carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 (CHST6) - coding DNA reference sequence

(used for variant description)

(last modified June 24, 2017)
This file was created to facilitate the description of sequence variants on transcript NM_021615.4 in the CHST6 gene based on a coding DNA reference sequence following the HGVS recommendations.
The sequence was taken from NG_016442.1, covering CHST6 transcript NM_021615.4.
Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
 .         .         .         .         .         .                g.5060
 gacgacgtttgggagcctttgctgagtccagggagagaggcgtcccccaccgtgccgctg       c.-121

 .         .         .         | 02         .         .             g.18168
 cagctcgggcagagccgccaagctttggg | gtgctgaggaacctctaatcatctcccatgg    c.-61

 .         .         .         .         .    | 03    .             g.20200
 atttgtgatcagcgttgcagctctcccagcagccctggacagtg | gcccccagcagtcagc    c.-1

          .         .         .         .         .         .       g.20260
 ATGTGGCTGCCGCGCGTCTCCAGCACAGCAGTGACCGCGCTCCTCCTGGCGCAGACCTTC       c.60
 M  W  L  P  R  V  S  S  T  A  V  T  A  L  L  L  A  Q  T  F         p.20

          .         .         .         .         .         .       g.20320
 CTCCTCCTCTTTCTGGTTTCCCGGCCAGGGCCCTCGTCCCCAGCAGGCGGCGAGGCGCGC       c.120
 L  L  L  F  L  V  S  R  P  G  P  S  S  P  A  G  G  E  A  R         p.40

          .         .         .         .         .         .       g.20380
 GTGCATGTGCTGGTGCTGTCCTCGTGGCGCTCGGGCTCGTCCTTCGTGGGCCAACTCTTC       c.180
 V  H  V  L  V  L  S  S  W  R  S  G  S  S  F  V  G  Q  L  F         p.60

          .         .         .         .         .         .       g.20440
 AACCAGCACCCCGACGTCTTCTACCTAATGGAGCCCGCGTGGCACGTGTGGACCACCCTG       c.240
 N  Q  H  P  D  V  F  Y  L  M  E  P  A  W  H  V  W  T  T  L         p.80

          .         .         .         .         .         .       g.20500
 TCGCAGGGCAGCGCCGCAACGCTGCACATGGCTGTGCGCGACCTGGTGCGCTCCGTCTTC       c.300
 S  Q  G  S  A  A  T  L  H  M  A  V  R  D  L  V  R  S  V  F         p.100

          .         .         .         .         .         .       g.20560
 CTGTGCGACATGGACGTGTTTGATGCCTATCTGCCTTGGCGCCGCAACCTGTCCGACCTC       c.360
 L  C  D  M  D  V  F  D  A  Y  L  P  W  R  R  N  L  S  D  L         p.120

          .         .         .         .         .         .       g.20620
 TTCCAGTGGGCCGTGAGCCGTGCACTGTGCTCGCCACCCGCCTGCAGTGCCTTTCCCCGA       c.420
 F  Q  W  A  V  S  R  A  L  C  S  P  P  A  C  S  A  F  P  R         p.140

          .         .         .         .         .         .       g.20680
 GGCGCCATCAGCAGCGAGGCCGTGTGCAAGCCACTGTGCGCGCGGCAGTCCTTCACCCTG       c.480
 G  A  I  S  S  E  A  V  C  K  P  L  C  A  R  Q  S  F  T  L         p.160

          .         .         .         .         .         .       g.20740
 GCCCGGGAGGCCTGCCGCTCCTACAGCCACGTGGTGCTCAAGGAGGTGCGCTTCTTCAAC       c.540
 A  R  E  A  C  R  S  Y  S  H  V  V  L  K  E  V  R  F  F  N         p.180

          .         .         .         .         .         .       g.20800
 CTGCAGGTGCTCTACCCGCTGCTCAGCGACCCCGCGCTCAACCTACGCATCGTGCACCTG       c.600
 L  Q  V  L  Y  P  L  L  S  D  P  A  L  N  L  R  I  V  H  L         p.200

          .         .         .         .         .         .       g.20860
 GTGCGCGACCCGCGGGCCGTGCTGCGCTCCCGGGAGCAGACAGCCAAGGCTCTGGCGCGT       c.660
 V  R  D  P  R  A  V  L  R  S  R  E  Q  T  A  K  A  L  A  R         p.220

          .         .         .         .         .         .       g.20920
 GACAACGGCATCGTGCTGGGCACCAACGGCACGTGGGTGGAGGCCGACCCCGGCCTGCGC       c.720
 D  N  G  I  V  L  G  T  N  G  T  W  V  E  A  D  P  G  L  R         p.240

          .         .         .         .         .         .       g.20980
 GTGGTGCGCGAGGTGTGCCGTAGCCACGTACGCATCGCCGAGGCCGCCACACTCAAGCCG       c.780
 V  V  R  E  V  C  R  S  H  V  R  I  A  E  A  A  T  L  K  P         p.260

          .         .         .         .         .         .       g.21040
 CCACCCTTTCTGCGCGGCCGCTACCGCCTGGTGCGCTTCGAGGACCTGGCGCGGGAGCCG       c.840
 P  P  F  L  R  G  R  Y  R  L  V  R  F  E  D  L  A  R  E  P         p.280

          .         .         .         .         .         .       g.21100
 CTGGCAGAAATCCGTGCGCTCTACGCCTTCACTGGGCTCAGTCTCACGCCACAGCTCGAG       c.900
 L  A  E  I  R  A  L  Y  A  F  T  G  L  S  L  T  P  Q  L  E         p.300

          .         .         .         .         .         .       g.21160
 GCCTGGATCCATAACATCACCCACGGATCTGGACCTGGTGCGCGCCGCGAAGCCTTCAAG       c.960
 A  W  I  H  N  I  T  H  G  S  G  P  G  A  R  R  E  A  F  K         p.320

          .         .         .         .         .         .       g.21220
 ACTTCGTCCAGGAATGCGCTCAACGTCTCCCAGGCCTGGCGCCATGCGCTGCCCTTTGCC       c.1020
 T  S  S  R  N  A  L  N  V  S  Q  A  W  R  H  A  L  P  F  A         p.340

          .         .         .         .         .         .       g.21280
 AAGATCCGCCGCGTGCAGGAACTGTGCGCTGGTGCGCTGCAGCTGCTGGGCTACCGGCCT       c.1080
 K  I  R  R  V  Q  E  L  C  A  G  A  L  Q  L  L  G  Y  R  P         p.360

          .         .         .         .         .         .       g.21340
 GTGTACTCTGAGGACGAGCAGCGCAACCTCGCCCTTGATCTGGTGCTGCCACGAGGCCTG       c.1140
 V  Y  S  E  D  E  Q  R  N  L  A  L  D  L  V  L  P  R  G  L         p.380

          .         .         .         .                           g.21388
 AACGGCTTCACTTGGGCATCATCCACCGCCTCGCACCCCCGAAATTAG                   c.1188
 N  G  F  T  W  A  S  S  T  A  S  H  P  R  N  X                     p.395

          .         .         .         .         .         .       g.21448
 tggaggccacagttgtagcaggcgctaggcccgggaggagagtgcatggtgcagaggggg       c.*60

          .         .         .         .         .         .       g.21508
 ctggggcgcacggagaagcaggtccctatattgaccaaggagtttgtggtacgacccctc       c.*120

          .         .         .         .         .         .       g.21568
 cccctccccaagtaggcaaggactgcacgtttctttctctcttgattcttggttttcctt       c.*180

          .         .         .         .         .         .       g.21628
 tgagtcctctggagctgccttctcatcaggtgcactcttcatggaaagcaactcttgccc       c.*240

          .         .         .         .         .         .       g.21688
 ctcctcctctgggcacagggtgtgcgttcagatgacttggctcctactcaagggctttct       c.*300

          .         .         .         .         .         .       g.21748
 tcccctttaactctctccttctggtgacacatcctgcagcagctgagggggtgccctggc       c.*360

          .         .         .         .         .         .       g.21808
 actggctgggagtggagaggcactgtggtgaaatggctccagaggtctgtacatcacata       c.*420

          .         .         .         .         .         .       g.21868
 catatgcacacaggcacacatggcaaaactcggaagtgaaaggacttgtctgaaatcaca       c.*480

          .         .         .         .         .         .       g.21928
 tggtgagaaggaggatgaagggaggagagagcttttgctctgggtctccagtggatagga       c.*540

          .         .         .         .         .         .       g.21988
 gaggacctgcctcctgggtgagaagggtcagattttcctattttaattgctttagggaag       c.*600

          .         .         .         .         .         .       g.22048
 agcaagcagagtcatgaccagggacacagctgagagatagaggaggctgtgaatgctgag       c.*660

          .         .         .         .         .         .       g.22108
 accagagtttatcatgctggacaagcctggaaggaggcaataagtgggaaaggtaggagg       c.*720

          .         .         .         .         .         .       g.22168
 agagaaggctggggagggctgggcagcaagccaggcacagtgagtggcagagcaagaggg       c.*780

          .         .         .         .         .         .       g.22228
 ggaaagcaggatcagtgcctggaaggcaggtgtgcccgtcagcggggagtggaactcatc       c.*840

          .         .         .         .         .         .       g.22288
 aggcttgccaagaggttggaagggaaatggctctgggctggaactgtcttcccttggtcc       c.*900

          .         .         .         .         .         .       g.22348
 ttctggtccaggccttggaggaaagcagaggatgatccctgcctgtgagccacacctcct       c.*960

          .         .         .         .         .         .       g.22408
 agctctgggggcaaaggggcttagtaaaggaatgctggatgtgtagagggtttagtcccg       c.*1020

          .         .         .         .         .         .       g.22468
 agctcaggaaatgagagcctataagtgcccagtacatgtttaaaagaagagctcatggaa       c.*1080

          .         .         .         .         .         .       g.22528
 cctctggaaaggacagggaagttgagttagccacataaatgaacccaagtcacattggaa       c.*1140

          .         .         .         .         .         .       g.22588
 cacagagctggtctgggaactgtgttggctgccaacagaacttctgaccctgttacctgt       c.*1200

          .         .         .         .         .         .       g.22648
 gaaatgaggcagtttccctcacgttgccatcagctaccaggagcgatgctggtggtcact       c.*1260

          .         .         .         .         .         .       g.22708
 agcttctgatcctcatcctgggtgtggccacagattgggggaacctggattgtggagtca       c.*1320

          .         .         .         .         .         .       g.22768
 catcctccctgcaaagcaagcagggcaagggagatctggcattttctgctttacgtggag       c.*1380

          .         .         .         .         .         .       g.22828
 ggagaacaggcacattagccttgaagctgaagctcattttaggttccttccaggtttaga       c.*1440

          .         .         .         .         .         .       g.22888
 agcttcaaccaaatgaaacttgaatctgtccctcgtgacaattataggaggaaggtattt       c.*1500

          .         .         .         .         .         .       g.22948
 aaaaccccagatttatgaatgtgtactacatggcttagagaatgtctttgttcttgttca       c.*1560

          .         .         .         .         .         .       g.23008
 ggtggttataacaaaataccttaagagtgggtaacttggctggatgcagtggctcatgcc       c.*1620

          .         .         .         .         .         .       g.23068
 tgtaatcccagcactgtgggaggccgagggggatgaatcacctgaggtcaggcattcaag       c.*1680

          .         .         .         .         .         .       g.23128
 aacagcctggccaacatggcgaagcccctcctctactaaaaatacaaaattagcgaggca       c.*1740

          .         .         .         .         .         .       g.23188
 tggtcgcacatacctgtaatcccagctcctcgggaagctgaggcaggagaatcgcttgaa       c.*1800

          .         .         .         .         .         .       g.23248
 cccaggaggcggaggttgcagtgagccaagatcacgccattgcactccagcctgggtgac       c.*1860

          .         .         .         .         .         .       g.23308
 agagcaagactccatctcaaaaaaaaaaaaaagactgggtaacttataaacaaatgttct       c.*1920

          .         .         .         .         .         .       g.23368
 tctcacaagtctggagactgggaagtccaagatcaagccaccagtgctgtctgatgaggg       c.*1980

          .         .         .         .         .         .       g.23428
 cccactttttcaaagacagtgccttctagctgtgtcctcttatcgtagaagatgggagac       c.*2040

          .         .         .         .         .         .       g.23488
 agctctccagggccatttttttttttttttttttttttttgagatggagtctggctctgt       c.*2100

          .         .         .         .         .         .       g.23548
 cgcccaggctggagtgcagtggcacaatctcggctcactgcaacctctgcctctctctgc       c.*2160

          .         .         .         .         .         .       g.23608
 ctcctgagttcaagcaattctcctgcctcagcctcctgaggagctgggactacagggatg       c.*2220

          .         .         .         .         .         .       g.23668
 caccaccatgcccagctaatttttgtatttttgtagacactgggtttcaccatattggcc       c.*2280

          .         .         .         .         .         .       g.23728
 aggttggtctcaaactcctgacctcaagtgatctgcccacctcagcctcccaaagtgctg       c.*2340

          .         .         .         .         .         .       g.23788
 agattacaggcatgagccactgtacccagtctccagggccttttaaagaatgtcactaat       c.*2400

          .         .         .         .         .         .       g.23848
 cccattcttgaggtctccaccttcattatctaatcacctcccaaaggctccacatcccaa       c.*2460

          .         .         .         .         .         .       g.23908
 caccatcatattgtgggttaagatttcaaccacaagccaggcgtggtggctcatgcctgt       c.*2520

          .         .         .         .         .         .       g.23968
 aatcccagcattttggaaggctgaggcaggtggatcacttgaggtcaggagtttgagacc       c.*2580

          .         .         .         .         .         .       g.24028
 agcctggccaacatggtgaaaccccatctctactaaaaataaaaaaaattagccgggtgt       c.*2640

          .         .         .         .         .         .       g.24088
 ggtggtgcacacctgtaattccagctactcaggaggctgaggcaggagaatcccttgaat       c.*2700

          .         .         .         .         .         .       g.24148
 ccaggaggcggacagtgcagtgagccgagataatgccactgcactccagcctggatgaca       c.*2760

          .         .         .         .         .         .       g.24208
 gagcaagactccatctcatgcccagccagcatgcccaacaagcttcatttgcccctgttt       c.*2820

          .         .         .         .         .         .       g.24268
 aggtcacaaattttattgatggctgcaattaatggcctcttggtatccaagtcctttgtt       c.*2880

          .         .         .         .         .         .       g.24328
 gtatgacccatccattctcccctgactcccaaggtgtcaggacatgcttgactggctcct       c.*2940

          .         .         .         .         .         .       g.24388
 gaatttgctctctgcgcatgggcagtacagtcaagcctcacagtgaacccaggtcagctt       c.*3000

          .         .         .         .         .         .       g.24448
 tcaggacaaagaaagtggcctggctgactaggcacagtaaagccagggctgggtaggtac       c.*3060

          .         .         .         .         .         .       g.24508
 atacttgtgctgatcacgtatgtcttatatctctgtgagagtgcagtcccaacaggaagg       c.*3120

          .         .         .         .         .         .       g.24568
 tttaatcactggggactgcccaatgctgtgacagggcacagagctctgggttgctgtggg       c.*3180

          .         .         .         .         .         .       g.24628
 ggtgactgcattgaccactgttagtggtttgctgtgttgacactctgtgctgtgtgacca       c.*3240

          .         .         .         .         .         .       g.24688
 tggctcctgccatcaagaagtagagtctgtttctccacctctgaatccaggctggtcctg       c.*3300

          .         .         .         .         .         .       g.24748
 tgacttgctttgtcctgtagacaagtgtagtgcaacttcctgtgagccagtttgaagcat       c.*3360

          .         .         .         .         .         .       g.24808
 aggccttggaagcaaaactttacctccacctgtcttaggttttcagctggggctctgctg       c.*3420

          .         .         .         .         .         .       g.24868
 tgatttgattgtgtctcccaaagttggaaccttgatccccagtgttgtgaggtgaggctt       c.*3480

          .         .         .         .         .         .       g.24928
 gatggaaagtaaattacgccgtgcgggttatgcccttgtgaatgggtagagaacattatt       c.*3540

          .         .         .         .         .         .       g.24988
 tctgggcgcaggcatggtagctcatgtctgtaatcccagcattttgggaggttgaggtgt       c.*3600

          .         .         .         .         .         .       g.25048
 gcggattacttgaggtcaggagtttgagaccagcctggccaacaaggtaaaacaccattt       c.*3660

          .         .         .         .         .         .       g.25108
 ctagttaaaatacaaaaattagccaggtgtggtggcacatgcctgtaaggccagctactt       c.*3720

          .         .         .         .         .         .       g.25168
 gggaggctgagacaggagaatcgcttgaacccaggaggcagagattgcagtgagctgaga       c.*3780

          .         .         .         .         .         .       g.25228
 tcgcaccactgtactccagcctgggcaacaaagcgagagtctgtcttaaaaaaaaccacc       c.*3840

          .         .         .         .         .         .       g.25288
 attatttcaggagtgagttggttatcctgagagtggtgccttttaaatgaaggagttcat       c.*3900

          .         .         .         .         .         .       g.25348
 tctttgtctttctctcgccctcactttgcccttctgccatatgatgccttccatcatgct       c.*3960

          .         .         .         .         .         .       g.25408
 aggacacagcaagaaggctctcgctagatgctggctccttgatcttgggcttcccagcct       c.*4020

          .         .         .         .         .         .       g.25468
 ccagaactgtaagccaatacacttctatttattatatatgacccttgctgggttcagtgg       c.*4080

          .         .         .         .         .         .       g.25528
 ctcacgcctgtaatcccaatactttgcaaggctgaggcaggaggatcacttgagaccagg       c.*4140

          .         .         .         .         .         .       g.25588
 cactcaagaccagcctgggcaacatagtgagaccccatctctacaaagttaaaaaaaaat       c.*4200

          .         .         .         .         .         .       g.25648
 tagcagggcatggtgtcgtgcacctgtagtcctagctacttgggaggctgagttgggagg       c.*4260

          .         .         .         .         .         .       g.25708
 actgcttgaccctgggaggttgaggctacattgaaccatgatcatgccagtgcactccag       c.*4320

          .         .         .         .         .         .       g.25768
 cctgagtgacagagcaagacacctatctctaaataaatgaccccatctgtggtattgtta       c.*4380

          .         .         .         .         .         .       g.25828
 tagcaaaacaaaacagattaagagagactttttaatgaaaagacagattcacaaagaaaa       c.*4440

          .         .         .         .         .         .       g.25888
 acaatgtttttgtttctgtttttttgaggcagagtcttgctcttgtcccccaggctggag       c.*4500

          .         .         .         .         .         .       g.25948
 tgcagtggcgccatcttggctcactgcaacctccgcctcccagtttcaagcgattctcct       c.*4560

          .         .         .         .         .         .       g.26008
 gcctcagcctcccgagtagctgggattacagatgtacaccaccacgcccggctaattttt       c.*4620

          .         .         .         .         .         .       g.26068
 tttgtatttttagtagagatggggtttcaccatgtcgatcaggctgggctggaactcctg       c.*4680

          .         .         .         .         .         .       g.26128
 acctcaggtgatccacctgccttggcctcccaatgtgctaggattacaggcatgagccac       c.*4740

          .         .         .         .         .         .       g.26188
 tgtacctggcgaaaaacagtttgttaacacaggcagccaacatcactcaggataagcctc       c.*4800

          .         .         .         .         .         .       g.26248
 aatgaaaagtaacaaagtgatggcttggaacactgtcttacacagcatttttaaaaaata       c.*4860

          .         .         .         .         .         .       g.26308
 caataaatttgtagagataggatgaccaaggacaacagttttaggcttccaaaggtggta       c.*4920

          .         .         .         .         .         .       g.26368
 aactatgggatggtaaatatccgagaggaagctgatgcaacaggatttgtctgcagcagc       c.*4980

          .         .         .         .         .         .       g.26428
 ctctggtaccacctctgagtcaagggttgtgtccagtgatggagagtttatatcgtgcct       c.*5040

          .         .         .         .         .         .       g.26488
 ttaggcagaaaaggggagggaaacctgaacttttcctgcactttctgcttcttaattgcc       c.*5100

          .         .         .         .         .         .       g.26548
 ttcagctgaaaatcattttttatgtgaaaaaggcatagtctgagctgacgcctctgcttt       c.*5160

          .         .         .         .         .         .       g.26608
 cctccacctgaagagaacctgcgtgctgctcctttgcttcggacctccgcctctgcccgg       c.*5220

          .         .         .         .         .         .       g.26668
 gagaaagcccaggccagcctgctggacaagcagagaccatgagaaggagagttcaggggt       c.*5280

          .         .         .         .         .         .       g.26728
 cccaaaccaggccatcctagaccagccagctccagctgatccgcacgcagccacttcggc       c.*5340

          .         .         .         .         .         .       g.26788
 taccttctactggccaaagggagtcccagggctcacccagattcagaggtggggaaactg       c.*5400

          .         .         .         .         .         .       g.26848
 agtccaccacttgagaagagtagctataaagacatatgagcgaggccagctgagcccagc       c.*5460

          .         .         .         .         .                 g.26905
 actgcggccaagtcgaagactttaggagcaataaaagtgcttattgtgtttcagtca          c.*5517

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.