regulator of G protein signaling 9 binding protein (RGS9BP) - coding DNA reference sequence

(used for variant description)

(last modified November 26, 2020)

This file was created to facilitate the description of sequence variants on transcript NM_207391.2 in the RGS9BP gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NG_016751.1, covering RGS9BP transcript NM_207391.2.

Please note that introns are available by clicking on the exon numbers above the sequence.

 (upstream sequence)
                                                   .                g.5017
                                            actagaggtggggttag       c.-841

 .         .         .         .         .         .                g.5077
 cgcttggaagcaccgaccaacgtgagcgcaacgcggcagggacacctgaccccggcggcg       c.-781

 .         .         .         .         .         .                g.5137
 cccagcccctcggattgccagtcactgctcgctttggggcacggaggtgcccagtcctgc       c.-721

 .         .         .         .         .         .                g.5197
 ggggcacccgacgtcctgtcgccgacagggtccgggagtcagtatagctgggttctagtc       c.-661

 .         .         .         .         .         .                g.5257
 ccatcacaggcaaaaactccgcgggagcctggcccgctttttacctgggcctcagtttcc       c.-601

 .         .         .         .         .         .                g.5317
 ccatccgtaaaatagaacgggttggatctcccgagcgctaacattccagaactcggatgg       c.-541

 .         .         .         .         .         .                g.5377
 ggcgaaggggagggagggatgggccacccacacgtgacctccccgcgtggagccccgcct       c.-481

 .         .         .         .         .         .                g.5437
 accactgatccagggggtggcagctccggccgggacgagcggggtgggcgggtcctagga       c.-421

 .         .         .         .         .         .                g.5497
 aaccctacccggccgcccttggcagcgcctaaggcggagcgcgcggctctgcagcctgct       c.-361

 .         .         .         .         .         .                g.5557
 tgccccggagttggcacccacggaggatggggaccgcaccctcagcttcgcagggagcca       c.-301

 .         .         .         .         .         .                g.5617
 ccgtggaggccagggcggtgcagagacacgacgtgtgactcggagtgcgcctggggagga       c.-241

 .         .         .         .         .         .                g.5677
 tggacgagggagcgggggaccgctaacggggctccctctgcgcgccccgtccgcagaggc       c.-181

 .         .         .         .         .         .                g.5737
 gcacgtcgagggtcccgggcgggctccgtggacgttggcggtagcgccgagcgagtcacg       c.-121

 .         .         .         .         .         .                g.5797
 gaccatgaagagcgttcgtgccgcgcggcccaaggccgggatgggggttagccacatcct       c.-61

 .         .         .         .         .         .                g.5857
 gccgcgctgagggggaggctaacgggcgcgggcggccgggcccagccggagcccaccgcg       c.-1

          .         .         .         .         .         .       g.5917
 ATGGCGAGGGAGGAGTGCAAGGCGCTGCTGGACGGGCTCAACAAGACGACTGCGTGCTAC       c.60
 M  A  R  E  E  C  K  A  L  L  D  G  L  N  K  T  T  A  C  Y         p.20

          .         .         .         .         .         .       g.5977
 CACCACCTGGTGCTGACCGTCGGTGGCTCGGCGGACTCGCAGAACCTGCGGCAGGAGCTG       c.120
 H  H  L  V  L  T  V  G  G  S  A  D  S  Q  N  L  R  Q  E  L         p.40

          .         .         .         .         .         .       g.6037
 CAAAAGACGCGCCAGAAGGCGCAGGAGCTGGCGGTGTCCACCTGCGCCCGGCTGACTGCT       c.180
 Q  K  T  R  Q  K  A  Q  E  L  A  V  S  T  C  A  R  L  T  A         p.60

          .         .         .         .         .         .       g.6097
 GTGCTGCGCGACCGGGGCCTGGCCGCCGACGAGCGCGCCGAGTTCGAGCGGCTCTGGGTG       c.240
 V  L  R  D  R  G  L  A  A  D  E  R  A  E  F  E  R  L  W  V         p.80

          .         .         .         .         .         .       g.6157
 GCCTTCTCGGGCTGCCTGGACCTGCTGGAAGCGGACATGCGACGCGCGCTGGAGCTGGGC       c.300
 A  F  S  G  C  L  D  L  L  E  A  D  M  R  R  A  L  E  L  G         p.100

          .         .         .         .         .         .       g.6217
 GCCGCGTTCCCGCTGCACGCGCCGCGGCGGCCGCTGGTGCGCACAGGTGTGGCTGGCGCC       c.360
 A  A  F  P  L  H  A  P  R  R  P  L  V  R  T  G  V  A  G  A         p.120

          .         .         .         .         .         .       g.6277
 TCCTCCGGCGTGGCGGCGCGCGCGCTGAGCACCCGCAGCCTGCGGCTCGAGGCGGAGGGC       c.420
 S  S  G  V  A  A  R  A  L  S  T  R  S  L  R  L  E  A  E  G         p.140

          .         .         .         .         .         .       g.6337
 GACTTCGACGTCGCGGACCTGCGGGAGCTGGAGCGCGAGGTCCTTCAGGTGGGCGAGATG       c.480
 D  F  D  V  A  D  L  R  E  L  E  R  E  V  L  Q  V  G  E  M         p.160

          .         .         .         .         .         .       g.6397
 ATCGACAACATGGAGATGAAGGTCAACGTGCCCCGCTGGACCGTGCAAGCCCGGCAGGCG       c.540
 I  D  N  M  E  M  K  V  N  V  P  R  W  T  V  Q  A  R  Q  A         p.180

          .         .         .         .         .         .       g.6457
 GCGGGCGCCGAGCTCCTGTCCACGGTCAGCGCCGGCCCCTCCTCGGTCGTGTCCTTGCAG       c.600
 A  G  A  E  L  L  S  T  V  S  A  G  P  S  S  V  V  S  L  Q         p.200

          .         .         .         .         .         .       g.6517
 GAGCGCGGGGGGGGTTGCGACCCCAGGAAGGCCCTGGCCGCCATCCTTTTCGGCGCCGTG       c.660
 E  R  G  G  G  C  D  P  R  K  A  L  A  A  I  L  F  G  A  V         p.220

          .         .         .         .                           g.6565
 CTGCTGGCGGCTGTGGCCCTAGCCGTGTGCGTGGCGAAGCTGAGCTGA                   c.708
 L  L  A  A  V  A  L  A  V  C  V  A  K  L  S  X                     p.235

          .         .         .         .         .         .       g.6625
 cggacacccgacggccgcctgctgctgccgctccctcccctgagaaaagactcgggatgg       c.*60

          .         .         .         .         .         .       g.6685
 gtgtggggtctggcctgtgcaaggggagtggtcctaaaaccccgtgtgtgcatgggtaca       c.*120

          .         .         .         .         .         .       g.6745
 cgcgcgtttccagtgcacatctgcctgggcaggacacggtttcctcttgctggcccggga       c.*180

          .         .         .         .         .         .       g.6805
 ggagttaactttgcgccggccgtcagggcattaccgctaacgtctgcaggagctttattc       c.*240

          .         .         .         .         .         .       g.6865
 cctattaatagaaaaccgtcacagtgaccctagatccctccgagttaatgagttaacaca       c.*300

          .         .         .         .         .         .       g.6925
 tgtgctgttggggcgtctttacagggagtccgagttcggtgcccacccctgccagcgtcg       c.*360

          .         .         .         .         .         .       g.6985
 ccccctttctgcgtgggacagtttgaaaaggtgggtggggtggagtgaagtttggagagg       c.*420

          .         .         .         .         .         .       g.7045
 gacgctgtttggttctatgtggttggtctgtttcccggacaagaaaaattgcaatcaaat       c.*480

          .         .         .         .         .         .       g.7105
 gtcagcagcttttattaccttaatctttcagggcctaaatttaggagagtgtcccgagag       c.*540

          .         .         .         .         .         .       g.7165
 cagttcatacaaagggctttctctaagacgcgctacagcccttcctagcagagtttatcc       c.*600

          .         .         .         .         .         .       g.7225
 attcgtccccaagagcagctagaagagatttgaggtcatgacctcccactgccgctcagg       c.*660

          .         .         .         .         .         .       g.7285
 ggctgaccctatttaggaaaccaaagagggtgggttgaacctactctcacggacttggat       c.*720

          .         .         .         .         .         .       g.7345
 ccagtgcgcacacttgcctgcggaaaagggctctccccagccacccggagatgggggtaa       c.*780

          .         .         .         .         .         .       g.7405
 gaggaagagcagaggcttggggtagggccacctggtgtttaaacaggcactttctccttc       c.*840

          .         .         .         .         .         .       g.7465
 tctggggcttatttttgttcagaactagaccagagtgtttgaacctcctttgcaggaggg       c.*900

          .         .         .         .         .         .       g.7525
 ctgggaatcctctttagagcacttaatcctatttatcccctggaatgtgcgtgctggcca       c.*960

          .         .         .         .         .         .       g.7585
 gtaggagggctggctttggcagctccctgacccccgcgctgcccgcccctccggggtaat       c.*1020

          .         .         .         .         .         .       g.7645
 gtggcattactggcccacagaggttttgagccaatcagctctgagactgggttagaatgt       c.*1080

          .         .         .         .         .         .       g.7705
 aacagctttaacttgggatttaagaagcttttaaaaggtaataatactctgaaagaaaaa       c.*1140

          .         .         .         .         .         .       g.7765
 tgacgtaaccacagcgtgtactatgaaagctgttattttaataaagaacgctgggccatg       c.*1200

          .         .         .         .         .         .       g.7825
 aactcatacctgccaatgagtcaaacatagtatctttatgtagatacttagattactaaa       c.*1260

          .         .         .         .         .         .       g.7885
 tatatatttcatctacttctgaagttgatagtcttcccccccccccacttttttcttttt       c.*1320

                                                                    g.7894
 tgagacagg                                                          c.*1329

 (downstream sequence)

Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The Regulator of G protein signaling 9 binding protein protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.