Variant #0000679474 (NC_000012.11:g.25368380T>G, KRAS(NM_004985.3):c.451-5535A>C)

Chromosome 12
Allele Unknown
Affects function (as reported) Probably does not affect function
Affects function (by curator) Not classified
Classification method -
Clinical classification likely benign
DNA change (genomic) (Relative to hg19 / GRCh37) g.25368380T>G
DNA change (hg38) -
Published as KRAS(NM_033360.3):c.565A>C (p.M189L), KRAS(NM_033360.4):c.565A>C (p.M189L)
ISCN -
DB-ID KRAS_000021 See all 4 reported entries
Variant remarks VKGL data sharing initiative Nederland
Reference -
ClinVar ID -
dbSNP ID -
Origin CLASSIFICATION record
Segregation -
Frequency -
Re-site -
VIP -
Methylation -
Average frequency (gnomAD v.2.1.1) 0.00029 View details
Owner VKGL-NL_AMC
Database submission license Creative Commons Attribution-NonCommercial-ShareAlike 4.0 InternationalCreative Commons License
Created by VKGL-NL_AMC
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Variant on transcripts


Gene     

AscendingTranscript     

Affects function     

Exon     

DNA change (cDNA)     

RNA change     

Protein     
LYRM5 NM_001001660.2 -?/. - c.*11134T>G r.(=) p.(=)
KRAS NM_004985.3 -?/. - c.451-5535A>C r.(=) p.(=)