selenium binding protein 1 (SELENBP1) - coding DNA reference sequence

(used for variant description)

(last modified March 18, 2018)

This file was created to facilitate the description of sequence variants on transcript NM_003944.3 in the SELENBP1 gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NC_000001.10, covering SELENBP1 transcript NM_003944.3.

Please note that introns are available by clicking on the exon numbers above the sequence.

 (upstream sequence)
                               .         .         .                g.5033
                            tataaattccctcccttcgctccttccccggaa       c.-61

 .         .         .         .         .         .                g.5093
 cagcggcctctgacaccagcacagcaaacccgccgggatcaaagtgtaccagtcggcagc       c.-1

      | 02   .         .         .         .         .         .    g.8021
 ATGG | CTACGAAATGTGGGAATTGTGGACCCGGCTACTCCACCCCTCTGGAGGCCATGAAA    c.60
 M  A |   T  K  C  G  N  C  G  P  G  Y  S  T  P  L  E  A  M  K      p.20

   | 03      .         .         .         .         .         .    g.8239
 G | GACCCAGGGAAGAGATCGTCTACCTGCCCTGCATTTACCGAAACACAGGCACTGAGGCC    c.120
 G |   P  R  E  E  I  V  Y  L  P  C  I  Y  R  N  T  G  T  E  A      p.40

          .         .         .         .         .     | 04   .    g.8551
 CCAGATTATCTGGCCACTGTGGATGTTGACCCCAAGTCTCCCCAGTATTGCCAG | GTCATC    c.180
 P  D  Y  L  A  T  V  D  V  D  P  K  S  P  Q  Y  C  Q   | V  I      p.60

          .         .         .         .         .         .       g.8611
 CACCGGCTGCCCATGCCCAACCTGAAGGACGAGCTGCATCACTCAGGATGGAACACCTGC       c.240
 H  R  L  P  M  P  N  L  K  D  E  L  H  H  S  G  W  N  T  C         p.80

          .         .         .         .         .         .       g.8671
 AGCAGCTGCTTCGGTGATAGCACCAAGTCGCGCACCAAGCTGGTGCTGCCCAGTCTCATC       c.300
 S  S  C  F  G  D  S  T  K  S  R  T  K  L  V  L  P  S  L  I         p.100

          .         .         .         .         .         .       g.8731
 TCCTCTCGCATCTATGTGGTGGACGTGGGCTCTGAGCCCCGGGCCCCAAAGCTGCACAAG       c.360
 S  S  R  I  Y  V  V  D  V  G  S  E  P  R  A  P  K  L  H  K         p.120

  | 05       .         .         .         .         .         .    g.9475
  | GTCATTGAGCCCAAGGACATCCATGCCAAGTGCGAACTGGCCTTTCTCCACACCAGCCAC    c.420
  | V  I  E  P  K  D  I  H  A  K  C  E  L  A  F  L  H  T  S  H      p.140

          .         .         .         .         .         .       g.9535
 TGCCTGGCCAGCGGGGAAGTGATGATCAGCTCCCTGGGAGACGTCAAGGGCAATGGCAAA       c.480
 C  L  A  S  G  E  V  M  I  S  S  L  G  D  V  K  G  N  G  K         p.160

   | 06      .         .         .         .         .         .    g.10889
 G | GGGGTTTTGTGCTGCTGGATGGGGAGACGTTCGAGGTGAAGGGGACATGGGAGAGACCT    c.540
 G |   G  F  V  L  L  D  G  E  T  F  E  V  K  G  T  W  E  R  P      p.180

          .         .         .         .         .         .       g.10949
 GGGGGTGCTGCACCGTTGGGCTATGACTTCTGGTACCAGCCTCGACACAATGTCATGATC       c.600
 G  G  A  A  P  L  G  Y  D  F  W  Y  Q  P  R  H  N  V  M  I         p.200

          .         .         .         .         .         .       g.11009
 AGCACTGAGTGGGCAGCTCCCAATGTCTTACGAGATGGCTTCAACCCCGCTGATGTGGAG       c.660
 S  T  E  W  A  A  P  N  V  L  R  D  G  F  N  P  A  D  V  E         p.220

      | 07   .         .         .         .         .         .    g.11337
 GCTG | GACTGTACGGGAGCCACTTATATGTATGGGACTGGCAGCGCCATGAGATTGTGCAG    c.720
 A  G |   L  Y  G  S  H  L  Y  V  W  D  W  Q  R  H  E  I  V  Q      p.240

          .         .         .         .         .         .       g.11397
 ACCCTGTCTCTAAAAGATGGGCTTATTCCCTTGGAGATCCGCTTCCTGCACAACCCAGAC       c.780
 T  L  S  L  K  D  G  L  I  P  L  E  I  R  F  L  H  N  P  D         p.260

          .         .         .         .         .         .       g.11457
 GCTGCCCAAGGCTTTGTGGGCTGCGCACTCAGCTCCACCATCCAGCGCTTCTACAAGAAC       c.840
 A  A  Q  G  F  V  G  C  A  L  S  S  T  I  Q  R  F  Y  K  N         p.280

     | 08    .         .         .         .         .         .    g.11945
 GAG | GGAGGTACATGGTCAGTGGAGAAGGTGATCCAGGTGCCCCCCAAGAAAGTGAAGGGC    c.900
 E   | G  G  T  W  S  V  E  K  V  I  Q  V  P  P  K  K  V  K  G      p.300

          .         .   | 09     .         .         .         .    g.12088
 TGGCTGCTGCCCGAAATGCCAG | GCCTGATCACCGACATCCTGCTCTCCCTGGACGACCGC    c.960
 W  L  L  P  E  M  P  G |   L  I  T  D  I  L  L  S  L  D  D  R      p.320

          .         .         .         .         .         .       g.12148
 TTCCTCTACTTCAGCAACTGGCTGCATGGGGACCTGAGGCAGTATGACATCTCTGACCCA       c.1020
 F  L  Y  F  S  N  W  L  H  G  D  L  R  Q  Y  D  I  S  D  P         p.340

          .         .     | 10   .         .         .         .    g.12489
 CAGAGACCCCGCCTCACAGGACAG | CTCTTCCTCGGAGGCAGCATTGTTAAGGGAGGCCCT    c.1080
 Q  R  P  R  L  T  G  Q   | L  F  L  G  G  S  I  V  K  G  G  P      p.360

          .         .         .         .         .        | 11.    g.12693
 GTGCAAGTGCTGGAGGACGAGGAACTAAAGTCCCAGCCAGAGCCCCTAGTGGTCAAG | GGA    c.1140
 V  Q  V  L  E  D  E  E  L  K  S  Q  P  E  P  L  V  V  K   | G      p.380

          .         .         .         .         .         .       g.12753
 AAACGGGTGGCTGGAGGCCCTCAGATGATCCAGCTCAGCCTGGATGGGAAGCGCCTCTAC       c.1200
 K  R  V  A  G  G  P  Q  M  I  Q  L  S  L  D  G  K  R  L  Y         p.400

          .         .         .         .         .       | 12 .    g.13033
 ATCACCACGTCGCTGTACAGTGCCTGGGACAAGCAGTTTTACCCTGATCTCATCAG | GGAA    c.1260
 I  T  T  S  L  Y  S  A  W  D  K  Q  F  Y  P  D  L  I  R  |  E      p.420

          .         .         .         .         .         .       g.13093
 GGCTCTGTGATGCTGCAGGTTGATGTAGACACAGTAAAAGGAGGGCTGAAGTTGAACCCC       c.1320
 G  S  V  M  L  Q  V  D  V  D  T  V  K  G  G  L  K  L  N  P         p.440

          .         .         .         .         .         .       g.13153
 AACTTCCTGGTGGACTTCGGGAAGGAGCCCCTTGGCCCAGCCCTTGCCCATGAGCTCCGC       c.1380
 N  F  L  V  D  F  G  K  E  P  L  G  P  A  L  A  H  E  L  R         p.460

          .         .         .                                     g.13192
 TACCCTGGGGGCGATTGTAGCTCTGACATCTGGATTTGA                            c.1419
 Y  P  G  G  D  C  S  S  D  I  W  I  X                              p.472

          .         .         .         .         .         .       g.13252
 actccaccctcatcacccacactccctattttgggccctcacttccttggggacctggct       c.*60

          .         .         .         .         .         .       g.13312
 tcattctgctctctcttggcacccgacccttggcagcatgtaccacacagccaagctgag       c.*120

          .         .         .         .         .         .       g.13372
 actgtggcaatgtgttgagtcatatacatttactgaccactgttgcttgttgctcactgt       c.*180

          .         .         .         .         .         .       g.13432
 gctgcttttccatgagctcttggaggcaccaagaaataaactcgtaaccctgtccttcag       c.*240

                                                                    g.13433
 a                                                                  c.*241

 (downstream sequence)

Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The Selenium binding protein 1 protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.