FtsJ RNA methyltransferase homolog 1 (E. coli) (FTSJ1) - coding DNA reference sequence

(used for variant description)

(last modified July 20, 2015)

This file was created to facilitate the description of sequence variants on transcript NM_012280.2 in the FTSJ1 gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NG_008879.1, covering FTSJ1 transcript NM_012280.2.

Please note that introns are available by clicking on the exon numbers above the sequence.

 (upstream sequence)
                                         .         .                g.5023
                                      ggatacgtcgacaatagatgacg       c.-301

 .         .         .         .         .         .                g.5083
 gggctcacgttgtacgttcacatcaggtcccggcccgccggaacctgggcgatccacgat       c.-241

 .         .         .         .         .         .                g.5143
 gccgagtttgccacgctgcgacagcccataggcttgcccccccgggcattcgggtggact       c.-181

 .         .         .         .         .         .                g.5203
 acgaacacaaactgaagccctaggacttgtcgcccgtttgcgctctcgccgaggcacagg       c.-121

 .         .         .         .   | 02     .         .             g.6827
 ctgctcgcggaccaccctgctccgaaaactaag | aggtaggtggtagcccattcatctggt    c.-61

 .         .         .         .         .         .                g.6887
 tactgatactggccggcatcagtggactgtcggcaggtccttgagcaactggtgtgtgaa       c.-1

          .         .         .         .         .         .       g.6947
 ATGGGACGGACGTCAAAGGACAAGCGGGATGTCTACTACCGCCTGGCCAAGGAGAATGGC       c.60
 M  G  R  T  S  K  D  K  R  D  V  Y  Y  R  L  A  K  E  N  G         p.20

          .         .         .         .         .         .       g.7007
 TGGCGTGCTCGCAGCGCCTTCAAACTGCTACAACTGGATAAGGAATTCCAACTCTTCCAA       c.120
 W  R  A  R  S  A  F  K  L  L  Q  L  D  K  E  F  Q  L  F  Q         p.40

   | 03      .         .         .         .         .         .    g.7347
 G | GCGTGACACGGGCAGTTGACCTGTGTGCAGCCCCAGGCAGCTGGAGCCAGGTGCTGAGC    c.180
 G |   V  T  R  A  V  D  L  C  A  A  P  G  S  W  S  Q  V  L  S      p.60

          .  | 04      .         .         .         .         .    g.7505
 CAGAAGATCGG | GGGCCAAGGGTCCGGCCACGTGGTGGCTGTGGACCTGCAGGCTATGGCT    c.240
 Q  K  I  G  |  G  Q  G  S  G  H  V  V  A  V  D  L  Q  A  M  A      p.80

          .         .         .         .   | 05     .         .    g.7895
 CCACTACCAGGTGTGGTACAGATCCAGGGGGACATCACCCAG | CTGTCCACTGCCAAGGAG    c.300
 P  L  P  G  V  V  Q  I  Q  G  D  I  T  Q   | L  S  T  A  K  E      p.100

          .         .         .         .         .         .       g.7955
 ATCATCCAGCACTTTAAGGGCTGCCCTGCGGACCTAGTGGTGTGTGACGGGGCTCCTGAT       c.360
 I  I  Q  H  F  K  G  C  P  A  D  L  V  V  C  D  G  A  P  D         p.120

   | 06      .         .         .         .         .     | 07   . g.10134
 G | TAACCGGTCTCCATGATGTTGATGAGTATATGCAGGCCCAGCTCCTCCTAGCT | GCTCTG c.420
 V |   T  G  L  H  D  V  D  E  Y  M  Q  A  Q  L  L  L  A   | A  L   p.140

          .         .         .         .         | 08         .    g.10277
 AACATTGCTACACATGTCCTGAAGCCAGGGGGCTGCTTTGTGGCCAAG | ATATTCCGAGGC    c.480
 N  I  A  T  H  V  L  K  P  G  G  C  F  V  A  K   | I  F  R  G      p.160

          .         .         .         .         .         .       g.10337
 CGGGATGTGACGCTCCTCTACAGCCAGCTGCAGGTCTTCTTCTCCAGCGTGCTGTGTGCC       c.540
 R  D  V  T  L  L  Y  S  Q  L  Q  V  F  F  S  S  V  L  C  A         p.180

          .         .         .  | 09      .         .         .    g.10500
 AAGCCCAGGAGCAGCCGGAACTCTAGCATCG | AGGCCTTCGCTGTCTGTCAGGGCTATGAC    c.600
 K  P  R  S  S  R  N  S  S  I  E |   A  F  A  V  C  Q  G  Y  D      p.200

          .         .         .         .         .      | 10  .    g.11247
 CCTCCCGAGGGCTTCATCCCGGACCTGAGCAAACCCCTGCTGGACCATTCTTACG | ACCCA    c.660
 P  P  E  G  F  I  P  D  L  S  K  P  L  L  D  H  S  Y  D |   P      p.220

          .         .         .         .         .         .       g.11307
 GATTTCAACCAGCTGGATGGTCCCACCCGCATCATTGTGCCTTTTGTGACCTGTGGGGAC       c.720
 D  F  N  Q  L  D  G  P  T  R  I  I  V  P  F  V  T  C  G  D         p.240

          .         .         .          | 11        .         .    g.11457
 CTGAGCTCCTATGATTCGGACCGCAGTTACCCACTGGAC | CTAGAGGGCGGCTCAGAGTAC    c.780
 L  S  S  Y  D  S  D  R  S  Y  P  L  D   | L  E  G  G  S  E  Y      p.260

          .         .         .         .         .         .       g.11517
 AAGTACACTCCACCCACACAGCCCCCCATCTCGCCACCATACCAGGAGGCCTGCACGTTG       c.840
 K  Y  T  P  P  T  Q  P  P  I  S  P  P  Y  Q  E  A  C  T  L         p.280

          .         .         .         .         .         .       g.11577
 AAGAGGAAGGGGCAGCTGGCCAAGGAGATCCGCCCCCAGGACTGCCCCATCAGCAGAGTG       c.900
 K  R  K  G  Q  L  A  K  E  I  R  P  Q  D  C  P  I  S  R  V         p.300

          .         .         .         .         .        | 12.    g.11828
 GACACGTTTCCCCAGCCCCTGGCCGCCCCTCAGTGCCACACCCTGCTGGCCCCTGAG | ATG    c.960
 D  T  F  P  Q  P  L  A  A  P  Q  C  H  T  L  L  A  P  E   | M      p.320

          .         .         .                                 g.11858
 GAAGACAATGAAATGAGTTGTTCACCTTAA |                                  c.991
 E  D  N  E  M  S  C  S  P  X                                    p.329

           | 13        .         .         .         .         .    g.14626
 cccattacg | ctggcaaactgatacaactcagaaactgctcaatgtcaggaaaaccggaac    c.*60

          .         .         .         .         .         .       g.14686
 ttgttgatgaacttgttttcaaaatatcatctcatcaacgaggcctggacaaacaagccc       c.*120

          .         .         .         .         .         .       g.14746
 tgaggagggatctgcaacaaccctgaagacaacaaggaaagaaaccatgaaagtctgtct       c.*180

          .         .         .         .         .         .       g.14806
 gtactgcagtgggaattcttgagtgaggtcttacctcttctttaaacctcttcaggagtg       c.*240

          .         .         .         .         .         .       g.14866
 tcctgattatgtccagaattttccctaaaggcagggattcttaacctggatagaagccag       c.*300

          .         .         .         .         .         .       g.14926
 gggtaaccatgaacttgatggaagaaaatgttacatctttattttcagcaatgaaactga       c.*360

          .         .         .         .         .         .       g.14986
 aatttagccttactcccaagttataaatgctggcaacaaatcacagtagtaaaagcagta       c.*420

          .         .         .         .         .         .       g.15046
 cctgggattttcccaccaatacaaaccagttacagcaactgtaatgtaacataaaaaggg       c.*480

          .         .         .         .         .         .       g.15106
 catcttgaagtattgttcatatttgtcacctcttggaatgatagcagatcctgtaagttg       c.*540

          .         .         .         .         .         .       g.15166
 atgtattaattaaaaagcccatatattactgcatctcaattttgtttcaatttaatatat       c.*600

          .         .         .                                     g.15204
 agtaataattgtaattcaatgtaattggcttccattgt                             c.*638

 (downstream sequence)

Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The FtsJ RNA methyltransferase homolog 1 (E. coli) protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.