DnaJ (Hsp40) homolog, subfamily C, member 5 (DNAJC5) - coding DNA reference sequence

(used for variant description)

(last modified November 10, 2016)
This file was created to facilitate the description of sequence variants on transcript NM_025219.2 in the DNAJC5 gene based on a coding DNA reference sequence following the HGVS recommendations.
The sequence was taken from NG_029805.1, covering DNAJC5 transcript NM_025219.2.
Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
           .         .         .         .         .                g.5053
        gggagcgcgcgcgccggtgcgggtgcgtgcgtgagcgtgctcgtctccgctgc       c.-181

 .         .         .         .         .         .                g.5113
 cgctgccgctgccgctgccggtgccgcacccgcgccctctgccgccgccgccgccgccgc       c.-121

 .         .         .         .         .         .                g.5173
 ccggggtctccaggctgaggagtgcgtcggccgctgcccagcagcgccgcgaatcgggga       c.-61

 .         .         .         .         .         | 02             g.38244
 gcggagccgcggagccggcgggagggcgggcgggcgggcggacgggcag | aatagcctaac    c.-1

          .         .         .         .         .         .       g.38304
 ATGGCAGACCAGAGACAGCGCTCACTGTCTACCTCTGGGGAGTCATTGTACCACGTCCTT       c.60
 M  A  D  Q  R  Q  R  S  L  S  T  S  G  E  S  L  Y  H  V  L         p.20

          .         .         .         .        | 03.         .    g.39223
 GGGTTGGACAAGAACGCAACCTCAGATGACATTAAAAAGTCCTATCG | GAAGCTTGCCTTG    c.120
 G  L  D  K  N  A  T  S  D  D  I  K  K  S  Y  R  |  K  L  A  L      p.40

          .         .         .         .         .         .       g.39283
 AAATATCACCCCGACAAGAACCCCGACAACCCGGAGGCCGCGGACAAGTTTAAGGAGATC       c.180
 K  Y  H  P  D  K  N  P  D  N  P  E  A  A  D  K  F  K  E  I         p.60

          .         .         .         .         .         .       g.39343
 AACAACGCGCACGCCATCCTCACGGACGCCACAAAAAGGAACATCTACGACAAGTACGGC       c.240
 N  N  A  H  A  I  L  T  D  A  T  K  R  N  I  Y  D  K  Y  G         p.80

          .         .         .         .         .         .       g.39403
 TCGCTGGGTCTCTACGTGGCCGAGCAGTTTGGGGAAGAGAACGTGAACACCTACTTCGTG       c.300
 S  L  G  L  Y  V  A  E  Q  F  G  E  E  N  V  N  T  Y  F  V         p.100

          .         .  | 04      .         .         .         .    g.40788
 CTGTCCAGCTGGTGGGCCAAG | GCCCTGTTTGTCTTCTGCGGCCTCCTCACGTGCTGCTAC    c.360
 L  S  S  W  W  A  K   | A  L  F  V  F  C  G  L  L  T  C  C  Y      p.120

          .         .         .         .         .         .       g.40848
 TGCTGCTGCTGTCTGTGCTGCTGCTTCAACTGCTGCTGCGGGAAGTGTAAGCCCAAGGCG       c.420
 C  C  C  C  L  C  C  C  F  N  C  C  C  G  K  C  K  P  K  A         p.140

          .         .         .         .         .         .       g.40908
 CCTGAAGGCGAGGAGACGGAGTTCTACGTGTCCCCCGAGGATCTGGAGGCACAGCTGCAG       c.480
 P  E  G  E  E  T  E  F  Y  V  S  P  E  D  L  E  A  Q  L  Q         p.160

          .    | 05    .         .         .         .         .    g.41410
 TCTGACGAGAGGG | AGGCCACAGACACGCCGATCGTCATACAGCCGGCATCCGCCACCGAG    c.540
 S  D  E  R  E |   A  T  D  T  P  I  V  I  Q  P  A  S  A  T  E      p.180

          .         .         .         .         .                 g.41467
 ACCACCCAGCTCACAGCCGACTCCCACCCCAGCTACCACACTGACGGGTTCAACTAA          c.597
 T  T  Q  L  T  A  D  S  H  P  S  Y  H  T  D  G  F  N  X            p.198

          .         .         .         .         .         .       g.41527
 atccaggaggagctgtggtcagaggaggagccggcgcctggccacgccaaccttagaatc       c.*60

          .         .         .         .         .         .       g.41587
 atgaactgtagtcacagagatgggaaggcagcctcctgcctgccctggccttgctggggc       c.*120

          .         .         .         .         .         .       g.41647
 ccctcctgcctccacgcccacccagcgtcgacccttgacccacgaagtgcgtagcatgca       c.*180

          .         .         .         .         .         .       g.41707
 gtatttaaagcagtgtagctacggtcttctgtttttttcccttttttaatagcatgtatg       c.*240

          .         .         .         .         .         .       g.41767
 gggttctgttccatgtctgtgttgtggacattccgcggcatgaccgcgtgaactgcacgg       c.*300

          .         .         .         .         .         .       g.41827
 tggagctgcctcagggctgtcggtcaggttggtccagtgaggggtgactgcagccggtca       c.*360

          .         .         .         .         .         .       g.41887
 ggtgggcgaggagaaggggggctgcccctttcctacctgtgcttgaggggccggaggcag       c.*420

          .         .         .         .         .         .       g.41947
 gtgctgcctggcagagctgtgttaccgtcttggcctcggggtctggtccacactctgtgc       c.*480

          .         .         .         .         .         .       g.42007
 tcccagccttgaggctgcagtaggactctgatctcacctgccagaagagaggcggggccg       c.*540

          .         .         .         .         .         .       g.42067
 cgtcctcctggcgtcaccggcgtcactgtcattccttggtgtctgtgctgggcatggttg       c.*600

          .         .         .         .         .         .       g.42127
 gcttgggggtctgtggtttcctgggccttgtggcagggtttctcccgtgggagaatttgg       c.*660

          .         .         .         .         .         .       g.42187
 tgtggaaagcataggaggccccttccgaggttgacaccgtgtcctccgcggtgtttctcg       c.*720

          .         .         .         .         .         .       g.42247
 cctggtcgtctcgtcgtgtggacgctgccgttctggttctcggaggtgtgtccttcgccg       c.*780

          .         .         .         .         .         .       g.42307
 tgttggggttatttgtctgtgttcctgcacttttcccgggctctgagctggattgatggg       c.*840

          .         .         .         .         .         .       g.42367
 gccagtctcccccctcccatcttgaggtcgttctccacattccttccagcacacctgtcc       c.*900

          .         .         .         .         .         .       g.42427
 tttccatagccctttttggacctttagaaccacagatgataggaccagcccaatgagcca       c.*960

          .         .         .         .         .         .       g.42487
 cagtcagagagtagattgtgcatgtgtgagcacccagctactggggacgggggctctccc       c.*1020

          .         .         .         .         .         .       g.42547
 acgacccctcctcctgtgtttgccagagctcccatctgccccactcgcctttgccccgtc       c.*1080

          .         .         .         .         .         .       g.42607
 atcgatgattcaggcagagccagattcgttaggtccctggaggaaggactgactggacca       c.*1140

          .         .         .         .         .         .       g.42667
 gagggaccctctggctcaggagggttgggtccctgggaggccggcagccaggccacagaa       c.*1200

          .         .         .         .         .         .       g.42727
 tccacacgtggaccattgtgggtccctgggaggccggcagccaggccacggaatccacac       c.*1260

          .         .         .         .         .         .       g.42787
 gtggaccattgtgggtcccttgggaggccagcagccagactacggaatccacatgtggac       c.*1320

          .         .         .         .         .         .       g.42847
 catgggaagtcagtctcttgcgtgtcctagaccttgtgggtggcgccctgcataggggag       c.*1380

          .         .         .         .         .         .       g.42907
 cagggggaacgggtctgatgtccctgtgctggctgagggctcagagctgcccgcactccg       c.*1440

          .         .         .         .         .         .       g.42967
 tagctcatgggatgtgctgggcctgcctttggcgccatgctgcagactccagtgggcctg       c.*1500

          .         .         .         .         .         .       g.43027
 gtttctgcagaatgtccatggtggccgctgcagagttgcagaggtccctgtagagataaa       c.*1560

          .         .         .         .         .         .       g.43087
 gctgaggaggaggctgtgtgtgatggctctggctcggaccaaccagatgagcctcctgaa       c.*1620

          .         .         .         .         .         .       g.43147
 gcccccttccctgcctgcctgctgacccgtggccccagctcactcattgccctcagcagc       c.*1680

          .         .         .         .         .         .       g.43207
 cacccgaggctgtgcagaagggtaggttcaggttgaccaggaagctgccaaaagggacat       c.*1740

          .         .         .         .         .         .       g.43267
 ggatatgaggatacatctggacgtgcttaggaacagggtgctggttgagggcccccagct       c.*1800

          .         .         .         .         .         .       g.43327
 gacccctactgcagatccgcatgtggaccatgagccggctgccagcactaggtcctgggc       c.*1860

          .         .         .         .         .         .       g.43387
 agctttgtttgtcccacttttctttgtttcttctcactaaaatgatcacgaagacctttg       c.*1920

          .         .         .         .         .         .       g.43447
 acaagaggagagatatgcactgtgatattaaattagaaataatttatcaaaatcagacct       c.*1980

          .         .         .         .         .         .       g.43507
 ctcctaaaagaataagaaattcattgtttggcccatcctgaaaggtgaggtggcgagaca       c.*2040

          .         .         .         .         .         .       g.43567
 gtggggtgcctccgtgccgcttcgtgcagcagcaagttcagcctgagatgctggctgtac       c.*2100

          .         .         .         .         .         .       g.43627
 tcagcctttgcaatttttgtagatgtagcttaggacgtgagttatttttccgcagactgg       c.*2160

          .         .         .         .         .         .       g.43687
 ccaagagccaggttctaagcttggacctaaggtagaaagctgcccatcgggggccctagc       c.*2220

          .         .         .         .         .         .       g.43747
 tcagccccaccaggccctctgttgggcctgcacacagctctgtggctagaacactccaag       c.*2280

          .         .         .         .         .         .       g.43807
 gcccttcggtacccatcagagtgggccccttgccaggtggcttttcagttacagagtcca       c.*2340

          .         .         .         .         .         .       g.43867
 gtggaccattttgtagaaccatgcagctccctgcggaaggtggggtagggtgggaaagag       c.*2400

          .         .         .         .         .         .       g.43927
 gagcaggtctggaggtttgtggaacccagtcccctgcagaatctgtaaaacctaataaat       c.*2460

          .         .         .         .         .         .       g.43987
 catggttgtggccattctcacggtggtgattgtgattagacgacccccgggaagcccaga       c.*2520

          .         .         .         .         .         .       g.44047
 cactcggggcctggagttcctccccctgcctgacctagaagcagaaccgttttcagcgct       c.*2580

          .         .         .         .         .         .       g.44107
 ctgccctgttggctttaaggctttgtcttaatttaaggaaaaagatcctcccgggtttta       c.*2640

          .         .         .         .         .         .       g.44167
 tttctctctttcttgagtggactgtttccctataattaaaagaggtggtgagtcctgggg       c.*2700

          .         .         .         .         .         .       g.44227
 cagcttccgcgcctccctgtccacgtgctaacagatcaggacgcccccagcacccctgcc       c.*2760

          .         .         .         .         .         .       g.44287
 tgcttttgctggtggcagtgacgggaccccgactcctcactctcgggccgcagacaatgc       c.*2820

          .         .         .         .         .         .       g.44347
 tgtgagcaagtgtggccatgggcacagaatgtccctttggacgccgctgctgggggctgc       c.*2880

          .         .         .         .         .         .       g.44407
 caggggccctctggggtcgtgctttgaggcccgtccggttcacgagggggtccgggcagc       c.*2940

          .         .         .         .         .         .       g.44467
 actgactgcttccgacctgcaggaggcgtaggagcggccctgcgggccctttcacggcag       c.*3000

          .         .         .         .         .         .       g.44527
 ctgctgctgtatagatttgtctccactcagtgacgtgggatttttttgtcttccttttgg       c.*3060

          .         .         .         .         .         .       g.44587
 ctttatttttaaactgctttagatattactgctcagtgtttgtgaactttcctagttctc       c.*3120

          .         .         .         .         .         .       g.44647
 tatgttgttagtgcagccagcacccagtggggacctactagaaaaaggaactggcatgca       c.*3180

          .         .         .         .         .         .       g.44707
 cacgtgcccagcaggaaaagcttcgtcttcacgtcggctgctgccatccagaagaggccc       c.*3240

          .         .         .         .         .         .       g.44767
 tggagcctcacgccgtcgaggctgctctcaggcgttctgttccgggcgaggcttgtgctg       c.*3300

          .         .         .         .         .         .       g.44827
 caaggaagggcaccagcatgcaggctgccactggagggtccgggtgctgcgggcagagtt       c.*3360

          .         .         .         .         .         .       g.44887
 cagcgcttgtccaccctcccttagctctgactcagtgcatcctactgtggggacatctcg       c.*3420

          .         .         .         .         .         .       g.44947
 tgaggggacacgaaatgactgatctcaccctttcccagtattcagagctgtgaacccctg       c.*3480

          .         .         .         .         .         .       g.45007
 tggcgcaggactggcctgtgtctgttattttggttgtaaatcattctcctgtggaattgg       c.*3540

          .         .         .         .         .         .       g.45067
 caaaagctacatttttactgtccttaccagcaacagtttgcgtcgtcacatgctgtgagt       c.*3600

          .         .         .         .         .         .       g.45127
 gtgggctgtggtgtgtccgtgtgtgtacatatgtgtatatgtatatatcacgcagcagga       c.*3660

          .         .         .         .         .         .       g.45187
 gtgtcattcatgctgctgtcccctggtgaagtgacaagtacaattaaaggtggctctgaa       c.*3720

          .         .         .         .         .         .       g.45247
 atggcctctggtttcttgggagtcgggcagggacctgcaggaggctttcccagcaggtgc       c.*3780

          .         .         .         .         .         .       g.45307
 acagaaggaagcgctgagcccactgtgtgcagagggtgtgtgcccagggcactgccacgg       c.*3840

          .         .         .         .         .         .       g.45367
 cccccaccagcattggcctctgctctgcagggtggggtgcccatcctgggggctgtgtgt       c.*3900

          .         .         .         .         .         .       g.45427
 catgctcacctgacccaggtgtgtgtcccggtgtgaaatcgaggaggggactggaagccc       c.*3960

          .         .         .         .         .         .       g.45487
 ttccctgccttgaaacatgaaagctgattttctgagcagcagatacggtcagtggcaaag       c.*4020

          .         .         .         .         .         .       g.45547
 ctgcatctgaagggcggcctgggaaggggccctgtgctggccccgggtccgccccagagg       c.*4080

          .         .         .         .         .         .       g.45607
 agtccacacagcaccacctccagaaggggctgggcccggggtcctgcaggcggcaccttt       c.*4140

          .         .         .         .         .         .       g.45667
 tggtagagtttgtttccctggaaaatggggaaaatgtttcaagccaggtgaggggggaag       c.*4200

          .         .         .         .         .         .       g.45727
 ttaacactgaaatatgtattgtttttaaaaatcaaatgcacacgcatggaagctgcttgt       c.*4260

          .         .         .         .         .         .       g.45787
 ccatgcactggttttgtcactggcgtcctggaatccgaccgtgttggggtgcaggcgctg       c.*4320

          .         .         .         .         .         .       g.45847
 tcagactccggctgatcctggctcgagcacacacatctaagggccaggctggttccgcat       c.*4380

          .         .         .         .         .         .       g.45907
 ggtgatctccgtcttgtatgtctgaatgttggcctaaaataaagattactgttgtaaaat       c.*4440

          .         .                                               g.45930
 aaatgttttcactgcggacccca                                            c.*4463

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The DnaJ (Hsp40) homolog, subfamily C, member 5 protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.