yippee-like 2 (Drosophila) (YPEL2) - coding DNA reference sequence

(used for variant description)

(last modified July 21, 2023)
This file was created to facilitate the description of sequence variants on transcript NM_001005404.3 in the YPEL2 gene based on a coding DNA reference sequence following the HGVS recommendations.
The sequence was taken from NC_000017.10, covering YPEL2 transcript NM_001005404.3.
Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
                                         .         .                g.5028
                                 gccgcggcggtggcggagactgtggctt       c.-301

 .         .         .         .         .         .                g.5088
 taagagcgtgccgggagcccgagccccagccgggccgcgcttcgccgctgcgcaccccag       c.-241

 .         .         .         .         .     | 02   .             g.26538
 cggagccaagccccacgctggccggacagggccgcctgtcgccgg | gctgctgagaactag    c.-181

 .         .         .         .         .         .                g.26598
 ccctagacctctgcgtgagggttcttctgccgaagacatcaccagtgtgtggagcctgcc       c.-121

 .         .         .         .         .         .                g.26658
 acacccacccgctgccaaaccacggcctttacctgtgtcttccggtgtttcccgtgcgac       c.-61

 .         .         .         .         .         .                g.26718
 ccatcctgtgggagtgcctcgtgggctgccccagagttcaccccacactcagcagcacca       c.-1

          .         .         .         .         .         .       g.26778
 ATGGTGAAGATGACAAGATCGAAGACTTTCCAGGCATATCTGCCCTCCTGCCACCGGACC       c.60
 M  V  K  M  T  R  S  K  T  F  Q  A  Y  L  P  S  C  H  R  T         p.20

          .         .         .         .         .        | 03.    g.61638
 TACAGCTGCATTCACTGCAGAGCTCACTTGGCCAATCATGATGAACTAATTTCCAAG | TCA    c.120
 Y  S  C  I  H  C  R  A  H  L  A  N  H  D  E  L  I  S  K   | S      p.40

          .         .         .         .  | 04      .         .    g.62687
 TTCCAAGGAAGTCAAGGACGAGCATACCTCTTTAACTCAGT | AGTTAATGTGGGCTGTGGG    c.180
 F  Q  G  S  Q  G  R  A  Y  L  F  N  S  V  |  V  N  V  G  C  G      p.60

          .         .         .         .         .         .       g.62747
 CCTGCAGAAGAGCGAGTGTTGCTAACAGGACTGCATGCAGTCGCAGACATTTACTGTGAA       c.240
 P  A  E  E  R  V  L  L  T  G  L  H  A  V  A  D  I  Y  C  E         p.80

          .         .         . | 05       .         .         .    g.70439
 AACTGCAAAACCACTCTGGGCTGGAAATAC | GAACATGCTTTTGAAAGCAGCCAGAAATAT    c.300
 N  C  K  T  T  L  G  W  K  Y   | E  H  A  F  E  S  S  Q  K  Y      p.100

          .         .         .         .         .         .       g.70499
 AAAGAAGGCAAATACATCATTGAACTAGCACACATGATCAAGGACAATGGCTGGGACTGA       c.360
 K  E  G  K  Y  I  I  E  L  A  H  M  I  K  D  N  G  W  D  X         p.119

          .         .         .         .         .         .       g.70559
 ttggacagcatctacccaacccagtgtccacgtgaacgccattcaaccgaacattcttcc       c.*60

          .         .         .         .         .         .       g.70619
 caagcgtgagagagtgactgacacttggttccatccatttaggggccttgccatccgggg       c.*120

          .         .         .         .         .         .       g.70679
 catcctcccaccctgacgccatctttctggtgaccggcctctaaatcgctgtctctctgt       c.*180

          .         .         .         .         .         .       g.70739
 ctctttgctttgtatctgtttgtgagttgatcctggcttctctctctgttctagttttgg       c.*240

          .         .         .         .         .         .       g.70799
 ctgaaaacaaaacaacaaaaggaacagatccttgaccgcatggcggcagcccaccttggt       c.*300

          .         .         .         .         .         .       g.70859
 aagggccccagggcccatgcgagagctgcctgatggcctcttgtcaggagagcagtggca       c.*360

          .         .         .         .         .         .       g.70919
 cgggggcgtgaggaagagggaaaggggaaactctaagggtcctggcgcggggaaggggtg       c.*420

          .         .         .         .         .         .       g.70979
 gaagggtggaggtaggaacaaaattgcgccgctcctggagacctgataacttaggcttga       c.*480

          .         .         .         .         .         .       g.71039
 aataattgacttgtctaaaaggacaaagagaaaaaaaaaatacctcatgactgcattctc       c.*540

          .         .         .         .         .         .       g.71099
 tctgactagaagcttctgttcctgacaccaaatgtgccaggttagcaaatgagcacaaga       c.*600

          .         .         .         .         .         .       g.71159
 tgtggccctgattctagttggtggggcaagggcctggttctcctgggctgagtgggggag       c.*660

          .         .         .         .         .         .       g.71219
 tgtcctggcagcagcgagtgacctgggcagtggccaggtgggtgcgatgactctgatgcc       c.*720

          .         .         .         .         .         .       g.71279
 tcactcagtctctgggcaatcatcatctttgcctctagccaccgtagataaggtgtgaag       c.*780

          .         .         .         .         .         .       g.71339
 ggactgctgtttgcaatgggcttaccatccaaatatcccaaaggctttgaccagcaacca       c.*840

          .         .         .         .         .         .       g.71399
 agtaaaatcagtaattgaggagagcagggcacaaaggggctgcagtttgggagctcctga       c.*900

          .         .         .         .         .         .       g.71459
 agaaatggctcagatattgagtcagagaaataaaaagtaggatcagttagcaattctaac       c.*960

          .         .         .         .         .         .       g.71519
 tgcccttccttctgacccctcataagaggagtgtggtgagggaggggactgggtaggggt       c.*1020

          .         .         .         .         .         .       g.71579
 catcccaggaggaggggtttacattggaaccagttcaggttcggtgcatctttcctcttc       c.*1080

          .         .         .         .         .         .       g.71639
 ggttttacagtggcttccgtgggatcgtcaatttcttgttcttagagtttcgggtgtttt       c.*1140

          .         .         .         .         .         .       g.71699
 tctccagtcttgttactgtagactgtagaaagcacgggccccaggctctgagcttagtaa       c.*1200

          .         .         .         .         .         .       g.71759
 taacctggctggtagattcctcatgcccctaattgtcccacttaggcctgaatgtcttgc       c.*1260

          .         .         .         .         .         .       g.71819
 atggagagaaatctcctgtcagtgtggtccagcagcagggaggagttctgcccaaattcc       c.*1320

          .         .         .         .         .         .       g.71879
 gatatcaccccttcccccatccaagcatccttcgattagggaagtggagagcacatccct       c.*1380

          .         .         .         .         .         .       g.71939
 gtaaggcccataagagaaagaggagtttgttacatttaatcaacactgtgaagtctgttc       c.*1440

          .         .         .         .         .         .       g.71999
 tacagcaattcagccattacacagtatatgactgaaactcatttaactgggttaatttca       c.*1500

          .         .         .         .         .         .       g.72059
 tttcttagactgaatatattattgttaagatacgtgtgcgtgttaggtaattctcagcat       c.*1560

          .         .         .         .         .         .       g.72119
 ctcctccaagtaggccgaccttctcggaaaattcaccctaaaagtctcacaaaagaatga       c.*1620

          .         .         .         .         .         .       g.72179
 gttcatggggagattctgtaaagtgatgaactgagatgaaagcagccaacagcccaggag       c.*1680

          .         .         .         .         .         .       g.72239
 cttttcagaatagcgtctgcagcagaaccagtttccattcagagcgcgtccttggtggaa       c.*1740

          .         .         .         .         .         .       g.72299
 atgcttttttgtgtgtctccacgcgctgatggtggaatgggagccccaagacgtgtgggc       c.*1800

          .         .         .         .         .         .       g.72359
 ttagaaatcaacttttgttccccaaggcttcttgtccagatctttccagtgctttcatag       c.*1860

          .         .         .         .         .         .       g.72419
 ccctgggagatcaagttgttctccccactttactgcaaggtagactgaagttcagaagaa       c.*1920

          .         .         .         .         .         .       g.72479
 atactgaatttctgctcccagaagaatagtttctctggctcacaggcccaagttctcaat       c.*1980

          .         .         .         .         .         .       g.72539
 gaaatcgttttttaactttcacattcctaagctggcttcccggcacagaagccatggatt       c.*2040

          .         .         .         .         .         .       g.72599
 tcccctctctcccttccccctcctcaaggaaatagtcttcctttatggattttcattgga       c.*2100

          .         .         .         .         .         .       g.72659
 ctctttcctcagcgattgtcctggctgtttattgatagtccttcccataagaaaatgggg       c.*2160

          .         .         .         .         .         .       g.72719
 ttaaacatggggtaggtattttgtctttcaaactacaaatggaatgtggtgacataaact       c.*2220

          .         .         .         .         .         .       g.72779
 agacatggggtgccctcaagtttccaaggggaccaatgtgccactgttcttccttgggga       c.*2280

          .         .         .         .         .         .       g.72839
 tgaggcctttgactgttggatggatcagagcaggctccagtcagaccctggttctgaatg       c.*2340

          .         .         .         .         .         .       g.72899
 ttttttttttcggtgactatccagtgagccttcagtgggtgcaaggcgccatacttgctg       c.*2400

          .         .         .         .         .         .       g.72959
 tgagagagctgagtagagtgttggtttttccataactacagggggaaaaaaagtcattag       c.*2460

          .         .         .         .         .         .       g.73019
 gctttccctttgtgtcagtgaaaccaaaagtgcttcttacaacgttcgctctgttcatgg       c.*2520

          .         .         .         .         .         .       g.73079
 gttgtctatctaacattgagcagcattggagaggccacagctgagctatggagatgctaa       c.*2580

          .         .         .         .         .         .       g.73139
 attaactcatggcctcagtcagttcattctttaatttcctcaccaaattattgacttaga       c.*2640

          .         .         .         .         .         .       g.73199
 gcataaccaaagacctcattcattcaccccaggtgggttggggtaattggagtttgttgg       c.*2700

          .         .         .         .         .         .       g.73259
 tgaagtttgggggcggggtgttgggagtagagacagggtaaggggacgtgagaaaggaaa       c.*2760

          .         .         .         .         .         .       g.73319
 aggcatgaagttctatacctcagccagcagctgccttcgtttggaactgaagtccagcca       c.*2820

          .         .         .         .         .         .       g.73379
 gcagactctctagctccatctcccctgtgccaccctaggtcatatgaccttggccacctt       c.*2880

          .         .         .         .         .         .       g.73439
 ggagtagacccagacccctcgggacccgggacattagtctcaggctgctgatggattgat       c.*2940

          .         .         .         .         .         .       g.73499
 ttgacatgaaccaaacacagccaaactcgatacccacaagctgtcagctgaacctgactg       c.*3000

          .         .         .         .         .         .       g.73559
 agtgttcttcctgagttcacgaggataggctagagtgcatttttactggtggatcagtgt       c.*3060

          .         .         .         .         .         .       g.73619
 gtgcgaaagagatgaccctttataaagagattttcaagtggatatatataaaagaaacag       c.*3120

          .         .         .         .         .         .       g.73679
 ttgcttgtaaaatatacttttgtaaataatatttaattttttaaataatatatttggtgc       c.*3180

          .         .         .         .         .         .       g.73739
 tgttttctcagatcccctgagagcactttttattttccttttaaattctatggtttcctt       c.*3240

          .         .         .         .         .         .       g.73799
 tgcatttcttgaagtatattttaagggaaacagtgatcaccaatacatgttttcagtttt       c.*3300

          .         .         .         .         .         .       g.73859
 ttttttttttaaggtctctatcactttaatctggatcaaggctttgaagcaatgcctctc       c.*3360

          .         .         .         .         .         .       g.73919
 tgcattttttccccagtggaacagactctgcagtacattaatcaggttgagaattgaaat       c.*3420

          .         .         .         .         .         .       g.73979
 attttcttgcatcagtattggctagaaaagaaaataaataaaaccaagttaatttagtag       c.*3480

          .         .         .         .         .         .       g.74039
 taacaacttacagtgattcttcctgttggaagaatttccaacaaatcagaatcacgtttt       c.*3540

          .         .         .         .         .         .       g.74099
 tagttgtgcgtgtgcgcgcacacgtgtgtaaaaagcactttcgattgtgcctcctgtttt       c.*3600

          .         .         .         .         .         .       g.74159
 ctcgagtggggacactttaactacagtttacacctcgggcgcataaagtttttcttctct       c.*3660

          .         .         .         .         .         .       g.74219
 ttctctctggttgtttctgtttctgagtggaccaacagcagaacccacgaggatttgttt       c.*3720

          .         .         .         .         .         .       g.74279
 tgagtatggagctgttgcgggtttgctcctttttcttgctttgcgtgctcagtttttaca       c.*3780

          .         .         .         .         .         .       g.74339
 gactgtaaaggagatgtgttgtttgtgaagatggagcagagtcaaatctgtgcttctaac       c.*3840

          .         .         .         .         .         .       g.74399
 tgagatgagagtgtattaatcacgtatcgcagggctccagctgttttagaagccacatca       c.*3900

          .         .         .         .         .         .       g.74459
 tgttaaacattaactggtttggattaaaagaacattaatattataatacacatatcttag       c.*3960

          .         .         .         .         .         .       g.74519
 tggtaaacagctttttttttttaaggtcagattgcctcaggtttagaaagaggctgagaa       c.*4020

          .         .         .         .         .         .       g.74579
 atcaaatcttgaacacaatcaacttacatattttaaaggaatctgcctcaaatgagaaaa       c.*4080

          .         .         .         .         .         .       g.74639
 tatgctagttatctagatagaggaaagagatatttacttttttaaaaattaaaatagtta       c.*4140

          .         .         .         .         .         .       g.74699
 tgaaatctggcagaaaaggtaaagcctagaagaaactatgaaagctattctcatgttacc       c.*4200

          .         .         .         .         .         .       g.74759
 aaattctatctgcgcatatgtttttgtataacatttcggtgacagtgggagtcggttccc       c.*4260

          .         .         .         .         .         .       g.74819
 tttcccaacctgcagagactatcttccaatacagaatctgtctatttatgcttgtgttta       c.*4320

          .         .         .         .         .         .       g.74879
 caaactgtatttgttgggtttgggtttttgttttctttggtggcatttttcaggtcactt       c.*4380

          .         .         .         .         .         .       g.74939
 tgcttctataacaaaggtaattgttttcaaataatttgtcttcaccttttcctgtatttg       c.*4440

          .         .         .         .         .         .       g.74999
 tacatagtgattcagtattagagaaaagtgcattgtttctgtcatatttccaatctgtgt       c.*4500

          .         .         .         .                           g.75043
 tggtgctcatttgagaaaataaaagttttcaaatattaactctt                       c.*4544

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10^th nucleotide is indicated by a "." above the sequence. The Yippee-like 2 (Drosophila) protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10^th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift variants, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.