Variant #0000167051 (NC_000001.10:g.[171076835A>G;171086305T>C], FMO3(NM_001002294.2):c.[341A>G;1322T>C])

Chromosome 1
Allele Parent #1
Affects function (as reported) Affects function
Affects function (by curator) Affects function
Classification method -
Clinical classification NA
DNA change (genomic) (Relative to hg19 / GRCh37) g.[171076835A>G;171086305T>C]
DNA change (hg38) -
Published as -
ISCN -
DB-ID FMO3_000000 See all 4 reported entries
Variant remarks cDNA expression cloning in E.coli showes lower Kcat/Km for N-oxygenation of trimethylamine (0.22) and benzydamine (0.16)
Reference PubMed: Shimizu 2012
ClinVar ID -
dbSNP ID -
Origin In vitro (cloned)
Segregation -
Frequency -
Re-site -
VIP 0
Methylation -
Average frequency (gnomAD v.2.1.1) Genomic location of variant could not be determined
Owner Ornicha Prapapan
Database submission license No license selected
Created by Ornicha Prapapan




Variant on transcripts


Gene     

AscendingTranscript     

Affects function     

Exon     

DNA change (cDNA)     

Haplotype     

RNA change     

Protein     
FMO3 NM_001002294.2 +/+ 4_9 c.[341A>G;1322T>C] - - p.[Asn114Ser;Ile441Thr]