B-cell receptor-associated protein 31 (BCAP31) - coding DNA reference sequence

(used for variant description)

(last modified November 4, 2020)

This file was created to facilitate the description of sequence variants on transcript NM_001256447.1 in the BCAP31 gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NG_023231.1, covering BCAP31 transcript NM_001256447.1.

Please note that introns are available by clicking on the exon numbers above the sequence.

 (upstream sequence)
                               .         .         .                g.5037
                        accctgttctcgcccctcggcggggcccgcccacacc       c.-421

 .         .         .         .         .         .                g.5097
 cccacctcccgttctcgcccctcggcggggcccctcccgcaccacagagacgtgggacgg       c.-361

 .         .         .         .         .         .                g.5157
 ccgcgcggactagagaagcggccctcgccggcccgacaaagccccgccccgccccgcccg       c.-301

 .         .         .         .         .         .                g.5217
 cgtgctcgctccaccccgccctgctcgcccggagcccgaggcgcctcttcctctcccgct       c.-241

 .         .         .         .         .         .                g.5277
 cggagcgccggccctccgctccggggcggggtgggaagcggaggtgggcggagcctccgg       c.-181

 .         .         .         .         .         .                g.5337
 ggcctcgcgagggctggtgggcggtgcccggcgggcgcttccggtttccggccgcggtat       c.-121

 .         .         .         .         .         .                g.5397
 gaggggcggggccggggctgctgtgggagagttctgttgctgcggcggggcctgcacgtt       c.-61

 .         .      | 02  .         .         .         .             g.6502
 gactgtgggaaactcg | gaaacaagctcacatcttcctgtgggaaaccttctagcaacagg    c.-1

          .         .         .         .         .         .       g.6562
 ATGAGTCTGCAGTGGACTGCAGTTGCCACCTTCCTCTATGCGGAGGTCTTTGTTGTGTTG       c.60
 M  S  L  Q  W  T  A  V  A  T  F  L  Y  A  E  V  F  V  V  L         p.20

          .         .         .   | 03     .         .         .    g.8802
 CTTCTCTGCATTCCCTTCATTTCTCCTAAAAG | ATGGCAGAAGATTTTCAAGTCCCGGCTG    c.120
 L  L  C  I  P  F  I  S  P  K  R  |  W  Q  K  I  F  K  S  R  L      p.40

          .         .         .         .         .         .       g.8862
 GTGGAGTTGTTAGTGTCCTATGGCAACACCTTCTTTGTGGTTCTCATTGTCATCCTTGTG       c.180
 V  E  L  L  V  S  Y  G  N  T  F  F  V  V  L  I  V  I  L  V         p.60

          .    | 04    .         .         .         .         .    g.14104
 CTGTTGGTCATCG | ATGCCGTGCGCGAAATTCGGAAGTATGATGATGTGACGGAAAAGGTG    c.240
 L  L  V  I  D |   A  V  R  E  I  R  K  Y  D  D  V  T  E  K  V      p.80

          .         .         .         .         .         .       g.14164
 AACCTCCAGAACAATCCCGGGGCCATGGAGCACTTCCACATGAAGCTTTTCCGTGCCCAG       c.300
 N  L  Q  N  N  P  G  A  M  E  H  F  H  M  K  L  F  R  A  Q         p.100

          .         .         .         .  | 05      .         .    g.25671
 AGGAATCTCTACATTGCTGGCTTTTCCTTGCTGCTGTCCTT | CCTGCTTAGACGCCTGGTG    c.360
 R  N  L  Y  I  A  G  F  S  L  L  L  S  F  |  L  L  R  R  L  V      p.120

          .         .         .         .         .         .       g.25731
 ACTCTCATTTCGCAGCAGGCCACGCTGCTGGCCTCCAATGAAGCCTTTAAAAAGCAGGCG       c.420
 T  L  I  S  Q  Q  A  T  L  L  A  S  N  E  A  F  K  K  Q  A         p.140

          .         .         .         .         .        | 06.    g.26691
 GAGAGTGCTAGTGAGGCGGCCAAGAAGTACATGGAGGAGAATGACCAGCTCAAGAAG | GGA    c.480
 E  S  A  S  E  A  A  K  K  Y  M  E  E  N  D  Q  L  K  K   | G      p.160

          .         .         .         .         .         .       g.26751
 GCTGCTGTTGACGGAGGCAAGTTGGATGTCGGGAATGCTGAGGTGAAGTTGGAGGAAGAG       c.540
 A  A  V  D  G  G  K  L  D  V  G  N  A  E  V  K  L  E  E  E         p.180

          .         .         .         .         .         .       g.26811
 AACAGGAGCCTGAAGGCTGACCTGCAGAAGCTAAAGGACGAGCTGGCCAGCACTAAGCAA       c.600
 N  R  S  L  K  A  D  L  Q  K  L  K  D  E  L  A  S  T  K  Q         p.200

   | 07      .         .         .         .         .         .    g.27698
 A | AACTAGAGAAAGCTGAAAACCAGGTTCTGGCCATGCGGAAGCAGTCTGAGGGCCTCACC    c.660
 K |   L  E  K  A  E  N  Q  V  L  A  M  R  K  Q  S  E  G  L  T      p.220

          .         .         .         .   | 08     .         .    g.28789
 AAGGAGTACGACCGCTTGCTGGAGGAGCACGCAAAGCTGCAG | GCTGCAGTAGATGGTCCC    c.720
 K  E  Y  D  R  L  L  E  E  H  A  K  L  Q   | A  A  V  D  G  P      p.240

          .         .                                               g.28810
 ATGGACAAGAAGGAAGAGTAA                                              c.741
 M  D  K  K  E  E  X                                                p.246

          .         .         .         .         .         .       g.28870
 gggcctccttcctcccctgcctgcagctggcttccacctggcacgtgcctgctgcttcct       c.*60

          .         .         .         .         .         .       g.28930
 gagagcccggcctctccctccagtacttctgtttgtgcccttctgcttcccccattccct       c.*120

          .         .         .         .         .         .       g.28990
 tccacagctcatagctcgtcatctcggcccttgtccacactctccaagcacattacaggg       c.*180

          .         .         .         .         .         .       g.29050
 gacctgattgctacacgttcagaatgcgtttgctgtcatcctgcttggcctggccaggcc       c.*240

          .         .         .         .         .         .       g.29110
 tggcacagccttggcttccacgcctgagcgtggagagcacgagttagttgtagtccggct       c.*300

          .         .         .         .         .         .       g.29170
 tgcggtggggctgacttcctgttggtttgagcccctttttgttttgccctctgggtgttt       c.*360

          .         .         .         .         .         .       g.29230
 tctttggtcccgcaggagggtgggtggagcaggtggactggagtttctcttgagggcaat       c.*420

          .         .                                               g.29255
 aaaagttgtcatggtgtgtacgtgg                                          c.*445

 (downstream sequence)

Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The B-cell receptor-associated protein 31 protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.