Variant #0000179034 (NC_000012.11:g.25378558T>C, KRAS(NM_004985.3):c.440A>G)

Individual ID 00111412
Chromosome 12
Allele Unknown
Affects function (as reported) Affects function
Affects function (by curator) Not classified
Classification method ACMG
Clinical classification pathogenic
DNA change (genomic) (Relative to hg19 / GRCh37) g.25378558T>C
DNA change (hg38) g.25225624T>C
Published as -
ISCN -
DB-ID KRAS_000015
Variant remarks -
Reference -
ClinVar ID -
dbSNP ID -
Origin Germline/De novo (untested)
Segregation yes
Frequency -
Re-site -
VIP 0
Methylation -
Average frequency (gnomAD v.2.1.1) Variant not found in online data sets
Owner Bernt Popp
Database submission license No license selected
Created by Bernt Popp
Options




Variant on transcripts


Gene     

AscendingTranscript     

Affects function     

Exon     

DNA change (cDNA)     

RNA change     

Protein     
KRAS NM_004985.3 +/. 4 c.440A>G r.(?) p.(Lys147Arg)



Screenings


AscendingScreening ID     

Template     

Technique     

Tissue     

Remarks     

Genes screened     

Variants found     

Owner     
0000111877 DNA SEQ-NG - - KRAS 1 Bernt Popp