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132217G>A" "" "likely benign" "" "0000119085" "3" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119086" "3" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119087" "3" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119088" "3" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119089" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119090" "3" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119091" "3" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119092" "3" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119093" "3" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000119094" "3" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119095" "3" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119096" "3" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119097" "3" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119098" "3" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119099" "3" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119100" "3" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119101" "3" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119102" "3" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119103" "3" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119104" "3" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000119105" "3" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119106" "3" "11" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "benign" "" "0000119107" "3" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000119108" "3" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000119109" "3" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119110" "3" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119111" "3" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119112" "3" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119113" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119114" "3" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119115" "3" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119116" "3" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119117" "3" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000119118" "3" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119119" "3" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119120" "3" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119121" "3" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119122" "3" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119123" "3" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119124" "3" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119125" "3" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119126" "3" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119127" "3" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119128" "3" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000119129" "3" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119130" "3" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000119131" "3" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000119132" "3" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000119135" "1" "10" "22" "42525625" "42525625" "subst" "0" "01334" "CYP2D6_000108" "g.42525625C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129623C>T" "" "benign" "" "0000119136" "1" "30" "22" "42527896" "42527896" "del" "0" "01334" "CYP2D6_000203" "g.42527896del" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131894del" "" "likely benign" "" "0000119137" "1" "10" "22" "42528030" "42528056" "del" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000119138" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119139" "2" "11" "22" "42522071" "42522071" "" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119140" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119141" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119142" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119143" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119144" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119145" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119146" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119147" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119148" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119149" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119150" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119151" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119152" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119153" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119154" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119155" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119156" "2" "30" "22" "42528030" "42528056" "dup" "0" "01334" "CYP2D6_000116" "g.42528030_42528056T[25]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTT" "" "Germline" "" "" "0" "" "" "g.42132047_42132049dup" "" "likely benign" "" "0000119157" "1" "50" "22" "42524817" "42524817" "subst" "0.00699896" "01334" "CYP2D6_000070" "g.42524817C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128815C>T" "" "VUS" "" "0000119158" "1" "99" "22" "42525086" "42525086" "del" "0.00791688" "01334" "CYP2D6_000017" "g.42525086del" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129084del" "" "pathogenic" "" "0000119159" "1" "10" "22" "42525547" "42525547" "subst" "0" "01334" "CYP2D6_000005" "g.42525547G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129545G>A" "" "benign" "" "0000119160" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119161" "2" "11" "22" "42522392" "42522392" "subst" "0" "01334" "CYP2D6_000064" "g.42522392G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126390G>A" "" "benign" "" "0000119162" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119163" "2" "11" "22" "42523211" "42523211" "subst" "0" "01334" "CYP2D6_000063" "g.42523211T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119164" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119165" "2" "30" "22" "42524696" "42524696" "subst" "0" "01334" "CYP2D6_000062" "g.42524696T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128694T>C" "" "likely benign" "" "0000119166" "2" "99" "22" "42524947" "42524947" "subst" "0.138444" "01334" "CYP2D6_000004" "g.42524947C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "pathogenic" "" "0000119167" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119168" "2" "11" "22" "42525798" "42525798" "subst" "0.11339" "01334" "CYP2D6_000007" "g.42525798G>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129796G>C" "" "benign" "" "0000119169" "2" "30" "22" "42525811" "42525811" "subst" "0.0973452" "01334" "CYP2D6_000002" "g.42525811T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129809T>C" "" "likely benign" "" "0000119170" "2" "30" "22" "42525821" "42525821" "subst" "0.0915689" "01334" "CYP2D6_000003" "g.42525821G>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129819G>T" "" "likely benign" "" "0000119171" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119172" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119173" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119174" "2" "50" "22" "42526694" "42526694" "subst" "0.206804" "01334" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000119175" "2" "30" "22" "42527793" "42527793" "subst" "0" "01334" "CYP2D6_000066" "g.42527793C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131791C>T" "" "likely benign" "" "0000119176" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119177" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000114" "g.42528030_42528056T[23]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049dup" "" "likely benign" "" "0000119178" "2" "30" "22" "42528219" "42528219" "subst" "0" "01334" "CYP2D6_000065" "g.42528219G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132217G>A" "" "likely benign" "" "0000119179" "1" "50" "22" "42527633" "42527633" "subst" "0" "01334" "CYP2D6_000208" "g.42527633A>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131631A>T" "" "VUS" "" "0000119180" "1" "99" "22" "42524178" "42524180" "del" "0" "01334" "CYP2D6_000014" "g.42524178_42524180del" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42128174_42128176delCTT" "" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "pathogenic" "" "0000119181" "1" "50" "22" "42527612" "42527612" "subst" "0" "01334" "CYP2D6_000207" "g.42527612G>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131610G>C" "" "VUS" "" "0000119182" "1" "11" "22" "42528030" "42528056" "del" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000119183" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119184" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000119185" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119186" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119187" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119188" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119189" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119190" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119191" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119192" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119193" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119194" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119195" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119196" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119197" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119198" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119199" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119200" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119201" "2" "33" "22" "42526763" "42526763" "subst" "0.0381894" "01334" "CYP2D6_000087" "g.42526763C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000119202" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000119203" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119204" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119205" "2" "30" "22" "42528030" "42528056" "dup" "0" "01334" "CYP2D6_000116" "g.42528030_42528056T[25]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTT" "" "Germline" "" "" "0" "" "" "g.42132047_42132049dup" "" "likely benign" "" "0000119206" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000119207" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000119208" "1" "11" "22" "42525625" "42525625" "subst" "0" "01334" "CYP2D6_000108" "g.42525625C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129623C>T" "" "benign" "" "0000119209" "1" "10" "22" "42528030" "42528056" "del" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000119210" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119211" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000119212" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119213" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119214" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119215" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119216" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119217" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119218" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119219" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119220" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119221" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119222" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119223" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119224" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119225" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119226" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119227" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119228" "2" "33" "22" "42526763" "42526763" "subst" "0.0381894" "01334" "CYP2D6_000087" "g.42526763C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000119229" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000119230" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119231" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119232" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000119233" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000119234" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000119235" "3" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119236" "3" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000119237" "3" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119238" "3" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119239" "3" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119240" "3" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119241" "3" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119242" "3" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119243" "3" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119244" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119245" "3" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119246" "3" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119247" "3" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119248" "3" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119249" "3" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119250" "3" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119251" "3" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119252" "3" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119253" "3" "33" "22" "42526763" "42526763" "subst" "0.0381894" "01334" "CYP2D6_000087" "g.42526763C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130761C>T" "" "likely benign" "" "0000119254" "3" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000119255" "3" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119256" "3" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119257" "3" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000119258" "3" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000119259" "3" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000119263" "1" "99" "22" "42524244" "42524244" "del" "0.0123819" "01334" "CYP2D6_000016" "g.42524244del" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128242del" "" "pathogenic" "" "0000119264" "1" "10" "22" "42528030" "42528056" "del" "0" "01334" "CYP2D6_000113" "g.42528030_42528056T[21]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049del" "" "benign" "" "0000119265" "2" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119266" "2" "11" "22" "42522140" "42522141" "del" "0" "01334" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42126133_42126135delTGT" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126133_42126135del" "" "benign" "" "0000119267" "2" "11" "22" "42522312" "42522312" "subst" "0" "01334" "CYP2D6_000056" "g.42522312=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119268" "2" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119269" "2" "11" "22" "42523003" "42523003" "subst" "0" "01334" "CYP2D6_000035" "g.42523003G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119270" "2" "11" "22" "42523209" "42523209" "subst" "0" "01334" "CYP2D6_000054" "g.42523209C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119271" "2" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119272" "2" "11" "22" "42523943" "42523943" "subst" "0" "01334" "CYP2D6_000012" "g.42523943=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119273" "2" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119274" "2" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119275" "2" "11" "22" "42526049" "42526049" "subst" "0" "01334" "CYP2D6_000049" "g.42526049=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119276" "2" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119277" "2" "11" "22" "42526549" "42526549" "subst" "0" "01334" "CYP2D6_000111" "g.42526549=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119278" "2" "11" "22" "42526561" "42526562" "delins" "0" "01334" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119279" "2" "11" "22" "42526567" "42526567" "subst" "0" "01334" "CYP2D6_000155" "g.42526567=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119280" "2" "11" "22" "42526571" "42526571" "subst" "0" "01334" "CYP2D6_000153" "g.42526571=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119281" "2" "11" "22" "42526573" "42526573" "subst" "0" "01334" "CYP2D6_000154" "g.42526573=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119282" "2" "11" "22" "42526580" "42526580" "subst" "0" "01334" "CYP2D6_000156" "g.42526580=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119283" "2" "30" "22" "42527471" "42527471" "subst" "0" "01334" "CYP2D6_000028" "g.42527471=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131469C>T" "" "likely benign" "" "0000119284" "2" "30" "22" "42527533" "42527533" "subst" "0" "01334" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42131531G>A" "" "likely benign" "" "0000119285" "2" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119286" "2" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000117" "g.42528030_42528056T[26]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "g.42132028insTTTT" "" "Germline" "" "" "0" "" "" "g.42132046_42132049dup" "" "likely benign" "" "0000119287" "2" "30" "22" "42528382" "42528382" "subst" "0" "01334" "CYP2D6_000046" "g.42528382=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "likely benign" "" "0000119288" "2" "30" "22" "42528563" "42528563" "subst" "0" "01334" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EBUILDMISMATCH]: This variant seems to mismatch; the genomic variants on hg19 and hg38 seem to not belong together. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132561C>T" "" "likely benign" "" "0000119289" "3" "11" "22" "42522071" "42522071" "subst" "0" "01334" "CYP2D6_000158" "g.42522071C=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126069A>C" "" "benign" "" "0000119290" "3" "11" "22" "42522392" "42522392" "subst" "0" "01334" "CYP2D6_000064" "g.42522392G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42126390G>A" "" "benign" "" "0000119291" "3" "11" "22" "42522613" "42522613" "subst" "0" "01334" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000119292" "3" "11" "22" "42523211" "42523211" "subst" "0" "01334" "CYP2D6_000063" "g.42523211T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119293" "3" "11" "22" "42523409" "42523409" "subst" "0" "01334" "CYP2D6_000235" "g.42523409=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42127407T>G" "" "benign" "" "0000119294" "3" "30" "22" "42524696" "42524696" "subst" "0" "01334" "CYP2D6_000062" "g.42524696T>C" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42128694T>C" "" "likely benign" "" "0000119295" "3" "11" "22" "42525132" "42525132" "subst" "0" "01334" "CYP2D6_000011" "g.42525132=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119296" "3" "11" "22" "42525756" "42525756" "subst" "0.0769451" "01334" "CYP2D6_000040" "g.42525756G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129754G>A" "" "benign" "" "0000119297" "3" "11" "22" "42525952" "42525952" "subst" "0" "01334" "CYP2D6_000050" "g.42525952=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119298" "3" "11" "22" "42526484" "42526484" "subst" "0" "01334" "CYP2D6_000048" "g.42526484=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119299" "3" "99" "22" "42526694" "42526694" "subst" "0.206804" "01334" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000119300" "3" "30" "22" "42527793" "42527793" "subst" "0" "01334" "CYP2D6_000066" "g.42527793C>T" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42131791C>T" "" "likely benign" "" "0000119301" "3" "30" "22" "42528028" "42528028" "subst" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "likely benign" "" "0000119302" "3" "30" "22" "42528030" "42528056" "" "0" "01334" "CYP2D6_000114" "g.42528030_42528056T[23]" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "" "Germline" "" "" "0" "" "" "g.42132049dup" "" "likely benign" "" "0000119303" "3" "30" "22" "42528219" "42528219" "subst" "0" "01334" "CYP2D6_000065" "g.42528219G>A" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42132217G>A" "" "likely benign" "" "0000119304" "2" "33" "22" "42522946" "42522946" "subst" "0.000339513" "01334" "CYP2D6_000209" "g.42522946C>T" "" "Beurmans, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42126944C>T" "" "likely benign" "" "0000119306" "2" "11" "22" "42528028" "42528028" "" "0" "01334" "CYP2D6_000026" "g.42528028=" "" "Beurmans, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132026T>C" "" "benign" "" "0000119311" "1" "11" "22" "42524696" "42524696" "subst" "0" "01334" "CYP2D6_000062" "g.42524696T>C" "" "Beurmans, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42128694T>C" "" "benign" "" "0000119313" "1" "11" "22" "42524696" "42524696" "subst" "0" "01334" "CYP2D6_000062" "g.42524696T>C" "" "Beurmans, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42128694T>C" "" "benign" "" "0000119314" "1" "00" "22" "42528091" "42528091" "subst" "0" "00006" "CYP2D6_000047" "g.42528091C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1298G>A" "reference haplotype CYP2D6*2L (formerly CYP2D6*41B)\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "yes" "rs59099247" "0" "" "" "" "" "" "" "0000119315" "1" "99" "22" "42525035" "42525035" "subst" "0.000960713" "00006" "CYP2D6_000072" "g.42525035C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1758G>A(G169R)" "reference haplotype CYP2D6*14B; no activity (Gly169Arg)" "Germline" "yes" "rs5030865" "0" "" "" "g.42129033C>T" "" "pathogenic" "" "0000119316" "1" "99" "22" "" "" "" "" "00006" "CYP2D6_000000" "g.(?_42522576)_(42526793_?)[2]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*4X2; NOTE borders of the duplication to be checked" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000119317" "1" "99" "22" "42525035" "42525035" "subst" "0.000960713" "00006" "CYP2D6_000072" "g.42525035C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1758G>A (G169R)" "reference haplotype CYP2D6*14A; no activity (Gly169Arg)" "Germline" "yes" "rs5030865" "0" "" "" "g.42129033C>T" "" "pathogenic" "" "0000119318" "2" "99" "22" "42522575" "42526792" "" "0" "01334" "CYP2D6_000279" "g.(?_42522575)_(42526792_?)dup" "" "Beurmans, submitted" "" "CYP2D6 duplicated" "" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000119319" "2" "99" "22" "42525772" "42525772" "subst" "0.013838" "01334" "CYP2D6_000022" "g.42525772G>A" "" "Beurmans, submitted" "" "" "" "Germline" "yes" "" "0" "" "" "g.42129770G>A" "" "pathogenic" "" "0000119320" "1" "99" "22" "42522575" "42526792" "" "0" "01334" "CYP2D6_000279" "g.(?_42522575)_(42526792_?)dup" "" "Beurmans, submitted" "" "CYP2D6 duplicated" "" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000119321" "2" "99" "22" "42522576" "42526793" "" "0" "00006" "CYP2D6_000000" "g.(?_42522576)_(42526793_?)dup" "" "Beurmans, submitted" "" "CYP2D6 duplicated" "" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000119322" "1" "99" "22" "42522575" "42526792" "" "0" "01334" "CYP2D6_000279" "g.(?_42522575)_(42526792_?)dup" "" "{PMID:Buermans 2017:28044414}, {DOI:Buermans 2017:10.1002/humu.23166}" "" "CYP2D6 duplicated" "" "Germline" "yes" "" "0" "" "" "" "" "pathogenic" "" "0000119374" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*17XN" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119375" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*17XN\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119376" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*17XN" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119377" "1" "99" "22" "" "" "subst" "" "00006" "CYP2D6_000000" "g.(?_42522576)_(42526793_?)[N]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "N = 2, 3, 4, 5, 13" "reference haplotype CYP2D6*17XN" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000119378" "1" "50" "22" "42525772" "42525772" "subst" "0.013838" "00006" "CYP2D6_000022" "g.42525772G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1023C>T (T107I)" "reference haplotype CYP2D6*17XN" "Germline" "" "rs28371706" "0" "" "" "g.42129770G>A" "" "VUS" "" "0000119379" "1" "70" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*10X2" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "likely pathogenic" "" "0000119380" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*10X2\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119381" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*10X2" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119382" "1" "99" "22" "42522575" "42526792" "subst" "0" "00006" "CYP2D6_000279" "g.(?_42522575)_(42526792_?)dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "CYP2D6 duplicated" "reference haplotype CYP2D6*10X2" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000119383" "1" "10" "22" "42528563" "42528563" "subst" "0" "00006" "CYP2D6_000109" "g.42528563=" "" "{PMID:Skierka 2012:22676198}" "" "-1770G>A" "fully sequenced allele" "Germline" "" "rs1080983" "0" "" "" "g.42132556=" "" "benign" "" "0000119384" "1" "50" "22" "42528382" "42528382" "subst" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "{PMID:Skierka 2012:22676198}" "" "-1584C>G" "fully sequenced allele" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000119385" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "{PMID:Skierka 2012:22676198}" "" "-1235A>G" "fully sequenced allele" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119386" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Skierka 2012:22676198}" "" "-740C>T" "fully sequenced allele\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000119387" "1" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "{PMID:Skierka 2012:22676198}" "" "-678G>A" "fully sequenced allele" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000119388" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "{PMID:Skierka 2012:22676198}" "" "214G>C (1i conversion)" "fully sequenced allele" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119389" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "{PMID:Skierka 2012:22676198}" "" "221C>A (1i conversion)" "fully sequenced allele" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119390" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "{PMID:Skierka 2012:22676198}" "" "223C>G (1i conversion)" "fully sequenced allele" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119391" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "{PMID:Skierka 2012:22676198}" "" "227T>C (1i conversion)" "fully sequenced allele" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119392" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Skierka 2012:22676198}" "" "232G>C; 233A>C (1i conversion)" "fully sequenced allele" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119393" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "{PMID:Skierka 2012:22676198}" "" "245A>G (1i conversion)" "fully sequenced allele" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119394" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "{PMID:Skierka 2012:22676198}" "" "310G>T" "fully sequenced allele" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119395" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "{PMID:Skierka 2012:22676198}" "" "746C>G" "fully sequenced allele" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119396" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "{PMID:Skierka 2012:22676198}" "" "843T>G" "fully sequenced allele" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119397" "1" "99" "22" "42525912" "42525912" "subst" "0.000118933" "00006" "CYP2D6_000020" "g.42525912C>G" "" "{PMID:Skierka 2012:22676198}" "" "883G>C (spl)" "fully sequenced allele" "Germline" "" "" "0" "" "" "g.42129910C>G" "" "pathogenic" "" "0000119398" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Skierka 2012:22676198}" "" "2850C>T (R296C)" "fully sequenced allele" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119399" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "{PMID:Skierka 2012:22676198}" "" "3384A>C" "fully sequenced allele" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119400" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "{PMID:Skierka 2012:22676198}" "" "3584G>A" "fully sequenced allele" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119401" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "{PMID:Skierka 2012:22676198}" "" "3790C>T" "fully sequenced allele" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119402" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Skierka 2012:22676198}" "" "4180G>C (S486T)" "fully sequenced allele\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119403" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "{PMID:Skierka 2012:22676198}" "" "4481G>A" "fully sequenced allele" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119407" "1" "30" "22" "42527896" "42527896" "dup" "0" "00006" "CYP2D6_000143" "g.42527896dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1094_-1093insA" "reference haplotype CYP2D6*45B" "Germline" "" "" "0" "" "" "g.42131894dup" "" "likely benign" "" "0000119408" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*45B\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000119409" "1" "30" "22" "42527487" "42527490" "del" "0" "00006" "CYP2D6_000144" "g.42527487_42527490del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-695_-692delTGTG" "reference haplotype CYP2D6*45B" "Germline" "" "" "0" "" "" "g.42131485_42131488del" "" "likely benign" "" "0000119410" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*45B" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119411" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*45B" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119412" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*45B" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119413" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*45B" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119414" "1" "77" "22" "42525077" "42525077" "subst" "0.00318442" "00006" "CYP2D6_000030" "g.42525077C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1716G>A (E155K)" "reference haplotype CYP2D6*45B; slightly reduced activity" "Germline" "" "rs28371710" "0" "" "" "g.42129075C>T" "" "likely pathogenic" "" "0000119415" "1" "11" "22" "42524218" "42524218" "subst" "0.00765363" "00006" "CYP2D6_000038" "g.42524218G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2575C>A" "reference haplotype CYP2D6*45B" "Germline" "" "rs28371718" "0" "" "" "g.42128216G>T" "" "benign" "" "0000119416" "1" "33" "22" "42524132" "42524132" "subst" "0.00741985" "00006" "CYP2D6_000139" "g.42524132C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2661G>A" "reference haplotype CYP2D6*45B" "Germline" "" "rs76015180" "0" "" "" "g.42128130C>T" "" "likely benign" "" "0000119417" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*45B" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119418" "1" "33" "22" "42523539" "42523539" "subst" "0" "00006" "CYP2D6_000141" "g.42523539A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3254T>C" "reference haplotype CYP2D6*45B" "Germline" "" "rs28371726" "0" "" "" "g.42127537A>G" "" "likely benign" "" "0000119419" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*45B" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119420" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*45B" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119421" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*45B" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119422" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*45B\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119423" "1" "10" "22" "42528394" "42528394" "subst" "0" "00006" "CYP2D6_000146" "g.42528394G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1601_-1600GA>TT" "reference haplotype CYP2D6*45A" "Germline" "" "" "0" "" "" "g.42132387G>A" "" "benign" "" "0000119427" "1" "30" "22" "42528028" "42528028" "del" "0" "00006" "CYP2D6_000000" "g.42528030_42528056T[N]" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1258-1237A[N]" "reference haplotype CYP2D6*45A\r\nVariant Error [ESYNTAX]: This genomic variant has an error (char 33: expected one of \'=\', or \'>\'). Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "" "" "likely benign" "" "0000119428" "1" "30" "22" "42527896" "42527896" "dup" "0" "00006" "CYP2D6_000143" "g.42527896dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1094_-1093insA" "reference haplotype CYP2D6*45A" "Germline" "" "" "0" "" "" "g.42131894dup" "" "likely benign" "" "0000119429" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*45A" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119430" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*45A" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119431" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*45A" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119432" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*45A" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119433" "1" "77" "22" "42525077" "42525077" "subst" "0.00318442" "00006" "CYP2D6_000030" "g.42525077C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1716G>A (E155K)" "reference haplotype CYP2D6*45A; slightly reduced activity" "Germline" "" "rs28371710" "0" "" "" "g.42129075C>T" "" "likely pathogenic" "" "0000119434" "1" "10" "22" "42524664" "42524664" "subst" "0" "00006" "CYP2D6_000145" "g.42524664T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2129A>C" "reference haplotype CYP2D6*45A" "Germline" "" "" "0" "" "" "g.42128662T>G" "" "benign" "" "0000119435" "1" "11" "22" "42524218" "42524218" "subst" "0.00765363" "00006" "CYP2D6_000038" "g.42524218G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2575C>A" "reference haplotype CYP2D6*45A" "Germline" "" "rs28371718" "0" "" "" "g.42128216G>T" "" "benign" "" "0000119436" "1" "33" "22" "42524132" "42524132" "subst" "0.00741985" "00006" "CYP2D6_000139" "g.42524132C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2661G>A" "reference haplotype CYP2D6*45A" "Germline" "" "rs76015180" "0" "" "" "g.42128130C>T" "" "likely benign" "" "0000119437" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*45A" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119438" "1" "33" "22" "42523763" "42523763" "subst" "0" "00006" "CYP2D6_000142" "g.42523763C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3030G>G/A" "reference haplotype CYP2D6*45A" "Germline" "" "rs267608291" "0" "" "" "g.42127761C>T" "" "likely benign" "" "0000119439" "1" "33" "22" "42523539" "42523539" "subst" "0" "00006" "CYP2D6_000141" "g.42523539A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3254T>C" "reference haplotype CYP2D6*45A" "Germline" "" "rs28371726" "0" "" "" "g.42127537A>G" "" "likely benign" "" "0000119440" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*45A" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119441" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*45A" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119442" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*45A" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119443" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*45A\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119444" "1" "50" "22" "42528336" "42528336" "subst" "0" "00006" "CYP2D6_000138" "g.42528336C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1543G>A" "reference haplotype CYP2D6*45B\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs76210340" "0" "" "" "" "" "VUS" "" "0000119445" "1" "50" "22" "42528091" "42528091" "subst" "0" "00006" "CYP2D6_000047" "g.42528091C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1298G>A" "reference haplotype CYP2D6*45B\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs59099247" "0" "" "" "" "" "VUS" "" "0000119446" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*45B" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119448" "1" "50" "22" "42528382" "42528382" "subst" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*51; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000119449" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*51" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119450" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*51; NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000119451" "1" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*51; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000119452" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*51" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119453" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*51" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119454" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*51" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119455" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*51" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119456" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*51" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119457" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*51" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119458" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*51" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119459" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*51" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119460" "1" "50" "22" "42523621" "42523621" "subst" "0" "00006" "CYP2D6_000148" "g.42523621T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3172A>C (E334A)" "reference haplotype CYP2D6*51" "Germline" "" "rs72549348" "0" "" "" "g.42127619T>G" "" "VUS" "" "0000119461" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*51\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119462" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*52\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000119463" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*52" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119464" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*52" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000119465" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*52" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000119466" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*52" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000119467" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*52" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119468" "1" "50" "22" "42522916" "42522916" "subst" "0.000735984" "00006" "CYP2D6_000149" "g.42522916C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3877G>A (E418K)" "reference haplotype CYP2D6*52" "Germline" "" "rs28371733" "0" "" "" "g.42126914C>T" "" "VUS" "" "0000119469" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*52\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119470" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*52" "Germline" "" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000119471" "1" "50" "22" "42525195" "42525195" "subst" "0" "00006" "CYP2D6_000150" "g.42525195G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1598A>G" "reference haplotype CYP2D6*53\r\nVariant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "" "" "VUS" "" "0000119472" "1" "50" "22" "42525182" "42525182" "subst" "0.001645" "00006" "CYP2D6_000122" "g.42525182A>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1611T>A (F120I)" "reference haplotype CYP2D6*53" "Germline" "" "rs1135822" "0" "" "" "g.42129180A>T" "" "VUS" "" "0000119473" "1" "50" "22" "42525176" "42525176" "subst" "0.000795803" "00006" "CYP2D6_000151" "g.42525176C>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1617G>T (A122S)" "reference haplotype CYP2D6*53" "Germline" "" "rs1135823" "0" "" "" "g.42129174C>A" "" "VUS" "" "0000119474" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*54; decreased activity" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000119475" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*54; decreased activity" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000119476" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*54; decreased activity" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119477" "1" "50" "22" "42524237" "42524237" "subst" "5.73399E-5" "00006" "CYP2D6_000152" "g.42524237G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2556C>T (T261I)" "reference haplotype CYP2D6*54; decreased activity" "Germline" "" "" "0" "" "" "g.42128235G>A" "" "VUS" "" "0000119478" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*54; decreased activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119479" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*55" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119480" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*55" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119481" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*55; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119482" "1" "50" "22" "42522958" "42522958" "subst" "0" "00006" "CYP2D6_000159" "g.42522958T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3835A>C (K404Q)" "reference haplotype CYP2D6*55" "Germline" "" "" "0" "" "" "g.42126956T>G" "" "VUS" "" "0000119483" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*55\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119484" "1" "50" "22" "42528382" "42528382" "subst" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*56A; no activity; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000119485" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119486" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*56A; no activity; NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000119487" "1" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*56A; no activity; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000119488" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119489" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119490" "1" "99" "22" "42523592" "42523592" "subst" "0.000142389" "00006" "CYP2D6_000160" "g.42523592G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3201C>T (R344X)" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs147960066" "0" "" "" "g.42127590G>A" "" "pathogenic" "" "0000119491" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119492" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*56A; no activity; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119493" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*56A; no activity; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119494" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*56A; no activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119495" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119496" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119497" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119498" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119499" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119500" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*56A; no activity" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119501" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*56B; no activity\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000119502" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*56B; no activity" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119503" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000G>A" "reference haplotype CYP2D6*56B; no activity" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000119504" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*56B; no activity" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000119505" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*56B; no activity; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119506" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*56B; no activity; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119507" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*56B; no activity" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000119508" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*56B; no activity" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119509" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*56B; no activity" "Germline" "" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000119510" "1" "99" "22" "42523592" "42523592" "subst" "0.000142389" "00006" "CYP2D6_000160" "g.42523592G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3201C>T (R344X)" "reference haplotype CYP2D6*56B; no activity" "Germline" "yes" "rs147960066" "0" "" "" "g.42127590G>A" "" "pathogenic" "" "0000119511" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*56B; no activity" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119512" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*56B; no activity" "Germline" "" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119513" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*56B; no activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119514" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*58\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000119515" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*58" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119516" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*58; NOTE reference sequence is not CYP2D6*1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000119517" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*58; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119518" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*58; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119519" "1" "50" "22" "42525772" "42525772" "subst" "0.013838" "00006" "CYP2D6_000022" "g.42525772G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1023C>T (T107I)" "reference haplotype CYP2D6*58" "Germline" "" "rs28371706" "0" "" "" "g.42129770G>A" "" "VUS" "" "0000119520" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*58" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119521" "1" "99" "22" "42524936" "42524944" "dup" "0" "00006" "CYP2D6_000085" "g.42524936_42524944dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1863_1864insTTTCGCCCC (174_175insFRP)" "reference haplotype CYP2D6*58; no activity" "Germline" "" "rs553846709" "0" "" "" "g.42128934_42128942dup" "" "pathogenic" "" "0000119522" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*58" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119523" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*58" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119524" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*58; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119525" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*58; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119526" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*58\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119527" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*58" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119528" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*58" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119529" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*58" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119530" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*58" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119531" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*58" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119532" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*58" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119533" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*57" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000119534" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*57; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119535" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*57; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119536" "1" "50" "22" "42525908" "42525908" "subst" "2.93738E-5" "00006" "CYP2D6_000161" "g.42525908G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "887C>T (R62W)" "reference haplotype CYP2D6*57" "Germline" "" "" "0" "" "" "g.42129906G>A" "" "VUS" "" "0000119537" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*57" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000119538" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*57" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119539" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*57" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119540" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*57" "Germline" "" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119541" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*57\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119542" "1" "11" "22" "42522669" "42522669" "subst" "0.00010518" "00006" "CYP2D6_000034" "g.42522669C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4124G>C; con ex9" "reference haplotype CYP2D6*57" "Germline" "" "rs1135832" "0" "" "" "g.42126667C>G" "" "benign" "" "0000119543" "1" "50" "22" "42522662" "42522663" "delins" "0" "00006" "CYP2D6_000182" "g.42522662_42522663delinsGC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4128C>G (P469A); con ex9" "reference haplotype CYP2D6*57" "Germline" "" "rs1135833" "0" "" "" "g.42126660_42126661delinsGC" "" "VUS" "" "0000119544" "1" "50" "22" "42522662" "42522662" "subst" "7.0729E-5" "00006" "CYP2D6_000183" "g.42522662T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4131A>G (T470A); con ex9" "reference haplotype CYP2D6*57" "Germline" "" "rs1135835" "0" "" "" "g.42126660T>C" "" "VUS" "" "0000119545" "1" "11" "22" "42522660" "42522660" "subst" "8.7255E-5" "00006" "CYP2D6_000184" "g.42522660A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4133T>C; con ex9" "reference haplotype CYP2D6*57" "Germline" "" "" "0" "" "" "g.42126658A>G" "" "benign" "" "0000119546" "1" "50" "22" "42522637" "42522638" "delins" "0" "00006" "CYP2D6_000185" "g.42522637_42522638delinsGA" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4155C>T;4156A>C (H478S); con ex9" "reference haplotype CYP2D6*57" "Germline" "" "" "0" "" "" "g.42126635_42126636delinsGA" "" "VUS" "" "0000119547" "1" "50" "22" "42522635" "42522635" "subst" "0" "00006" "CYP2D6_000186" "g.42522635C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4158G>C (G479R); con ex9" "reference haplotype CYP2D6*57" "Germline" "" "rs1135837" "0" "" "" "g.42126633C>G" "" "VUS" "" "0000119548" "1" "50" "22" "42522629" "42522629" "subst" "0" "00006" "CYP2D6_000187" "g.42522629A>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4164T>G (F481V); con ex9" "reference haplotype CYP2D6*57" "Germline" "" "" "0" "" "" "g.42126627A>C" "" "VUS" "" "0000119549" "1" "50" "22" "42522624" "42522627" "delins" "0" "00006" "CYP2D6_000188" "g.42522624_42522627delinsGCTG" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4166T>C;4167G>A;4168C>G;4169T>C (A482S); con ex9" "reference haplotype CYP2D6*57" "Germline" "" "" "0" "" "" "g.42126622_42126625delinsGCTG" "" "VUS" "" "0000119550" "1" "11" "22" "42522621" "42522621" "subst" "0" "00006" "CYP2D6_000189" "g.42522621G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4172C>T; con ex9" "reference haplotype CYP2D6*57" "Germline" "" "rs28371736" "0" "" "" "g.42126619G>A" "" "benign" "" "0000119551" "1" "11" "22" "42522600" "42522600" "subst" "0.000237399" "00006" "CYP2D6_000190" "g.42522600A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4193T>C; con ex9" "reference haplotype CYP2D6*57" "Germline" "" "rs61731577" "0" "" "" "g.42126598A>G" "" "benign" "" "0000119552" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*65" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000119553" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*65; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119554" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*65; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119555" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*65" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119556" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*65" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119557" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*65" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119558" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*65; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119559" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*65; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119560" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*65\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119561" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*65" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119562" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*64; activity untested (probably decreased)\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000119563" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119564" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000119565" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "yes" "rs1065852" "0" "" "" "g.42130692G>A" "" "pathogenic" "" "0000119566" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*64; activity untested (probably decreased); NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119567" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*64; activity untested (probably decreased); NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119568" "1" "50" "22" "42525772" "42525772" "subst" "0.013838" "00006" "CYP2D6_000022" "g.42525772G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1023C>T (T107I)" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "" "rs28371706" "0" "" "" "g.42129770G>A" "" "VUS" "" "0000119569" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119570" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000119571" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119572" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119573" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*64; activity untested (probably decreased)\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119574" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*64; activity untested (probably decreased)" "Germline" "" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000119595" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*21B" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119596" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*21B" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119597" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*21B" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119598" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*21B" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119599" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*21B" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119600" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*21B" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119601" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*98; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119602" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*98; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119603" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*98" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119604" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*98" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119605" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*98" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119606" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*98" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119607" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*98" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119608" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*98" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119609" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*98" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119610" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*98" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119611" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*98" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119612" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*98; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000119613" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*98; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119614" "1" "50" "22" "42522683" "42522683" "subst" "0" "00006" "CYP2D6_000162" "g.42522683G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4110C>G (H463D)" "reference haplotype CYP2D6*98" "Germline" "" "" "0" "" "" "g.42126681G>C" "" "VUS" "" "0000119615" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*98\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119616" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*100\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000119617" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*100" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119618" "1" "11" "22" "42527902" "42527902" "subst" "0" "00006" "CYP2D6_000163" "g.42527902G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1109C>T" "reference haplotype CYP2D6*100" "Germline" "" "" "0" "" "" "g.42131900G>A" "" "benign" "" "0000119619" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*100" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000119620" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*100" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000119621" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*100; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119622" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*100; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119623" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*100" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000119624" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*100" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119625" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*100" "Germline" "" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000119626" "1" "99" "22" "42523965" "42523965" "subst" "8.9476E-5" "00006" "CYP2D6_000164" "g.42523965G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2828delC (288fs)" "reference haplotype CYP2D6*100" "Germline" "" "" "0" "" "" "g.42127963G>A" "" "pathogenic" "" "0000119627" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*100" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119628" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*100" "Germline" "" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119629" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*100\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119630" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*100" "Germline" "" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000119631" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*101\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000119632" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*101" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000119633" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*101" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000119634" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*101" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000119635" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*101; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119636" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*101; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119637" "1" "11" "22" "42525756" "42525756" "subst" "0.0769451" "00006" "CYP2D6_000040" "g.42525756G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1039C>T" "reference haplotype CYP2D6*101" "Germline" "" "rs1081003" "0" "" "" "g.42129754G>A" "" "benign" "" "0000119638" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*101" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119639" "1" "11" "22" "42524696" "42524696" "subst" "0" "00006" "CYP2D6_000062" "g.42524696T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2097A>G" "reference haplotype CYP2D6*101" "Germline" "" "rs58440431" "0" "" "" "g.42128694T>C" "" "benign" "" "0000119640" "1" "90" "22" "42523848" "42523866" "subst" "0" "00006" "CYP2D6_000165" "g.42523848_42523866T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2927_2945delGATCCTACATCCGGATGTG (321fs)" "reference haplotype CYP2D6*101\r\nVariant Error [EREF/0]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000119641" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*101" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119642" "1" "11" "22" "42523211" "42523211" "subst" "0" "00006" "CYP2D6_000063" "g.42523211T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3582A>G" "reference haplotype CYP2D6*101" "Germline" "" "rs2004511" "0" "" "" "g.42127209T>C" "" "benign" "" "0000119643" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*101\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119644" "1" "11" "22" "42522392" "42522392" "subst" "0" "00006" "CYP2D6_000064" "g.42522392G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4401C>T" "reference haplotype CYP2D6*101" "Germline" "" "rs28371738" "0" "" "" "g.42126390G>A" "" "benign" "" "0000119645" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*102; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119646" "1" "30" "22" "42525823" "42525823" "subst" "0" "00006" "CYP2D6_000093" "g.42525823G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "972C>T (A90V)" "reference haplotype CYP2D6*102" "Germline" "" "rs267608309" "0" "" "" "g.42129821G>A" "" "likely benign" "" "0000119647" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*102" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119648" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*102" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119649" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*102" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119650" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*102" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119651" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*102" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119652" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*102" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119653" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*102" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119654" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*102" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119655" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*102" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119656" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*102; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119657" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*102\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119658" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*102" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119674" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*103; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119675" "1" "30" "22" "42525823" "42525823" "subst" "0" "00006" "CYP2D6_000093" "g.42525823G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "972C>T (A90V)" "reference haplotype CYP2D6*103" "Germline" "" "rs267608309" "0" "" "" "g.42129821G>A" "" "likely benign" "" "0000119676" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*103" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119677" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*103" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119678" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*103" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119679" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*103" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119680" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*103" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119681" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*103" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119682" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*103" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119683" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*103" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119684" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*103" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119685" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*103; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119686" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*103\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119687" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*103" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119688" "1" "55" "22" "42525044" "42525044" "subst" "0" "00006" "CYP2D6_000057" "g.42525044T>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1749A>G (N166D)" "reference haplotype CYP2D6*103" "Germline" "" "rs1135824" "0" "" "" "g.42129042T>C" "" "VUS" "" "0000119689" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*104; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119690" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*104; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119691" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*104" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119692" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*104" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119693" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*104" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119694" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*104" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119695" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*104" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119696" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*104" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119697" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*104" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119698" "1" "90" "22" "42525073" "42525073" "subst" "2.51722E-5" "00006" "CYP2D6_000094" "g.42525073T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1720A>C (E156A)" "reference haplotype CYP2D6*104" "Germline" "" "rs267608302" "0" "" "" "g.42129071T>G" "" "pathogenic" "" "0000119699" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*104" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119700" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*104" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119701" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*104; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119702" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*104\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119703" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*104" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119704" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*105; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000119705" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*105; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000119706" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*105; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000119707" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*105" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000119708" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*105" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000119709" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*105" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000119710" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*105" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000119711" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*105" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000119712" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*105" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000119713" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*105" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000119714" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*105" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000119715" "1" "50" "22" "42523525" "42523525" "subst" "0" "00006" "CYP2D6_000166" "g.42523525A>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3268T>C (F366S)" "reference haplotype CYP2D6*105" "Germline" "" "" "0" "" "" "g.42127523A>G" "" "VUS" "" "0000119716" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*105" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000119717" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*105; NOTE reference sequence is not CYP2D6*1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000119718" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4180G>C (S486T)" "reference haplotype CYP2D6*105\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000119719" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "4481G>A" "reference haplotype CYP2D6*105" "Germline" "" "rs116390392" "0" "" "" "g.42126310C>T" "" "benign" "" "0000119720" "1" "70" "22" "42525134" "42525134" "subst" "0.00667974" "00006" "CYP2D6_000169" "g.42525134C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1659G>A (V136M)" "reference haplotype CYP2D6*107" "Germline" "" "rs61736512" "0" "" "" "g.42129132C>T" "" "likely pathogenic" "" "0000119721" "1" "11" "22" "42527753" "42527753" "subst" "0" "00006" "CYP2D6_000168" "g.42527753C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-960G>C" "reference haplotype CYP2D6*109" "Germline" "" "" "0" "" "" "g.42131751C>G" "" "benign" "" "0000119722" "1" "50" "22" "42524178" "42524180" "del" "0" "00006" "CYP2D6_000014" "g.42524178_42524180del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2615-2617delAAG (K281del)" "reference haplotype CYP2D6*109" "Germline" "" "rs5030656" "0" "" "" "g.42128176_42128178del" "" "VUS" "" "0000119723" "1" "50" "22" "42523610" "42523610" "subst" "0.00647036" "00006" "CYP2D6_000024" "g.42523610C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3183G>A (V338M)" "reference haplotype CYP2D6*109" "Germline" "" "rs59421388" "0" "" "" "g.42127608C>T" "" "VUS" "" "0000150630" "1" "90" "22" "42519215" "42531371" "del" "0" "00006" "CYP2D6_000210" "g.42519215_42531371del" "" "" "" "" "" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000150631" "1" "10" "22" "42531392" "42531392" "subst" "0" "00006" "CYP2D6_000211" "g.42531392A>G" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42135383A>G" "" "benign" "" "0000150632" "3" "10" "22" "42531700" "42531700" "subst" "0" "00006" "CYP2D6_000212" "g.42531700C>T" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42135691=" "" "benign" "" "0000150633" "3" "10" "22" "42531792" "42531792" "subst" "0" "00006" "CYP2D6_000213" "g.42531792T>C" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42135783=" "" "benign" "" "0000150634" "2" "10" "22" "42519472" "42519472" "del" "0" "00006" "CYP2D6_000214" "g.42519472del" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42123467del" "" "benign" "" "0000150637" "2" "10" "22" "42519544" "42519544" "subst" "0" "00006" "CYP2D6_000215" "g.42519544C>T" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42123539=" "" "benign" "" "0000150638" "2" "10" "22" "42519636" "42519636" "subst" "0" "00006" "CYP2D6_000216" "g.42519636T>C" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42123631=" "" "benign" "" "0000150639" "2" "30" "22" "42522613" "42522613" "subst" "0.452389" "00006" "CYP2D6_000010" "g.42522613G>C" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42126611=" "" "likely benign" "" "0000150640" "2" "10" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312T>C" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42126310=" "" "benign" "" "0000150641" "1" "10" "22" "42523003" "42523003" "subst" "0.320428" "00006" "CYP2D6_000035" "g.42523003A>G" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42127001=" "" "benign" "" "0000150643" "2" "10" "22" "42523943" "42523943" "subst" "0.660155" "00006" "CYP2D6_000234" "g.42523943A>G" "" "" "" "" "" "Germline" "" "" "0" "" "" "g.42127941=" "" "benign" "" "0000150764" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*61" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000150765" "1" "11" "22" "42523409" "42523409" "" "0" "00006" "CYP2D6_000235" "g.42523409=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "3384A>C" "" "Germline" "" "rs1985842" "0" "" "" "g.42127407T>G" "" "benign" "" "0000150766" "1" "90" "22" "42522600" "42523315" "" "0" "00006" "CYP2D6_000000" "g.42522600_42523315con42536313_42537029" "" "Reference \tReference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*61; conversion to CYP2D7 sequence" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000150767" "1" "90" "22" "42522600" "42523315" "" "0" "00006" "CYP2D6_000000" "g.42522600_42523315con42536313_42537029" "" "{PMID:Kramer 2009:19741566}" "" "" "conversion to CYP2D7 sequence" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000150768" "1" "50" "22" "42528382" "42528382" "subst" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1584C>G" "reference haplotype CYP2D6*63" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000150769" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*63" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000150770" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-740C>T" "reference haplotype CYP2D6*63\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000150771" "1" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-678G>A" "reference haplotype CYP2D6*63" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000150772" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G>C (1i conversion)" "reference haplotype CYP2D6*63" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000150773" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C>A (1i conversion)" "reference haplotype CYP2D6*63" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000150774" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C>G (1i conversion)" "reference haplotype CYP2D6*63" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000150775" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T>C (1i conversion)" "reference haplotype CYP2D6*63" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000150776" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G>C; 233A>C (1i conversion)" "reference haplotype CYP2D6*63" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000150777" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A>G (1i conversion)" "reference haplotype CYP2D6*63" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000150778" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*63" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000150779" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "746C>G" "reference haplotype CYP2D6*63" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000150780" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "843T>G" "reference haplotype CYP2D6*63" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000150781" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "1661G>C" "reference haplotype CYP2D6*63" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000150782" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "2850C>T (R296C)" "reference haplotype CYP2D6*63" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000150783" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3384A>C" "reference haplotype CYP2D6*63" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000150784" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3584G>A" "reference haplotype CYP2D6*63" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000150785" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "3790C>T" "reference haplotype CYP2D6*63" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000150786" "1" "50" "22" "42528382" "42528382" "subst" "0" "00006" "CYP2D6_000046" "g.42528382=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "-1584C>G" "" "Germline" "" "rs1080985" "0" "" "" "g.42132375G>C" "" "VUS" "" "0000150787" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "-1235A>G" "" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000150788" "1" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "-740C>T" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000150789" "1" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "-678G>A" "" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000150790" "1" "10" "22" "42526580" "42526580" "subst" "0" "00006" "CYP2D6_000156" "g.42526580=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "214G>C (1i conversion)" "" "Germline" "" "rs1080995" "0" "" "" "g.42130578C>G" "" "benign" "" "0000150791" "1" "11" "22" "42526573" "42526573" "subst" "0" "00006" "CYP2D6_000154" "g.42526573=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "221C>A (1i conversion)" "" "Germline" "" "rs1080996" "0" "" "" "g.42130571G>T" "" "benign" "" "0000150792" "1" "11" "22" "42526571" "42526571" "subst" "0" "00006" "CYP2D6_000153" "g.42526571=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "223C>G (1i conversion)" "" "Germline" "" "rs74644586" "0" "" "" "g.42130569G>C" "" "benign" "" "0000150793" "1" "10" "22" "42526567" "42526567" "subst" "0" "00006" "CYP2D6_000155" "g.42526567=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "227T>C (1i conversion)" "" "Germline" "" "rs76312385" "0" "" "" "g.42130565A>G" "" "benign" "" "0000150794" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000110" "g.42526561_42526562=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "232G>C; 233A>C (1i conversion)" "" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560delinsGG" "" "benign" "" "0000150795" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000111" "g.42526549=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "245A>G (1i conversion)" "" "Germline" "" "rs1081000" "0" "" "" "g.42130547T>C" "" "benign" "" "0000150796" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "310G>T" "" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000150797" "1" "11" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000049" "g.42526049=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "746C>G" "" "Germline" "" "rs28371701" "0" "" "" "g.42130047G>C" "" "benign" "" "0000150798" "1" "11" "22" "42525952" "42525952" "subst" "0" "00006" "CYP2D6_000050" "g.42525952=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "843T>G" "" "Germline" "" "rs28371702" "0" "" "" "g.42129950A>C" "" "benign" "" "0000150799" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "1661G>C" "" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000150800" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "2850C>T (R296C)" "" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000150801" "1" "11" "22" "42523409" "42523409" "subst" "0" "00006" "CYP2D6_000053" "g.42523409G>T" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "3384A>C" "" "Germline" "" "rs1985842" "0" "" "" "g.42127407=" "" "benign" "" "0000150802" "1" "11" "22" "42523209" "42523209" "subst" "0" "00006" "CYP2D6_000054" "g.42523209=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "3584G>A" "" "Germline" "" "rs28371730" "0" "" "" "g.42127207C>T" "" "benign" "" "0000150803" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "3790C>T" "" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000150804" "1" "90" "22" "42522671" "42522719" "" "0" "00006" "CYP2D6_000217" "g.42522671_42522719con42536384_42536382" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*63" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000150805" "1" "90" "22" "42522671" "42522719" "" "0" "00006" "CYP2D6_000217" "g.42522671_42522719con42536384_42536382" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "" "" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000150806" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1426C>T" "reference haplotype CYP2D6*68A\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000150807" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1235A>G" "reference haplotype CYP2D6*68A" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000150808" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "-1000A>G" "reference haplotype CYP2D6*68A" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000150809" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "100C>T (P34S)" "reference haplotype CYP2D6*68A" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000150810" "1" "11" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000048" "g.42526484=" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "310G>T" "reference haplotype CYP2D6*68A" "Germline" "" "rs28371699" "0" "" "" "g.42130482C>A" "" "benign" "" "0000150811" "1" "50" "22" "42528219" "42528219" "subst" "0" "00006" "CYP2D6_000065" "g.42528219G>A" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "-1426C>T" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28588594" "0" "" "" "" "" "VUS" "" "0000150812" "1" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "-1235A>G" "" "Germline" "" "rs28735595" "0" "" "" "" "" "benign" "" "0000150813" "1" "11" "22" "42527793" "42527793" "subst" "0" "00006" "CYP2D6_000066" "g.42527793C>T" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "-1000A>G" "" "Germline" "" "rs1080989" "0" "" "" "g.42131791C>T" "" "benign" "" "0000150814" "1" "50" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "100C>T (P34S)" "" "Germline" "" "rs1065852" "0" "" "" "g.42130692G>A" "" "VUS" "" "0000150816" "1" "10" "22" "42528563" "42528563" "subst" "0" "00006" "CYP2D6_000109" "g.42528563=" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "-1770G>A" "" "Germline" "" "" "0" "" "" "g.42132556=" "" "benign" "" "0000150817" "1" "30" "22" "42528377" "42528377" "subst" "0" "00006" "CYP2D6_000218" "g.42528377C>G" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "-1584C>G" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "" "" "likely benign" "" "0000150818" "1" "30" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000219" "g.42527471T>C" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "-678G>A" "" "Germline" "" "" "0" "" "" "g.42131469=" "" "likely benign" "" "0000150819" "1" "30" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000220" "g.42527533A>G" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "-740C" "" "Germline" "" "" "0" "" "" "g.42131531=" "" "likely benign" "" "0000150820" "1" "10" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530606}" "" "214G= (1i conversion)" "" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000150821" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530606}" "" "221C= (1i conversion)" "" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000150822" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530606}" "" "223C= (1i conversion)" "" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000150823" "1" "10" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530606}" "" "227T= (1i conversion)" "" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000150824" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530606}" "" "232G=; 233A= (1i conversion)" "" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000150825" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530606}" "" "245A= (1i conversion)" "" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000150826" "1" "90" "22" "42524023" "42525821" "" "0" "00006" "CYP2D6_000221" "g.(?_42524023)_42525821con(?_42537725)_42539492" "" "{PMID:Kramer 2009:19741566}, \t{GenBank:EU530606}" "" "" "" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000150827" "1" "10" "22" "42528563" "42528563" "subst" "0" "00006" "CYP2D6_000109" "g.42528563T>C" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "-1770G>A" "" "Germline" "" "" "0" "" "" "g.42132556T>C" "" "benign" "" "0000150828" "1" "10" "22" "42528377" "42528377" "subst" "0" "00006" "CYP2D6_000218" "g.42528377C>G" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "-1584C" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "" "" "benign" "" "0000150829" "1" "10" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000222" "g.42528028C>T" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "-1235G" "" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000150830" "1" "10" "22" "42528052" "42528056" "del" "0" "00006" "CYP2D6_000223" "g.42528052_42528056del" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "42528030T[22]" "" "Germline" "" "" "0" "" "42528030T[22]" "" "" "benign" "" "0000150831" "1" "10" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000220" "g.42527533A>G" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "-740C" "" "Germline" "" "" "0" "" "" "g.42131531=" "" "benign" "" "0000150832" "1" "10" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000219" "g.42527471T>C" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "-678G" "" "Germline" "" "" "0" "" "" "g.42131469=" "" "benign" "" "0000150833" "1" "10" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "214G= (1i conversion)" "" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000150834" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "221C= (1i conversion)" "" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000150835" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "223C= (1i conversion)" "" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000150836" "1" "10" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "227T= (1i conversion)" "" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000150837" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "232G=; 233A= (1i conversion)" "" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000150838" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "245A= (1i conversion)" "" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000150839" "1" "30" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000230" "g.42526484A>C" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530606}" "" "310G=" "" "Germline" "" "" "0" "" "" "g.42130482=" "" "likely benign" "" "0000150840" "1" "30" "22" "42526484" "42526484" "subst" "0" "00006" "CYP2D6_000230" "g.42526484A>C" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "310G" "" "Germline" "" "" "0" "" "" "g.42130482=" "" "likely benign" "" "0000150841" "1" "30" "22" "42526049" "42526049" "subst" "0" "00006" "CYP2D6_000231" "g.42526049C>G" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "746C" "" "Germline" "" "" "0" "" "" "g.42130047=" "" "likely benign" "" "0000150842" "1" "90" "22" "42525952" "42525952" "subst" "0.451208" "00006" "CYP2D6_000232" "g.42525952C>A" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "843T" "" "Germline" "" "" "0" "" "" "g.42129950=" "" "pathogenic" "" "0000150843" "1" "30" "22" "42525132" "42525132" "subst" "0.452484" "00006" "CYP2D6_000233" "g.42525132G>C" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "408G" "" "Germline" "" "" "0" "" "" "g.42129130=" "" "likely benign" "" "0000150844" "1" "30" "22" "42523943" "42523943" "subst" "0.660155" "00006" "CYP2D6_000234" "g.42523943A>G" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530607}" "" "2850C" "" "Germline" "" "" "0" "" "" "g.42127941=" "" "likely benign" "" "0000150845" "1" "30" "22" "42528052" "42528056" "del" "0" "00006" "CYP2D6_000223" "g.42528052_42528056del" "" "{PMID:Kramer 2009:19741566}, {GenBank:EU530608}" "" "42528030T[22]" "" "Germline" "" "" "0" "" "" "" "" "likely benign" "" "0000150847" "1" "11" "22" "42522071" "42522071" "subst" "0" "00006" "CYP2D6_000278" "g.42522071C>A" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:EU098008}" "" "" "reference haplotype CYP2D6*13A1\r\nVariant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "" "" "benign" "" "0000150848" "1" "10" "22" "42522140" "42522141" "del" "0" "00006" "CYP2D6_000167" "g.42522140_42522141=" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:EU098008}" "" "" "reference haplotype CYP2D6*13A1" "Germline" "" "" "0" "" "" "g.42126138_42126139=" "" "benign" "" "0000150849" "1" "11" "22" "42522312" "42522312" "subst" "0" "00006" "CYP2D6_000056" "g.42522312T>C" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:EU098008}" "" "4481G=" "reference haplotype CYP2D6*13A1" "Germline" "" "rs116390392" "0" "" "" "g.42126310=" "" "benign" "" "0000150850" "1" "50" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:EU098008}" "" "4180G>C (S486T)" "reference haplotype CYP2D6*13A1\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "VUS" "" "0000150851" "1" "11" "22" "42523003" "42523003" "subst" "0" "00006" "CYP2D6_000035" "g.42523003=" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:EU098008}" "" "3790C>T" "reference haplotype CYP2D6*13A1" "Germline" "" "rs116917064" "0" "" "" "g.42127001G>A" "" "benign" "" "0000150852" "1" "90" "22" "42526471" "42540141" "del" "0" "00006" "CYP2D6_000236" "g.42526471_42540141del" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:EU098008}" "" "CYP2D7/CYP2D6 hybrid gene" "CYP2D7P1/CYP2D6 hybrid gene" "Germline" "" "" "0" "" "" "g.42129820_42143490del" "" "pathogenic" "" "0000150853" "1" "90" "22" "42526471" "42540141" "del" "0" "00006" "CYP2D6_000236" "g.42526471_42540141del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*13A1 (originally called CYP2D6*13); CYP2D7/2D6 hybrid gene with switch region in intron 1, found as single gene or in tandem arrangements with one or multiple CYP2D6*1 genes" "Germline" "" "" "0" "" "" "g.42129820_42143490del" "" "pathogenic" "" "0000150854" "1" "99" "22" "42526471" "42540141" "del" "0" "00006" "CYP2D6_000237" "g.42526471_42540141del" "" "{PMID:Gaedigk 2010:20017671}, {GenBank:GQ162807}" "" "" "CYP2D7P1/CYP2D6 hybrid gene" "Germline" "" "" "0" "" "" "g.42129820_42143490del" "" "pathogenic" "" "0000150855" "1" "99" "22" "42526471" "42540141" "del" "0" "00006" "CYP2D6_000237" "g.42526471_42540141del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee, {GenBank:GQ162807}" "" "" "reference haplotype CYP2D6*13A2 (originally called CYP2D6*77); CYP2D7/2D6 hybrid gene with switch region in intron 1, found as single gene or in tandem arrangements with one or multiple CYP2D6*1 genes" "Germline" "" "" "0" "" "" "g.42129820_42143490del" "" "pathogenic" "" "0000150856" "1" "99" "22" "42525798" "42539468" "del" "0" "00006" "CYP2D6_000238" "g.42525798_42539468del" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:HM641839}" "" "" "originally called CYP2D6*77" "Germline" "" "" "0" "" "" "g.42129780_42143450del" "" "pathogenic" "" "0000150857" "1" "99" "22" "42525798" "42539468" "del" "0" "00006" "CYP2D6_000238" "g.42525798_42539468del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee, {GenBank:HM641839}" "" "" "reference haplotype CYP2D6*13B (originally called CYP2D6*79); CYP2D7/2D6 hybrid gene with switch region in exon 2, found as single gene or in tandem arrangements with one or multiple CYP2D6*2 genes" "Germline" "yes" "" "0" "" "" "g.42129780_42143450del" "" "pathogenic" "" "0000150858" "1" "99" "22" "42525132" "42538825" "del" "0" "00006" "CYP2D6_000239" "g.42525132_42538825del" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:HM641840}" "" "CYP2D7/2D6 hybrid gene" "CYP2D7P1/2D6 hybrid gene, originally called CYP2D6*80" "Germline" "" "" "0" "" "" "g.42129043_42142736del" "" "pathogenic" "" "0000150859" "1" "99" "22" "42525132" "42538825" "del" "0" "00006" "CYP2D6_000239" "g.42525132_42538825del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*13C (originally called CYP2D6*80); CYP2D7P1/2D6 hybrid gene with switch region in intron 2-exon 3, found as a single gene" "Germline" "yes" "" "0" "" "" "g.42129043_42142736del" "" "pathogenic" "" "0000150860" "1" "99" "22" "42524510" "42538211" "del" "0" "00006" "CYP2D6_000240" "g.42524510_42538211del" "" "{PMID:Gaedigk 2010:20017671}, {GenBank:GQ162808}" "" "CYP2D7/2D6 hybrid gene" "CYP2D7P1/2D6 hybrid gene, originally called CYP2D6*78" "Germline" "" "" "0" "" "" "g.42128434_42142135del" "" "pathogenic" "" "0000150861" "1" "99" "22" "42524510" "42538211" "del" "0" "00006" "CYP2D6_000240" "g.42524510_42538211del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*13D (originally called CYP2D6*78); CYP2D7P1/2D6 hybrid gene with switch region in intron 4, found in tandem arrangement with CYP2D6*2" "Germline" "yes" "" "0" "" "" "g.42128434_42142135del" "" "pathogenic" "" "0000150862" "1" "99" "22" "42524323" "42538024" "del" "0" "00006" "CYP2D6_000241" "g.42524323_42538024del" "" "{PMID:Gaedigk 2010:21833166}, {GenBank:EU098009}" "" "CYP2D7/2D6 hybrid gene" "CYP2D7P1/2D6 hybrid gene, originally called CYP2D6*67" "Germline" "" "" "0" "" "" "g.42128217_42141918del" "" "pathogenic" "" "0000150863" "1" "99" "22" "42524323" "42538024" "del" "0" "00006" "CYP2D6_000241" "g.42524323_42538024del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*13E (originally called CYP2D6*67); CYP2D7P1/2D6 hybrid gene with switch region in exon 5, found as a single gene" "Germline" "yes" "" "0" "" "" "g.42128217_42141918del" "" "pathogenic" "" "0000150864" "1" "99" "22" "42523636" "42537348" "del" "0" "00006" "CYP2D6_000242" "g.42523636_42537348del" "" "{PMID:Gaedigk 2008:18202841}, {GenBank:EU093102}" "" "CYP2D7/2D6 hybrid gene" "CYP2D7P1/2D6 hybrid gene, originally called CYP2D6*16/CYP2D6*66" "Germline" "" "" "0" "" "" "g.42127538_42141250del" "" "pathogenic" "" "0000150865" "1" "99" "22" "42523636" "42537348" "del" "0" "00006" "CYP2D6_000242" "g.42523636_42537348del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*13F (originally called CYP2D6*16/CYP2D6*66); CYP2D7P1/2D6 hybrid gene with switch region in exon 7-intron 8, found as single gene (variants exist with the same switch region characteristics but a few variant nucleotides)" "Germline" "yes" "" "0" "" "" "g.42127538_42141250del" "" "pathogenic" "" "0000150866" "1" "99" "22" "42523003" "42536715" "del" "0" "00006" "CYP2D6_000243" "g.42523003_42536715del" "" "{PMID:Black 2012:22004686}, {GenBank:JN618990}" "" "CYP2D7/2D6 hybrid gene" "CYP2D7P1/2D6 hybrid gene" "Germline" "" "" "0" "" "" "g.42126940_42140652del" "" "pathogenic" "" "0000150867" "1" "99" "22" "42523003" "42536715" "del" "0" "00006" "CYP2D6_000243" "g.42523003_42536715del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*13G1; CYP2D7P1/2D6 hybrid gene with switch region in intron 7, found as a single gene" "Germline" "yes" "" "0" "" "" "g.42126940_42140652del" "" "pathogenic" "" "0000150868" "1" "99" "22" "42522940" "42536652" "del" "0" "00006" "CYP2D6_000244" "g.42522940_42536652del" "" "{PMID:Black 2012:22004686}, {GenBank:HQ670229}" "" "CYP2D7/2D6 hybrid gene" "CYP2D7P1/2D6 hybrid gene" "Germline" "" "" "0" "" "" "g.42126668_42140380del" "" "pathogenic" "" "0000150869" "1" "99" "22" "42522940" "42536652" "del" "0" "00006" "CYP2D6_000244" "g.42522940_42536652del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*13G2; CYP2D7P1/2D6 hybrid gene with switch region in intron 7, found as a single gene" "Germline" "yes" "" "0" "" "" "g.42126668_42140380del" "" "pathogenic" "" "0000150870" "1" "99" "22" "42522660" "42536372" "del" "0" "00006" "CYP2D6_000245" "g.42522660_42536372del" "" "{PMID:Gaedigk 2010:20017671}, {GenBank:GQ162806}" "" "CYP2D7/2D6 hybrid gene" "CYP2D7P1/2D6 hybrid gene, originally called CYP2D6*76" "Germline" "" "" "0" "" "" "g.42126637_42140349del" "" "pathogenic" "" "0000150871" "1" "99" "22" "42522660" "42536372" "del" "0" "00006" "CYP2D6_000245" "g.42522660_42536372del" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*13H (originally called CYP2D6*76); CYP2D7P1/2D6 hybrid gene with witch region in exon 9, found in tandem arrangement with CYP2D6*1" "Germline" "yes" "" "0" "" "" "g.42126637_42140349del" "" "pathogenic" "" "0000150872" "1" "70" "22" "42522575" "42526792" "" "0" "00006" "CYP2D6_000279" "g.(?_42522575)_(42526792_?)dup" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*4N, contains duplicated CYP2D6*4N gene sequence" "Germline" "yes" "" "0" "" "" "" "" "likely pathogenic" "" "0000150873" "1" "30" "22" "42520826" "42522546" "" "0" "00006" "CYP2D6_000246" "g.(42520826_42522546)delins(425334500_425336259)" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "" "reference haplotype CYP2D6*10D, CYP2D7P1-like 3\'-flanking region" "Germline" "yes" "" "0" "" "" "" "" "likely benign" "" "0000150874" "1" "50" "22" "42522581" "42522581" "subst" "4.83691E-5" "00006" "CYP2D6_000247" "g.42522581G>A" "" "{PMID:Qian 2013:24192122}" "" "4212C>T (R497C)" "no haplotype assigned yet" "Germline" "" "rs370580423" "0" "" "" "g.42126579G>A" "" "VUS" "" "0000150875" "1" "50" "22" "42522752" "42522752" "subst" "0" "00006" "CYP2D6_000248" "g.42522752G>A" "" "{PMID:Qian 2013:24192122}" "" "4041C>T (R440C)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42126750G>A" "" "VUS" "" "0000150876" "1" "50" "22" "42523591" "42523591" "subst" "1.62739E-5" "00006" "CYP2D6_000249" "g.42523591C>T" "" "{PMID:Qian 2013:24192122}" "" "3202G>A (R344Q)" "no haplotype assigned yet" "Germline" "" "rs76088846" "0" "" "" "g.42127589C>T" "" "VUS" "" "0000150877" "1" "50" "22" "42523598" "42523598" "subst" "4.06726E-6" "00006" "CYP2D6_000250" "g.42523598C>T" "" "{PMID:Qian 2013:24192122}" "" "3195G>A (V342M)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42127596C>T" "" "VUS" "" "0000150878" "1" "50" "22" "42523616" "42523616" "subst" "4.06928E-6" "00006" "CYP2D6_000251" "g.42523616C>T" "" "{PMID:Qian 2013:24192122}" "" "3177G>A (D336N)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42127614C>T" "" "VUS" "" "0000150879" "1" "50" "22" "42523850" "42523850" "subst" "0" "00006" "CYP2D6_000252" "g.42523850C>T" "" "{PMID:Qian 2013:24192122}" "" "2943G>A (V327M)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42127848C>T" "" "VUS" "" "0000150880" "1" "50" "22" "42524796" "42524796" "subst" "4.95737E-5" "00006" "CYP2D6_000253" "g.42524796A>G" "" "{PMID:Qian 2013:24192122}" "" "1997T>C (F219S)" "no haplotype assigned yet" "Germline" "" "rs371793722" "0" "" "" "g.42128794A>G" "" "VUS" "" "0000150881" "0" "50" "22" "42524809" "42524809" "subst" "2.4854E-5" "00006" "CYP2D6_000254" "g.42524809C>T" "" "{PMID:Qian 2013:24192122}" "" "1984G>A (E215K)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42128807C>T" "" "VUS" "" "0000150882" "1" "50" "22" "42525048" "42525048" "subst" "0" "00006" "CYP2D6_000255" "g.42525048G>C" "" "{PMID:Qian 2013:24192122}" "" "1745C>G (F164L)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42129046G>C" "" "VUS" "" "0000150883" "1" "50" "22" "42526720" "42526720" "subst" "0" "00006" "CYP2D6_000256" "g.42526720C>T" "" "{PMID:Qian 2013:24192122}" "" "74G>A (R25Q)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42130718C>T" "" "VUS" "" "0000150884" "1" "50" "22" "42523975" "42523975" "subst" "0.000203459" "00006" "CYP2D6_000257" "g.42523975T>C" "" "{PMID:Fuselli 2010:20520586}" "" "2818A>G (N285S)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42127973T>C" "" "VUS" "" "0000150885" "1" "50" "22" "42522619" "42522619" "subst" "0" "00006" "CYP2D6_000258" "g.42522619A>C" "" "{PMID:Fuselli 2010:20520586}" "" "4174T>G (L484R)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42126617A>C" "" "VUS" "" "0000150886" "1" "50" "22" "42523613" "42523613" "subst" "0.00458212" "00006" "CYP2D6_000147" "g.42523613C>T" "" "{PMID:Fuselli 2010:20520586}" "" "3180G>A (D337N)" "no haplotype assigned yet" "Germline" "" "rs78209835" "0" "" "" "g.42127611C>T" "" "VUS" "" "0000150887" "1" "50" "22" "42522617" "42522617" "subst" "4.54643E-5" "00006" "CYP2D6_000259" "g.42522617C>G" "" "{PMID:Fuselli 2010:20520586}" "" "4176G>C (V485L)" "no haplotype assigned yet" "Germline" "" "rs147943410" "0" "" "" "g.42126615C>G" "" "VUS" "" "0000150888" "1" "50" "22" "42522710" "42522710" "subst" "0" "00006" "CYP2D6_000260" "g.42522710A>C" "" "{PMID:Fuselli 2010:20520586}" "" "4083T>G (F454V)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42126708A>C" "" "VUS" "" "0000150889" "1" "50" "22" "42523633" "42523633" "subst" "0.000341925" "00006" "CYP2D6_000261" "g.42523633C>G" "" "{PMID:Contreras 2011:21391885}" "" "3160G>C (R330P)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42127631C>G" "" "VUS" "" "0000150890" "1" "50" "22" "42522724" "42522724" "subst" "0.00545352" "00006" "CYP2D6_000262" "g.42522724G>T" "" "{PMID:Contreras 2011:21391885}" "" "4069C>A (A449D)" "no haplotype assigned yet; variant found on CYP2D6*4 background" "Germline" "" "rs79392742" "0" "" "" "g.42126722G>T" "" "VUS" "" "0000150891" "1" "50" "22" "42524341" "42524341" "subst" "0.000297311" "00006" "CYP2D6_000263" "g.42524341A>G" "" "{PMID:Wright 2010:20597905}" "" "2452T>C" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42128339A>G" "" "VUS" "" "0000150892" "1" "50" "22" "42522736" "42522736" "subst" "0" "00006" "CYP2D6_000264" "g.42522736C>T" "" "{PMID:Matimba 2009:19164093}" "" "4057 G>A (G445E)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42126734C>T" "" "VUS" "" "0000150893" "1" "50" "22" "42525172" "42525172" "subst" "4.19347E-6" "00006" "CYP2D6_000265" "g.42525172C>A" "" "{PMID:Matimba 2009:19164093}" "" "1621G>T (R123L)" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42129170C>A" "" "VUS" "" "0000150894" "1" "50" "22" "42524183" "42524183" "subst" "0.00234546" "00006" "CYP2D6_000101" "g.42524183A>T" "" "Tandon, in preparation" "" "2610T>A (M279) (ex5 conversion)" "no haplotype assigned yet; gene conversion to CYP2D7 exon 5 (2470-2610)" "Germline" "" "rs1135828" "0" "" "" "g.42128181A>T" "" "VUS" "" "0000150895" "1" "50" "22" "42524323" "42524323" "subst" "0.00661735" "00006" "CYP2D6_000041" "g.42524323A>G" "" "Tandon, in preparation" "" "2470T>C (ex5 conversion)" "no haplotype assigned yet; gene conversion to CYP2D7 exon 5 (2470-2610)" "Germline" "" "" "0" "" "" "g.42128321A>G" "" "VUS" "" "0000150896" "1" "50" "22" "42524218" "42524218" "subst" "0.00765363" "00006" "CYP2D6_000038" "g.42524218G>T" "" "Tandon, in preparation" "" "2575C>A (ex5 conversion)" "no haplotype assigned yet; gene conversion to CYP2D7 exon 5 (2470-2610)" "Germline" "" "" "0" "" "" "g.42128216G>T" "" "VUS" "" "0000150897" "1" "50" "22" "42524187" "42524187" "subst" "0.000940402" "00006" "CYP2D6_000193" "g.42524187C>T" "" "Tandon, in preparation" "" "2606G>A (E278K) (ex5 conversion)" "no haplotype assigned yet; gene conversion to CYP2D7 exon 5 (2470-2610)" "Germline" "" "rs77913725" "0" "" "" "g.42128185C>T" "" "VUS" "" "0000150898" "1" "50" "22" "42524327" "42524327" "subst" "0.000171166" "00006" "CYP2D6_000266" "g.42524327A>G" "" "Tandon, in preparation" "" "2466T>C (L231P)" "no haplotype assigned yet" "Germline" "" "rs17002853" "0" "" "" "g.42128325A>G" "" "VUS" "" "0000150899" "1" "50" "22" "42522638" "42522638" "subst" "0" "00006" "CYP2D6_000267" "g.42522638G>A" "" "{PMID:Solus 2004:15469410}" "" "4155C>T (H478Y)" "no haplotype assigned yet" "Germline" "" "rs28371735" "0" "" "" "g.42126636G>A" "" "VUS" "" "0000150900" "1" "11" "22" "42522621" "42522621" "subst" "0" "00006" "CYP2D6_000189" "g.42522621G>A" "" "{PMID:Solus 2004:15469410}" "" "4172C>T" "no haplotype assigned yet" "Germline" "" "rs28371736" "0" "" "" "g.42126619G>A" "" "benign" "" "0000150901" "1" "11" "22" "42523358" "42523358" "subst" "0" "00006" "CYP2D6_000068" "g.42523358G>T" "" "{PMID:Solus 2004:15469410}" "" "3435C>A" "no haplotype assigned yet" "Germline" "" "rs28371729" "0" "" "" "g.42127356G>T" "" "benign" "" "0000150902" "1" "33" "22" "42524490" "42524490" "subst" "0" "00006" "CYP2D6_000106" "g.42524490G>A" "" "{PMID:Solus 2004:15469410}" "" "2303C>T" "no haplotype assigned yet" "Germline" "" "rs79738337" "0" "" "" "g.42128488G>A" "" "likely benign" "" "0000150903" "1" "50" "22" "42526891" "42526891" "subst" "0" "00006" "CYP2D6_000268" "g.42526891G>A" "" "{PMID:Solus 2004:15469410}" "" "-98C>T" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42130889G>A" "" "VUS" "" "0000150904" "1" "50" "22" "42526841" "42526841" "dup" "0" "00006" "CYP2D6_000269" "g.42526841dup" "" "{PMID:Solus 2004:15469410}" "" "-43insG" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42130839dup" "" "VUS" "" "0000150905" "1" "50" "22" "42524870" "42524870" "subst" "6.1626E-5" "00006" "CYP2D6_000270" "g.42524870G>A" "" "{PMID:Solus 2004:15469410}" "" "1923C>T" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42128868G>A" "" "VUS" "" "0000150906" "1" "50" "22" "42524795" "42524795" "subst" "0" "00006" "CYP2D6_000271" "g.42524795A>G" "" "{PMID:Solus 2004:15469410}" "" "1998T>C" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42128793A>G" "" "VUS" "" "0000150907" "1" "50" "22" "42524130" "42524130" "subst" "0.00348225" "00006" "CYP2D6_000272" "g.42524130C>T" "" "{PMID:Solus 2004:15469410}" "" "2663G>A" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42128128C>T" "" "VUS" "" "0000150908" "1" "50" "22" "42524033" "42524033" "subst" "0.000486457" "00006" "CYP2D6_000273" "g.42524033A>T" "" "{PMID:Solus 2004:15469410}" "" "2760T>A" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42128031A>T" "" "VUS" "" "0000150909" "1" "50" "22" "42523385" "42523385" "subst" "0" "00006" "CYP2D6_000274" "g.42523385A>G" "" "{PMID:Solus 2004:15469410}" "" "3408T>C" "no haplotype assigned yet" "Germline" "" "" "0" "" "" "g.42127383A>G" "" "VUS" "" "0000150910" "1" "50" "22" "42524743" "42524743" "subst" "0" "00006" "CYP2D6_000275" "g.42524743G>A" "" "Tandon, in preparation" "" "2050C>T (4i conversion)" "no haplotype assigned yet; gene conversion to CYP2D7 intron 4 (2050-2392)" "Germline" "" "" "0" "" "" "g.42128741G>A" "" "VUS" "" "0000150911" "1" "50" "22" "42524401" "42524401" "subst" "0" "00006" "CYP2D6_000276" "g.42524401C>T" "" "Tandon, in preparation" "" "2392G>A (4i conversion)" "no haplotype assigned yet; gene conversion to CYP2D7 intron 4 (2050-2392)" "Germline" "" "" "0" "" "" "g.42128399C>T" "" "VUS" "" "0000150912" "1" "50" "22" "42524401" "42524743" "" "0" "00006" "CYP2D6_000277" "g.42524401_42524743con42538103_42538446" "" "Tandon, in preparation" "" "4i conversion" "no haplotype assigned yet; gene conversion to CYP2D7 intron 4 (2050-2392)" "Germline" "" "" "0" "" "" "" "" "VUS" "" "0000150913" "1" "11" "22" "42525132" "42525132" "" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Broly 1995:08530011}" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000150914" "1" "11" "22" "42523943" "42523943" "" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Broly 1995:08530011}" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000150915" "1" "11" "22" "42522613" "42522613" "" "0" "00006" "CYP2D6_000010" "g.42522613=" "" "{PMID:Broly 1995:08530011}" "" "4180G>C" "" "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000150916" "2" "99" "22" "42522575" "42526794" "" "0" "00006" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "{PMID:Broly 1995:08530011}" "" "CYP2D6 deletion" "no CYP2D6 activity" "Germline" "" "" "0" "" "" "" "" "pathogenic" "" "0000150936" "3" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Toscano 2006:17001295}" "" "1661G>C" "" "Germline" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "benign" "" "0000150937" "3" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Toscano 2006:17001295}" "" "2850C>T" "" "Germline" "" "rs16947" "0" "" "" "g.42127941G>A" "" "benign" "" "0000150938" "3" "99" "22" "42523805" "42523805" "subst" "0.0804508" "00006" "CYP2D6_000025" "g.42523805C>T" "" "{PMID:Toscano 2006:17001295}" "" "2988G>A (spl)" "decreased activity (altered splicing, per allele 2.5-fold reduced protein levels)" "Germline" "" "rs28371725" "0" "" "" "g.42127803C>T" "" "pathogenic" "" "0000150939" "3" "30" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Toscano 2006:17001295}" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "rs1135840" "0" "" "" "" "" "likely benign" "" "0000150940" "3" "11" "22" "42528028" "42528028" "subst" "0" "00006" "CYP2D6_000026" "g.42528028=" "" "{PMID:Toscano 2006:17001295}" "" "-1235A>G" "" "Germline" "" "" "0" "" "" "" "" "benign" "" "0000150941" "3" "11" "22" "42527533" "42527533" "subst" "0" "00006" "CYP2D6_000027" "g.42527533G=" "" "{PMID:Toscano 2006:17001295}" "" "-740C>T" "Variant Error [EREF/ERANGE]: This genomic variant does not match the reference sequence; the transcript variant also has an error. Please fix this entry and then remove this message." "Germline" "" "rs28624811" "0" "" "" "" "" "benign" "" "0000150942" "3" "11" "22" "42527471" "42527471" "subst" "0" "00006" "CYP2D6_000028" "g.42527471=" "" "{PMID:Toscano 2006:17001295}" "" "-678G>A" "" "Germline" "" "rs28633410" "0" "" "" "g.42131469C>T" "" "benign" "" "0000150943" "3" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "{PMID:Toscano 2006:17001295}" "" "245A= (1i conversion)" "" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000150944" "3" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "{PMID:Toscano 2006:17001295}" "" "232G=; 233A= (1i conversion)" "" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000150945" "3" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "{PMID:Toscano 2006:17001295}" "" "227T= (1i conversion)" "" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000150946" "3" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "{PMID:Toscano 2006:17001295}" "" "223C= (1i conversion)" "" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000150947" "3" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "{PMID:Toscano 2006:17001295}" "" "221C= (1i conversion)" "" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000150948" "3" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "{PMID:Toscano 2006:17001295}" "" "214G= (1i conversion)" "" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000150949" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A= (1i conversion)" "reference haplotype CYP2D6*41" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000150950" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G=; 233A= (1i conversion)" "reference haplotype CYP2D6*41" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000150951" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T= (1i conversion)" "reference haplotype CYP2D6*41" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000150952" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C= (1i conversion)" "reference haplotype CYP2D6*41" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000150953" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C= (1i conversion)" "reference haplotype CYP2D6*41" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000150954" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G= (1i conversion)" "reference haplotype CYP2D6*41" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000164289" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P34S" "cDNA expression cloning in COS-7 cells shows reduced (0.5) protein expression and low (0.1) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164290" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.5) protein expression and low (0.1) enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164291" "1" "99" "22" "42522660" "42522668" "dup" "0" "00006" "CYP2D6_000074" "g.42522660_42522668dup" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "4125_4133insGTGCCCACT" "cDNA expression cloning in COS-7 cells shows reduced (0.8) protein expression and reduced (0.4) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126658_42126666dup" "" "NA" "" "0000164292" "1" "50" "22" "42522940" "42522940" "subst" "0" "00006" "CYP2D6_000082" "g.42522940C>T" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "E410K" "cDNA expression cloning in COS-7 cells shows reduced (0.8) protein expression and normal enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126938C>T" "" "NA" "" "0000164293" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P34S" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164294" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164295" "1" "50" "22" "42522662" "42522663" "delins" "0" "00006" "CYP2D6_000182" "g.42522662_42522663delinsGC" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P469A (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126660_42126661delinsGC" "" "NA" "" "0000164296" "1" "50" "22" "42522662" "42522662" "subst" "7.0729E-5" "00006" "CYP2D6_000183" "g.42522662T>C" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "T470A (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126660T>C" "" "NA" "" "0000164297" "1" "50" "22" "42522637" "42522638" "delins" "0" "00006" "CYP2D6_000185" "g.42522637_42522638delinsGA" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "H478S (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126635_42126636delinsGA" "" "NA" "" "0000164298" "1" "50" "22" "42522635" "42522635" "subst" "0" "00006" "CYP2D6_000186" "g.42522635C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "G479R (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126633C>G" "" "NA" "" "0000164299" "1" "50" "22" "42522629" "42522629" "subst" "0" "00006" "CYP2D6_000187" "g.42522629A>C" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "F481V (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126627A>C" "" "NA" "" "0000164300" "1" "50" "22" "42522624" "42522627" "delins" "0" "00006" "CYP2D6_000188" "g.42522624_42522627delinsGCTG" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "A482S (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126622_42126625delinsGCTG" "" "NA" "" "0000164301" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and increased (1.5) enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164302" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P34S" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164303" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164304" "1" "50" "22" "42526721" "42526721" "subst" "0" "00006" "CYP2D6_000121" "g.42526721G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "R25W" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42130719G>A" "" "NA" "" "0000164305" "1" "30" "22" "42525823" "42525823" "subst" "0" "00006" "CYP2D6_000093" "g.42525823G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "A90V" "cDNA expression cloning in COS-7 cells shows normal protein expression and normal enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42129821G>A" "" "NA" "" "0000164306" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P34S" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.4) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164307" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.4) enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164308" "1" "50" "22" "42525182" "42525182" "subst" "0.001645" "00006" "CYP2D6_000122" "g.42525182A>T" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "F120I" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.4) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42129180A>T" "" "NA" "" "0000164309" "1" "99" "22" "42525073" "42525073" "subst" "2.51722E-5" "00006" "CYP2D6_000094" "g.42525073T>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "E156A" "cDNA expression cloning in COS-7 cells shows reduced (0.5) protein expression and reduced (0.2) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42129071T>G" "" "NA" "" "0000164310" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "R296C" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.1) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42127941G>A" "" "NA" "" "0000164311" "1" "50" "22" "42523621" "42523621" "subst" "0" "00006" "CYP2D6_000148" "g.42523621T>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "E334A" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.1) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42127619T>G" "" "NA" "" "0000164312" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.1) enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164313" "1" "50" "22" "42525182" "42525182" "subst" "0.001645" "00006" "CYP2D6_000122" "g.42525182A>T" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "F120I" "cDNA expression cloning in COS-7 cells shows reduced (0.5) protein expression and high (1-2.0) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42129180A>T" "" "NA" "" "0000164314" "1" "50" "22" "42525176" "42525176" "subst" "0.000795803" "00006" "CYP2D6_000151" "g.42525176C>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "A122S" "cDNA expression cloning in COS-7 cells shows reduced (0.5) protein expression and high (1-2.0) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42129174C>A" "" "NA" "" "0000164315" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P34S" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.1) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164316" "1" "50" "22" "42524237" "42524237" "subst" "5.73399E-5" "00006" "CYP2D6_000152" "g.42524237G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "T261I" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.1) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42128235G>A" "" "NA" "" "0000164317" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and reduced (0.1) enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164318" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "R296C" "cDNA expression cloning in COS-7 cells shows reduced (0.3) protein expression and reduced (0.5) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42127941G>A" "" "NA" "" "0000164319" "1" "50" "22" "42522958" "42522958" "subst" "0" "00006" "CYP2D6_000159" "g.42522958T>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "K404Q" "cDNA expression cloning in COS-7 cells shows reduced (0.3) protein expression and reduced (0.5) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126956T>G" "" "NA" "" "0000164320" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.3) protein expression and reduced (0.5) enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164321" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P34S" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164322" "1" "50" "22" "42525908" "42525908" "subst" "2.93738E-5" "00006" "CYP2D6_000161" "g.42525908G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "R62W" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42129906G>A" "" "NA" "" "0000164323" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164324" "1" "50" "22" "42522662" "42522663" "delins" "0" "00006" "CYP2D6_000182" "g.42522662_42522663delinsGC" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P469A (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126660_42126661delinsGC" "" "NA" "" "0000164325" "1" "50" "22" "42522662" "42522662" "subst" "7.0729E-5" "00006" "CYP2D6_000183" "g.42522662T>C" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "T470A (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126660T>C" "" "NA" "" "0000164326" "1" "50" "22" "42522637" "42522638" "delins" "0" "00006" "CYP2D6_000185" "g.42522637_42522638delinsGA" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "H478S (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126635_42126636delinsGA" "" "NA" "" "0000164327" "1" "50" "22" "42522635" "42522635" "subst" "0" "00006" "CYP2D6_000186" "g.42522635C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "G479R (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126633C>G" "" "NA" "" "0000164328" "1" "50" "22" "42522629" "42522629" "subst" "0" "00006" "CYP2D6_000187" "g.42522629A>C" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "F481V (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126627A>C" "" "NA" "" "0000164329" "1" "50" "22" "42522624" "42522627" "delins" "0" "00006" "CYP2D6_000188" "g.42522624_42522627delinsGCTG" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "A482S (con ex9)" "cDNA expression cloning in COS-7 cells shows reduced (0.4) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42126622_42126625delinsGCTG" "" "NA" "" "0000164330" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "P34S" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164331" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "R296C" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42127941G>A" "" "NA" "" "0000164332" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164333" "1" "99" "22" "42525035" "42525035" "subst" "0.000960713" "00006" "CYP2D6_000072" "g.42525035C>T" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "G169R" "cDNA expression cloning in COS-7 cells shows reduced (0.6) protein expression and no enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42129033C>T" "" "NA" "" "0000164334" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "R296C" "cDNA expression cloning in COS-7 cells shows reduced (0.8) protein expression and reduced (0.7) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42127941G>A" "" "NA" "" "0000164335" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "S486T" "cDNA expression cloning in COS-7 cells shows reduced (0.8) protein expression and reduced (0.7) enzymatic activity for bufuralol and dextromethorphan\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164337" "1" "99" "22" "42525035" "42525035" "subst" "0.000960713" "00006" "CYP2D6_000072" "g.42525035C>T" "" "{PMID:Sakuyama 2008:18784265}, {DOI:Sakuyama 2008:10.1124/dmd.108.023242}" "" "G169R" "cDNA expression cloning in COS-7 cells shows reduced (0.8) protein expression and reduced (0.7) enzymatic activity for bufuralol and dextromethorphan" "In vitro (cloned)" "" "" "0" "" "" "g.42129033C>T" "" "NA" "" "0000164338" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Matsunaga 2009:19158312}, {DOI:Matsunaga 2009:10.1124/dmd.108.026096}" "" "P34S" "protein from cDNA expression cloning inE.coli shows reduced (0.03) dextromethorphan O-demethylation" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164339" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Matsunaga 2009:19158312}, {DOI:Matsunaga 2009:10.1124/dmd.108.026096}" "" "S486T" "protein from cDNA expression cloning inE.coli shows reduced (0.03) dextromethorphan O-demethylation\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164340" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Matsunaga 2009:19158312}, {DOI:Matsunaga 2009:10.1124/dmd.108.026096}" "" "P34S" "protein from cDNA expression cloning inE.coli shows reduced (0.005) dextromethorphan O-demethylation" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164341" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Matsunaga 2009:19158312}, {DOI:Matsunaga 2009:10.1124/dmd.108.026096}" "" "S486T" "protein from cDNA expression cloning inE.coli shows reduced (0.005) dextromethorphan O-demethylation\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164342" "1" "70" "22" "42525182" "42525182" "subst" "0.001645" "00006" "CYP2D6_000122" "g.42525182A>T" "" "{PMID:Matsunaga 2009:19158312}, {DOI:Matsunaga 2009:10.1124/dmd.108.026096}" "" "F120I" "protein from cDNA expression cloning inE.coli shows reduced (0.005) dextromethorphan O-demethylation" "In vitro (cloned)" "" "" "0" "" "" "g.42129180A>T" "" "NA" "" "0000164343" "1" "99" "22" "42526694" "42526694" "subst" "0.206804" "00006" "CYP2D6_000009" "g.42526694G>A" "" "{PMID:Matsunaga 2009:19158312}, {DOI:Matsunaga 2009:10.1124/dmd.108.026096}" "" "P34S" "protein from cDNA expression cloning inE.coli shows reduced (0.01) dextromethorphan O-demethylation" "In vitro (cloned)" "" "" "0" "" "" "g.42130692G>A" "" "NA" "" "0000164344" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Matsunaga 2009:19158312}, {DOI:Matsunaga 2009:10.1124/dmd.108.026096}" "" "S486T" "protein from cDNA expression cloning inE.coli shows reduced (0.01) dextromethorphan O-demethylation\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "" "0" "" "" "" "" "NA" "" "0000164345" "1" "70" "22" "42525182" "42525182" "subst" "0.001645" "00006" "CYP2D6_000122" "g.42525182A>T" "" "{PMID:Matsunaga 2009:19158312}, {DOI:Matsunaga 2009:10.1124/dmd.108.026096}" "" "F120I" "protein from cDNA expression cloning inE.coli shows reduced (0.01) dextromethorphan O-demethylation" "In vitro (cloned)" "" "" "0" "" "" "g.42129180A>T" "" "NA" "" "0000164346" "1" "99" "22" "42522749" "42522749" "subst" "0.000178924" "00006" "CYP2D6_000104" "g.42522749G>A" "" "{PMID:Klein 2007:17460029}, {DOI:Klein 2007:10.1124/dmd.107.015149}" "" "R441C" "cDNA expression cloning in insect/COS-1 cells shows normal protein expression and no enzymatic activity for propafenone" "In vitro (cloned)" "" "" "0" "" "" "g.42126747G>A" "" "NA" "" "0000164352" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A= (1i conversion)" "reference haplotype CYP2D6*59 (*2J)" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000164353" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G=; 233A= (1i conversion)" "reference haplotype CYP2D6*59 (*2J)" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000164354" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T= (1i conversion)" "reference haplotype CYP2D6*59 (*2J)" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000164355" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C= (1i conversion)" "reference haplotype CYP2D6*59 (*2J)" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000164356" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C= (1i conversion)" "reference haplotype CYP2D6*59 (*2J)" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000164357" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G= (1i conversion)" "reference haplotype CYP2D6*59 (*2J)" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000164359" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A= (1i conversion)" "reference haplotype CYP2D6*2M" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000164360" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G=; 233A= (1i conversion)" "reference haplotype CYP2D6*2M" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000164361" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T= (1i conversion)" "reference haplotype CYP2D6*2M" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000164362" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C= (1i conversion)" "reference haplotype CYP2D6*2M" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000164363" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C= (1i conversion)" "reference haplotype CYP2D6*2M" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000164364" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G= (1i conversion)" "reference haplotype CYP2D6*2M" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000164365" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A= (1i conversion)" "reference haplotype CYP2D6*2A" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000164366" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G=; 233A= (1i conversion)" "reference haplotype CYP2D6*2A" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000164367" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T= (1i conversion)" "reference haplotype CYP2D6*2A" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000164368" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C= (1i conversion)" "reference haplotype CYP2D6*2A" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000164369" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C= (1i conversion)" "reference haplotype CYP2D6*2A" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000164370" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G= (1i conversion)" "reference haplotype CYP2D6*2A" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000164371" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A= (1i conversion)" "reference haplotype CYP2D6*31" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000164372" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G=; 233A= (1i conversion)" "reference haplotype CYP2D6*31" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000164373" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T= (1i conversion)" "reference haplotype CYP2D6*31" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000164374" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C= (1i conversion)" "reference haplotype CYP2D6*31" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000164375" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C= (1i conversion)" "reference haplotype CYP2D6*31" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000164376" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G= (1i conversion)" "reference haplotype CYP2D6*31" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000164377" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "245A= (1i conversion)" "reference haplotype CYP2D6*14B" "Germline" "" "rs1081000" "0" "" "" "g.42130547=" "" "benign" "" "0000164378" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "232G=; 233A= (1i conversion)" "reference haplotype CYP2D6*14B" "Germline" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "benign" "" "0000164379" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "227T= (1i conversion)" "reference haplotype CYP2D6*14B" "Germline" "" "rs76312385" "0" "" "" "g.42130565=" "" "benign" "" "0000164380" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "223C= (1i conversion)" "reference haplotype CYP2D6*14B" "Germline" "" "rs74644586" "0" "" "" "g.42130569=" "" "benign" "" "0000164381" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "221C= (1i conversion)" "reference haplotype CYP2D6*14B" "Germline" "" "rs1080996" "0" "" "" "g.42130571=" "" "benign" "" "0000164382" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "Reference haplotype - Human P450 (CYP) Allele Nomenclature Committee" "" "214G= (1i conversion)" "reference haplotype CYP2D6*14B" "Germline" "" "rs1080995" "0" "" "" "g.42130578=" "" "benign" "" "0000164383" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "1661G>C" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "NA" "" "0000164384" "1" "11" "22" "42523854" "42523854" "subst" "0.00291774" "00006" "CYP2D6_000045" "g.42523854C>T" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "2291G>A" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs267608300" "0" "" "" "g.42127852C>T" "" "NA" "" "0000164385" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "2850C>T" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs16947" "0" "" "" "g.42127941G>A" "" "NA" "" "0000164386" "1" "99" "22" "42523854" "42523854" "subst" "0.00291774" "00006" "CYP2D6_000045" "g.42523854C>T" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "2939G>A" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs79292917" "0" "" "" "g.42127852C>T" "" "NA" "" "0000164387" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "4180G>C" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "rs1135840" "0" "" "" "" "" "NA" "" "0000164388" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "245A= (1i conversion)" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs1081000" "0" "" "" "g.42130547=" "" "NA" "" "0000164389" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "232G=; 233A= (1i conversion)" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "NA" "" "0000164390" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "227T= (1i conversion)" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs76312385" "0" "" "" "g.42130565=" "" "NA" "" "0000164391" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "223C= (1i conversion)" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs74644586" "0" "" "" "g.42130569=" "" "NA" "" "0000164392" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "221C= (1i conversion)" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs1080996" "0" "" "" "g.42130571=" "" "NA" "" "0000164393" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "214G= (1i conversion)" "gene expression cloning Huh7 hepatoma cells shows reduced (0.37) protein expression and reduced (0.30) propafenone activity" "In vitro (cloned)" "" "rs1080995" "0" "" "" "g.42130578=" "" "NA" "" "0000164394" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "1661G>C" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "NA" "" "0000164396" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "2850C>T" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs16947" "0" "" "" "g.42127941G>A" "" "NA" "" "0000164397" "1" "99" "22" "42523854" "42523854" "subst" "0.00291774" "00006" "CYP2D6_000045" "g.42523854C>T" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "2939G>A" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs79292917" "0" "" "" "g.42127852C>T" "" "NA" "" "0000164398" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "4180G>C" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "rs1135840" "0" "" "" "" "" "NA" "" "0000164399" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "245A= (1i conversion)" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs1081000" "0" "" "" "g.42130547=" "" "NA" "" "0000164400" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "232G=; 233A= (1i conversion)" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "NA" "" "0000164401" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "227T= (1i conversion)" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs76312385" "0" "" "" "g.42130565=" "" "NA" "" "0000164402" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "223C= (1i conversion)" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs74644586" "0" "" "" "g.42130569=" "" "NA" "" "0000164403" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "221C= (1i conversion)" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs1080996" "0" "" "" "g.42130571=" "" "NA" "" "0000164404" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "214G= (1i conversion)" "allele *2J1 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs1080995" "0" "" "" "g.42130578=" "" "NA" "" "0000164405" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "1661G>C" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "NA" "" "0000164406" "1" "11" "22" "42523854" "42523854" "subst" "0.00291774" "00006" "CYP2D6_000045" "g.42523854C>T" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "2291G>A" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs267608300" "0" "" "" "g.42127852C>T" "" "NA" "" "0000164407" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "2850C>T" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs16947" "0" "" "" "g.42127941G>A" "" "NA" "" "0000164409" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "4180G>C" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "rs1135840" "0" "" "" "" "" "NA" "" "0000164410" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "245A= (1i conversion)" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs1081000" "0" "" "" "g.42130547=" "" "NA" "" "0000164411" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "232G=; 233A= (1i conversion)" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "NA" "" "0000164412" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "227T= (1i conversion)" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs76312385" "0" "" "" "g.42130565=" "" "NA" "" "0000164413" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "223C= (1i conversion)" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs74644586" "0" "" "" "g.42130569=" "" "NA" "" "0000164414" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "221C= (1i conversion)" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs1080996" "0" "" "" "g.42130571=" "" "NA" "" "0000164415" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "214G= (1i conversion)" "allele *2J2 - gene expression cloning Huh7 hepatoma cells shows reduced (0.35) protein expression and reduced (0.4) propafenone activity" "In vitro (cloned)" "" "rs1080995" "0" "" "" "g.42130578=" "" "NA" "" "0000164416" "1" "11" "22" "42525132" "42525132" "subst" "0" "00006" "CYP2D6_000011" "g.42525132=" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "1661G>C" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity" "In vitro (cloned)" "" "rs1058164" "0" "" "" "g.42129130C>G" "" "NA" "" "0000164418" "1" "11" "22" "42523943" "42523943" "subst" "0" "00006" "CYP2D6_000012" "g.42523943=" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "2850C>T" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity" "In vitro (cloned)" "" "rs16947" "0" "" "" "g.42127941G>A" "" "NA" "" "0000164420" "1" "11" "22" "42522613" "42522613" "subst" "0" "00006" "CYP2D6_000010" "g.42522613C>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "4180G>C" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity\r\nVariant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "In vitro (cloned)" "" "rs1135840" "0" "" "" "" "" "NA" "" "0000164421" "1" "11" "22" "42526549" "42526549" "subst" "0" "00006" "CYP2D6_000229" "g.42526549C>T" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "245A= (1i conversion)" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity" "In vitro (cloned)" "" "rs1081000" "0" "" "" "g.42130547=" "" "NA" "" "0000164422" "1" "11" "22" "42526561" "42526562" "delins" "0" "00006" "CYP2D6_000228" "g.42526561_42526562delinsTC" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "232G=; 233A= (1i conversion)" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity" "In vitro (cloned)" "" "rs796532118" "0" "" "" "g.42130559_42130560=" "" "NA" "" "0000164423" "1" "11" "22" "42526567" "42526567" "subst" "0.662699" "00006" "CYP2D6_000227" "g.42526567G>A" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "227T= (1i conversion)" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity" "In vitro (cloned)" "" "rs76312385" "0" "" "" "g.42130565=" "" "NA" "" "0000164424" "1" "11" "22" "42526571" "42526571" "subst" "0.662701" "00006" "CYP2D6_000226" "g.42526571C>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "223C= (1i conversion)" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity" "In vitro (cloned)" "" "rs74644586" "0" "" "" "g.42130569=" "" "NA" "" "0000164425" "1" "11" "22" "42526573" "42526573" "subst" "0.6621" "00006" "CYP2D6_000225" "g.42526573T>G" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "221C= (1i conversion)" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity" "In vitro (cloned)" "" "rs1080996" "0" "" "" "g.42130571=" "" "NA" "" "0000164426" "1" "11" "22" "42526580" "42526580" "subst" "0.664997" "00006" "CYP2D6_000224" "g.42526580G>C" "" "{PMID:Toscano 2006:17001296}, {DOI:Toscano 2006:10.1097/01.fpc.0000236331.03681.24}" "" "214G= (1i conversion)" "allele *2J - gene expression cloning Huh7 hepatoma cells shows increased (1.7) protein expression and increased (1.6) propafenone activity" "In vitro (cloned)" "" "rs1080995" "0" "" "" "g.42130578=" "" "NA" "" "0000329065" "0" "50" "22" "42524183" "42524183" "subst" "0.00234546" "01804" "CYP2D6_000101" "g.42524183A>T" "" "" "" "CYP2D6(NM_000106.5):c.836T>A (p.(Met279Lys))" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "0" "" "" "g.42128181A>T" "" "VUS" "" "0000440142" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440143" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440144" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440145" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440146" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440147" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440148" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440149" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440150" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440151" "0" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440152" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440153" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440154" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440155" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440156" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440157" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440158" "3" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "poor metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440159" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440160" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440161" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440162" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440163" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440164" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440165" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440166" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440167" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440168" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440169" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440170" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440171" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440172" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440173" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440174" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440175" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440176" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440177" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440178" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440179" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440180" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440181" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440182" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440183" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440184" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440185" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440186" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440187" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440188" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440189" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440190" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440191" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440192" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440193" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440194" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440195" "0" "90" "22" "42524244" "42524244" "del" "0.0123819" "02562" "CYP2D6_000016" "g.42524244del" "" "IP3 project, submitted" "" "2549delA" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128242del" "" "benign (!)" "" "0000440196" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440197" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440198" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440199" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440200" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440201" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440202" "3" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "poor metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440203" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440204" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440205" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440206" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440207" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440208" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440209" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440210" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440211" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440212" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440213" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440214" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440215" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440216" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440217" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440218" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440219" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440220" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440221" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440222" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440223" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440224" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440225" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440226" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440227" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440228" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440229" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440230" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440231" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440232" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440233" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440234" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440235" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440236" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440237" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440238" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440239" "0" "90" "22" "42522575" "42526794" "dup" "0" "02562" "CYP2D6_000279" "g.(?_42522575)_(42526794_?)dup" "" "IP3 project, submitted" "" "CN3" "ultra-rapid metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440240" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440241" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440242" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440243" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440244" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440245" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440246" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440247" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440248" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440249" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440250" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440251" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440252" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440253" "2" "90" "22" "42525086" "42525086" "del" "0.00791688" "02562" "CYP2D6_000017" "g.42525086del" "" "IP3 project, submitted" "" "1707delT" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42129084del" "" "benign (!)" "" "0000440254" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440255" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440256" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440257" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440258" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440259" "0" "90" "22" "42524244" "42524244" "del" "0.0123819" "02562" "CYP2D6_000016" "g.42524244del" "" "IP3 project, submitted" "" "2549delA" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128242del" "" "benign (!)" "" "0000440260" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440261" "0" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440262" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440263" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440264" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440265" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440266" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440267" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440268" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440269" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440270" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440271" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440272" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440273" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440274" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440275" "0" "90" "22" "42525086" "42525086" "del" "0.00791688" "02562" "CYP2D6_000017" "g.42525086del" "" "IP3 project, submitted" "" "1707delT" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42129084del" "" "benign (!)" "" "0000440276" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440277" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440278" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440279" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440280" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440281" "0" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440282" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440283" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440284" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440285" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440286" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440287" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440288" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440289" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440290" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440291" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440292" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440293" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440294" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440295" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440296" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440297" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440298" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440299" "2" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440300" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440301" "2" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440302" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440303" "2" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440304" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440305" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440306" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440307" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440308" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440309" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440310" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440311" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440312" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440313" "0" "90" "22" "42524244" "42524244" "del" "0.0123819" "02562" "CYP2D6_000016" "g.42524244del" "" "IP3 project, submitted" "" "2549delA" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128242del" "" "benign (!)" "" "0000440314" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440315" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440316" "3" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "poor metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440317" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440318" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440319" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440320" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440321" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440322" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440323" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440324" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440325" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440326" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440327" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440328" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440329" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440330" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440331" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440332" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440333" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440334" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440335" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440336" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440337" "0" "90" "22" "42524244" "42524244" "del" "0.0123819" "02562" "CYP2D6_000016" "g.42524244del" "" "IP3 project, submitted" "" "2549delA" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128242del" "" "benign (!)" "" "0000440338" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440339" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440340" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440341" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440342" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440343" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440344" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440345" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440346" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440347" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440348" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440349" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440350" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440351" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440352" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440353" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440354" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440355" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440356" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440357" "0" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440358" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440359" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440360" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440361" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440362" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440363" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440364" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440365" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440366" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440367" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440368" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440369" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440370" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440371" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440372" "0" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440373" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440374" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440375" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440376" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440377" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440378" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440379" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440380" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440381" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440382" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440383" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440384" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440385" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440386" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440387" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440388" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440389" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440390" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440391" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440392" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440393" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440394" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440395" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440396" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440397" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440398" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440399" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440400" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440401" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440402" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440403" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440404" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440405" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440406" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440407" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440408" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440409" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440410" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440411" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440412" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440413" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440414" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440415" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440416" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440417" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440418" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440419" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440420" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440421" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440422" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440423" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440424" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440425" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440426" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440427" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440428" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440429" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440430" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440431" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440432" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440433" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440434" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440435" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440436" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440437" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440438" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440439" "3" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "poor metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440440" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440441" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440442" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440443" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440444" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440445" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440446" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440447" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440448" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440449" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440450" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440451" "3" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "poor metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440452" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440453" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440454" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440455" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440456" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440457" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440458" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440459" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440460" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440461" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440462" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440463" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440464" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440465" "0" "90" "22" "42522575" "42526794" "dup" "0" "02562" "CYP2D6_000279" "g.(?_42522575)_(42526794_?)dup" "" "IP3 project, submitted" "" "CN3" "ultra-rapid metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440466" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440467" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440468" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440469" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440470" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440471" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440472" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440473" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440474" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440475" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440476" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440477" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440478" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440479" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440480" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440481" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440482" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440483" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440484" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440485" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440486" "0" "90" "22" "42522575" "42526794" "dup" "0" "02562" "CYP2D6_000279" "g.(?_42522575)_(42526794_?)dup" "" "IP3 project, submitted" "" "CN3" "ultra-rapid metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440487" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440488" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440489" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440490" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440491" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440492" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440493" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440494" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440495" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440496" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440497" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440498" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440499" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440500" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440501" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440502" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440503" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440504" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440505" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440506" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440507" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440508" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440509" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440510" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440511" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440512" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440513" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440514" "0" "90" "22" "42525086" "42525086" "del" "0.00791688" "02562" "CYP2D6_000017" "g.42525086del" "" "IP3 project, submitted" "" "1707delT" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42129084del" "" "benign (!)" "" "0000440515" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440516" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440517" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440518" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440519" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440520" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440521" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440522" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440523" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440524" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440525" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440526" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440527" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440528" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440529" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440530" "0" "90" "22" "42522575" "42526794" "dup" "0" "02562" "CYP2D6_000279" "g.(?_42522575)_(42526794_?)dup" "" "IP3 project, submitted" "" "CN3" "ultra-rapid metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440531" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440532" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440533" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440534" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440535" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440536" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440537" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440538" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440539" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440540" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440541" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440542" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440543" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440544" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440545" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440546" "0" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440547" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440548" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440549" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440550" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440551" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440552" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440553" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440554" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440555" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440556" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440557" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440558" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440559" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440560" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440561" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440562" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440563" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440564" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440565" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440566" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440567" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440568" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440569" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440570" "0" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440571" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440572" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440573" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440574" "0" "90" "22" "42525086" "42525086" "del" "0.00791688" "02562" "CYP2D6_000017" "g.42525086del" "" "IP3 project, submitted" "" "1707delT" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42129084del" "" "benign (!)" "" "0000440575" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440576" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440577" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440578" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440579" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440580" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440581" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440582" "0" "90" "22" "42524244" "42524244" "del" "0.0123819" "02562" "CYP2D6_000016" "g.42524244del" "" "IP3 project, submitted" "" "2549delA" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128242del" "" "benign (!)" "" "0000440583" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440584" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440585" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440586" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440587" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440588" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440589" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440590" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440591" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440592" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440593" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440594" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440595" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440596" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440597" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440598" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440599" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440600" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440601" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440602" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440603" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440604" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440605" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440606" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440607" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440608" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440609" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440610" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440611" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440612" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440613" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440614" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440615" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440616" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440617" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440618" "3" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "poor metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440619" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440620" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440621" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440622" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440623" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440624" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440625" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440626" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440627" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440628" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440629" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440630" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440631" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440632" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440633" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440634" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440635" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440636" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440637" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440638" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440639" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440640" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440641" "0" "90" "22" "42522575" "42526794" "dup" "0" "02562" "CYP2D6_000279" "g.(?_42522575)_(42526794_?)dup" "" "IP3 project, submitted" "" "CN3" "ultra-rapid metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440642" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440643" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440644" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440645" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440646" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440647" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440648" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440649" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440650" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440651" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440652" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440653" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440654" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440655" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440656" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440657" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440658" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440659" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440660" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440661" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440662" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440663" "2" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440664" "2" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440665" "2" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440666" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440667" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440668" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440669" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440670" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440671" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440672" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440673" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440674" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440675" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440676" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440677" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440678" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440679" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440680" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "poor metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440681" "2" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440682" "2" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440683" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440684" "0" "90" "22" "42522575" "42526794" "dup" "0" "02562" "CYP2D6_000279" "g.(?_42522575)_(42526794_?)dup" "" "IP3 project, submitted" "" "CN3" "ultra-rapid metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440685" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440686" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440687" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440688" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440689" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440690" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440691" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440692" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440693" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440694" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440695" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440696" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440697" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440698" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440699" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440700" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440701" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440702" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440703" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440704" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440705" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440706" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440707" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440708" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440709" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440710" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440711" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440712" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440713" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440714" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440715" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440716" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440717" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440718" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440719" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440720" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440721" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440722" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440723" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440724" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440725" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440726" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440727" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440728" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440729" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440730" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440731" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440732" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440733" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440734" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440735" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440736" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440737" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440738" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440739" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440740" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440741" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440742" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440743" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440744" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440745" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440746" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440747" "0" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440748" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440749" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440750" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440751" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440752" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440753" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440754" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440755" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440756" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440757" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440758" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440759" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440760" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440761" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440762" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440763" "1" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "intermediate metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440764" "2" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440765" "2" "90" "22" "42524178" "42524180" "del" "0" "02562" "CYP2D6_000014" "g.42524178_42524180del" "" "IP3 project, submitted" "" "2615delAAG" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42128176_42128178del" "" "benign (!)" "" "0000440766" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440767" "0" "90" "22" "42522575" "42526794" "dup" "0" "02562" "CYP2D6_000279" "g.(?_42522575)_(42526794_?)dup" "" "IP3 project, submitted" "" "CN3" "ultra-rapid metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440768" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440769" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440770" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440771" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440772" "3" "90" "22" "42522575" "42526794" "del" "0" "02562" "CYP2D6_000000" "g.(?_42522575)_(42526794_?)del" "" "IP3 project, submitted" "" "CN1" "poor metabolizer" "Germline" "" "" "0" "" "" "" "" "benign (!)" "" "0000440773" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440774" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440775" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440776" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440777" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440778" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440779" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440780" "0" "90" "22" "42525086" "42525086" "del" "0.00791688" "02562" "CYP2D6_000017" "g.42525086del" "" "IP3 project, submitted" "" "1707delT" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42129084del" "" "benign (!)" "" "0000440781" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440782" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440783" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440784" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440785" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440786" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440787" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440788" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440789" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440790" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440791" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440792" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440793" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440794" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440795" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440796" "0" "90" "22" "42524244" "42524244" "del" "0.0123819" "02562" "CYP2D6_000016" "g.42524244del" "" "IP3 project, submitted" "" "2549delA" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128242del" "" "benign (!)" "" "0000440797" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440798" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440799" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440800" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440801" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440802" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440803" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440804" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440805" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440806" "3" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440807" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440808" "3" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440809" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440810" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440811" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440812" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440813" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440814" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440815" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440816" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440817" "0" "90" "22" "42523805" "42523805" "subst" "0.0804508" "02562" "CYP2D6_000025" "g.42523805C>T" "" "IP3 project, submitted" "" "2988G>A (spl)" "extensive metabolizer" "Germline" "" "" "0" "" "" "g.42127803C>T" "" "benign (!)" "" "0000440818" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440819" "3" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440820" "3" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440821" "3" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "poor metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440822" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440823" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440824" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440825" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440826" "3" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440827" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440828" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440829" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440830" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000440831" "0" "10" "22" "42528382" "42528382" "subst" "0" "02562" "CYP2D6_000046" "g.42528382=" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42132375G>C" "" "benign" "" "0000440832" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440833" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440834" "0" "10" "22" "42523943" "42523943" "subst" "0" "02562" "CYP2D6_000012" "g.42523943=" "" "IP3 project, submitted" "" "2850C>T" "" "Germline" "" "" "0" "" "" "g.42127941G>A" "" "benign" "" "0000440835" "0" "10" "22" "42526694" "42526694" "subst" "0.206804" "02562" "CYP2D6_000009" "g.42526694G>A" "" "IP3 project, submitted" "" "" "" "Germline" "" "" "0" "" "" "g.42130692G>A" "" "benign" "" "0000440836" "0" "10" "22" "42522613" "42522613" "subst" "0" "02562" "CYP2D6_000010" "g.42522613C>G" "" "IP3 project, submitted" "" "4180G>C (S486T)" "Variant Error [EREF/EREF]: This genomic variant does not match the reference sequence; the transcript variant does not match the reference sequence either. Please fix this entry and then remove this message." "Germline" "" "" "0" "" "" "g.42126611C>G" "" "benign" "" "0000440837" "0" "10" "22" "42525132" "42525132" "subst" "0" "02562" "CYP2D6_000011" "g.42525132=" "" "IP3 project, submitted" "" "1661G>C" "" "Germline" "" "" "0" "" "" "g.42129130C>G" "" "benign" "" "0000440838" "0" "90" "22" "42524947" "42524947" "subst" "0.138444" "02562" "CYP2D6_000004" "g.42524947C>T" "" "IP3 project, submitted" "" "1846G>A (spl)" "intermediate metabolizer" "Germline" "" "" "0" "" "" "g.42128945C>T" "" "benign (!)" "" "0000650998" "1" "30" "22" "42523858" "42523858" "subst" "0.00133446" "03575" "CYP2D6_000018" "g.42523858T>G" "42/2793 individuals" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "" "" "42 heterozygous; {DB:CLININrs5030867}" "Germline" "" "rs5030867" "0" "" "" "g.42127856T>G" "" "likely benign" "" "0000650999" "1" "50" "22" "42524178" "42524180" "del" "0" "03575" "CYP2D6_000014" "g.42524178_42524180del" "15/2795 individuals" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "" "" "15 heterozygous, no homozygous; {DB:CLININrs5030656}" "Germline" "" "rs5030656" "0" "" "" "g.42128176_42128178del" "" "VUS" "" "0000651000" "1" "30" "22" "42526670" "42526670" "subst" "4.97121E-5" "03575" "CYP2D6_000021" "g.42526670C>T" "5/2795 individuals" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "" "" "5 heterozygous, no homozygous; {DB:CLININrs5030862}" "Germline" "" "rs5030862" "0" "" "" "g.42130668C>T" "" "likely benign" "" "0000669725" "3" "30" "22" "42523858" "42523858" "subst" "0.00133446" "03575" "CYP2D6_000018" "g.42523858T>G" "2/2793 individuals" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "" "" "2 homozygous; {DB:CLININrs5030867}" "Germline" "" "rs5030867" "0" "" "" "g.42127856T>G" "" "likely benign" "" "0000728196" "0" "50" "22" "42525086" "42525086" "del" "0.00791688" "02329" "CYP2D6_000017" "g.42525086del" "" "" "" "CYP2D6(NM_000106.6):c.454delT (p.W152Gfs*2)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "" "" "VUS" "" "0000984276" "0" "50" "22" "42523514" "42523514" "subst" "0" "01804" "CYP2D6_000282" "g.42523514C>T" "" "" "" "CYP2D6(NM_000106.6):c.1108G>A (p.(Val370Ile))" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "" "" "VUS" "" ## Variants_On_Transcripts ## Do not remove or alter this header ## ## Please note that not necessarily all variants found in the given individuals are shown. This output is restricted to variants in the selected gene. ## Note: Only showing Variants_On_Transcript columns active for Genes CYP2D6 ## Count = 2633 "{{id}}" "{{transcriptid}}" "{{effectid}}" "{{position_c_start}}" "{{position_c_start_intron}}" "{{position_c_end}}" "{{position_c_end_intron}}" "{{VariantOnTranscript/DNA}}" "{{VariantOnTranscript/RNA}}" "{{VariantOnTranscript/Protein}}" "{{VariantOnTranscript/Exon}}" "{{VariantOnTranscript/Haplotype}}" "0000060613" "00023855" "90" "506" "-1" "506" "-1" "c.506-1G>A" "r.506del" "p.Gly169Aspfs*14" "3i" "CYP2D6*4" "0000060614" "00023855" "30" "271" "0" "271" "0" "c.271C>A" "r.271c>a" "p.Leu91Met" "2" "" "0000060615" "00023855" "30" "281" "0" "281" "0" "c.281A>G" "r.281a>g" "p.His94Arg" "2" "" "0000060616" "00023855" "10" "294" "0" "294" "0" "c.294C>G" "r.294c>g" "p.Thr98=" "2" "" "0000060618" "00023855" "90" "-7283" "0" "2152" "0" "c.-7283_*658del" "r.0?" "p.0?" "_1_9_" "CYP2D6*5" "0000060619" "00023855" "90" "-7283" "0" "2152" "0" "c.-7283_*658del" "r.0?" "p.0?" "_1_9_" "CYP2D6*5" "0000060620" "00023855" "90" "-1" "0" "1495" "0" "c.(?_-1)_(*1_?)del" "r.0" "p.0" "_1_9_" "CYP2D6*5" "0000060621" "00023855" "30" "100" "0" "100" "0" "c.100C>T" "r.100c>u" "p.Pro34Ser" "1" "" "0000060622" "00023855" "10" "408" "0" "408" "0" "c.408G>C" "r.408g>c" "p.Val136=" "3" "" "0000060623" "00023855" "30" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "" "0000060624" "00023855" "90" "506" "-1" "506" "-1" "c.506-1G>A" "r.spl" "p.?" "3i" "CYP2D6*4" "0000060625" "00023855" "90" "-1" "0" "1495" "0" "c.(?_-1)_(*1_?)del" "r.0" "p.0" "_1_9_" "CYP2D6*5" "0000060626" "00023855" "50" "100" "0" "100" "0" "c.100C>T" "r.(?)" "p.(Pro34Ser)" "1" "" "0000060627" "00023855" "50" "271" "0" "271" "0" "c.271C>A" "r.(?)" "p.(Leu91Met)" "2" "" "0000060628" "00023855" "50" "281" "0" "281" "0" "c.281A>G" "r.(?)" "p.(His94Arg)" "2" "" "0000060629" "00023855" "50" "1457" "0" "1457" "0" "c.1457G>C" "r.(?)" "p.(Ser486Thr)" "9" "" "0000060630" "00023855" "30" "294" "0" "294" "0" "c.294C>G" "r.(?)" "p.(=)" "2" "" "0000060631" "00023855" "30" "408" "0" "408" "0" "c.408G>C" "r.(?)" "p.(=)" "3" "" "0000060632" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*2D" "0000060633" "00023855" "11" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*2D" "0000060634" "00023855" "99" "841" "0" "843" "0" "c.841_843del" "r.841_843del" "p.Lys281del" "5" "CYP2D6*9" "0000060635" "00023855" "99" "100" "0" "100" "0" "c.100C>T" "r.100c>u" "p.Pro34Ser" "1" "CYP2D6*10A" "0000060636" "00023855" "11" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*10A" "0000060637" "00023855" "11" "408" "0" "408" "0" "c.408G>C" "r.408g>c" "p.Val136=" "3" "CYP2D6*10A" "0000060638" "00023855" "99" "775" "0" "775" "0" "c.775del" "r.775del" "p.Arg259Glyfs*2" "5" "CYP2D6*3" "0000060639" "00023855" "99" "454" "0" "454" "0" "c.454del" "r.454del" "p.Trp152Glyfs*2" "3" "CYP2D6*6A (6)" "0000060640" "00023855" "99" "971" "0" "971" "0" "c.971A>C" "r.971a>c" "p.His324Pro" "6" "CYP2D6*7" "0000060641" "00023855" "99" "505" "0" "505" "0" "c.505G>T" "r.spl?" "p.(Glu169*)" "3" "CYP2D6*8" "0000060642" "00023855" "11" "408" "0" "408" "0" "c.408G>C" "r.408g>c" "p.Val136=" "3" "CYP2D6*8" "0000060643" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*8" "0000060644" "00023855" "11" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*8" "0000060645" "00023855" "99" "181" "-1" "181" "-1" "c.181-1G>C" "r.spl" "p.?" "1i" "CYP2D6*11" "0000060646" "00023855" "11" "408" "0" "408" "0" "c.408G>C" "r.408g>c" "p.Val136=" "3" "CYP2D6*11" "0000060647" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*11" "0000060648" "00023855" "11" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*11" "0000060649" "00023855" "99" "124" "0" "124" "0" "c.124G>A" "r.124g>a" "p.Gly42Arg" "1" "CYP2D6*12" "0000060650" "00023855" "11" "408" "0" "408" "0" "c.408G>C" "r.408g>c" "p.Val136=" "3" "CYP2D6*12" "0000060651" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*12" "0000060652" "00023855" "11" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*12" "0000060653" "00023855" "99" "320" "0" "320" "0" "c.320C>T" "r.spl?" "p.Thr107Ile" "2" "CYP2D6*17" "0000060654" "00023855" "11" "408" "0" "408" "0" "c.408G>C" "r.408g>c" "p.Val136=" "3" "CYP2D6*17" "0000060655" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*17" "0000060656" "00023855" "11" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*17" "0000060657" "00023855" "99" "406" "0" "406" "0" "c.406G>A" "r.(?)" "p.(Val136Ile)" "3" "CYP2D6*29" "0000060658" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*29" "0000060659" "00023855" "50" "1012" "0" "1012" "0" "c.1012G>A" "r.1012g>a" "p.Val338Met" "7" "CYP2D6*29" "0000060660" "00023855" "30" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*29" "0000061081" "00023855" "10" "408" "0" "408" "0" "c.408G>C" "r.408g>c" "p.Val136=" "3" "CYP2D6*41" "0000061082" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*41" "0000061083" "00023855" "99" "985" "39" "985" "39" "c.985+39G>A" "r.[844_985del,=]" "p.[Lys283Valfs*9,=]" "6i" "CYP2D6*41" "0000061084" "00023855" "30" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*41" "0000061085" "00023855" "11" "-1235" "0" "-1235" "0" "c.-1235A>G" "r.=" "p.=" "_1" "CYP2D6*41" "0000061086" "00023855" "11" "-740" "0" "-740" "0" "c.-740C>T" "r.=" "p.=" "_1" "CYP2D6*41" "0000061087" "00023855" "11" "-678" "0" "-678" "0" "c.-678G>A" "r.=" "p.=" "_1" "CYP2D6*41" "0000061091" "00023855" "77" "463" "0" "463" "0" "c.463G>A" "r.463g>a" "p.Glu155Lys" "3" "CYP2D6*45" "0000061092" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*46" "0000061093" "00023855" "30" "1457" "0" "1457" "0" "c.1457G>C" "r.1457g>c" "p.Ser486Thr" "9" "CYP2D6*46" "0000061094" "00023855" "77" "463" "0" "463" "0" "c.463G>A" "r.463g>a" "p.Glu155Lys" "3" "CYP2D6*46" "0000061095" "00023855" "33" "77" "0" "77" "0" "c.77G>A" "r.77g>a" "p.Arg26His" "1" "CYP2D6*46" "0000062769" "00023855" "10" "1174" "-9" "1174" "-9" "c.1174-9C>T" "r.(=)" "p.(=)" "" "" "0000062770" "00023855" "10" "1064" "0" "1064" "0" "c.1064A>G" "r.(?)" "p.(Tyr355Cys)" "" "" "0000062771" "00023855" "90" "841" "0" "843" "0" "c.841_843del" "r.(?)" "p.(Lys281del)" "" "" "0000062772" "00023855" "90" "100" "0" "100" "0" "c.100C>T" "r.(?)" "p.(Pro34Ser)" "" "" "0000062773" "00023855" "59" "985" "39" "985" "39" "c.985+39G>A" "r.spl" "p.?" "6i" "" "0000062774" "00023855" "90" "506" "-1" "506" "-1" "c.506-1G>A" "r.spl?" "p.(=)" "" "" "0000062775" "00023855" "10" "1055" "0" "1055" "0" "c.1055A>G" "r.(?)" "p.(His352Arg)" "" "" "0000062776" "00023855" "10" "1401" "0" "1401" "0" "c.1401G>C" "r.(=)" "p.(=)" "" "" "0000073966" "00023855" "11" "1203" "0" "1203" "0" "c.1203G>A" "r.1203g>a" "p.Ser401=" "8" "CYP2D6*1B" "0000073967" "00023855" "11" "637" "0" "637" "0" "c.637C>T" "r.637c>u" "p.Leu213=" "4" "CYP2D6*1C" "0000073968" "00023855" "11" "801" "0" "801" "0" "c.801C>A" "r.801c>a" "p.Pro267=" "5" "CYP2D6*1D" "0000073970" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*2A" "0000073971" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*2B" "0000073972" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*2C" "0000073973" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*2E" "0000073974" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" "6" "CYP2D6*2F" "0000073975" "00023855" "11" "886" "0" "886" "0" "c.886C>T" "r.886c>u" "p.Arg296Cys" 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