monoacylglycerol O-acyltransferase 3 (MOGAT3) - coding DNA reference sequence

(used for variant description)

(last modified February 13, 2015)

This file was created to facilitate the description of sequence variants on transcript NM_178176.2 in the MOGAT3 gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NC_000007.13, covering MOGAT3 transcript NM_178176.2.

Please note that introns are available by clicking on the exon numbers above the sequence.

 (upstream sequence)
                     .         .         .         .                g.5047
              cactcacacacctacggacacacgctactctgggaggtgatttgcga       c.-121

 .         .         .         .         .         .                g.5107
 cttagccaggcccccaaagctgggctcctgtagggagaaagtctgcccaggtccacatcc       c.-61

 .         .         .         .         .         .                g.5167
 aagccttcatcgtttgtcctccgggttctgggatcctgctggaagaggggagcttctgca       c.-1

          .         .         .         .         .         .       g.5227
 ATGGGAGTTGCCACAACCCTGCAGCCCCCAACCACTTCCAAAACCTTGCAGAAGCAGCAT       c.60
 M  G  V  A  T  T  L  Q  P  P  T  T  S  K  T  L  Q  K  Q  H         p.20

          .         .         .         .          | 02        .    g.5517
 CTAGAAGCAGTGGGCGCCTACCAATATGTGCTCACTTTCCTCTTCATGG | GCCCTTTCTTC    c.120
 L  E  A  V  G  A  Y  Q  Y  V  L  T  F  L  F  M  G |   P  F  F      p.40

          .         .         .         .         .         .       g.5577
 TCCCTTCTTGTCTTTGTCCTCCTCTTCACGTCACTCTGGCCCTTCTCTGTTTTTTACTTG       c.180
 S  L  L  V  F  V  L  L  F  T  S  L  W  P  F  S  V  F  Y  L         p.60

          .         .         .        | 03.         .         .    g.5740
 GTGTGGCTCTATGTGGACTGGGACACACCCAACCAAG | GTGGAAGGCGTTCGGAGTGGATA    c.240
 V  W  L  Y  V  D  W  D  T  P  N  Q  G |   G  R  R  S  E  W  I      p.80

          .         .         .         .         | 04         .    g.7203
 AGGAACCGGGCAATTTGGAGACAACTAAGGGATTATTATCCTGTCAAG | CTGGTGAAAACA    c.300
 R  N  R  A  I  W  R  Q  L  R  D  Y  Y  P  V  K   | L  V  K  T      p.100

          .         .         .         .         .         .       g.7263
 GCAGAGCTGCCCCCGGATCGGAACTACGTGCTGGGCGCCCACCCTCATGGGATCATGTGT       c.360
 A  E  L  P  P  D  R  N  Y  V  L  G  A  H  P  H  G  I  M  C         p.120

          .         .         .         .         .         .       g.7323
 ACAGGCTTCCTCTGTAATTTCTCCACCGAGAGCAATGGCTTCTCCCAGCTCTTCCCGGGG       c.420
 T  G  F  L  C  N  F  S  T  E  S  N  G  F  S  Q  L  F  P  G         p.140

          .         .         .         .         .         .       g.7383
 CTCCGGCCCTGGTTAGCCGTGCTGGCTGGCCTCTTCTACCTCCCGGTCTATCGCGACTAC       c.480
 L  R  P  W  L  A  V  L  A  G  L  F  Y  L  P  V  Y  R  D  Y         p.160

          .    | 05    .         .         .         .         .    g.7703
 ATCATGTCCTTTG | GACTCTGTCCGGTGAGCCGCCAGAGCCTGGACTTCATCCTGTCCCAG    c.540
 I  M  S  F  G |   L  C  P  V  S  R  Q  S  L  D  F  I  L  S  Q      p.180

          .         .         .         .         .         .       g.7763
 CCCCAGCTCGGGCAGGCCGTGGTCATCATGGTGGGGGGTGCGCACGAGGCCCTGTATTCA       c.600
 P  Q  L  G  Q  A  V  V  I  M  V  G  G  A  H  E  A  L  Y  S         p.200

          .         .         .         .         .         .       g.7823
 GTCCCCGGGGAGCACTGCCTTACGCTCCAGAAGCGCAAAGGCTTCGTGCGCCTGGCGCTG       c.660
 V  P  G  E  H  C  L  T  L  Q  K  R  K  G  F  V  R  L  A  L         p.220

          | 06         .         .         .         .         .    g.9684
 AGGCACGG | GGCGTCCCTGGTGCCCGTGTACTCCTTTGGGGAGAATGACATCTTTAGACTT    c.720
 R  H  G  |  A  S  L  V  P  V  Y  S  F  G  E  N  D  I  F  R  L      p.240

          .         .         .         .         .         .       g.9744
 AAGGCTTTTGCCACAGGCTCCTGGCAGCATTGGTGCCAGCTCACCTTCAAGAAGCTCATG       c.780
 K  A  F  A  T  G  S  W  Q  H  W  C  Q  L  T  F  K  K  L  M         p.260

          .         .         .         .         .         .       g.9804
 GGCTTCTCTCCTTGCATCTTCTGGGGTCGCGGTCTCTTCTCAGCCACCTCCTGGGGCCTG       c.840
 G  F  S  P  C  I  F  W  G  R  G  L  F  S  A  T  S  W  G  L         p.280

          .         .         .  | 07      .         .         .    g.9950
 CTGCCCTTTGCTGTGCCCATCACCACTGTGG | TGGGCCGCCCCATCCCCGTCCCCCAGCGC    c.900
 L  P  F  A  V  P  I  T  T  V  V |   G  R  P  I  P  V  P  Q  R      p.300

          .         .         .         .         .         .       g.10010
 CTCCACCCCACCGAGGAGGAAGTCAATCACTATCACGCCCTCTACATGACGGCCCTGGAG       c.960
 L  H  P  T  E  E  E  V  N  H  Y  H  A  L  Y  M  T  A  L  E         p.320

          .         .         .         .         .         .       g.10070
 CAGCTCTTCGAGGAGCACAAGGAAAGCTGTGGGGTCCCCGCTTCCACCTGCCTCACCTTC       c.1020
 Q  L  F  E  E  H  K  E  S  C  G  V  P  A  S  T  C  L  T  F         p.340

                                                                    g.10076
 ATCTAG                                                             c.1026
 I  X                                                               p.341

          .         .         .         .         .         .       g.10136
 gcctggccgcggcctttcgctgagcccctgagcccaaggcactgagacctccacccactg       c.*60

          .         .         .         .         .         .       g.10196
 tggactccatgcctccaataaaaggtagttctgggcccagcgcagtgcctcatgcctgta       c.*120

          .         .         .         .         .         .       g.10256
 atcccagcactttgggaggccaaggtgggaggatcgtttgagcccaggagttgaagacca       c.*180

          .         .         .                                     g.10293
 gcctgggcaacacagtgagacttcatttctacaaaaa                              c.*217

 (downstream sequence)

Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The Monoacylglycerol O-acyltransferase 3 protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.