Variant #0000167064 (NC_000001.10:g.171083398T>C, FMO3(NM_001002294.2):c.1079T>C)

Chromosome 1
Allele Unknown
Affects function (as reported) Affects function
Affects function (by curator) Affects function
Classification method -
Clinical classification NA
DNA change (genomic) (Relative to hg19 / GRCh37) g.171083398T>C
DNA change (hg38) g.171114258T>C
Published as -
ISCN -
DB-ID FMO3_000043 See all 3 reported entries
Variant remarks increased activity for TMA (5-fold), methimazole (3-fold) and 5-DPT (2-fold) via increase in Vmax
Reference PubMed: Furnes 2003, PubMed: Lattard 2003
ClinVar ID -
dbSNP ID rs28363581
Origin In vitro (cloned)
Segregation -
Frequency -
Re-site -
VIP 0
Methylation -
Average frequency (gnomAD v.2.1.1) 0.00036 View details
Owner Ornicha Prapapan
Database submission license No license selected
Created by Ornicha Prapapan
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Variant on transcripts


Gene     

AscendingTranscript     

Affects function     

Exon     

DNA change (cDNA)     

Haplotype     

RNA change     

Protein     
FMO3 NM_001002294.2 +/+ 7 c.1079T>C - r.(?) p.Leu360Pro