(intronic numbering for coding DNA Reference Sequence)
. . . . g.22220
gtggggctgtgttcagtgtcccaaggaagtggggggtcaaagggac c.7590+46
--------------------- middle of intron ---------------------
g.22221 . . . . g.22266
c.7591-46 acggggattctgcccaacaacccatcaaccatccctgtctctgtag c.7591-1
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