All variants in the IL10 gene

Information The variants shown are described using the NM_000572.2 transcript reference sequence.

31 entries on 1 page. Showing entries 1 - 31.
Legend   How to query  

Effect     

Exon     

AscendingDNA change (cDNA)     

RNA change     

Protein     

Classification method     

Clinical classification     

DNA change (genomic) (hg19)     

DNA change (hg38)     

Published as     

ISCN     

DB-ID     

Variant remarks     

Reference     

ClinVar ID     

dbSNP ID     

Origin     

Segregation     

Frequency     

Re-site     

VIP     

Methylation     

Owner     
-?/. - c.43G>A r.(?) p.(Gly15Arg) - likely benign g.206945738C>T g.206772393C>T IL10(NM_000572.2):c.43G>A (p.(Gly15Arg)), IL10(NM_000572.3):c.43G>A (p.G15R) - IL10_000009 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
-?/. - c.43G>A r.(?) p.(Gly15Arg) - likely benign g.206945738C>T g.206772393C>T IL10(NM_000572.2):c.43G>A (p.(Gly15Arg)), IL10(NM_000572.3):c.43G>A (p.G15R) - IL10_000009 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - VKGL-NL_Rotterdam
-?/. - c.43G>A r.(?) p.(Gly15Arg) - likely benign g.206945738C>T g.206772393C>T IL10(NM_000572.2):c.43G>A (p.(Gly15Arg)), IL10(NM_000572.3):c.43G>A (p.G15R) - IL10_000009 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - VKGL-NL_Leiden
?/. - c.118A>G r.(?) p.(Met40Val) - VUS g.206945663T>C - - - IL10_000018 - PubMed: Luo 2021, Journal: Luo 2021 - - Germline - - - - - Liu Wenbing
?/. - c.133C>T r.(?) p.(Arg45*) - VUS g.206945648G>A - IL10(NM_000572.3):c.133C>T (p.R45*) - IL10_000019 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - VKGL-NL_Rotterdam
-?/. - c.165+8T>C r.(=) p.(=) - likely benign g.206945608A>G g.206772263A>G IL10(NM_000572.3):c.165+8T>C - IL10_000016 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - VKGL-NL_Utrecht
./. - c.165+235C>T r.(=) p.(=) - VUS g.206945381G>A g.206772036G>A - - IL10_000012 for details see the Uveogene database PubMed: Churchill 2010 - rs2222202 Germline - 166/396 cases - 0 - Peizeng Yang
./. - c.165+235C>T r.(=) p.(=) - VUS g.206945381G>A g.206772036G>A - - IL10_000012 for details see the Uveogene database PubMed: González-Escribano 2013 - rs2222202 Germline - 207/608 cases - 0 - Peizeng Yang
./. - c.165+305T>G r.(=) p.(=) - VUS g.206945311A>C g.206771966A>C - - IL10_000011 for details see the Uveogene database PubMed: Churchill 2010 - rs3024490 Germline - 192/396 cases - 0 - Peizeng Yang
./. - c.165+305T>G r.(=) p.(=) - VUS g.206945311A>C g.206771966A>C - - IL10_000011 for details see the Uveogene database PubMed: Song 2017 - rs3024490 Germline - 563/738 cases - 0 - Peizeng Yang
./. - c.165+305T>G r.(=) p.(=) - VUS g.206945311A>C g.206771966A>C - - IL10_000011 for details see the Uveogene database PubMed: Yang 2008 - rs3024490 Germline - 639/2412 cases - 0 - Peizeng Yang
./. - c.166-192A>C r.(=) p.(=) - VUS g.206944952T>G g.206771607T>G - - IL10_000010 for details see the Uveogene database PubMed: Yang 2015 - rs3021094 Germline - 289/600 cases - 0 - Peizeng Yang
-/. - c.166-101T>G r.(=) p.(=) - benign g.206944861A>C g.206771516A>C IL10(NM_000572.3):c.166-101T>G - IL10_000008 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
./. - c.166-101T>G r.(=) p.(=) - VUS g.206944861A>C g.206771516A>C - - IL10_000008 for details see the Uveogene database PubMed: Remmers 2017 - rs1518110 Germline - 1398/3800 cases - 0 - Peizeng Yang
./. - c.166-101T>G r.(=) p.(=) - VUS g.206944861A>C g.206771516A>C - - IL10_000008 for details see the Uveogene database PubMed: Song 2017 - rs1518110 Germline - 175/738 cases - 0 - Peizeng Yang
-?/. - c.166-86del r.(=) p.(=) - likely benign g.206944856del g.206771511del IL10(NM_000572.3):c.166-86delA - IL10_000015 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - VKGL-NL_Utrecht
-?/. - c.190T>C r.(?) p.(Leu64=) - likely benign g.206944736A>G - IL10(NM_000572.3):c.190T>C (p.L64=) - IL10_000017 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - VKGL-NL_Rotterdam
-/. - c.225+56A>G r.(=) p.(=) - benign g.206944645T>C g.206771300T>C IL10(NM_000572.3):c.225+56A>G - IL10_000007 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
./. - c.225+56A>G r.(=) p.(=) - VUS g.206944645T>C g.206771300T>C - - IL10_000007 for details see the Uveogene database PubMed: Gül 2010 - rs1518111 Germline - 317/1322 cases - 0 - Peizeng Yang
./. - c.225+56A>G r.(=) p.(=) - VUS g.206944645T>C g.206771300T>C - - IL10_000007 for details see the Uveogene database PubMed: Gül 2010 - rs1518111 Germline - 882/1161 cases - 0 - Peizeng Yang
./. - c.225+56A>G r.(=) p.(=) - VUS g.206944645T>C g.206771300T>C - - IL10_000007 for details see the Uveogene database PubMed: Song 2017 - rs1518111 Germline - 175/738 cases - 0 - Peizeng Yang
./. - c.225+56A>G r.(=) p.(=) - VUS g.206944645T>C g.206771300T>C - - IL10_000007 for details see the Uveogene database PubMed: Yang 2014 - rs1518111 Germline - 230/814 cases - 0 - Peizeng Yang
?/. - c.374G>A r.(?) p.(Arg125His) - VUS g.206944256C>T g.206770911C>T IL10(NM_000572.3):c.374G>A (p.R125H) - IL10_000013 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - VKGL-NL_Groningen
-/. - c.378+19T>C r.(=) p.(=) - benign g.206944233A>G g.206770888A>G IL10(NM_000572.3):c.378+19T>C - IL10_000006 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
./. - c.378+19T>C r.(=) p.(=) - VUS g.206944233A>G g.206770888A>G - - IL10_000006 for details see the Uveogene database PubMed: Song 2017 - rs1554286 Germline - 187/738 cases - 0 - Peizeng Yang
./. - c.378+19T>C r.(=) p.(=) - VUS g.206944233A>G g.206770888A>G - - IL10_000006 for details see the Uveogene database PubMed: Yang 2015 - rs1554286 Germline - 551/738 cases - 0 - Peizeng Yang
-/. - c.378+140A>T r.(=) p.(=) - benign g.206944112T>A g.206770767T>A IL10(NM_000572.3):c.378+140A>T - IL10_000005 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
-/. - c.379-112A>G r.(=) p.(=) - benign g.206943351T>C g.206770006T>C IL10(NM_000572.3):c.379-112A>G - IL10_000004 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
-/. - c.379-58T>C r.(=) p.(=) - benign g.206943297A>G g.206769952A>G IL10(NM_000572.3):c.379-58T>C - IL10_000003 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
-?/. - c.514A>G r.(?) p.(Met172Val) - likely benign g.206942004T>C g.206768659T>C IL10(NM_000572.3):c.514A>G (p.M172V) - IL10_000002 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
-/. - c.*117T>C r.(=) p.(=) - benign g.206941864A>G g.206768519A>G IL10(NM_000572.3):c.*117T>C - IL10_000001 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - VKGL-NL_Utrecht
Legend   How to query