atonal homolog 1 (Drosophila) (ATOH1) - coding DNA reference sequence

(used for variant description)

(last modified February 12, 2026)

This file was created to facilitate the description of sequence variants on transcript NM_005172.1 in the ATOH1 gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NC_000004.11, covering ATOH1 transcript NM_005172.1.

Please note that introns are available by clicking on the exon numbers above the sequence.

 (upstream sequence)
          .         .         .         .         .         .       g.60
 ATGTCCCGCCTGCTGCATGCAGAAGAGTGGGCTGAAGTGAAGGAGTTGGGAGACCACCAT       c.60
 M  S  R  L  L  H  A  E  E  W  A  E  V  K  E  L  G  D  H  H         p.20

          .         .         .         .         .         .       g.120
 CGCCAGCCCCAGCCGCATCATCTCCCGCAACCGCCGCCGCCGCCGCAGCCACCTGCAACT       c.120
 R  Q  P  Q  P  H  H  L  P  Q  P  P  P  P  P  Q  P  P  A  T         p.40

          .         .         .         .         .         .       g.180
 TTGCAGGCGAGAGAGCATCCCGTCTACCCGCCTGAGCTGTCCCTCCTGGACAGCACCGAC       c.180
 L  Q  A  R  E  H  P  V  Y  P  P  E  L  S  L  L  D  S  T  D         p.60

          .         .         .         .         .         .       g.240
 CCACGCGCCTGGCTGGCTCCCACTTTGCAGGGCATCTGCACGGCACGCGCCGCCCAGTAT       c.240
 P  R  A  W  L  A  P  T  L  Q  G  I  C  T  A  R  A  A  Q  Y         p.80

          .         .         .         .         .         .       g.300
 TTGCTACATTCCCCGGAGCTGGGTGCCTCAGAGGCCGCTGCGCCCCGGGACGAGGTGGAC       c.300
 L  L  H  S  P  E  L  G  A  S  E  A  A  A  P  R  D  E  V  D         p.100

          .         .         .         .         .         .       g.360
 GGCCGGGGGGAGCTGGTAAGGAGGAGCAGCGGCGGTGCCAGCAGCAGCAAGAGCCCCGGG       c.360
 G  R  G  E  L  V  R  R  S  S  G  G  A  S  S  S  K  S  P  G         p.120

          .         .         .         .         .         .       g.420
 CCGGTGAAAGTGCGGGAACAGCTGTGCAAGCTGAAAGGCGGGGTGGTGGTAGACGAGCTG       c.420
 P  V  K  V  R  E  Q  L  C  K  L  K  G  G  V  V  V  D  E  L         p.140

          .         .         .         .         .         .       g.480
 GGCTGCAGCCGCCAACGGGCCCCTTCCAGCAAACAGGTGAATGGGGTGCAGAAGCAGAGA       c.480
 G  C  S  R  Q  R  A  P  S  S  K  Q  V  N  G  V  Q  K  Q  R         p.160

          .         .         .         .         .         .       g.540
 CGGCTAGCAGCCAACGCCAGGGAGCGGCGCAGGATGCATGGGCTGAACCACGCCTTCGAC       c.540
 R  L  A  A  N  A  R  E  R  R  R  M  H  G  L  N  H  A  F  D         p.180

          .         .         .         .         .         .       g.600
 CAGCTGCGCAATGTTATCCCGTCGTTCAACAACGACAAGAAGCTGTCCAAATATGAGACC       c.600
 Q  L  R  N  V  I  P  S  F  N  N  D  K  K  L  S  K  Y  E  T         p.200

          .         .         .         .         .         .       g.660
 CTGCAGATGGCCCAAATCTACATCAACGCCTTGTCCGAGCTGCTACAAACGCCCAGCGGA       c.660
 L  Q  M  A  Q  I  Y  I  N  A  L  S  E  L  L  Q  T  P  S  G         p.220

          .         .         .         .         .         .       g.720
 GGGGAACAGCCACCGCCGCCTCCAGCCTCCTGCAAAAGCGACCACCACCACCTTCGCACC       c.720
 G  E  Q  P  P  P  P  P  A  S  C  K  S  D  H  H  H  L  R  T         p.240

          .         .         .         .         .         .       g.780
 GCGGCCTCCTATGAAGGGGGCGCGGGCAACGCGACCGCAGCTGGGGCTCAGCAGGCTTCC       c.780
 A  A  S  Y  E  G  G  A  G  N  A  T  A  A  G  A  Q  Q  A  S         p.260

          .         .         .         .         .         .       g.840
 GGAGGGAGCCAGCGGCCGACCCCGCCCGGGAGTTGCCGGACTCGCTTCTCAGCCCCAGCT       c.840
 G  G  S  Q  R  P  T  P  P  G  S  C  R  T  R  F  S  A  P  A         p.280

          .         .         .         .         .         .       g.900
 TCTGCGGGAGGGTACTCGGTGCAGCTGGACGCTCTGCACTTCTCGACTTTCGAGGACAGC       c.900
 S  A  G  G  Y  S  V  Q  L  D  A  L  H  F  S  T  F  E  D  S         p.300

          .         .         .         .         .         .       g.960
 GCCCTGACAGCGATGATGGCGCAAAAGAATTTGTCTCCTTCTCTCCCCGGGAGCATCTTG       c.960
 A  L  T  A  M  M  A  Q  K  N  L  S  P  S  L  P  G  S  I  L         p.320

          .         .         .         .         .         .       g.1020
 CAGCCAGTGCAGGAGGAAAACAGCAAAACTTCGCCTCGGTCCCACAGAAGCGACGGGGAA       c.1020
 Q  P  V  Q  E  E  N  S  K  T  S  P  R  S  H  R  S  D  G  E         p.340

          .         .         .         .                           g.1065
 TTTTCCCCCCATTCCCATTACAGTGACTCGGATGAGGCAAGTTAG                      c.1065
 F  S  P  H  S  H  Y  S  D  S  D  E  A  S  X                        p.354

 

 (downstream sequence)

Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The Atonal homolog 1 (Drosophila) protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.