### LOVD-version 3000-30b ### Full data download ### To import, do not remove or alter this header ### ## Filter: (gene_public = FSHR) # charset = UTF-8 ## Genes ## Do not remove or alter this header ## ## Count = 1 "{{id}}" "{{name}}" "{{chromosome}}" "{{chrom_band}}" "{{imprinting}}" "{{refseq_genomic}}" "{{refseq_UD}}" "{{reference}}" "{{url_homepage}}" "{{url_external}}" "{{allow_download}}" "{{id_hgnc}}" "{{id_entrez}}" "{{id_omim}}" "{{show_hgmd}}" "{{show_genecards}}" "{{show_genetests}}" "{{show_orphanet}}" "{{note_index}}" "{{note_listing}}" "{{refseq}}" "{{refseq_url}}" "{{disclaimer}}" "{{disclaimer_text}}" "{{header}}" "{{header_align}}" "{{footer}}" "{{footer_align}}" "{{created_by}}" "{{created_date}}" "{{edited_by}}" "{{edited_date}}" "{{updated_by}}" "{{updated_date}}" "FSHR" "follicle stimulating hormone receptor" "2" "p21-p16" "unknown" "NG_008146.1" "UD_132084546098" "" "https://www.LOVD.nl/FSHR" "Finnish Disease Database \r\nOMIM#233300 ODG1 " "1" "3969" "2492" "136435" "1" "1" "1" "1" "The establishment of this gene variant database (LSDB) was supported by the European Community\'s Seventh Framework Programme (FP7/2007-2013) under grant agreement nº 200754 - the GEN2PHEN project.\r\nThe database was initially part of the Finnish Disease Resource (FinDis; Polvi et al: Hum Mutat. 2013:34:1458-66). We gratefully acknowledge the support of Juha Muilu acting as curator until 2015." "" "g" "https://databases.lovd.nl/shared/refseq/FSHR_codingDNA.html" "1" "" "" "-1" "" "-1" "00001" "2012-08-23 00:00:00" "00006" "2023-02-08 10:22:35" "00000" "2025-05-05 21:14:00" ## Transcripts ## Do not remove or alter this header ## ## Count = 1 "{{id}}" "{{geneid}}" "{{name}}" "{{id_mutalyzer}}" "{{id_ncbi}}" "{{id_ensembl}}" "{{id_protein_ncbi}}" "{{id_protein_ensembl}}" "{{id_protein_uniprot}}" "{{remarks}}" "{{position_c_mrna_start}}" "{{position_c_mrna_end}}" "{{position_c_cds_end}}" "{{position_g_mrna_start}}" "{{position_g_mrna_end}}" "{{created_by}}" "{{created_date}}" "{{edited_by}}" "{{edited_date}}" "00000269" "FSHR" "transcript variant 1" "002" "NM_000145.3" "" "NP_000136.2" "" "" "" "-110" "2664" "2088" "49381666" "49189296" "00015" "2012-08-23 13:45:24" "" "" ## Diseases ## Do not remove or alter this header ## ## Count = 6 "{{id}}" "{{symbol}}" "{{name}}" "{{inheritance}}" "{{id_omim}}" "{{tissues}}" "{{features}}" "{{remarks}}" "{{created_by}}" "{{created_date}}" "{{edited_by}}" "{{edited_date}}" "00030" "ODG1" "dysgenesis, ovarian, type 1" "AR" "233300" "" "" "" "00001" "2012-08-27 15:15:31" "00006" "2023-02-08 10:19:37" "00198" "?" "unclassified / mixed" "" "" "" "" "" "00006" "2013-09-13 14:21:47" "00006" "2024-11-23 09:38:12" "02110" "twinning" "twinning, dizygotic" "AR" "276400" "" "" "" "00006" "2014-09-25 23:29:40" "00006" "2023-02-08 10:21:05" "02737" "OHSS" "ovarian hyperstimulation syndrome" "AD" "608115" "" "" "" "00006" "2014-09-25 23:29:40" "00006" "2023-02-08 10:20:02" "04187" "POF" "ovarian failure, premature (POF)" "" "" "" "" "" "00006" "2015-02-14 15:50:12" "00006" "2015-12-08 23:53:05" "05370" "INFF" "infertility, female (INFF)" "" "" "" "" "" "00006" "2017-12-29 16:08:25" "" "" ## Genes_To_Diseases ## Do not remove or alter this header ## ## Count = 3 "{{geneid}}" "{{diseaseid}}" "FSHR" "00030" "FSHR" "02110" "FSHR" "02737" ## Individuals ## Do not remove or alter this header ## ## Count = 26 "{{id}}" "{{fatherid}}" "{{motherid}}" "{{panelid}}" "{{panel_size}}" "{{license}}" "{{owned_by}}" "{{Individual/Reference}}" "{{Individual/Remarks}}" "{{Individual/Gender}}" "{{Individual/Consanguinity}}" "{{Individual/Origin/Geographic}}" "{{Individual/Age_of_death}}" "{{Individual/VIP}}" "{{Individual/Data_av}}" "{{Individual/Treatment}}" "{{Individual/Origin/Population}}" "{{Individual/Individual_ID}}" "00292791" "" "" "" "1" "" "03575" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "analysis 2794 individuals (India)" "" "" "India" "" "0" "" "" "" "" "00431305" "" "" "" "1" "" "00006" "{PMID:Chen 2023:36704038}" "2-generation family, 1 affected, unaffected heterozygous carrier parents" "F" "no" "China" "" "0" "" "" "" "patient" "00431306" "" "" "" "1" "" "00006" "{PMID:Touraine 1999:10551778}" "2-generation family, 1 affected, unaffected heterozygous carrier parents" "F" "no" "France" "" "0" "" "" "" "patient" "00431307" "" "" "" "1" "" "00006" "{PMID:Kuechler 2010:20087398}" "2-generation family, 1 affected, unaffected heterozygous carrier parents" "F" "" "Germany" "" "0" "" "" "" "patient" "00431308" "" "" "" "1" "" "00006" "{PMID:Achrekar 2010:20237833}" "" "F" "" "India" "" "0" "" "" "" "patient" "00431309" "" "" "" "1" "" "00006" "{PMID:Beau 1998:9769327}" "" "F" "no" "Armenia" "" "0" "" "" "" "patient" "00431310" "" "" "" "1" "" "00006" "{PMID:Meduri 2003:12915623}" "adopted" "F" "" "Germany" "" "0" "" "" "white" "patient" "00431311" "" "" "" "1" "" "00006" "{PMID: Doherty 2002:11889179}" "" "F" "no" "Australia" "" "0" "" "" "Finland" "patient" "00431312" "" "" "" "1" "" "00006" "{PMID:Allen 2003:12571157}" "" "F" "no" "United Kingdom (Great Britain)" "" "0" "" "" "" "patient" "00431313" "" "" "" "1" "" "00006" "{PMID:Nakamura 2008:19172541}" "" "F" "" "Japan" "" "0" "" "" "" "patient" "00431314" "" "" "" "2" "" "00006" "{PMID:Aittomaki 1995:7553856}" "2-generation family, 2 affected sisters, unaffected heterozygous carrier parents/relatives" "" "yes" "Finland" "" "0" "" "" "" "Fam1Pat17" "00431315" "" "" "00431314" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "yes" "Finland" "" "0" "" "" "" "Fam1Pat18" "00431316" "" "" "" "2" "" "00006" "{PMID:Aittomaki 1995:7553856}" "2-generation family, 2 affected sisters, unaffected heterozygous carrier parents/relatives" "" "yes" "Finland" "" "0" "" "" "" "Fam2Pat29" "00431317" "" "" "00431316" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "yes" "Finland" "" "0" "" "" "" "Fam2Pat210" "00431318" "" "" "" "3" "" "00006" "{PMID:Aittomaki 1995:7553856}" "2-generation family, 3 affected sisters, unaffected heterozygous carrier parents/relatives" "" "" "Finland" "" "0" "" "" "" "Fam4PatII1" "00431319" "" "" "00431318" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "" "Finland" "" "0" "" "" "" "Fam4PatII2" "00431320" "" "" "00431318" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "" "Finland" "" "0" "" "" "" "Fam4PatII6" "00431321" "" "" "" "2" "" "00006" "{PMID:Aittomaki 1995:7553856}" "2-generation family, 2 affected sisters, unaffected heterozygous carrier parents/relatives" "" "" "Finland" "" "0" "" "" "" "Fam5PatII2" "00431322" "" "" "00431321" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "" "Finland" "" "0" "" "" "" "Fam5PatII3" "00431323" "" "" "" "4" "" "00006" "{PMID:Aittomaki 1995:7553856}" "2-generation family, 4 affected sisters, unaffected heterozygous carrier parents/relatives" "" "" "Finland" "" "0" "" "" "" "Fam6Pat65" "00431324" "" "" "00431323" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "" "Finland" "" "0" "" "" "" "Fam6Pat67" "00431325" "" "" "00431323" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "" "Finland" "" "0" "" "" "" "Fam6Pat68" "00431326" "" "" "00431323" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "" "Finland" "" "0" "" "" "" "Fam6Pat610" "00431327" "" "" "" "2" "" "00006" "{PMID:Aittomaki 1995:7553856}" "2-generation family, 2 affected sisters, unaffected heterozygous carrier parents/relatives" "" "" "Finland" "" "0" "" "" "" "Fam7PatII2" "00431328" "" "" "00431327" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "sister" "" "" "Finland" "" "0" "" "" "" "Fam7PatII3" "00431329" "" "" "" "1" "" "00006" "{PMID:Aittomaki 1995:7553856}" "" "F" "" "Finland" "" "0" "" "" "" "family" ## Individuals_To_Diseases ## Do not remove or alter this header ## ## Count = 26 "{{individualid}}" "{{diseaseid}}" "00292791" "00198" "00431305" "05370" "00431306" "04187" "00431307" "00198" "00431308" "00198" "00431309" "00198" "00431310" "05370" "00431311" "04187" "00431312" "00198" "00431313" "05370" "00431314" "00030" "00431315" "00030" "00431316" "00030" "00431317" "00030" "00431318" "00030" "00431319" "00030" "00431320" "00030" "00431321" "00030" "00431322" "00030" "00431323" "00030" "00431324" "00030" "00431325" "00030" "00431326" "00030" "00431327" "00030" "00431328" "00030" "00431329" "00030" ## Phenotypes ## Do not remove or alter this header ## ## Note: Only showing Phenotype columns active for Diseases 00030, 00198, 02110, 02737, 04187, 05370 ## Count = 24 "{{id}}" "{{diseaseid}}" "{{individualid}}" "{{owned_by}}" "{{Phenotype/Inheritance}}" "{{Phenotype/Age}}" "{{Phenotype/Additional}}" "{{Phenotype/Age/Onset}}" "{{Phenotype/Age/Diagnosis}}" "{{Phenotype/Onset}}" "{{Phenotype/Protein}}" "{{Phenotype/Tumor/MSI}}" "{{Phenotype/Enzyme/CPK}}" "{{Phenotype/Heart/Myocardium}}" "{{Phenotype/Lung}}" "{{Phenotype/Diagnosis/Definite}}" "{{Phenotype/Diagnosis/Initial}}" "{{Phenotype/Diagnosis/Criteria}}" "0000321905" "05370" "00431305" "00006" "Familial, autosomal recessive" "29y" "see paper; ..., primary ovarian insufficiency, resistant ovary syndrome; 15y-menarche, irregular menstrual cycles (15-180d)" "" "" "" "" "" "" "" "" "" "infertility" "" "0000321906" "04187" "00431306" "00006" "Familial, autosomal recessive" "19y" "see paper; ..., primary amenorrhea, 13y-puberty, normal development secondary sex characteristics" "" "" "" "" "" "" "" "" "" "premature ovarian failure" "" "0000321907" "00198" "00431307" "00006" "Familial, autosomal recessive" "17y" "see paper; ..., primary amenorrhea, hypergonadotropic hypogonadism, disturbed folliculogenesis" "" "" "" "" "" "" "" "" "" "" "" "0000321908" "00198" "00431308" "00006" "Familial, autosomal recessive" "16y" "see paper; ..., primary amenorrhea; ultrasonography hypoplastic uterus, thin endometrium" "" "" "" "" "" "" "" "" "" "primary amenorrhea" "" "0000321909" "00198" "00431309" "00006" "Familial, autosomal recessive" "30y" "see paper; ..., secondary amenorrhea, very high plasma gonadotropin concentrations (especially FSH); ultrasonography normal sized ovaries, antral follicles up to 5 mm; normal follicular development, small antral stage, disruption at further stages" "" "" "" "" "" "" "" "" "" "secondary amenorrhea" "" "0000321910" "05370" "00431310" "00006" "Familial, autosomal recessive" "26y" "see paper; ..., infertility, delayed puberty, primary amenorrhea" "" "" "" "" "" "" "" "" "ODG1" "infertility" "" "0000321911" "04187" "00431311" "00006" "Familial, autosomal recessive" "17y" "see paper; ..., primary amenorrhea, normal female secondary sexual characteristics, heigh 163 cm, weight 51 kg; high serum gonadotropin concentrations" "" "" "" "" "" "" "" "" "ODG1" "primary amenorrhea" "" "0000321912" "00198" "00431312" "00006" "Familial, autosomal recessive" "17y" "see paper; ..., hypergonadotrophic hypogonadism, delayed puberty, primary amenorrhoea; 13y-pubic hair development, 14y-breast development" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotrophic hypogonadism" "" "0000321913" "05370" "00431313" "00006" "Familial, autosomal recessive" "25y" "see paper; ..., primary amenorrhea, moderately developed secondary sex characteristics, normal sized ovaries, small antral follicles" "" "" "" "" "" "" "" "" "ODG1" "infertility" "" "0000321914" "00030" "00431314" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321915" "00030" "00431315" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321916" "00030" "00431316" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321917" "00030" "00431317" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321918" "00030" "00431318" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321919" "00030" "00431319" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321920" "00030" "00431320" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321921" "00030" "00431321" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321922" "00030" "00431322" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321923" "00030" "00431323" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321924" "00030" "00431324" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321925" "00030" "00431325" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321926" "00030" "00431326" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321927" "00030" "00431327" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" "0000321928" "00030" "00431328" "00006" "Familial, autosomal recessive" "" "" "" "" "" "" "" "" "" "" "ODG1" "hypergonadotropic ovarian dysgenesis" "" ## Screenings ## Do not remove or alter this header ## ## Count = 26 "{{id}}" "{{individualid}}" "{{variants_found}}" "{{owned_by}}" "{{created_by}}" "{{created_date}}" "{{edited_by}}" "{{edited_date}}" "{{Screening/Technique}}" "{{Screening/Template}}" "{{Screening/Tissue}}" "{{Screening/Remarks}}" "0000293959" "00292791" "1" "03575" "00006" "2020-03-11 19:30:02" "" "" "arraySNP" "DNA" "" "Infinium Global Screening Array v1.0" "0000432717" "00431305" "1" "00006" "00006" "2023-02-08 10:32:42" "" "" "SEQ;SEQ-NG" "DNA" "" "WES" "0000432718" "00431306" "1" "00006" "00006" "2023-02-08 10:59:09" "" "" "SEQ" "DNA" "" "" "0000432719" "00431307" "1" "00006" "00006" "2023-02-08 11:10:03" "" "" "FISH;microscope;SEQ" "DNA" "" "" "0000432720" "00431308" "1" "00006" "00006" "2023-02-08 12:13:07" "" "" "SEQ" "DNA" "" "" "0000432721" "00431309" "1" "00006" "00006" "2023-02-08 12:20:29" "" "" "SEQ" "DNA" "" "" "0000432722" "00431310" "1" "00006" "00006" "2023-02-08 12:30:05" "" "" "SEQ" "DNA" "" "" "0000432723" "00431311" "1" "00006" "00006" "2023-02-08 13:02:36" "" "" "SEQ" "DNA" "" "" "0000432724" "00431312" "1" "00006" "00006" "2023-02-08 13:12:29" "" "" "SEQ" "DNA" "" "" "0000432725" "00431313" "1" "00006" "00006" "2023-02-08 13:19:40" "" "" "SEQ" "DNA" "" "" "0000432726" "00431314" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000432727" "00431315" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "RT-PCR;SEQ" "DNA;RNA" "" "" "0000432728" "00431316" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432729" "00431317" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432730" "00431318" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432731" "00431319" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432732" "00431320" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432733" "00431321" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432734" "00431322" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432735" "00431323" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432736" "00431324" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432737" "00431325" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432738" "00431326" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432739" "00431327" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432740" "00431328" "1" "00006" "00006" "2023-02-08 14:00:00" "" "" "SEQ" "DNA" "" "" "0000432741" "00431329" "1" "00006" "00006" "2023-02-08 14:01:17" "" "" "DGGE;SEQ" "DNA" "" "" ## Screenings_To_Genes ## Do not remove or alter this header ## ## Count = 24 "{{screeningid}}" "{{geneid}}" "0000432718" "FSHR" "0000432719" "FSHR" "0000432720" "FSHR" "0000432721" "FSHR" "0000432722" "FSHR" "0000432723" "FSHR" "0000432724" "FSHR" "0000432725" "FSHR" "0000432726" "FSHR" "0000432727" "FSHR" "0000432728" "FSHR" "0000432729" "FSHR" "0000432730" "FSHR" "0000432731" "FSHR" "0000432732" "FSHR" "0000432733" "FSHR" "0000432734" "FSHR" "0000432735" "FSHR" "0000432736" "FSHR" "0000432737" "FSHR" "0000432738" "FSHR" "0000432739" "FSHR" "0000432740" "FSHR" "0000432741" "FSHR" ## Variants_On_Genome ## Do not remove or alter this header ## ## Please note that not necessarily all variants found in the given individuals are shown. This output is restricted to variants in the selected gene. ## Count = 51 "{{id}}" "{{allele}}" "{{effectid}}" "{{chromosome}}" "{{position_g_start}}" "{{position_g_end}}" "{{type}}" "{{average_frequency}}" "{{owned_by}}" "{{VariantOnGenome/DBID}}" "{{VariantOnGenome/DNA}}" "{{VariantOnGenome/Frequency}}" "{{VariantOnGenome/Reference}}" "{{VariantOnGenome/Restriction_site}}" "{{VariantOnGenome/Published_as}}" "{{VariantOnGenome/Remarks}}" "{{VariantOnGenome/Genetic_origin}}" "{{VariantOnGenome/Segregation}}" "{{VariantOnGenome/dbSNP}}" "{{VariantOnGenome/VIP}}" "{{VariantOnGenome/Methylation}}" "{{VariantOnGenome/ISCN}}" "{{VariantOnGenome/DNA/hg38}}" "{{VariantOnGenome/ClinVar}}" "{{VariantOnGenome/ClinicalClassification}}" "{{VariantOnGenome/ClinicalClassification/Method}}" "0000001470" "21" "99" "2" "49216161" "49216161" "subst" "4.06474E-5" "00015" "FSHR_000001" "g.49216161A>G" "" "{PMID:Beau 1998:9769327}, {OMIM136435:0003}" "" "" "in vitro functional analysis shows impaired cell surface expression of FSHR" "Germline" "yes" "rs121909659" "0" "" "" "g.48989022A>G" "" "pathogenic (recessive)" "" "0000001471" "3" "99" "2" "49210264" "49210264" "subst" "0.000763818" "00015" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}, {OMIM136435:0001}" "" "" "in vitro functional analysis shows dramatic reduction of binding capacity and signal transduction of the variant receptor" "SUMMARY record" "" "rs121909658" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000001472" "0" "77" "2" "49210057" "49210057" "subst" "0" "00015" "FSHR_000003" "g.49210057A>C" "" "{PMID:Nakamura 2008:19172541}" "" "" "" "Germline" "" "" "0" "" "" "g.48982918A>C" "" "likely pathogenic (recessive)" "" "0000001473" "11" "99" "2" "49196020" "49196020" "subst" "0" "00015" "FSHR_000004" "g.49196020T>A" "" "{PMID:Touraine 1999:10551778}" "" "" "in vitro functional analysis shows impaired targeting FSHR to cell membrane" "Germline" "" "" "0" "" "" "g.48968881T>A" "" "pathogenic (recessive)" "" "0000001474" "11" "99" "2" "49190917" "49190917" "subst" "4.06521E-6" "00015" "FSHR_000005" "g.49190917G>C" "" "{PMID:Allen 2003:12571157}" "" "" "in vitro functional analysis shows completely inactivity and no FSH binding; unknown variant 2 nd chromosome" "Germline" "" "" "0" "" "" "g.48963778G>C" "" "pathogenic (recessive)" "" "0000001475" "1" "99" "2" "49190705" "49190705" "subst" "4.07266E-6" "00015" "FSHR_000006" "g.49190705C>T" "" "{PMID: Doherty 2002:11889179}, {OMIM136435:0007}" "" "" "in vitro functional analysis shows almost totally abolished cAMP second messenger response" "Germline" "" "rs121909661" "0" "" "" "g.48963566C>T" "" "pathogenic (recessive)" "" "0000001476" "3" "99" "2" "49190405" "49190405" "subst" "0" "00015" "FSHR_000007" "g.49190405G>T" "" "{PMID:Meduri 2003:12915623}, {OMIM136435:0010}" "" "" "in vitro functional analysis shows impaired adenylate cyclase stimulation" "Germline" "" "rs121909662" "0" "" "" "g.48963266G>T" "" "pathogenic (recessive)" "" "0000001477" "11" "99" "2" "49190243" "49190243" "subst" "1.2217E-5" "00015" "FSHR_000008" "g.49190243G>A" "" "{PMID:Beau 1998:9769327}, {OMIM136435:0004}" "" "" "in vitro functional analysis COS-7 cells shows altered signal transduction receptor" "Germline" "yes" "rs121909660" "0" "" "" "g.48963104G>A" "" "pathogenic (recessive)" "" "0000001478" "3" "77" "2" "49190236" "49190236" "subst" "0" "00015" "FSHR_000009" "g.49190236G>A" "" "{PMID:Achrekar 2010:20237833}" "" "1723C>T" "" "Germline" "" "" "0" "" "" "g.48963097G>A" "" "likely pathogenic" "" "0000001479" "21" "99" "2" "49190159" "49190159" "subst" "0" "00015" "FSHR_000010" "g.49190159G>C" "" "{PMID:Touraine 1999:10551778}" "" "" "in vitro analysis shows impairment in signal transduction" "Germline" "" "" "0" "" "" "g.48963020G>C" "" "pathogenic (recessive)" "" "0000001481" "11" "99" "2" "49190200" "49190200" "subst" "0" "00015" "FSHR_000011" "g.49190200G>T" "" "{PMID:Kuechler 2010:20087398}, {OMIM136435:0014}" "" "" "in vitro functional analysis shows complete lack of signal transduction" "Germline" "" "" "0" "" "" "g.48963061G>T" "" "pathogenic (recessive)" "" "0000001483" "21" "99" "2" "49042399" "49205110" "del" "0" "00015" "FSHR_000012" "g.49042399_49205110del" "" "{PMID:Kuechler 2010:20087398}" "" "del (rs6729545_rs9636432)_(rs2268359_rs13396575)del" "deletion 162.7 kb (30 SNPs); variant inherited from unaffected mother" "Germline" "" "" "0" "" "46,XX,t(2;8)(p16.3or21;p23.1)" "g.48815260_48977971del" "" "pathogenic" "" "0000249752" "0" "50" "2" "49190548" "49190548" "subst" "4.08277E-6" "02325" "FSHR_000014" "g.49190548A>C" "" "" "" "FSHR(NM_000145.4):c.1412T>G (p.I471S)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "0" "" "" "g.48963409A>C" "" "VUS" "" "0000280926" "0" "10" "2" "49189921" "49189921" "subst" "0.573817" "02325" "FSHR_000013" "g.49189921C>T" "" "" "" "FSHR(NM_000145.4):c.2039G>A (p.S680N)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "0" "" "" "g.48962782C>T" "" "benign" "" "0000280927" "0" "10" "2" "49191041" "49191041" "subst" "0.553131" "02325" "FSHR_000015" "g.49191041C>T" "" "" "" "FSHR(NM_000145.4):c.919G>A (p.A307T)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "0" "" "" "g.48963902C>T" "" "benign" "" "0000287965" "0" "30" "2" "49216155" "49216155" "subst" "0.00403186" "01943" "FSHR_000017" "g.49216155C>T" "" "" "" "FSHR(NM_000145.3):c.485G>A (p.R162K)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "0" "" "" "g.48989016C>T" "" "likely benign" "" "0000287966" "0" "30" "2" "49216145" "49216145" "subst" "4.06392E-5" "01943" "FSHR_000016" "g.49216145G>A" "" "" "" "FSHR(NM_000145.3):c.495C>T (p.F165=)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "0" "" "" "g.48989006G>A" "" "likely benign" "" "0000516412" "0" "70" "2" "49190162" "49190162" "subst" "0" "02329" "FSHR_000018" "g.49190162G>T" "" "" "" "FSHR(NM_000145.4):c.1798C>A (p.P600T)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "g.48963023G>T" "" "likely pathogenic" "" "0000516413" "0" "50" "2" "49190377" "49190377" "subst" "8.14591E-6" "01943" "FSHR_000019" "g.49190377T>C" "" "" "" "FSHR(NM_000145.3):c.1583A>G (p.Q528R)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "g.48963238T>C" "" "VUS" "" "0000516414" "0" "70" "2" "49195844" "49195844" "subst" "6.10416E-5" "02329" "FSHR_000020" "g.49195844G>A" "" "" "" "FSHR(NM_000145.4):c.847C>T (p.R283W)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "g.48968705G>A" "" "likely pathogenic" "" "0000516415" "0" "10" "2" "49210116" "49210116" "subst" "0.00414284" "01943" "FSHR_000021" "g.49210116G>A" "" "" "" "FSHR(NM_000145.3):c.603C>T (p.S201=)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "g.48982977G>A" "" "benign" "" "0000650648" "1" "90" "2" "49190326" "49190326" "subst" "4.0709E-6" "03575" "FSHR_000022" "g.49190326A>G" "1/2795 individuals" "{PMID:Narang 2020:32906206}, {DOI:Narang 2020:10.1002/humu.24102}" "" "" "1 heterozygous, no homozygous; {DB:CLININrs121909664}" "Germline" "" "rs121909664" "0" "" "" "g.48963187A>G" "" "pathogenic" "" "0000800740" "0" "50" "2" "49190291" "49190291" "subst" "7.32989E-5" "02325" "FSHR_000023" "g.49190291G>A" "" "" "" "FSHR(NM_000145.4):c.1669C>T (p.R557W)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "" "" "VUS" "" "0000800741" "0" "50" "2" "49190645" "49190645" "subst" "4.07388E-6" "02325" "FSHR_000024" "g.49190645C>T" "" "" "" "FSHR(NM_000145.4):c.1315G>A (p.G439R)" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "" "" "VUS" "" "0000829418" "0" "50" "2" "27600408" "62081181" "dup" "0" "00000" "FSHR_000025" "g.27600408_62081181dup" "" "{PMID:Ellingsford 2018:29074561}" "" "chr2:27600408–62081181" "" "Germline" "" "" "0" "" "" "" "" "VUS" "" "0000918294" "11" "90" "2" "49190576" "49190576" "subst" "0" "00006" "FSHR_000026" "g.49190576C>G" "" "{PMID:Chen 2023:36704038}" "" "" "in vitro functional analysis shows barely detectable levels of intracellular signaling in cAMP-dependent CRE-reporter activity and ERK activation and severely reduced plasma membrane receptor expression" "Germline" "" "" "0" "" "" "g.48963437C>G" "" "pathogenic (recessive)" "" "0000918295" "21" "90" "2" "49190098" "49190098" "subst" "0" "00006" "FSHR_000027" "g.49190098G>A" "" "{PMID:Chen 2023:36704038}" "" "" "in vitro functional analysis shows partial loss of receptor activation without disruption cell surface expression" "Germline" "" "" "0" "" "" "g.48962959G>A" "" "pathogenic (recessive)" "" "0000918301" "2" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID: Doherty 2002:11889179}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918302" "0" "50" "2" "49191041" "49191041" "subst" "0.553131" "00006" "FSHR_000015" "g.49191041C>T" "" "{PMID:Nakamura 2008:19172541}" "" "" "" "Germline" "" "" "0" "" "" "g.48963902C>T" "" "VUS" "" "0000918303" "0" "30" "2" "49189921" "49189921" "subst" "0.573817" "00006" "FSHR_000013" "g.49189921C>T" "" "{PMID:Nakamura 2008:19172541}" "" "" "" "Germline" "" "" "0" "" "" "g.48962782C>T" "" "likely benign" "" "0000918304" "3" "30" "2" "49189199" "49189199" "subst" "0" "00006" "FSHR_000028" "g.49189199G>A" "" "{PMID:Allen 2003:12571157}" "" "(c.*673C>T)" "" "Germline" "" "" "0" "" "" "" "" "likely benign" "" "0000918305" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918306" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918307" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918308" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918309" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918310" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918311" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918312" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918313" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918314" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918315" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918316" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918317" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918318" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918319" "3" "90" "2" "49210264" "49210264" "subst" "0.000763818" "00006" "FSHR_000002" "g.49210264G>A" "" "{PMID:Aittomaki 1995:7553856}" "" "" "" "Germline" "" "" "0" "" "" "g.48983125G>A" "" "pathogenic (recessive)" "" "0000918320" "3" "30" "2" "49189921" "49189921" "subst" "0.573817" "00006" "FSHR_000013" "g.49189921C>T" "" "{PMID:Aittomaki 1995:7553856}" "" "G2039A" "" "Germline" "yes" "" "0" "" "" "g.48962782C>T" "" "likely benign" "" "0000923764" "0" "70" "2" "49190560" "49190560" "subst" "8.16347E-6" "02327" "FSHR_000029" "g.49190560C>A" "" "" "" "" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "" "" "likely pathogenic" "" "0000975355" "0" "50" "2" "49247265" "49247265" "subst" "0" "02327" "FSHR_000030" "g.49247265C>T" "" "" "" "" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "" "" "VUS" "" "0000992939" "0" "30" "2" "49244665" "49244665" "subst" "0" "01804" "FSHR_000031" "g.49244665G>A" "" "" "" "FSHR(NM_000145.3):c.337C>T (p.(Pro113Ser))" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "" "" "likely benign" "" "0001033402" "0" "70" "2" "49190692" "49190692" "subst" "0" "01804" "FSHR_000032" "g.49190692A>G" "" "" "" "FSHR(NM_000145.4):c.1268T>C (p.(Ile423Thr))" "VKGL data sharing initiative Nederland" "CLASSIFICATION record" "" "" "" "" "" "" "" "likely pathogenic" "" ## Variants_On_Transcripts ## Do not remove or alter this header ## ## Please note that not necessarily all variants found in the given individuals are shown. This output is restricted to variants in the selected gene. ## Note: Only showing Variants_On_Transcript columns active for Genes FSHR ## Count = 51 "{{id}}" "{{transcriptid}}" "{{effectid}}" "{{position_c_start}}" "{{position_c_start_intron}}" "{{position_c_end}}" "{{position_c_end_intron}}" "{{VariantOnTranscript/DNA}}" "{{VariantOnTranscript/RNA}}" "{{VariantOnTranscript/Protein}}" "{{VariantOnTranscript/Exon}}" "0000001470" "00000269" "99" "479" "0" "479" "0" "c.479T>C" "r.(479u>c)" "p.(Ile160Thr)" "6" "0000001471" "00000269" "99" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000001472" "00000269" "77" "662" "0" "662" "0" "c.662T>G" "r.(662u>g)" "p.(Val221Gly)" "8" "0000001473" "00000269" "99" "671" "0" "671" "0" "c.671A>T" "r.(671a>u)" "p.(Asp224Val)" "9" "0000001474" "00000269" "99" "1043" "0" "1043" "0" "c.1043C>G" "r.(1043c>g)" "p.(Pro348Arg)" "10" "0000001475" "00000269" "99" "1255" "0" "1255" "0" "c.1255G>A" "r.(1255g>a)" "p.(Ala419Thr)" "10" "0000001476" "00000269" "99" "1555" "0" "1555" "0" "c.1555C>A" "r.(1555c>a)" "p.(Pro519Thr)" "10" "0000001477" "00000269" "99" "1717" "0" "1717" "0" "c.1717C>T" "r.(1717c>u)" "p.(Arg573Cys)" "10" "0000001478" "00000269" "77" "1724" "0" "1724" "0" "c.1724C>T" "r.(1724c>u)" "p.(Ala575Val)" "10" "0000001479" "00000269" "99" "1801" "0" "1801" "0" "c.1801C>G" "r.(1801c>g)" "p.(Leu601Val)" "10" "0000001481" "00000269" "99" "1760" "0" "1760" "0" "c.1760C>A" "r.(1760c>a)" "p.(Pro587His)" "10" "0000001483" "00000269" "99" "0" "0" "0" "0" "c.(525-1608_668+4941)_*576{0}" "r.?" "p.?" "_8i_10_" "0000249752" "00000269" "50" "1412" "0" "1412" "0" "c.1412T>G" "r.(?)" "p.(Ile471Ser)" "" "0000280926" "00000269" "10" "2039" "0" "2039" "0" "c.2039G>A" "r.(?)" "p.(Ser680Asn)" "" "0000280927" "00000269" "10" "919" "0" "919" "0" "c.919G>A" "r.(?)" "p.(Ala307Thr)" "" "0000287965" "00000269" "30" "485" "0" "485" "0" "c.485G>A" "r.(?)" "p.(Arg162Lys)" "" "0000287966" "00000269" "30" "495" "0" "495" "0" "c.495C>T" "r.(?)" "p.(Phe165=)" "" "0000516412" "00000269" "70" "1798" "0" "1798" "0" "c.1798C>A" "r.(?)" "p.(Pro600Thr)" "" "0000516413" "00000269" "50" "1583" "0" "1583" "0" "c.1583A>G" "r.(?)" "p.(Gln528Arg)" "" "0000516414" "00000269" "70" "847" "0" "847" "0" "c.847C>T" "r.(?)" "p.(Arg283Trp)" "" "0000516415" "00000269" "10" "603" "0" "603" "0" "c.603C>T" "r.(?)" "p.(Ser201=)" "" "0000650648" "00000269" "90" "1634" "0" "1634" "0" "c.1634T>C" "r.(?)" "p.(Ile545Thr)" "" "0000800740" "00000269" "50" "1669" "0" "1669" "0" "c.1669C>T" "r.(?)" "p.(Arg557Trp)" "" "0000800741" "00000269" "50" "1315" "0" "1315" "0" "c.1315G>A" "r.(?)" "p.(Gly439Arg)" "" "0000829418" "00000269" "50" "-8388608" "0" "8388607" "0" "c.-12699625_*21589464dup" "r.0?" "p.0?" "" "0000918294" "00000269" "90" "1384" "0" "1384" "0" "c.1384G>C" "r.(?)" "p.(Ala462Pro)" "" "0000918295" "00000269" "90" "1862" "0" "1862" "0" "c.1862C>T" "r.(?)" "p.(Ala621Val)" "" "0000918301" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "" "0000918302" "00000269" "50" "919" "0" "919" "0" "c.919G>A" "r.(?)" "p.(Ala307Thr)" "10" "0000918303" "00000269" "30" "2039" "0" "2039" "0" "c.2039G>A" "r.(2039g>a)" "p.(Ser680Asn)" "" "0000918304" "00000269" "30" "0" "0" "0" "0" "-" "r.(=)" "p.(=)" "10_" "0000918305" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.566c>u" "p.Ala189Val" "7" "0000918306" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.566c>u" "p.Ala189Val" "7" "0000918307" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918308" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918309" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918310" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918311" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918312" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918313" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918314" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918315" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918316" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918317" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918318" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918319" "00000269" "90" "566" "0" "566" "0" "c.566C>T" "r.(566c>u)" "p.(Ala189Val)" "7" "0000918320" "00000269" "30" "2039" "0" "2039" "0" "c.2039G>A" "r.(2039g>a)" "p.(Ser680Asn)" "10" "0000923764" "00000269" "70" "1400" "0" "1400" "0" "c.1400G>T" "r.(?)" "p.(Arg467Ile)" "" "0000975355" "00000269" "50" "259" "0" "259" "0" "c.259G>A" "r.(?)" "p.(Glu87Lys)" "" "0000992939" "00000269" "30" "337" "0" "337" "0" "c.337C>T" "r.(?)" "p.(Pro113Ser)" "" "0001033402" "00000269" "70" "1268" "0" "1268" "0" "c.1268T>C" "r.(?)" "p.(Ile423Thr)" "" ## Screenings_To_Variants ## Do not remove or alter this header ## ## Count = 34 "{{screeningid}}" "{{variantid}}" "0000293959" "0000650648" "0000432717" "0000918294" "0000432717" "0000918295" "0000432718" "0000001473" "0000432718" "0000001479" "0000432719" "0000001481" "0000432719" "0000001483" "0000432720" "0000001478" "0000432721" "0000001470" "0000432721" "0000001477" "0000432722" "0000001476" "0000432723" "0000001475" "0000432723" "0000918301" "0000432724" "0000001474" "0000432724" "0000918304" "0000432725" "0000001472" "0000432725" "0000918302" "0000432725" "0000918303" "0000432726" "0000918305" "0000432727" "0000918306" "0000432728" "0000918307" "0000432729" "0000918308" "0000432730" "0000918309" "0000432731" "0000918310" "0000432732" "0000918311" "0000432733" "0000918312" "0000432734" "0000918313" "0000432735" "0000918314" "0000432736" "0000918315" "0000432737" "0000918316" "0000432738" "0000918317" "0000432739" "0000918318" "0000432740" "0000918319" "0000432741" "0000918320"