glycerol-3-phosphate dehydrogenase 1-like (GPD1L) - coding DNA reference sequence

(used for variant description)

(last modified September 19, 2017)

This file was created to facilitate the description of sequence variants on transcript NM_015141.3 in the GPD1L gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NG_023375.1, covering GPD1L transcript NM_015141.3.

Please note that introns are available by clicking on the exon numbers above the sequence.

 (upstream sequence)
                                         .         .                g.5021
                                        gcagtggttcttgggagtggc       c.-181

 .         .         .         .         .         .                g.5081
 gaagcgggtcctgccccgctgtcagctgcggcccccggcgccgggcgggggtggccgcga       c.-121

 .         .         .         .         .         .                g.5141
 ccattggcggagaggcgaaaggggcggggccgccgccagccgctgcgggcaaggctgaac       c.-61

 .         .         .         .         .         .                g.5201
 aggcggaggtgggcagccggccagggaagcacggtccaggcggctacattcggcccggcc       c.-1

          .         .         .         .        | 02.         .    g.26578
 ATGGCAGCGGCGCCCCTGAAAGTGTGCATCGTGGGCTCGGGGAACTG | GGGTTCAGCTGTT    c.60
 M  A  A  A  P  L  K  V  C  I  V  G  S  G  N  W  |  G  S  A  V      p.20

          .         .         .         .         .         .       g.26638
 GCAAAAATAATTGGTAATAATGTCAAGAAACTTCAGAAATTTGCCTCCACAGTCAAGATG       c.120
 A  K  I  I  G  N  N  V  K  K  L  Q  K  F  A  S  T  V  K  M         p.40

          .         .         .         .         .         .       g.26698
 TGGGTCTTTGAAGAAACAGTGAATGGCAGAAAACTGACAGACATCATAAATAATGACCAT       c.180
 W  V  F  E  E  T  V  N  G  R  K  L  T  D  I  I  N  N  D  H         p.60

          .         .         .         .      | 03  .         .    g.37091
 GAAAATGTAAAATATCTTCCTGGACACAAGCTGCCAGAAAATGTG | GTTGCCATGTCAAAT    c.240
 E  N  V  K  Y  L  P  G  H  K  L  P  E  N  V   | V  A  M  S  N      p.80

          .         .         .         .         .         .       g.37151
 CTTAGCGAGGCTGTGCAGGATGCAGACCTGCTGGTGTTTGTCATTCCCCACCAGTTCATT       c.300
 L  S  E  A  V  Q  D  A  D  L  L  V  F  V  I  P  H  Q  F  I         p.100

          .         .         .         .         .         .       g.37211
 CACAGAATCTGTGATGAGATCACTGGGAGAGTGCCCAAGAAAGCGCTGGGAATCACCCTC       c.360
 H  R  I  C  D  E  I  T  G  R  V  P  K  K  A  L  G  I  T  L         p.120

        | 04 .         .         .         .         .         .    g.38771
 ATCAAG | GGCATAGACGAGGGCCCCGAGGGGCTGAAGCTCATTTCTGACATCATCCGTGAG    c.420
 I  K   | G  I  D  E  G  P  E  G  L  K  L  I  S  D  I  I  R  E      p.140

          .         .         .         .         .         .       g.38831
 AAGATGGGTATTGACATCAGTGTGCTGATGGGAGCCAACATTGCCAATGAGGTGGCTGCA       c.480
 K  M  G  I  D  I  S  V  L  M  G  A  N  I  A  N  E  V  A  A         p.160

          .         .      | 05  .         .         .         .    g.45146
 GAGAAGTTCTGTGAGACCACCATCG | GCAGCAAAGTAATGGAGAACGGCCTTCTCTTCAAA    c.540
 E  K  F  C  E  T  T  I  G |   S  K  V  M  E  N  G  L  L  F  K      p.180

          .         .         .         .         .         .       g.45206
 GAACTTCTGCAGACTCCAAATTTTCGAATTACCGTGGTTGATGATGCAGACACTGTTGAA       c.600
 E  L  L  Q  T  P  N  F  R  I  T  V  V  D  D  A  D  T  V  E         p.200

          .         | 06         .         .         .         .    g.57407
 CTCTGTGGTGCGCTTAAG | AACATCGTAGCTGTGGGAGCTGGGTTCTGCGACGGCCTCCGC    c.660
 L  C  G  A  L  K   | N  I  V  A  V  G  A  G  F  C  D  G  L  R      p.220

          .         .         .         .         .         .       g.57467
 TGTGGAGACAACACCAAAGCGGCCGTCATCCGCCTGGGACTCATGGAAATGATTGCTTTT       c.720
 C  G  D  N  T  K  A  A  V  I  R  L  G  L  M  E  M  I  A  F         p.240

          .         .         .         .         .         .       g.57527
 GCCAGGATCTTCTGCAAAGGCCAAGTGTCTACAGCCACCTTCCTAGAGAGCTGCGGGGTG       c.780
 A  R  I  F  C  K  G  Q  V  S  T  A  T  F  L  E  S  C  G  V         p.260

          .         .         .         .         .         .       g.57587
 GCCGACCTGATCACCACCTGTTACGGAGGGCGGAACCGCAGGGTGGCCGAGGCCTTCGCC       c.840
 A  D  L  I  T  T  C  Y  G  G  R  N  R  R  V  A  E  A  F  A         p.280

          .   | 07     .         .         .         .         .    g.58105
 AGAACTGGGAAG | ACCATTGAAGAGTTGGAGAAGGAGATGCTGAATGGGCAAAAGCTCCAA    c.900
 R  T  G  K   | T  I  E  E  L  E  K  E  M  L  N  G  Q  K  L  Q      p.300

          .         .         .         .         .          | 08    g.64304
 GGACCGCAGACTTCTGCTGAAGTGTACCGCATCCTCAAACAGAAGGGACTACTGGACAA | G    c.960
 G  P  Q  T  S  A  E  V  Y  R  I  L  K  Q  K  G  L  L  D  K  |      p.320

          .         .         .         .         .         .       g.64364
 TTTCCATTGTTTACTGCAGTGTATCAGATCTGCTACGAAAGCAGACCAGTTCAAGAGATG       c.1020
 F  P  L  F  T  A  V  Y  Q  I  C  Y  E  S  R  P  V  Q  E  M         p.340

          .         .         .                                     g.64400
 TTGTCTTGTCTTCAGAGCCATCCAGAGCATACATAA                               c.1056
 L  S  C  L  Q  S  H  P  E  H  T  X                                 p.351

          .         .         .         .         .         .       g.64460
 agtgaatcatgcaacgtgttgggggaagttctgcctttctgatcaatcttttgggttcac       c.*60

          .         .         .         .         .         .       g.64520
 gtggaaaccaggacttggcaacatgatgtttgactgtaatctcatcacggatatgtatga       c.*120

          .         .         .         .         .         .       g.64580
 atttttacaggttcgtttttgaattgtgagaggcagttcattagcaaagatgtactgggc       c.*180

          .         .         .         .         .         .       g.64640
 agtaactaaacacacatgcaaacatgtgaatggtggtttattcctcattctgtggatgtt       c.*240

          .         .         .         .         .         .       g.64700
 tctatgagccaaaatttgatgtctttttttcaaaattgcttatgaaatttccacacaatc       c.*300

          .         .         .         .         .         .       g.64760
 gtagcttataagattggaacgatctcagccaaatattttaggtgtaattcatatgtattt       c.*360

          .         .         .         .         .         .       g.64820
 gagtggaggattttttttctcatttttctagtgttaaattttaaccagcattaacatggt       c.*420

          .         .         .         .         .         .       g.64880
 agagtggaggagtgagtgtgttcaaagatcaacatatttaacttttaaacactatctcaa       c.*480

          .         .         .         .         .         .       g.64940
 agccagcataattaactactttgattgtgggctgacctttgtttttttaacaatcaggca       c.*540

          .         .         .         .         .         .       g.65000
 tttttaattagataatccactcatgtatttccccctcactgcagttgtctgcatttttag       c.*600

          .         .         .         .         .         .       g.65060
 cctcttttctcttcgttagttgtcagaatatgccttcgtcaaggctcagaggtaacaaga       c.*660

          .         .         .         .         .         .       g.65120
 cagaaaattcatctgggattttcctgctgtggctggcacattcttctgattaacagacac       c.*720

          .         .         .         .         .         .       g.65180
 ttgtatgatgctttaggctagttagtgcattttttagcaaacatttatcttaaacatcac       c.*780

          .         .         .         .         .         .       g.65240
 agatccactggggggtgcaaggggctactgttagtcctcttgttagatgcagtcactcct       c.*840

          .         .         .         .         .         .       g.65300
 cctggtcacctagtgagcagggacagagccaggagtcaagtgcagtgccaaggtgcatga       c.*900

          .         .         .         .         .         .       g.65360
 ccctctgagaagtcactgggctgatttgacctccgactcattggttgtgcaaatgccatg       c.*960

          .         .         .         .         .         .       g.65420
 tgcagcctttcctgaggccataggagggcttcctgcagctgagatctatgcaggccatcc       c.*1020

          .         .         .         .         .         .       g.65480
 tctcaacaagtgccactccaagggcggtcctcggtgcagcagcatcagcttcacttgtgg       c.*1080

          .         .         .         .         .         .       g.65540
 gggggtgggggaaggggcggtctcagaaatgcaggttcccaggtcccaccctggacttct       c.*1140

          .         .         .         .         .         .       g.65600
 gaaggggtgtggcatctgtgtttctgatgcttactacaatatgtgaaccactactttaga       c.*1200

          .         .         .         .         .         .       g.65660
 aaatctgctttaacttggtattcctctaattgtgttccctaggaaatgactgtcccaaga       c.*1260

          .         .         .         .         .         .       g.65720
 gccagtgattattccaggtgttccctggaaaggtcaagtgagtctgggaaacactatgtc       c.*1320

          .         .         .         .         .         .       g.65780
 tgtacacctcttgaaggtgtcgaatgtatgtttatacatcagtggaacccatttttctag       c.*1380

          .         .         .         .         .         .       g.65840
 cctagcaagtcccaaacacattacactgaagagattttggtgaggaaacttgctggagtt       c.*1440

          .         .         .         .         .         .       g.65900
 ttcagggaacactgttctaggcttaggtgaccttaggatcactcaagtagacccttcact       c.*1500

          .         .         .         .         .         .       g.65960
 ccctgcgagaaattaggatgaataactacctgtggcattgttggttctgaacttttacag       c.*1560

          .         .         .         .         .         .       g.66020
 ttcaggcctgctgtgaatctttgatgaagctttaaggtgacactgttgtacaagatgtca       c.*1620

          .         .         .         .         .         .       g.66080
 gctttgctgaaacgcacattacctggaataagtgctttaattgtagaattagaatgggat       c.*1680

          .         .         .         .         .         .       g.66140
 ttactgtactgttttaaatgagattggcttcagaatccattacagttaccttacatagca       c.*1740

          .         .         .         .         .         .       g.66200
 cttgatacgtgttaaatgaacatatgaatgtaatttatatattcctagaatttaagttac       c.*1800

          .         .         .         .         .         .       g.66260
 tttgtgagatttgggcctgtccctcaatgccagtttaggatttctttttttctatacctt       c.*1860

          .         .         .         .         .         .       g.66320
 gaaatgattataaaatagattttcatgggaattttaaaaactctatccaaaacatttttg       c.*1920

          .         .         .         .         .         .       g.66380
 gagcattttaaagccccatacacagaagtatacgaaagcacacaaaacactccaagtttc       c.*1980

          .         .         .         .         .         .       g.66440
 agcagttttagcgccaccattaacccactttgcttgtctcatgaaaaatctttgttaaag       c.*2040

          .         .         .         .         .         .       g.66500
 tttgtacacaggtaacaaaaagttactttaaaagatatataaagggctgtaagctaattg       c.*2100

          .         .         .         .         .         .       g.66560
 tggtgtctagtaagtagcataatgagatgtgaggagttggaactttgcgtgttttgcgta       c.*2160

          .         .         .         .         .         .       g.66620
 ttttcatctgcattcagcttcttactctgggtttgtactcgagtgttatttctttacaaa       c.*2220

          .         .         .         .         .         .       g.66680
 tgcccttgtaattaccactctgaagtctgctgactgtgtctcttgaacatacttaggata       c.*2280

          .         .         .         .         .         .       g.66740
 ttctgcacattatggaaaaaggtaaattttagaagtttctgctctactaactgtagatat       c.*2340

          .         .         .         .         .         .       g.66800
 ttatgactctgcgagttatctatttttataaccacctgtggtccattgttcattttaatt       c.*2400

          .         .         .         .         .         .       g.66860
 cacatttcttatgaagtatggtaacagggagggagacacctagattagcagctcaatttg       c.*2460

          .         .         .         .         .         .       g.66920
 tactacttcagccaatctgtgaatgtaaaaactacactgttgccttgctaggatccaccc       c.*2520

          .         .         .         .         .         .       g.66980
 tcctataatatggaacaaatatctgaatgaaatccaccctaggagacggagtcaaactaa       c.*2580

          .         .         .         .         .         .       g.67040
 acttgtggtttttcatttaacttttgactacagcatggccccatggcatccacaccaaga       c.*2640

          .         .         .         .         .         .       g.67100
 gggtgttgtgatgaggtgccggtgtgcaaagggaactttagtttttccactggttcttat       c.*2700

          .         .         .         .         .         .       g.67160
 ctgctagccttttacatacatgtgtactatatttgtttatagactgtaggtggatatata       c.*2760

          .         .         .         .                           g.67205
 atttaaaagcttgatttaataaacatttaaccccctaaacttgca                      c.*2805

 (downstream sequence)

Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The Glycerol-3-phosphate dehydrogenase 1-like protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.