(used for variant description)
(last modified November 25, 2020)
This file was created to facilitate the description of sequence variants on transcript NM_002739.3 in the PRKCG gene based on a coding DNA reference sequence following the HGVS recommendations.
The sequence was taken from NG_009114.1, covering PRKCG transcript NM_002739.3.
(upstream sequence)
. . . . g.5042
cggagctggagctcccaccgccgccgcccgtgcctccggctg c.-241
. . . . . . g.5102
ccggcgcccctgcctttggctcttcctccccactcgcccgctccccctggcggagccggc c.-181
. . . . . . g.5162
gcgcccggggtgccgctccctgcctggcgcgctccgcacctggaggtgccttgcccctct c.-121
. . . . . . g.5222
cctgcccacctcggaatttccctgtggctcctttgatccttcgagtctccagctcctctc c.-61
. . . . . . g.5282
ccttccacctgtttcccccaagaaaggcaggatcctggtccctgctacgtttctggggcc c.-1
. . . . . . g.5342
ATGGCTGGTCTGGGCCCCGGCGTAGGCGATTCAGAGGGGGGACCCCGGCCCCTGTTTTGC c.60
M A G L G P G V G D S E G G P R P L F C p.20
. . . . . . g.5402
AGAAAGGGGGCCCTGAGGCAGAAGGTGGTCCACGAAGTCAAGAGCCACAAGTTCACCGCT c.120
R K G A L R Q K V V H E V K S H K F T A p.40
. . . . . | 02 . g.5960
CGCTTCTTCAAGCAGCCCACCTTCTGCAGCCACTGCACCGACTTCATCTG | GGGTATCGGA c.180
R F F K Q P T F C S H C T D F I W | G I G p.60
. . | 03 . . . . g.6986
AAGCAGGGCCTGCAATGTCAAG | TCTGCAGCTTTGTGGTTCATCGACGATGCCACGAATTT c.240
K Q G L Q C Q V | C S F V V H R R C H E F p.80
. . . . | 04 . . g.12440
GTGACCTTCGAGTGTCCAGGCGCTGGGAAGGGCCCCCAGACGGAC | GACCCCCGGAACAAA c.300
V T F E C P G A G K G P Q T D | D P R N K p.100
. . . . . . g.12500
CACAAGTTCCGCCTGCATAGCTACAGCAGCCCCACCTTCTGCGACCACTGTGGCTCCCTC c.360
H K F R L H S Y S S P T F C D H C G S L p.120
. . . | 05. . . g.12696
CTCTACGGGCTTGTGCACCAGGGCATGAAATGCTCCT | GCTGCGAGATGAACGTGCACCGG c.420
L Y G L V H Q G M K C S C | C E M N V H R p.140
. . . . . . g.12756
CGCTGTGTGCGTAGCGTGCCCTCCCTGTGCGGTGTGGACCACACCGAGCGCCGCGGGCGC c.480
R C V R S V P S L C G V D H T E R R G R p.160
. . . . | 06 . g.14472
CTGCAGCTGGAGATCCGGGCTCCCACAGCAGATGAGATCCACGTAACTG | TTGGCGAGGCC c.540
L Q L E I R A P T A D E I H V T V | G E A p.180
. . . . . . g.14532
CGTAACCTAATTCCTATGGACCCCAATGGTCTCTCTGATCCCTATGTGAAACTGAAGCTC c.600
R N L I P M D P N G L S D P Y V K L K L p.200
. . . . . . g.14592
ATCCCAGACCCTCGGAACCTGACGAAACAGAAGACCCGAACGGTGAAAGCCACGCTAAAC c.660
I P D P R N L T K Q K T R T V K A T L N p.220
. . | 07 . . . . g.15330
CCTGTGTGGAATGAGACCTTTGTGTT | CAACCTGAAGCCAGGGGATGTGGAGCGCCGGCTC c.720
P V W N E T F V F | N L K P G D V E R R L p.240
. . . . . . g.15390
AGCGTGGAGGTGTGGGACTGGGACCGGACCTCCCGCAACGACTTCATGGGGGCCATGTCC c.780
S V E V W D W D R T S R N D F M G A M S p.260
. . . . | 08 . . g.15794
TTTGGCGTCTCGGAGCTGCTCAAGGCGCCCGTGGATGGCTG | GTACAAGTTACTGAACCAG c.840
F G V S E L L K A P V D G W | Y K L L N Q p.280
. . . . . . g.15854
GAGGAGGGCGAGTATTACAATGTGCCGGTGGCCGATGCTGACAACTGCAGCCTCCTCCAG c.900
E E G E Y Y N V P V A D A D N C S L L Q p.300
| 09 . . | 10 . . g.20767
AAGTTTGAG | GCTTGTAACTACCCCCTGGAATTGTATGAG | CGGGTGCGGATGGGCCCCTCT c.960
K F E | A C N Y P L E L Y E | R V R M G P S p.320
. . . . . . g.20827
TCCTCTCCCATCCCCTCCCCTTCCCCTAGTCCCACCGACCCCAAGCGCTGCTTCTTCGGG c.1020
S S P I P S P S P S P T D P K R C F F G p.340
. . . . . . g.20887
GCGAGTCCAGGACGCCTGCACATCTCCGACTTCAGCTTCCTCATGGTTCTAGGAAAAGGC c.1080
A S P G R L H I S D F S F L M V L G K G p.360
. | 11 . . . . . g.21275
AGTTTTGGGAAG | GTGATGCTGGCCGAGCGCAGGGGCTCTGATGAGCTCTACGCCATCAAG c.1140
S F G K | V M L A E R R G S D E L Y A I K p.380
. . . . . . g.21335
ATCTTGAAAAAGGACGTGATCGTCCAGGACGACGATGTGGACTGCACGCTGGTGGAGAAA c.1200
I L K K D V I V Q D D D V D C T L V E K p.400
. . . . . . g.21395
CGTGTGCTGGCGCTGGGGGGCCGGGGTCCTGGCGGCCGGCCCCACTTCCTCACCCAGCTC c.1260
R V L A L G G R G P G G R P H F L T Q L p.420
. . | 12 . . . . g.23059
CACTCCACCTTCCAGACCCCG | GACCGCCTGTATTTCGTGATGGAGTACGTCACCGGGGGA c.1320
H S T F Q T P | D R L Y F V M E Y V T G G p.440
. . . . . | 13 . g.23213
GACTTGATGTACCACATTCAACAGCTGGGCAAGTTTAAGGAGCCCCATGCAGC | GTTCTAC c.1380
D L M Y H I Q Q L G K F K E P H A A | F Y p.460
. . . . . | 14 . g.23402
GCGGCAGAAATCGCTATCGGCCTCTTCTTCCTTCACAATCAGGGCATCATCTACAG | GGAC c.1440
A A E I A I G L F F L H N Q G I I Y R | D p.480
. . . . . . g.23462
CTGAAGCTGGACAATGTGATGCTGGATGCTGAGGGACACATCAAGATCACTGACTTTGGC c.1500
L K L D N V M L D A E G H I K I T D F G p.500
. . . . . . g.23522
ATGTGTAAGGAGAACGTCTTCCCCGGGACGACAACCCGCACCTTCTGCGGGACCCCGGAC c.1560
M C K E N V F P G T T T R T F C G T P D p.520
. | 15 . . . . . g.25905
TACATAGCCCCGGAG | ATCATTGCCTACCAGCCCTATGGGAAGTCTGTCGATTGGTGGTCC c.1620
Y I A P E | I I A Y Q P Y G K S V D W W S p.540
. . . | 16 . . . g.27446
TTTGGAGTTCTGCTGTATGAGATGTTGGCAGGACAG | CCTCCCTTCGATGGGGAGGACGAG c.1680
F G V L L Y E M L A G Q | P P F D G E D E p.560
. . . . . . g.27506
GAGGAGCTGTTTCAGGCCATCATGGAACAAACTGTCACCTACCCCAAGTCGCTTTCCCGG c.1740
E E L F Q A I M E Q T V T Y P K S L S R p.580
. . | 17 . . . . g.29140
GAAGCCGTGGCCATCTGCAAGGGG | TTCCTGACCAAGCACCCAGGGAAGCGCCTGGGCTCA c.1800
E A V A I C K G | F L T K H P G K R L G S p.600
. . . . . . g.29200
GGGCCTGATGGGGAACCTACCATCCGTGCACATGGCTTTTTCCGCTGGATTGACTGGGAG c.1860
G P D G E P T I R A H G F F R W I D W E p.620
. . . . | 18 . . g.29509
CGGCTGGAACGATTGGAGATCCCGCCTCCTTTCAGACCCCGCCCG | TGTGGCCGCAGCGGC c.1920
R L E R L E I P P P F R P R P | C G R S G p.640
. . . . . . g.29569
GAGAACTTTGACAAGTTCTTCACGCGGGCGGCGCCAGCGCTGACCCCTCCAGACCGCCTA c.1980
E N F D K F F T R A A P A L T P P D R L p.660
. . . . . . g.29629
GTCCTGGCCAGCATCGACCAGGCCGATTTCCAGGGCTTCACCTACGTGAACCCCGACTTC c.2040
V L A S I D Q A D F Q G F T Y V N P D F p.680
. . . . . g.29683
GTGCACCCGGATGCCCGCAGCCCCACCAGCCCAGTGCCTGTGCCCGTCATGTAA c.2094
V H P D A R S P T S P V P V P V M X p.697
. . . . . . g.29743
tctcacccgccgccactaggtgtccccaacgtcccctccgccgtgccggcggcagcccca c.*60
. . . . . . g.29803
cttcacccccaacttcaccaccccctgtcccattctagatcctgcaccccagcattccag c.*120
. . . . . . g.29863
ctctgcccccgcgggttctagacgcccctcccaagcgttcctggccttctgaactccata c.*180
. . . . . . g.29923
cagcctctacagccgtcccgcgttcaagacttgagcggagcccgatattctccctgacct c.*240
. . . . . . g.29983
tagcgttctggactctgccccaatcgggtccagagaccacaccactaaccatccccaact c.*300
. . . . . . g.30043
ccatggggttcgagactccatcttggtagttctgtgcctccccccagaccccgcccctgg c.*360
. . . . . . g.30103
ggaaatagcctcacggggttggctgttccagactcaggttccagaacagccctcggcctc c.*420
. . . . . . g.30163
cgaggctccccgcctccactctagttctagatgagtgggaggcgtgcccccctcctccag c.*480
. . . . . . g.30223
tacgtcccgctgctgtgctctggggatttctgggatatatggaggattctttccccagag c.*540
. . . . . . g.30283
gctcccaatcagcttttgttctagacttccccatcccgaagccatcacttctccccgcag c.*600
. . . . . . g.30343
cccgcctgccgtgcatggctcctgtctggctcggacccaccccaactctccccagtgcct c.*660
. . . . . . g.30403
gccactctctgggactctcctcctcccctcctcttcccttagcctctcccacccggccac c.*720
. . . g.30435
agctgctggagaataaatttgggatgctgatg c.*752
(downstream sequence)
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