(used for variant description)
(last modified June 16, 2017)
This file was created to facilitate the description of sequence variants on transcript NM_147187.2 in the TNFRSF10B gene based on a coding DNA reference sequence following the HGVS recommendations.
The sequence was taken from NG_012145.1, covering TNFRSF10B transcript NM_147187.2.
(upstream sequence)
. . . . . g.5053
acttggacgcgcttgcggaggattgcgttgacgagactcttatttattgtcac c.-241
. . . . . . g.5113
caacctgtggtggaatttgcagttgcacattggatctgattcgccccgccccgaatgacg c.-181
. . . . . . g.5173
cctgcccggaggcagtgaaagtacagccgcgccgccccaagtcagcctggacacataaat c.-121
. . . . . . g.5233
cagcacgcggccggagaaccccgcaatctctgcgcccacaaaatacaccgacgatgcccg c.-61
. . . . . . g.5293
atctactttaagggctgaaacccacgggcctgagagactataagagcgttccctaccgcc c.-1
. . . . . . g.5353
ATGGAACAACGGGGACAGAACGCCCCGGCCGCTTCGGGGGCCCGGAAAAGGCACGGCCCA c.60
M E Q R G Q N A P A A S G A R K R H G P p.20
. . . . . . g.5413
GGACCCAGGGAGGCGCGGGGAGCCAGGCCTGGGCCCCGGGTCCCCAAGACCCTTGTGCTC c.120
G P R E A R G A R P G P R V P K T L V L p.40
. . | 02 . . . . g.30980
GTTGTCGCCGCGGTCCTGCTGTTG | GTCTCAGCTGAGTCTGCTCTGATCACCCAACAAGAC c.180
V V A A V L L L | V S A E S A L I T Q Q D p.60
. . . . . . g.31040
CTAGCTCCCCAGCAGAGAGCGGCCCCACAACAAAAGAGGTCCAGCCCCTCAGAGGGATTG c.240
L A P Q Q R A A P Q Q K R S S P S E G L p.80
. | 03 . . . . . g.43365
TGTCCACCTG | GACACCATATCTCAGAAGACGGTAGAGATTGCATCTCCTGCAAATATGGA c.300
C P P G | H H I S E D G R D C I S C K Y G p.100
. . . . . . g.43425
CAGGACTATAGCACTCACTGGAATGACCTCCTTTTCTGCTTGCGCTGCACCAGGTGTGAT c.360
Q D Y S T H W N D L L F C L R C T R C D p.120
| 04 . . . . . . g.44522
TCAG | GTGAAGTGGAGCTAAGTCCCTGCACCACGACCAGAAACACAGTGTGTCAGTGCGAA c.420
S G | E V E L S P C T T T R N T V C Q C E p.140
. . . . . | 05 . g.45589
GAAGGCACCTTCCGGGAAGAAGATTCTCCTGAGATGTGCCGGAAGTGCCGCACAGG | GTGT c.480
E G T F R E E D S P E M C R K C R T G | C p.160
. . . . . . g.45649
CCCAGAGGGATGGTCAAGGTCGGTGATTGTACACCCTGGAGTGACATCGAATGTGTCCAC c.540
P R G M V K V G D C T P W S D I E C V H p.180
. | 06 . . . . . g.45796
AAAGAATCAG | GCATCATCATAGGAGTCACAGTTGCAGCCGTAGTCTTGATTGTGGCTGTG c.600
K E S G | I I I G V T V A A V V L I V A V p.200
. . . . . . g.45856
TTTGTTTGCAAGTCTTTACTGTGGAAGAAAGTCCTTCCTTACCTGAAAGGCATCTGCTCA c.660
F V C K S L L W K K V L P Y L K G I C S p.220
| 07 . . . | 08 . . . g.46926
G | GTGGTGGTGGGGACCCTGAGCGTGTGGACAGA | AGCTCACAACGACCTGGGGCTGAGGAC c.720
G | G G G D P E R V D R | S S Q R P G A E D p.240
. . . . . . g.46986
AATGTCCTCAATGAGATCGTGAGTATCTTGCAGCCCACCCAGGTCCCTGAGCAGGAAATG c.780
N V L N E I V S I L Q P T Q V P E Q E M p.260
. . . . . . g.47046
GAAGTCCAGGAGCCAGCAGAGCCAACAGGTGTCAACATGTTGTCCCCCGGGGAGTCAGAG c.840
E V Q E P A E P T G V N M L S P G E S E p.280
| 09 . . . . . g.49978
CATCTGCTG | GAACCGGCAGAAGCTGAAAGGTCTCAGAGGAGGAGGCTGCTGGTTCCAGCA c.900
H L L | E P A E A E R S Q R R R L L V P A p.300
. . | 10 . . . . g.51241
AATGAAGGTGATCCCACTGAGA | CTCTGAGACAGTGCTTCGATGACTTTGCAGACTTGGTG c.960
N E G D P T E T | L R Q C F D D F A D L V p.320
. . . . . . g.51301
CCCTTTGACTCCTGGGAGCCGCTCATGAGGAAGTTGGGCCTCATGGACAATGAGATAAAG c.1020
P F D S W E P L M R K L G L M D N E I K p.340
. . . . . . g.51361
GTGGCTAAAGCTGAGGCAGCGGGCCACAGGGACACCTTGTACACGATGCTGATAAAGTGG c.1080
V A K A E A A G H R D T L Y T M L I K W p.360
. . . . . . g.51421
GTCAACAAAACCGGGCGAGATGCCTCTGTCCACACCCTGCTGGATGCCTTGGAGACGCTG c.1140
V N K T G R D A S V H T L L D A L E T L p.380
. . . . . . g.51481
GGAGAGAGACTTGCCAAGCAGAAGATTGAGGACCACTTGTTGAGCTCTGGAAAGTTCATG c.1200
G E R L A K Q K I E D H L L S S G K F M p.400
. . . g.51517
TATCTAGAAGGTAATGCAGACTCTGCCATGTCCTAA c.1236
Y L E G N A D S A M S X p.411
. . . . . . g.51577
gtgtgattctcttcaggaagtcagaccttccctggtttaccttttttctggaaaaagccc c.*60
. . . . . . g.51637
aactggactccagtcagtaggaaagtgccacaattgtcacatgaccggtactggaagaaa c.*120
. . . . . . g.51697
ctctcccatccaacatcacccagtggatggaacatcctgtaacttttcactgcacttggc c.*180
. . . . . . g.51757
attatttttataagctgaatgtgataataaggacactatggaaatgtctggatcattccg c.*240
. . . . . . g.51817
tttgtgcgtactttgagatttggtttgggatgtcattgttttcacagcacttttttatcc c.*300
. . . . . . g.51877
taatgtaaatgctttatttatttatttgggctacattgtaagatccatctacacagtcgt c.*360
. . . . . . g.51937
tgtccgacttcacttgatactatatgatatgaaccttttttgggtggggggtgcggggca c.*420
. . . . . . g.51997
gttcactctgtctcccaggctggagtgcaatggtgcaatcttggctcactatagccttga c.*480
. . . . . . g.52057
cctctcaggctcaagcgattctcccacctcagccatccaaatagctgggaccacaggtgt c.*540
. . . . . . g.52117
gcaccaccacgcccggctaattttttgtattttgtctagatataggggctctctatgttg c.*600
. . . . . . g.52177
ctcagggtggtctcgaattcctggactcaagcagtctgcccacctcagactcccaaagcg c.*660
. . . . . . g.52237
gtggaattagaggcgtgagcccccatgcttggccttacctttctacttttataattctgt c.*720
. . . . . . g.52297
atgttattattttatgaacatgaagaaactttagtaaatgtacttgtttacatagttatg c.*780
. . . . . . g.52357
tgaatagattagataaacataaaaggaggagacatacaatgggggaagaagaagaagtcc c.*840
. . . . . . g.52417
cctgtaagatgtcactgtctgggttccagccctccctcagatgtactttggcttcaatga c.*900
. . . . . . g.52477
ttggcaacttctacaggggccagtcttttgaactggacaaccttacaagtatatgagtat c.*960
. . . . . . g.52537
tatttataggtagttgtttacatatgagtcgggaccaaagagaactggatccacgtgaag c.*1020
. . . . . . g.52597
tcctgtgtgtggctggtccctacctgggcagtctcatttgcacccatagcccccatctat c.*1080
. . . . . . g.52657
ggacaggctgggacagaggcagatgggttagatcacacataacaatagggtctatgtcat c.*1140
. . . . . . g.52717
atcccaagtgaacttgagccctgtttgggctcaggagatagaagacaaaatctgtctccc c.*1200
. . . . . . g.52777
acgtctgccatggcatcaagggggaagagtagatggtgcttgagaatggtgtgaaatggt c.*1260
. . . . . . g.52837
tgccatctcaggagtagatggcccggctcacttctggttatctgtcaccctgagcccatg c.*1320
. . . . . . g.52897
agctgccttttagggtacagattgcctacttgaggaccttggccgctctgtaagcatctg c.*1380
. . . . . . g.52957
actcatctcagaaatgtcaattcttaaacactgtggcaacaggacctagaatggctgacg c.*1440
. . . . . . g.53017
cattaaggttttcttcttgtgtcctgttctattattgttttaagacctcagtaaccattt c.*1500
. . . . . . g.53077
cagcctctttccagcaaacccttctccatagtatttcagtcatggaaggatcatttatgc c.*1560
. . . . . . g.53137
aggtagtcattccaggagtttttggtcttttctgtctcaaggcattgtgtgttttgttcc c.*1620
. . . . . . g.53197
gggactggtttgggtgggacaaagttagaattgcctgaagatcacacattcagactgttg c.*1680
. . . . . . g.53257
tgtctgtggagttttaggagtggggggtgacctttctggtctttgcacttccatcctctc c.*1740
. . . . . . g.53317
ccacttccatctggcatcccacgcgttgtcccctgcacttctggaaggcacagggtgctg c.*1800
. . . . . . g.53377
ctgcctcctggtctttgcctttgctgggccttctgtgcaggacgctcagcctcagggctc c.*1860
. . . . . . g.53437
agaaggtgccagtccggtcccaggtcccttgtcccttccacagaggccttcctagaagat c.*1920
. . . . . . g.53497
gcatctagagtgtcagccttatcagtgtttaagatttttcttttatttttaatttttttg c.*1980
. . . . . . g.53557
agacagaatctcactctctcgcccaggctggagtgcaacggtacgatcttggctcagtgc c.*2040
. . . . . . g.53617
aacctccgcctcctgggttcaagcgattctcgtgcctcagcctccggagtagctgggatt c.*2100
. . . . . . g.53677
gcaggcacccgccaccacgcctggctaatttttgtatttttagtagagacggggtttcac c.*2160
. . . . . . g.53737
catgttggtcaggctggtctcgaactcctgacctcaggtgatccaccttggcctccgaaa c.*2220
. . . . . . g.53797
gtgctgggattacaggcgtgagccaccagccaggccaagctattcttttaaagtaagctt c.*2280
. . . . . . g.53857
cctgacgacatgaaataattgggggttttgttgtttagttacattaggctttgctatatc c.*2340
. . . . . . g.53917
cccaggccaaatagcatgtgacacaggacagccatagtatagtgtgtcactcgtggttgg c.*2400
. . . . . . g.53977
tgtcctttcatgcttctgccctgtcaaaggtccctatttgaaatgtgttataatacaaac c.*2460
. . . . . . g.54037
aaggaagcacattgtgtacaaaatacttatgtatttatgaatccatgaccaaattaaata c.*2520
. g.54055
tgaaaccttatataaaaa c.*2538
(downstream sequence)
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