(intronic numbering for coding DNA Reference Sequence)
. . . . g.16431
gtacccctggcccagccccacccttgccatccttgccatgcttct c.1224+45
--------------------- middle of intron ---------------------
g.16432 . . . . g.16476
c.1225-45 ctccctgcaactggcaggggctgagccagggtcaccctccctcag c.1225-1
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