Variant #0000171441 (NC_000008.10:g.23058220T>G, NM_003844.3:c.683A>C (TNFRSF10A))
Individual ID |
00105390 |
Chromosome |
8 |
Allele |
Unknown |
Affects function (as reported) |
Effect unknown |
Affects function (by curator) |
Effect unknown |
Classification method |
- |
Clinical classification |
VUS |
DNA change (genomic) (Relative to hg19 / GRCh37) |
g.23058220T>G |
DNA change (hg38) |
g.23200707T>G |
Published as |
- |
ISCN |
- |
DB-ID |
TNFRSF10A_000005 See all 6 reported entries |
Variant remarks |
659 colorectal cancer patients were sequenced for these two variants. Variant 683G>C did not appear to be associated with an increased colorectal cancer risk. The 683C-626C haplotype conferred a 2.4 fold colorectal cancer risk. |
Reference |
PubMed: Frank 2006 |
ClinVar ID |
- |
dbSNP ID |
rs20576 |
Origin |
Unknown |
Segregation |
- |
Frequency |
- |
Re-site |
- |
VIP |
- |
Methylation |
- |
Average frequency (gnomAD v.2.1.1) |
0.15189 View details |
Owner |
Zoe Baily |
Database submission license |
No license selected |
Created by |
Zoe Baily |
Date created |
2012-04-26 15:18:20 +02:00 (CEST) |
Date last edited |
2017-06-23 12:26:32 +02:00 (CEST) |

Variant on transcripts
Screenings
|
Screenscraping/webscraping (downloading large amounts of data using scripts) is strictly prohibited.
Use our APIs to retrieve data.
|