Transcript #00024029

Transcript name transcript variant b
Gene name KRAS (v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog)
Chromosome 12
Transcript - NCBI ID NM_004985.3
Transcript - Ensembl ID -
Protein - NCBI ID NP_004976.2
Protein - Ensembl ID -
Protein - Uniprot ID -
Exon/intron information Exon/intron information table: HTML, Txt
Remarks -


Variants

59 entries on 1 page. Showing entries 1 - 59.
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Affects function     

Exon     

AscendingDNA change (cDNA)     

ClassClinical     

RNA change     

Protein     
-?/. - c.24A>G likely benign r.(?) p.(=)
?/. 2 c.32_35delinsGTGC - r.(?) p.(Ala11_Gly12delinsGlyAla)
?/. - c.34G>A VUS r.(?) p.(Gly12Ser)
+?/. 1 c.34G>A - r.(?) p.(Gly12Ser)
?/. 2 c.34_35delinsCT - r.(?) p.(Gly12Leu)
?/. 2 c.35G>A - r.(?) p.(Gly12Asp)
+/. - c.35G>A pathogenic r.(?) p.(Gly12Asp)
+/. 2 c.35G>T - r.(?) p.(Gly12Val)
+/. - c.35G>T - r.(?) p.(Gly12Val)
?/. 2 c.37G>T - r.(?) p.(Gly13Cys)
+/. - c.37G>T - r.(?) p.(Gly13Cys)
+/. 2 c.38G>A - r.(?) p.(Gly13Asp)
+/. - c.38G>A pathogenic r.(?) p.(Gly13Asp)
+/. - c.40G>A pathogenic r.(?) p.(Val14Ile)
+?/. - c.40G>A likely pathogenic r.(?) p.(Val14Ile)
+?/. - c.53C>T likely pathogenic r.(?) p.(Ala18Val)
?/. 2 c.64C>A - r.(?) p.(Gln22Lys)
+/. - c.65A>G pathogenic r.(?) p.(Gln22Arg)
+?/. - c.68T>G likely pathogenic r.(?) p.(Leu23Arg)
+/. - c.108A>G pathogenic r.(?) p.(Ile36Met)
+/. - c.108A>G pathogenic r.(?) p.(Ile36Met)
+?/. 2 c.178G>C - r.(?) p.(Gly60Arg)
+?/. - c.179G>A likely pathogenic r.(?) p.(Gly60Asp)
+?/. - c.182A>C ACMG: 4 r.(?) p.(Gln61Pro)
+?/. 3 c.182A>T - r.(?) p.(Gln61Leu)
+?/. 3 c.183A>T - r.(?) p.(Gln61His)
+/. - c.211T>C pathogenic r.(?) p.(Tyr71His)
+?/. - c.214A>C likely pathogenic r.(?) p.(Met72Leu)
+?/. - c.347A>G likely pathogenic r.(?) p.(Asn116Ser)
?/. - c.400G>A VUS r.(?) p.(Ala134Thr)
+/. 4 c.440A>G ACMG: 5 r.(?) p.(Lys147Arg)
-?/. - c.450+3A>G likely benign r.spl? p.?
-/. - c.451-5749del benign r.(=) p.(=)
-?/. - c.451-5669A>G likely benign r.(=) p.(=)
?/. - c.451-5622G>A VUS r.(=) p.(=)
-/. - c.451-5617G>A benign r.(=) p.(=)
-/. - c.451-5617G>A benign r.(=) p.(=)
-?/. - c.451-5609G>A likely benign r.(=) p.(=)
-?/. - c.451-5604T>A likely benign r.(=) p.(=)
?/. - c.451-5560T>A VUS r.(=) p.(=)
-?/. - c.451-5535A>C likely benign r.(=) p.(=)
-?/. - c.451-5535A>C likely benign r.(=) p.(=)
-?/. - c.451-5535A>C likely benign r.(=) p.(=)
-?/. - c.451-5521G>A likely benign r.(=) p.(=)
-/. - c.451-18A>G benign r.(=) p.(=)
-/. - c.451-9G>A benign r.(=) p.(=)
-/. - c.451-7A>T benign r.(=) p.(=)
+/. - c.458A>T pathogenic r.(?) p.(Asp153Val)
-/. - c.519T>C benign r.(?) p.(=)
-/. - c.519T>C benign r.(?) p.(=)
-/. - c.519T>C benign r.(?) p.(=)
-?/. - c.531_533del likely benign r.(?) p.(Lys180del)
?/. - c.531_533del VUS r.(?) p.(Lys180del)
?/. - c.531_533del VUS r.(?) p.(Lys180del)
-?/. 5 c.*177T>G - r.(=) p.(=)
-/. - c.*512T>C benign r.(=) p.(=)
-?/. 5 c.*2888A>G - r.(=) p.(=)
-?/. - c.*5484C>A likely benign r.(=) p.(=)
?/. - c.*5578C>T VUS r.(=) p.(=)
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