(intronic numbering for coding DNA Reference Sequence)
         .         .         .         .         .      g.25274
gtgaggcctgctggaaggggtggggattacaaggaggctgagacttggagctag  c.424+54
--------------------- middle of intron ---------------------
          .         .         .         .         .           g.25328
      gggttcagtgcctcgagacctccctgccggccctgacctcccatggacctgcag  c.425-1
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