nuclear receptor subfamily 2, group F, member 2 (NR2F2) - coding DNA reference sequence

(used for variant description)

(last modified May 30, 2014)
This file was created to facilitate the description of sequence variants on transcript NM_021005.3 in the NR2F2 gene based on a coding DNA reference sequence following the HGVS recommendations.
The sequence was taken from NC_000015.9, covering NR2F2 transcript NM_021005.3.
Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
                                         .         .                g.9978
                                     gccgtactgccttttttcccctct       c.-1201

 .         .         .         .         .         .                g.10038
 ttcattctttctctccgtctttttctcccccctctgcgcacgaaggatgtgcttctaggt       c.-1141

 .         .         .         .         .         .                g.10098
 ggtgatctgccctcctctctctcttttatcatttctcccccgccgccggcgagttgactc       c.-1081

 .         .         .         .         .         .                g.10158
 tttccctatgtgtgtgaggcggcggcggcagcagcagcagcagcggctccggcggcggca       c.-1021

 .         .         .         .         .         .                g.10218
 gcagcggcagcagcgacttcagcggcggcggcggcgctagacgcagcggctccgggcccg       c.-961

 .         .         .         .         .         .                g.10278
 acccggcggcttcggcggcggctccggcggcagcggcggcccgggcggcccgcagggaac       c.-901

 .         .         .         .         .         .                g.10338
 ggcgagcggcctccacccagcgactgcgggcggcggcggccggagagagcgaggcgcgcg       c.-841

 .         .         .         .         .         .                g.10398
 ccggacgcccggggcaggcggcggcggcggcggcccagcgccaggacgacgccgcgcagc       c.-781

 .         .         .         .         .         .                g.10458
 gcccgacgcggaccactttcatgctgattcccccggacccgggcagcgctccggccactc       c.-721

 .         .         .         .         .         .                g.10518
 cgcgggccgccggcctccgccccggcctgcctggctccctgggcgcgcccgcacccggcg       c.-661

 .         .         .         .         .         .                g.10578
 cctccgatctcctagtcctcctgatttcgatggctttcctgaatggctgactgtgggctg       c.-601

 .         .         .         .         .         .                g.10638
 ccctggacttggcccccggacagtcgcctctcctcctcctctacctcctccttcaccacc       c.-541

 .         .         .         .         .         .                g.10698
 acctcctcttcctcctcctcctcctcctcctcctccgccaactcctcggctgcacaccag       c.-481

 .         .         .         .         .         .                g.10758
 ctctaagagcgagagtgaacgagagagggagggagagagtgagagcgagcgagatctttg       c.-421

 .         .         .         .         .         .                g.10818
 gagagatttttttttttgcctcctacttctgtcttgaagccagacaatcgacttcagctc       c.-361

 .         .         .         .         .         .                g.10878
 tccctcccctccctctttctccacgttctgctcccactcgctctcctgtccccttcccct       c.-301

 .         .         .         .         .         .                g.10938
 cccctcccggcggaaagccccccgaaaccaacaaagctgagccgagagaaacaaacaaaa       c.-241

 .         .         .         .         .         .                g.10998
 caaacacaccgggccagacaagccatcgacaaaactttgcaaaagcaaaaacaaaaaagg       c.-181

 .         .         .         .         .         .                g.11058
 aaaaactaaccaacctcaaccaaccagcccccgagccacccggggcgccctcccgcgccc       c.-121

 .         .         .         .         .         .                g.11118
 tcttgcaccctcgcacacacaaaaggcggcgcgccggagcccgagacccggggagccgcc       c.-61

 .         .         .         .         .         .                g.11178
 gccgccccgccgccgcccgcagccaggggagcaggaagtccggacgcagcccccatagat       c.-1

          .         .         .         .         .         .       g.11238
 ATGGCAATGGTAGTCAGCACGTGGCGCGACCCCCAGGACGAGGTGCCCGGCTCACAGGGC       c.60
 M  A  M  V  V  S  T  W  R  D  P  Q  D  E  V  P  G  S  Q  G         p.20

          .         .         .         .         .         .       g.11298
 AGCCAGGCCTCGCAGGCGCCGCCCGTGCCCGGCCCGCCGCCCGGCGCCCCGCACACGCCA       c.120
 S  Q  A  S  Q  A  P  P  V  P  G  P  P  P  G  A  P  H  T  P         p.40

          .         .         .         .         .         .       g.11358
 CAGACGCCCGGCCAAGGGGGCCCAGCCAGCACGCCAGCCCAGACGGCGGCCGGTGGCCAG       c.180
 Q  T  P  G  Q  G  G  P  A  S  T  P  A  Q  T  A  A  G  G  Q         p.60

          .         .         .         .         .         .       g.11418
 GGCGGCCCTGGCGGCCCGGGTAGCGACAAGCAGCAGCAGCAGCAACACATCGAGTGCGTG       c.240
 G  G  P  G  G  P  G  S  D  K  Q  Q  Q  Q  Q  H  I  E  C  V         p.80

          .         .         .         .         .         .       g.11478
 GTGTGCGGAGACAAGTCGAGCGGCAAGCACTACGGCCAGTTCACGTGCGAGGGCTGCAAG       c.300
 V  C  G  D  K  S  S  G  K  H  Y  G  Q  F  T  C  E  G  C  K         p.100

          .         .         .         .         .         .       g.11538
 AGCTTCTTCAAGCGCAGCGTGCGGAGGAACCTGAGCTACACGTGCCGCGCCAACCGGAAC       c.360
 S  F  F  K  R  S  V  R  R  N  L  S  Y  T  C  R  A  N  R  N         p.120

          .         .         .         .         .         .       g.11598
 TGTCCCATCGACCAGCACCATCGCAACCAGTGCCAGTACTGCCGCCTCAAAAAGTGCCTC       c.420
 C  P  I  D  Q  H  H  R  N  Q  C  Q  Y  C  R  L  K  K  C  L         p.140

          .         .   | 02     .         .         .         .    g.13186
 AAAGTGGGCATGAGACGGGAAG | CGGTGCAGAGGGGCAGGATGCCGCCGACCCAGCCGACC    c.480
 K  V  G  M  R  R  E  A |   V  Q  R  G  R  M  P  P  T  Q  P  T      p.160

          .         .         .         .         .         .       g.13246
 CACGGGCAGTTCGCGCTGACCAACGGGGATCCCCTCAACTGCCACTCGTACCTGTCCGGA       c.540
 H  G  Q  F  A  L  T  N  G  D  P  L  N  C  H  S  Y  L  S  G         p.180

          .         .         .         .         .         .       g.13306
 TATATTTCCCTGCTGTTGCGCGCGGAGCCCTATCCCACGTCGCGCTTCGGCAGCCAATGC       c.600
 Y  I  S  L  L  L  R  A  E  P  Y  P  T  S  R  F  G  S  Q  C         p.200

          .         .         .         .         .         .       g.13366
 ATGCAGCCCAACAACATCATGGGTATCGAGAACATTTGCGAACTGGCCGCGAGGATGCTC       c.660
 M  Q  P  N  N  I  M  G  I  E  N  I  C  E  L  A  A  R  M  L         p.220

          .         .         .         .         .         .       g.13426
 TTCAGCGCCGTCGAGTGGGCCCGGAACATCCCCTTCTTCCCCGACCTGCAGATCACGGAC       c.720
 F  S  A  V  E  W  A  R  N  I  P  F  F  P  D  L  Q  I  T  D         p.240

          .         .         .         .         .         .       g.13486
 CAGGTGGCCCTGCTTCGCCTCACCTGGAGCGAGCTGTTTGTGTTGAATGCGGCGCAGTGC       c.780
 Q  V  A  L  L  R  L  T  W  S  E  L  F  V  L  N  A  A  Q  C         p.260

          .         .         .         .         .         .       g.13546
 TCCATGCCCCTCCACGTCGCCCCGCTCCTGGCCGCCGCCGGCCTGCATGCTTCGCCCATG       c.840
 S  M  P  L  H  V  A  P  L  L  A  A  A  G  L  H  A  S  P  M         p.280

          .         .         .         .         .         .       g.13606
 TCCGCCGACCGGGTGGTCGCCTTTATGGACCACATACGGATCTTCCAAGAGCAAGTGGAG       c.900
 S  A  D  R  V  V  A  F  M  D  H  I  R  I  F  Q  E  Q  V  E         p.300

          .         .         .         .         .         .       g.13666
 AAGCTCAAGGCGCTGCACGTTGACTCAGCCGAGTACAGCTGCCTCAAGGCCATAGTCCTG       c.960
 K  L  K  A  L  H  V  D  S  A  E  Y  S  C  L  K  A  I  V  L         p.320

          . | 03       .         .         .         .         .    g.16470
 TTCACCTCAG | ATGCCTGTGGTCTCTCTGATGTAGCCCATGTGGAAAGCTTGCAGGAAAAG    c.1020
 F  T  S  D |   A  C  G  L  S  D  V  A  H  V  E  S  L  Q  E  K      p.340

          .         .         .         .         .         .       g.16530
 TCTCAGTGTGCTTTGGAAGAATACGTTAGGAGCCAGTACCCCAACCAGCCGACGAGATTC       c.1080
 S  Q  C  A  L  E  E  Y  V  R  S  Q  Y  P  N  Q  P  T  R  F         p.360

          .         .         .         .         .         .       g.16590
 GGAAAGCTTTTGCTTCGCCTCCCTTCCCTCCGCACCGTCTCCTCCTCAGTCATAGAGCAA       c.1140
 G  K  L  L  L  R  L  P  S  L  R  T  V  S  S  S  V  I  E  Q         p.380

          .         .         .         .         .         .       g.16650
 TTGTTTTTCGTCCGTTTGGTAGGTAAAACCCCCATCGAAACCCTCATCCGGGATATGTTA       c.1200
 L  F  F  V  R  L  V  G  K  T  P  I  E  T  L  I  R  D  M  L         p.400

          .         .         .         .                           g.16695
 CTGTCCGGCAGCAGTTTTAACTGGCCGTATATGGCAATTCAATAA                      c.1245
 L  S  G  S  S  F  N  W  P  Y  M  A  I  Q  X                        p.414

          .         .         .         .         .         .       g.16755
 ataaataaaataagaagggggagtgaaacagagaaagaaaaggcaaaagactggtttgtt       c.*60

          .         .         .         .         .         .       g.16815
 tgcttaatttccttctgttaagaaaggatataaaaggatgttacaagtttgctaaaagaa       c.*120

          .         .         .         .         .         .       g.16875
 gagaggggaagaatttaatggactgtgaatttcaaaaaaaaaaaaaaagactgtcaaatg       c.*180

          .         .         .         .         .         .       g.16935
 aacttttacagaatgcattaaaaaaaaaaaaaaactcctgtgtcggtcagaacaacttgc       c.*240

          .         .         .         .         .         .       g.16995
 tacttatcatttttgtataaaaaggaaattagtctttttctttttttggtaaatttttga       c.*300

          .         .         .         .         .         .       g.17055
 aaaatattgctaaaagtgcatttaaggagattgggagacaattagcagaatggagaaagt       c.*360

          .         .         .         .         .         .       g.17115
 aagtcttttttttttccaaattattaattgtcctgtgtctatgtacctctagctgttctt       c.*420

          .         .         .         .         .         .       g.17175
 ttttgtacttttctggttccaaaccagtttattctgtggttctataataagttttgatat       c.*480

          .         .         .         .         .         .       g.17235
 aatcttggcttcttaaaaactgtgtatcattaaaatatatgttctgcaagaattaaaact       c.*540

          .         .         .         .         .         .       g.17295
 gagtccatgaaaataccataggaagacataaaactttaaaaggcaactcaaagatgatgg       c.*600

          .         .         .         .         .         .       g.17355
 aaacgcacttacaagtggtgaccaaaatttttaggtgaagtcgagcactctaattagaga       c.*660

          .         .         .         .         .         .       g.17415
 actggaggaaccacatataacacttaacttcccctaccctgcccctccccaaaagaaacc       c.*720

          .         .         .         .         .         .       g.17475
 atgacaaacctagcttttaaaaaatattttaagaaagagaatgaactgtggaatttattg       c.*780

          .         .         .         .         .         .       g.17535
 gcagccaaggaatgtgtccaagacacatgctgaggttttgaataaaaagtgaacttttgt       c.*840

          .         .         .         .         .         .       g.17595
 aatttgaattgggtcccgcttagttcttgaattgttatgaaaatcctatatctgtttgta       c.*900

          .         .         .         .         .         .       g.17655
 tatttgcaaaccctttgtattataattgttgatattttccctttttaaaaaataccattg       c.*960

          .         .         .         .         .         .       g.17715
 aaatcagcatgacaaaaataacactgttggcacttataggtaacgtgattgattcagtat       c.*1020

          .         .         .         .         .         .       g.17775
 cttagagtttacagtttgtgttttaaaaaaactgaaggttttttttttaagtgcaacatt       c.*1080

          .         .         .         .         .         .       g.17835
 tctgtatactgtaaaagttataataactgaactgtttggtcgagtctttgtgtgttatat       c.*1140

          .         .         .         .         .         .       g.17895
 tccaaggaaaattgaaagtattcagaaattaaaatattatttgatatctgaaacctggct       c.*1200

          .         .         .         .         .         .       g.17955
 gtccccactcactgtctttacatctagaagagcccctgtgagctctcgcttagctggccg       c.*1260

          .         .         .         .         .         .       g.18015
 ggcggggggtggtgggggggggcatttgtttactcccctcagtcagtttgttcaaaggtg       c.*1320

          .         .         .         .         .         .       g.18075
 gactactgtatttgcctgtttaatttgggtgtgtgtgtgttggggggggagctgaagtta       c.*1380

          .         .         .         .         .         .       g.18135
 atggtttatctatggtttaggaagtgccatactgatatagtaaaccacccccattcacct       c.*1440

          .         .         .         .         .         .       g.18195
 aatcctccttttaattaaaaatggattttccaggaaaaaaaaaaaggcccttatatttgt       c.*1500

          .         .         .         .         .         .       g.18255
 cacacttaagtgcctgcttagggaaggtattgtgaaaaagtattagaaatcttgagatca       c.*1560

          .         .         .         .         .         .       g.18315
 gtatctattttatgatcagaaaaaaatactcttttgtacatttctgacagttactcagaa       c.*1620

          .         .         .         .         .         .       g.18375
 gatcgttcaagcaagctaatcacagcattgtaactagaggacagttgtttgcagtgagtt       c.*1680

          .         .         .         .         .         .       g.18435
 tttccttaagtaggtacgattttttaaaatattctgtgattctactctagcgtggttgtt       c.*1740

          .         .         .         .         .         .       g.18495
 gagagagtttcaaattcagtgatacaggttctaagactgaaaggtctacttttaatgtat       c.*1800

          .         .         .         .         .         .       g.18555
 atatgataacttgcagttggtttccctctcccctccccccctttaccttcagtctgtgag       c.*1860

          .         .         .         .         .         .       g.18615
 agcatgaccacagggtcaagggaatcttttccattggagttatgtacataaaaacacatc       c.*1920

          .         .         .         .         .         .       g.18675
 gacattttgacatttcagattgtgtggctacaatctgtactgctcttgggatcctttgtc       c.*1980

          .         .         .         .         .         .       g.18735
 cttagaagccaaattaaggaagagaaagcaggacagagaaaaagaaagaaggaaggaggg       c.*2040

          .         .         .         .         .         .       g.18795
 aaactttacagggtgtgctgatttggaagtagtaactatttcttttggagtctttttttc       c.*2100

          .         .         .         .         .         .       g.18855
 atttttcctctttctcttttcctggtttggaggaagctcggtgctgggagcttgcaattt       c.*2160

          .         .         .         .         .         .       g.18915
 tgttcttattcaaggtttccaacccacccccccaccgccagtacttcatcatgttgtggt       c.*2220

          .         .         .         .         .         .       g.18975
 ttaattctaattggtgggggggggggaggactagtgagggaggtgaaagaacagggataa       c.*2280

          .         .         .         .         .         .       g.19035
 ttttgtaaagtgtattaaacgttaatattcagatccagtcaatacatgcagaccagtaaa       c.*2340

          .         .         .         .         .         .       g.19095
 atctgatttgtgcagagttctccatctgactctcacttatttctgtagatatatacatat       c.*2400

          .         .         .         .         .         .       g.19155
 ataaatacaagtatgttcttacggcacagtattgctgacctttagttcgaggttttgtcg       c.*2460

          .         .         .         .         .         .       g.19215
 gttgttgttgattttcttcctcttgcaagtgctatccatgtgagtgtgtgaagtttctct       c.*2520

          .         .         .         .         .         .       g.19275
 aataagtaaaacacaggcccttttccttgtttgttttgtgttagtttattgtaaacagcc       c.*2580

          .         .         .         .         .         .       g.19335
 atttgttgtaaattattattggcattaaattataatttatgattttcaaagcaaaagaca       c.*2640

                                                                    g.19336
 a                                                                  c.*2641

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The Nuclear receptor subfamily 2, group F, member 2 protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.