MSH2 variants classified by the InSiGHT consortium: criteria used for classification are available here. We encourage submission of relevant unpublished information to assist in the classification of variants via LOVD or this template which can be emailed to the curator.

APC (adenomatous polyposis coli) CDH1 (cadherin 1, type 1, E-cadherin (epithelial)) EPCAM (epithelial cell adhesion molecule) GALNT12 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalacto...) MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)) MLH3 (mutL homolog 3 (E. coli)) MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)) MSH6 (mutS homolog 6 (E. coli)) MUTYH (MUTYH (mutY homolog (E. coli)) PMS2 (PMS2 postmeiotic segregation increased 2 (S. cerevisiae))