dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (DPAGT1) - coding DNA reference sequence

(used for variant description)

(last modified March 20, 2015)


This file was created to facilitate the description of sequence variants on transcript NM_001382.3 in the DPAGT1 gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NG_008918.1, covering DPAGT1 transcript NM_001382.3.


Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
 .         .         .         .         .         .                g.5060
 aagtatccgttcttggctgcctttctttaattgcgtttccagtactctctcggtgattct       c.-361

 .         .         .         .         .         .                g.5120
 actcttgaacataggatgaaatttggaatcacacttctcttccacttccatccccaccct       c.-301

 .         .         .         .         .         .                g.5180
 ctaatgcccatattaaaaatggcggccgccgccttccgcagtaatggttgttcagcgaac       c.-241

 .         .         .         .         .         .                g.5240
 aagatccgggcggaaacagtagataggcgggtgcagcggggcagaacataggttgcctta       c.-181

 .         .         .         .         .         .                g.5300
 gagaggttccccggtgtcccgacggcggctcaagtcagagttgctgggttttgctcagat       c.-121

 .         .         .         .         .         .                g.5360
 tggtgtgggaagagcctgcctgtggggagcggccactccatactgctgaggcctcaggac       c.-61

 .         .         .         .         .         .                g.5420
 tgctgctcagcttgcccgttacctgaagaggcggcggagccgggcccctgaccggtcacc       c.-1

          .         .         .         .         .         .       g.5480
 ATGTGGGCCTTCTCGGAATTGCCCATGCCGCTGCTGATCAATTTGATCGTCTCGCTGCTG       c.60
 M  W  A  F  S  E  L  P  M  P  L  L  I  N  L  I  V  S  L  L         p.20

          .         .         .         .         .         .       g.5540
 GGATTTGTGGCCACAGTCACCCTCATCCCGGCCTTCCGGGGCCACTTCATTGCTGCGCGC       c.120
 G  F  V  A  T  V  T  L  I  P  A  F  R  G  H  F  I  A  A  R         p.40

          .         .         .         .  | 02      .         .    g.5956
 CTCTGTGGTCAGGACCTCAACAAAACCAGCCGACAGCAGAT | CCCAGAATCCCAGGGAGTG    c.180
 L  C  G  Q  D  L  N  K  T  S  R  Q  Q  I  |  P  E  S  Q  G  V      p.60

          .         .         .         .         .         .       g.6016
 ATCAGCGGTGCTGTTTTCCTTATCATCCTCTTCTGCTTCATCCCTTTCCCCTTCCTGAAC       c.240
 I  S  G  A  V  F  L  I  I  L  F  C  F  I  P  F  P  F  L  N         p.80

          .         .         .         .   | 03     .         .    g.6250
 TGCTTTGTGAAGGAGCAGTGTAAGGCATTCCCCCACCATGAA | TTTGTGGCCCTGATAGGT    c.300
 C  F  V  K  E  Q  C  K  A  F  P  H  H  E   | F  V  A  L  I  G      p.100

          .         .         .         .         .         .       g.6310
 GCCCTCCTTGCCATCTGCTGCATGATCTTCCTGGGCTTTGCGGATGATGTACTGAATCTG       c.360
 A  L  L  A  I  C  C  M  I  F  L  G  F  A  D  D  V  L  N  L         p.120

          .         .         .         .         .         .       g.6370
 CGCTGGCGCCATAAGCTGCTGCTACCTACAGCTGCCTCACTACCTCTCCTCATGGTCTAT       c.420
 R  W  R  H  K  L  L  L  P  T  A  A  S  L  P  L  L  M  V  Y         p.140

          .         .         .         .         .         .       g.6430
 TTCACCAACTTTGGCAACACGACCATTGTGGTGCCCAAGCCCTTCCGCCCGATACTTGGC       c.480
 F  T  N  F  G  N  T  T  I  V  V  P  K  P  F  R  P  I  L  G         p.160

          .       | 04 .         .         .         .         .    g.6711
 CTGCATCTGGACTTGG | GAATCCTGTACTATGTCTACATGGGGCTGCTGGCAGTGTTCTGT    c.540
 L  H  L  D  L  G |   I  L  Y  Y  V  Y  M  G  L  L  A  V  F  C      p.180

          .         .         .         .         .         .       g.6771
 ACCAATGCCATCAATATCCTAGCAGGAATTAACGGCCTAGAGGCTGGCCAGTCACTAGTC       c.600
 T  N  A  I  N  I  L  A  G  I  N  G  L  E  A  G  Q  S  L  V         p.200

          .         .         .         .    | 05    .         .    g.8605
 ATTTCTGCTTCCATCATTGTCTTCAACCTGGTAGAGTTGGAAG | GTGATTGTCGGGATGAT    c.660
 I  S  A  S  I  I  V  F  N  L  V  E  L  E  G |   D  C  R  D  D      p.220

          .         .         .         .         .         .       g.8665
 CATGTCTTTTCCCTCTACTTCATGATACCCTTTTTTTTCACCACTTTGGGATTGCTCTAC       c.720
 H  V  F  S  L  Y  F  M  I  P  F  F  F  T  T  L  G  L  L  Y         p.240

          | 06         .         .         .         .         .    g.9084
 CACAACTG | GTACCCATCACGGGTGTTTGTGGGAGATACCTTCTGTTACTTTGCTGGCATG    c.780
 H  N  W  |  Y  P  S  R  V  F  V  G  D  T  F  C  Y  F  A  G  M      p.260

          .         .         .         .         .         .       g.9144
 ACCTTTGCCGTGGTGGGCATCTTGGGACACTTCAGCAAGACCATGCTACTATTCTTCATG       c.840
 T  F  A  V  V  G  I  L  G  H  F  S  K  T  M  L  L  F  F  M         p.280

          .         .         .         .         .         .       g.9204
 CCCCAGGTGTTCAACTTCCTCTACTCACTGCCTCAGCTCCTGCATATCATCCCCTGCCCT       c.900
 P  Q  V  F  N  F  L  Y  S  L  P  Q  L  L  H  I  I  P  C  P         p.300

          .        | 07.         .         .         .         .    g.9567
 CGCCACCGCATACCCAG | ACTCAATATCAAGACAGGCAAACTGGAGATGAGCTATTCCAAG    c.960
 R  H  R  I  P  R  |  L  N  I  K  T  G  K  L  E  M  S  Y  S  K      p.320

          .         .         .         .      | 08  .         .    g.9793
 TTCAAGACCAAGAGCCTCTCTTTCTTGGGCACCTTTATTTTAAAG | GTGGCAGAGAGCCTC    c.1020
 F  K  T  K  S  L  S  F  L  G  T  F  I  L  K   | V  A  E  S  L      p.340

          .         .         .         .         .         .       g.9853
 CAGCTGGTGACAGTACACCAGAGTGAGACTGAAGATGGTGAATTCACTGAATGTAACAAC       c.1080
 Q  L  V  T  V  H  Q  S  E  T  E  D  G  E  F  T  E  C  N  N         p.360

          .         .         .         .         .         .       g.9913
 ATGACCCTCATCAACTTGCTACTTAAAGTCCTTGGGCCCATACATGAGAGAAACCTCACA       c.1140
 M  T  L  I  N  L  L  L  K  V  L  G  P  I  H  E  R  N  L  T         p.380

          .         .  | 09      .         .         .         .    g.10051
 TTGCTCCTGCTGCTGCTGCAG | ATCCTGGGCAGTGCCATCACCTTCTCCATTCGATATCAG    c.1200
 L  L  L  L  L  L  Q   | I  L  G  S  A  I  T  F  S  I  R  Y  Q      p.400

          .         .                                               g.10078
 CTCGTTCGACTCTTCTATGATGTCTGA                                        c.1227
 L  V  R  L  F  Y  D  V  X                                          p.408

          .         .         .         .         .         .       g.10138
 gtcccttgatcattgtcctttacctcacagtctctaggattcctgactcaggctgacctc       c.*60

          .         .         .         .         .         .       g.10198
 tctctctggtcccagactgcctccttgcccaggcctctctcactcttcatactcctccag       c.*120

          .         .         .         .         .         .       g.10258
 attttgttctcagcattttcctttctctgtgatcattggcatcctgggcgtttcttgccc       c.*180

          .         .         .         .         .         .       g.10318
 tctgctgactactgattggattttacctatggctttctgcaacttgctactctctccctc       c.*240

          .         .         .         .         .         .       g.10378
 tccatcccatctttgcagcctcatagggtgggatacagcagctttttttgcagttatcca       c.*300

          .         .         .         .         .         .       g.10438
 cactcacatttcagagtcctgactctcaaggaaccactggtttttgggatagaacttggg       c.*360

          .         .         .         .         .         .       g.10498
 ccagggctaggaacacaggctccacggtgacatgtcatttgattgtaaattaagtgttct       c.*420

          .         .         .         .         .         .       g.10558
 gattagtaagaactaagcagggggccacatgctctcaatggagacaataaagtgttgtct       c.*480

          .                                                         g.10573
 ttttcttattgttta                                                    c.*495

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10th nucleotide is indicated by a "." above the sequence. The Dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.

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