IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) (IBA57) - coding DNA reference sequence

(used for variant description)

(last modified December 17, 2022)
This file was created to facilitate the description of sequence variants on transcript NM_001010867.2 in the IBA57 gene based on a coding DNA reference sequence following the HGVS recommendations.
The sequence was taken from NC_000001.10, covering IBA57 transcript NM_001010867.2.
Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
                                         .         .                g.5029
                                ctccctccggcggccaccgccaggggccg       c.-61

 .         .         .         .         .         .                g.5089
 ctgtggcacccgcccctcccgcttccttgggcccttcccgctgccccactcttgtccaag       c.-1

          .         .         .         .         .         .       g.5149
 ATGGCGACCGCGGCGCTGCTTCGAGGCGCCACTCCGGGGCGCGGCGGCCCGGTCTGGCGC       c.60
 M  A  T  A  A  L  L  R  G  A  T  P  G  R  G  G  P  V  W  R         p.20

          .         .         .         .         .         .       g.5209
 TGGCGGCTGCGCGCGGCCCCAAGGTGCCGCCTGGCCCACAGCTCCTGCAGTCCTGGTGGC       c.120
 W  R  L  R  A  A  P  R  C  R  L  A  H  S  S  C  S  P  G  G         p.40

          .         .         .         .         .         .       g.5269
 GACCCAACGGCCGGAGCGGCCTGGGCCTGCTTCCGGCTGGACGGGCGCACCCTGCTGCGC       c.180
 D  P  T  A  G  A  A  W  A  C  F  R  L  D  G  R  T  L  L  R         p.60

          .         .         .         .         .         .       g.5329
 GTGCGTGGCCCCGACGCGGCGCCCTTCCTGCTAGGGCTGCTGACCAATGAACTGCCGCTT       c.240
 V  R  G  P  D  A  A  P  F  L  L  G  L  L  T  N  E  L  P  L         p.80

          .         .         .         .         .         .       g.5389
 CCGAGTCCTGCGGCCGCGGGGGCCCCGCCTGCTGCGCGCGCGGGCTACGCCCACTTCCTG       c.300
 P  S  P  A  A  A  G  A  P  P  A  A  R  A  G  Y  A  H  F  L         p.100

          .         .         .         .  | 02      .         .    g.13983
 AACGTGCAGGGCCGGACGCTCTATGACGTCATCTTGTACGG | GCTCCAGGAACACTCGGAG    c.360
 N  V  Q  G  R  T  L  Y  D  V  I  L  Y  G  |  L  Q  E  H  S  E      p.120

          .         .         .         .         .         .       g.14043
 GTGTCTGGCTTCCTTCTGGAGTGTGACAGCTCGGTGCAGGGCGCGCTGCAGAAGCACCTC       c.420
 V  S  G  F  L  L  E  C  D  S  S  V  Q  G  A  L  Q  K  H  L         p.140

          .         .         .         .         .         .       g.14103
 GCGCTATACAGGATCCGGCGGAAGGTCACGGTGGAGCCGCACCCGGAGCTGCGAGTGTGG       c.480
 A  L  Y  R  I  R  R  K  V  T  V  E  P  H  P  E  L  R  V  W         p.160

          .         .         .         .         .         .       g.14163
 GCGGTGTTGCCCAGTTCCCCTGAGGCCTGCGGGGCTGCATCGCTGCAGGAGAGGGCAGGG       c.540
 A  V  L  P  S  S  P  E  A  C  G  A  A  S  L  Q  E  R  A  G         p.180

          .         .         .         .         .         .       g.14223
 GCTGCCGCCATCCTCATCCGCGACCCGCGAACAGCACGCATGGGGTGGCGGCTCCTCACC       c.600
 A  A  A  I  L  I  R  D  P  R  T  A  R  M  G  W  R  L  L  T         p.200

          .         .         .         .         .         .       g.14283
 CAGGATGAAGGCCCAGCCCTGGTGCCCGGGGGCCGGCTCGGGGACTTGTGGGATTATCAC       c.660
 Q  D  E  G  P  A  L  V  P  G  G  R  L  G  D  L  W  D  Y  H         p.220

          .          | 03        .         .         .         .    g.14435
 CAGCACCGATACCTGCAAG | GCGTTCCTGAGGGGGTCCGAGACTTGCCTCCTGGGGTGGCC    c.720
 Q  H  R  Y  L  Q  G |   V  P  E  G  V  R  D  L  P  P  G  V  A      p.240

          .         .         .         .         .         .       g.14495
 CTGCCCCTGGAGTCCAACCTGGCCTTCATGAACGGCGTGAGCTTCACCAAAGGCTGCTAC       c.780
 L  P  L  E  S  N  L  A  F  M  N  G  V  S  F  T  K  G  C  Y         p.260

          .         .         .         .         .         .       g.14555
 ATTGGCCAGGAGCTGACGGCCCGCACCCACCACATGGGCGTCATCCGCAAGCGCCTCTTC       c.840
 I  G  Q  E  L  T  A  R  T  H  H  M  G  V  I  R  K  R  L  F         p.280

          .         .         .         .         .         .       g.14615
 CCTGTCCGGTTCTTGGACCCCCTTCCCACCAGTGGCATCACCCCTGGTGCCACGGTGCTG       c.900
 P  V  R  F  L  D  P  L  P  T  S  G  I  T  P  G  A  T  V  L         p.300

          .         .         .         .         .         .       g.14675
 ACTGCCTCAGGACAGACTGTGGGCAAGTTCAGGGCTGGCCAGGGCAACGTGGGGCTGGCC       c.960
 T  A  S  G  Q  T  V  G  K  F  R  A  G  Q  G  N  V  G  L  A         p.320

          .         .         .         .         .         .       g.14735
 CTGCTGTGGTCAGAGAAGATCAAGGGTCCTCTGCACATCAGAGCCTCTGAGGGTGCCCAG       c.1020
 L  L  W  S  E  K  I  K  G  P  L  H  I  R  A  S  E  G  A  Q         p.340

          .         .         .         .         .                 g.14786
 GTGGCCTTAGCCGCATCTGTGCCAGACTGGTGGCCTACAGTCTCCAAGTAG                c.1071
 V  A  L  A  A  S  V  P  D  W  W  P  T  V  S  K  X                  p.356

          .         .         .         .         .         .       g.14846
 tccgaagccttggctggcgcaggctgatggggaggctggggcctggggcctttggcctct       c.*60

          .         .         .         .         .         .       g.14906
 gtccagggtcttcccgtcccatctgtctgctgcgcctactgggtgggagccctggtttcc       c.*120

          .         .         .         .         .         .       g.14966
 atctgggaaagtcccccttgtaggtgccctgcctggccccacccatgctcaggggcccca       c.*180

          .         .         .         .         .         .       g.15026
 ggcacgtgggttgttttctccctggacttcctgtggccccagaggagcccaccgtgtgag       c.*240

          .         .         .         .         .         .       g.15086
 tgctgggctccagatggcgccgggtcccaatcgtggctccacacagggttgtctgggagg       c.*300

          .         .         .         .         .         .       g.15146
 acgggacggtgtctctggccagcactggcagcttccgggccttgtaccccactctgcctg       c.*360

          .         .         .         .         .         .       g.15206
 gcatgagcctcatggggggttggtccctgtgcctggaagcggggtggtgtccagggtctg       c.*420

          .         .         .         .         .         .       g.15266
 caggctggggctcgggctttgggagttgtttcactgtgcttgcttccagcatgtctcagg       c.*480

          .         .         .         .         .         .       g.15326
 gtggggctatgcgtggtctagaggggtctggggcattggatcaggtggcatgtgggtgtc       c.*540

          .         .         .         .         .         .       g.15386
 tacacatcgagaagcacacagggatgagccactaggtatcccatgctggaggcttgtgga       c.*600

          .         .         .         .         .         .       g.15446
 aggctgtgcccatctcccatgtttccccacctctgttcctcctcagagccctccaggagc       c.*660

          .         .         .         .         .         .       g.15506
 gtggggtgggggccagcgcagggctcaggagccagcagggcagagttctgcctgtgtgtg       c.*720

          .         .         .         .         .         .       g.15566
 ctgggttttggcatagcctgtgtttgcagtgagagtgacttgctgtcagtcacggggcac       c.*780

          .         .         .         .         .         .       g.15626
 agcctcctgttcacccactggcttcccccttcccactgaagtgtgagctctatgtttcag       c.*840

          .         .         .         .         .         .       g.15686
 ggcatctattaaagagtgagccacaggcagccccttgggagctctggtttcatttggggg       c.*900

          .         .         .         .         .         .       g.15746
 agagggaggtgggggcttagtttttgtgatctggctgactggaccccgggaacagcgctc       c.*960

          .         .         .         .         .         .       g.15806
 ctttgagaacgcccagacctaccagatgaagcacttggcatggctgcaggccagcagggg       c.*1020

          .         .         .         .         .         .       g.15866
 aggcctcagaggcccaggctgggcacgtgggtgccgagtctgcaaaggacagccccatgg       c.*1080

          .         .         .         .         .         .       g.15926
 ctgtgagctgtcggctgcagggcgcagggcctggggggcaggcgtttgggccaccaagct       c.*1140

          .         .         .         .         .         .       g.15986
 ggacgttagggtggccacagagggccaagcaggcagggagcctgtgccgccatcctgggg       c.*1200

          .         .         .         .         .         .       g.16046
 ggccacaggtgctctctagaaatctgcagccatggcggttttggggtcaggggtctaaag       c.*1260

          .         .         .         .         .         .       g.16106
 gcagctctgagctgcagtgtagtttgtgatcacccaggaggagggtgtagagcggatgga       c.*1320

          .         .         .         .         .         .       g.16166
 cgggaggaagcggctgcagctggagggaagagaggggccgtccagcctcacccgctgcag       c.*1380

          .         .         .         .         .         .       g.16226
 tcagctctcctatgggcaaggaaacagctaggtggccctgacccctgcggtcctgagagc       c.*1440

          .         .         .         .         .         .       g.16286
 cggtggccttcagcccctcttggacaggtcatggtctggaagcgcccagcgcaggatgga       c.*1500

          .         .         .         .         .         .       g.16346
 ttccagaccagcatccctgcaaccttttcagccccactggctgctgctttaaactggcat       c.*1560

          .         .         .         .         .         .       g.16406
 ggagacatttgatcagcttcccagccagttttctctccagctcagccaggagtgggtgcc       c.*1620

          .         .         .         .         .         .       g.16466
 tgtggcctgtgtcaccaagagctggtgtctcctgcatgaggggcatgcacccctggaatg       c.*1680

          .         .         .         .         .         .       g.16526
 agggtctgtgcctcgagctcaaagtgtcccggctctgtcatctgcctgaagttgcctggc       c.*1740

          .         .         .         .         .         .       g.16586
 ttttccagtggggcctccttgagtgctgcagcatctgggagcatcctagcctgtcccgtg       c.*1800

          .         .         .         .         .         .       g.16646
 ggtgtggctgggtgagggctaggaggtgagccaggaaggaagcactccactccagagtga       c.*1860

          .         .         .         .         .         .       g.16706
 ggtgccgcctgagccatcctgtgccccctcagtgtcttcaggtctctgcaggtgtcagga       c.*1920

          .         .         .         .         .         .       g.16766
 tctcaaaatacttggttcagatcaaacacatttcgtgttcttctgtgtcctttttttttt       c.*1980

          .         .         .         .         .         .       g.16826
 ttttttttttttttgagatggagtcttgctctgttggccaggctggagctcagtggcaca       c.*2040

          .         .         .         .         .         .       g.16886
 atctctgctcactgcaacctctgcctcccaggttccagtgattttcctgcctcagcctcc       c.*2100

          .         .         .         .         .         .       g.16946
 tgggtagctgggactacaggcacatgccccatgcccggctaatttttgtatttttagtag       c.*2160

          .         .         .         .         .         .       g.17006
 agatggggttttaccatgttggccaggatggtctcaattacaggcatgagccactgtgcc       c.*2220

          .         .         .         .         .         .       g.17066
 cagcctcttctgtgtctttaaaaaggaaagtgtcagtcaacaaaagagcccctctgtcat       c.*2280

          .         .         .         .         .         .       g.17126
 acaaaccaaatcagttttcaccaaaatgtccttagtcctctcagaaaggcctggccttta       c.*2340

          .         .         .         .         .         .       g.17186
 ggaccttggaagcaggccctaaagcgcatcggcagggtcagagctttgtgttcaggaaca       c.*2400

          .         .         .         .         .         .       g.17246
 ctgggatctgctgagagctggtgtagccgctccaaaactgcacactgcttttcctgtctg       c.*2460

          .         .         .         .         .         .       g.17306
 ctttagtttgtgttgtaaaaacataggaagttcgtgtgtgtgtgtgtgtgtgtgaattca       c.*2520

          .         .         .         .         .         .       g.17366
 aggcataaggtgcagttgtgttatgtgggtatagtgcatggtggtgcagtctgggcttct       c.*2580

          .         .         .         .         .         .       g.17426
 taccctcacacctcctgcctcccctcgttagagtcccccacatccgccttccactttctg       c.*2640

          .         .         .         .         .         .       g.17486
 agcccacattgcctgttgggcagctcctggttatgaggcaggacgtgtggtgtttgactg       c.*2700

          .         .         .         .         .         .       g.17546
 tctgtttctgagctgttttacttaacacagtgtatatggtgcatctttaggaaagcatgc       c.*2760

          .         .         .         .         .         .       g.17606
 ttgtattttcctttcaaagccagatatgggcgggtgtggtggctcatgcctgtgatccca       c.*2820

          .         .         .         .         .         .       g.17666
 gcactttgggaggccgaggcaggaggattgcttgagcccaggagtttgagagcagcctgg       c.*2880

          .         .         .         .         .         .       g.17726
 gcaacatatcaagactctgtctcttaaaaaaaaaaaaattagccaggcatggtggtccac       c.*2940

          .         .         .         .         .         .       g.17786
 acctgtggtcccacctattcgggaggctgaagtgcgaggatcacttgagcccaggaggtt       c.*3000

          .         .         .         .         .         .       g.17846
 gaggctgcagtgagctgtgattgtgccactgcactccagcctgggcaacagagcaagacc       c.*3060

          .         .         .         .         .         .       g.17906
 ctgtcttaaaacaaagaaagaataaaaaagaagagaagttgcagttggtagtatttccag       c.*3120

          .         .         .         .         .         .       g.17966
 agcccggcagacagtgtagaaactgtgagaaacccacctccaaatcaggccttagataga       c.*3180

          .         .         .         .         .         .       g.18026
 aaacatcctaagaagtatacgttcattgtaaaatcattatcatcatcatcttctaatccc       c.*3240

          .         .         .         .         .         .       g.18086
 caaggagacaagctccctgttctgtgttcttgtatgaggcggtcagtcaagcgcagcccg       c.*3300

          .         .         .         .         .         .       g.18146
 agaggagaggcaggagcctgggagagcctctgctagacctttcctggcacttccccagga       c.*3360

          .         .         .         .         .         .       g.18206
 aaggcaaggcagggcagatgtgcggctggccagctggagtgatttccatgggctccaagc       c.*3420

          .         .         .         .         .         .       g.18266
 tgtaggagtggtccctggctgccagagtgctctggccagatagaggtgggctctggactg       c.*3480

          .         .         .         .         .         .       g.18326
 gtgaggctgcattgcggaggcgcgcacacccagctgggcccttatctgtaaggactggct       c.*3540

          .         .         .         .         .         .       g.18386
 ggcctgggaggggcagtctcccagccagaaggtggaatttttttttttttttgagatacc       c.*3600

          .         .         .         .         .         .       g.18446
 aaaacatcctaaggtacaggaaagaaattgtcaacacacacacacagtaccataaacaag       c.*3660

          .         .         .         .         .         .       g.18506
 gcccagcagaaaggcagacagaagcacacacaccaatgttctgatcttagagtaagcaga       c.*3720

          .         .         .         .         .         .       g.18566
 cacatcacatggaatgaggatgtttaatatatttaaagaaaacaatttatgcacaggaag       c.*3780

          .         .         .         .         .         .       g.18626
 caagagactataaaaatgaccaagcagattttaaaaagagaacttgttgaaataaaaata       c.*3840

          .         .         .         .         .         .       g.18686
 aaatactctaaaaaatattccatgatgtgtttcctgaagaatcgggaactgtttgaagaa       c.*3900

          .         .         .         .         .         .       g.18746
 atgacccaaagtgcagcacagaaagacagagctggaaaatatgagatgggatgagacaag       c.*3960

          .         .         .         .         .         .       g.18806
 aagatggagagtttagtatgacatccgcaatttacgagtaattccagaaggaggggaaag       c.*4020

          .         .         .         .         .         .       g.18866
 agaatatggggtggaggcaagtattcagagaaatacggctgagaactttcccaaaccaac       c.*4080

          .         .         .         .         .         .       g.18926
 aggagcccctgctccttaggttcaggaaccagcagctcccaagcagcatagttaaaaagc       c.*4140

          .         .         .         .         .         .       g.18986
 tctacccaaacagtcacgtcttggtgaaagtacagaatctcatgacaaagagatcttaag       c.*4200

          .         .         .         .         .         .       g.19046
 gcagaaaagaaagagattatctggaaagaagaaaataagtagttgattaaaagcaacagt       c.*4260

          .         .         .         .         .         .       g.19106
 ggaagccagaaagatagtaaataatatcttcaaagtcctgggagaaaatagtgatagcct       c.*4320

          .         .         .         .         .         .       g.19166
 agaattgtgtacccagaaaatccgtctttcaagaatgaggggccaggcgcagtggctcac       c.*4380

          .         .         .         .         .         .       g.19226
 gtctgtattcccagcactttgggaggccaaggcaggtggatcacctgaggtcaggagttc       c.*4440

          .         .         .         .         .         .       g.19286
 aagaccagcctgatcaacatggtgaaaccctgtctctactaaaaatataaaaattagctg       c.*4500

          .         .         .         .         .         .       g.19346
 ggtgtggtggcatattcctgtaatcccagctactcgggaggctgaggcaggagaatcact       c.*4560

          .         .         .         .         .         .       g.19406
 tgaacccaggaggcagaggttgcagtgagccaagattgtgccattgcactccagcctggg       c.*4620

          .         .         .         .         .         .       g.19466
 caatagaatgagactctgtctcaaaaaaaaaaaaaaaaaaaaaaaaaaaaagagggctaa       c.*4680

          .         .         .         .         .         .       g.19526
 acgcattttcataccacgaaactgccctcactccggagtttgctgccagcagagcctaga       c.*4740

          .         .         .         .         .         .       g.19586
 gcgtctaaggcatgtctgggcttctggcgagggatcctgtggggaagctggagatggaag       c.*4800

          .         .         .         .         .         .       g.19646
 aaggagtgaataggcaggaaggtggatttgtgggcatgtctaaaacaccacatctagaag       c.*4860

          .         .         .         .         .         .       g.19706
 cttctacttagaatgcctacttttggagtttataaaaaagatgccacatgttgagttggg       c.*4920

          .         .         .         .         .         .       g.19766
 agagaggtgcccaaacctacagtgttctaaagtccccctactggtcggaaggagggcacg       c.*4980

          .         .         .         .         .         .       g.19826
 gacactgacttcagcatctgttacaaggcttatcagagttttcagataatctctaaaaga       c.*5040

          .         .         .         .         .         .       g.19886
 atggaaatatatcttccaaactatagagggaagaccatggaatttaaaagccagtccttc       c.*5100

          .         .         .         .         .         .       g.19946
 aaggagaaatgaacaaactcaaaatcgtagttgggagtgttttttttttttttgagacag       c.*5160

          .         .         .         .         .         .       g.20006
 agtctcactcttgcccaggctggagtggagtggcataaacacagctcactacagcctcaa       c.*5220

          .         .         .         .         .         .       g.20066
 ccttctgggctcagatgattctcctgcctcagcctcctgagtagcaggaactacaggtgt       c.*5280

          .         .         .         .         .         .       g.20126
 gagtcatcacactcagctaattttttttttttttttttactttttgtagagatggggttc       c.*5340

          .         .         .         .         .         .       g.20186
 tcactgcattgcccaggctggtcttgaatttctgggctcaggtgatcttcccacctcagc       c.*5400

          .         .         .         .         .         .       g.20246
 ctcctgagtagctgggaccacaggtgcatgctaatttttaaaattttttgtttttaaatg       c.*5460

          .         .         .         .         .         .       g.20306
 ctggtcttcaactcttgtccccaagtagctgggattggggcatgaggcactgtgctaact       c.*5520

          .         .         .         .         .         .       g.20366
 tcatgttgaaattgaattgccattctaacagtgttaagagatggggcctgtaagaggtga       c.*5580

          .         .         .         .         .         .       g.20426
 ttaggctgtgagggctccactctccaagggcggagttaatgttatgaaagggtaagtcca       c.*5640

          .         .         .         .         .         .       g.20486
 gcccgcttgtgcctctcttgccctccagtgttcaaagcaccatcttggaggtggaattcc       c.*5700

          .         .         .         .         .         .       g.20546
 caagtcggccagttcctggatcttggactgtccggtctccagaaccgtgagccaataaac       c.*5760

          .         .         .         .         .         .       g.20606
 ctctgttccttgtaaatgagtcagcctcaggtattctcttgtagcagcacaaatggaggc       c.*5820

          .         .         .         .         .         .       g.20666
 agacacttccttcaccaatctcatgggaggcccactcctgtgagctgcctctagttcccc       c.*5880

          .         .         .         .         .         .       g.20726
 aggccacagactccatcagggctcacctggagccgtccctgtctcacctggaagctctcc       c.*5940

          .         .         .         .         .         .       g.20786
 cactcctctggccagcctgggcatctccacccaatatgagtgatggcgactgattccctt       c.*6000

          .         .         .         .         .         .       g.20846
 actttagcaagctgggaataaggaatgtttgcctgttcttattcaggggtctctgcatct       c.*6060

          .         .         .         .         .         .       g.20906
 ccacacttgcacaggttgtgtgtacatacattttcctgtctttctggtaagcccctgggg       c.*6120

          .         .         .         .         .         .       g.20966
 tggagctctgggccacagggcaggaaaactcagtgttgctaggaactgccagacattttc       c.*6180

          .         .         .         .         .         .       g.21026
 ccggagtgagtgcagcatttacattcccaccagaagtgtgccaggttcttgtcatactgc       c.*6240

          .         .         .         .         .         .       g.21086
 gtcctcgccagcgcttggtgctgtcagtcttcttagtttccatttagagattcagtgttt       c.*6300

          .         .         .         .         .         .       g.21146
 aaattttgaacgtcttgggtgaacaccttggtttgagaaaagtaagaaaaagggtctgtc       c.*6360

          .         .         .         .         .         .       g.21206
 tggctatgggccatggagacccagggcagtgctccacgtgccaaccctggggcagggagc       c.*6420

          .         .         .         .         .         .       g.21266
 ccaagctaggactgtgactgtctgggctgtgggcatctgaccatctccagtgtccccgtc       c.*6480

          .         .         .         .         .         .       g.21326
 tttgatttccctggcgatggtgctagcttagtttgtgcgcatcggcatttgtgggagaaa       c.*6540

          .         .         .         .         .         .       g.21386
 tgaaggattaatacattttgttttatgtcagactctctcagtgagaagttctcagggaca       c.*6600

          .         .         .         .         .         .       g.21446
 ataatagcagggggtcctgctgaagaaaaactgggagatggctgagctctggtccatctt       c.*6660

          .         .         .         .         .         .       g.21506
 tcattgattcattcatttcttcattcattcaaccatgtattgaatgcttatagccaatga       c.*6720

          .         .                                               g.21530
 aaataaagtacacagtatatttta                                           c.*6744

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.