(intronic numbering for coding DNA Reference Sequence)
. . . . g.16542
gtaagtctgggcaaaggtgggaaggggtcgccagcaggaggggag c.1454+45
--------------------- middle of intron ---------------------
g.16543 . . . . g.16586
c.1455-44 atgggctgagatgcgctcagcctcaccactctgcttgtccccag c.1455-1
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