Full data view for gene MSH6


MSH6 variants classified by the InSiGHT consortium: criteria used for classification are available here. We encourage submission of relevant unpublished information to assist in the classification of variants via LOVD or this template which can be emailed to the curator.
Information The variants shown are described using the NM_000179.2 transcript reference sequence.

91 entries on 1 page. Showing entries 1 - 91.
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Effect     

Exon     

AscendingDNA change (cDNA)     

ClassClinical     

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Reference     

ClinVar ID     

dbSNP ID     

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Frequency     

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-/. - c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - MSH6(NM_000179.2):c.116G>A (p.G39E) - MSH6_000915 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-/. - c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - MSH6(NM_000179.2):c.116G>A (p.G39E) - MSH6_000915 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-/. - c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - MSH6(NM_000179.2):c.116G>A (p.G39E) - MSH6_000915 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-/. - c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - MSH6(NM_000179.2):c.116G>A (p.G39E) - MSH6_000915 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-/. - c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - MSH6(NM_000179.2):c.116G>A (p.G39E) - MSH6_000915 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-/- 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 Insight class: 1 - - - SUMMARY record - - - 0 - - - - - - - - - - - - - - - - - - -
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 - contributed by Dept. of Dr Vaccaro - - Germline - - - 0 - DNA SEQ - - ? - contributed by Dept. of Dr Vaccaro - - - Argentina - - 0 - - 1 Angela Solano & F Cardoso
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 - contributed by Dept. of Dr Vaccaro - - Germline - - - 0 - DNA SEQ - - ? - contributed by Dept. of Dr Vaccaro - - - Argentina - - 0 - - 1 Angela Solano & F Cardoso
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 - contributed by Dept. of Dr Vaccaro - - Germline - - - 0 - DNA SEQ - - ? - contributed by Dept. of Dr Vaccaro - - - Argentina - - 0 - - 1 Angela Solano & F Cardoso
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 - contributed by Dept. of Dr Vaccaro - - Germline - - - 0 - DNA SEQ - - ? - contributed by Dept. of Dr Vaccaro - - - Argentina - - 0 - - 1 Angela Solano & F Cardoso
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 - contributed by Dept. of Dr Vaccaro - - Germline - - - 0 - DNA SEQ - - ? - contributed by Dept. of Dr Vaccaro - - - Argentina - - 0 - - 1 Angela Solano & F Cardoso
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 - contributed by Dept. of Dr Vaccaro - - Germline - - - 0 - DNA SEQ - - ? - contributed by Dept. of Dr Vaccaro - - - Argentina - - 0 - - 1 Angela Solano & F Cardoso
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 - contributed by Dept. of Dr Vaccaro - - Germline - - - 0 - DNA SEQ - - ? - contributed by Dept. of Dr Vaccaro - - - Argentina - - 0 - - 1 Angela Solano & F Cardoso
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Maternal (inferred) g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA MLPA, SEQ - screen data 2012-01-01 HNPCC - - 2 Gen;2 cases CRC 58,42;2xbowel polyps. F - - - - 0 - - 1 Ruth Armstrong
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Paternal (inferred) g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA MLPA, SEQ - screen data 2011-01-01 HNPCC - - 2 Gen; 2 cases CRC 55,48;1 case endometrial 71 (Amsterdam II) F - - - - 0 - - 1 Ruth Armstrong
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA MLPA, SEQ - screen data 2012-01-01 HNPCC - - 2 Gen ;2casesCRC 18,66 F - - - - 0 - - 1 Ruth Armstrong
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Parent #2 g.48010488G>A - - - MSH6_000915 - PubMed: Hirata 2008 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 - PubMed: Hirata 2008 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - - - MSH6_000915 no significant association with breast cancer risk PubMed: Smith 2008 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Parent #2 g.48010488G>A - - - MSH6_000915 no significant association with breast cancer risk PubMed: Smith 2008 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA PCR, SEQ - - CRC - - - ? - Germany - - 0 - - 1 Peter Propping, Prof. Dr. med.
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA PCR, SEQ - - CRC - - - ? - Germany - - 0 - - 1 Peter Propping, Prof. Dr. med.
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - G>A at 116 - MSH6_000915 - PubMed: Kolodner 1999 - - Germline - - - 0 - DNA SEQ - - ? - PubMed: Kolodner 1999 healthy controls - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - G>A at 116 - MSH6_000915 - PubMed: Plaschke 2000 - - Germline - - - 0 - DNA SEQ - - ? - PubMed: Plaschke 2000 healthy donors - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Parent #1 g.48010488G>A - G>A at 116 - MSH6_000915 - PubMed: Nicolaides 1996 - - Germline - - - 0 - DNA SEQ - - ? - PubMed: Nicolaides 1996 - ? - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - p.Gly39Glu - MSH6_000915 - PubMed: Landi 2006 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - p.Gly39Glu - MSH6_000915 - PubMed: Berndt 2007 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - p.Gly39Glu - MSH6_000915 polymorphism showing higher risk for malignant urinary bladder neoplasms than non-carriers PubMed: Sanyal 2007 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - p.Gly39Glu - MSH6_000915 identified in a glioblastoma multiforme tumour sample PubMed: Maxwell 2008 - - Somatic - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Verma 1999 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Charames 2000 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Parc 2000 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Peterlongo 2003 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Kim 2004 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Kim 2004 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Vahteristo 2005 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Woods 2005 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Hegde 2005 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Sanchez de Abajo 2005 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Yu 2006 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Hirata 2008 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 associated with colon cancer risk in men PubMed: Campbell 2008 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 no significant association with breast cancer risk PubMed: Smith 2008 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Perez-Cabornero 2009 - - Germline - - - 0 - DNA HD, SEQ - - ? - - - - - Spain - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - - HNPCC - - - F - Brazil - - 0 - - 1 Felipe Silva
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - 116G>A - MSH6_000915 - Kristina Lagerstedt Robinson - - Germline - - - 0 - DNA SEQ - - ? - - - - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - 116G>A - MSH6_000915 - Kristina Lagerstedt Robinson - - Germline - - - 0 - DNA SEQ - - ? - - - - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - 116G>A - MSH6_000915 - Kristina Lagerstedt Robinson - - Germline - - - 0 - DNA SEQ - - ? - - - - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - Het 116G>A (p.G39E). - MSH6_000915 - Desiree du Sart - - Germline - - - 0 - DNA SEQ - - ? - - - - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - 116G>A - MSH6_000915 - Desiree du Sart - - Germline - - - 0 - DNA SEQ - - CRC - - - - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - 3150_3162dup hetero; 116G>A hetero; 2633T>C hetero - MSH6_000915 - Gabriel Capell?í and Ignacio Blanco - - Germline - - - 0 - DNA SEQ, MLPA - - CRC - - - M - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.116g>a p.Gly39Glu Unknown g.48010488G>A - p.[Gly39Glu]+[Gly39Glu] - MSH6_000915 identified in a glioblastoma multiforme tumour sample PubMed: Maxwell 2008 - - Somatic - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.116g>a p.Gly39Glu Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - - HNPCC - - - F - Brazil - - 0 - - 1 Felipe Silva
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - Dx bowel ca 40yrs, IHC absent MSH6. Austin clinicHet for seq variants: 116G>A, 186C>A, 276A>G, 540T>C, 3438+14A>T. - MSH6_000915 - Desiree du Sart - - Germline - - - 0 - DNA ? - - CRC - - - - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - p.Gly39Glu - MSH6_000915 - PubMed: Zidan 2007 - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 Michael Woods
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA PCR, SEQ - - CRC - - - ? - Germany - - 0 - - 1 Peter Propping, Prof. Dr. med.
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA PCR, SEQ - - CRC - - - ? - Germany - - 0 - - 1 Peter Propping, Prof. Dr. med.
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA PCR, SEQ - - CRC - - - ? - Germany - - 0 - - 1 Peter Propping, Prof. Dr. med.
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 MSH6 variants: c.116G>A (p.G39E) het.MSH2 seq reported 10.10.07. Seq variants: c.211+9C>G. c.1661+6T>C and c.2006-6T>C (HOM). NOT prev reported and clinical sig uncertain c.2634+12T>C (Het).H1/H2 MLPA rep 20/12/08 Desiree du Sart - - Germline - - - 0 - DNA ? - - ? - - - - - - - - 0 - - 1 INSiGHT group
?/. 1 c.116G>A VUS r.(?) p.(Gly39Glu) Unknown g.48010488G>A - MSH2 seq reported 23/01/09. mlpa reported 23/01/09.Hom:211+9C>G, 1661+12G>A, het 2006-6T>CMSH6 polys:116G>A, 3306T>A - MSH6_000915 - Desiree du Sart - - Germline - - - 0 - DNA ? - - ? - - - ? - - - - 0 - - 1 INSiGHT group
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - Paternal grandmother (60, dec.) had Breast Cancer at 55 years old; Paternal aunt (67) had Ovarian Cancer at 61 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 ? - - Maternal aunt (61) had Breast Cancer at 50 years old; Paternal grandmother (62, dec.) had Lymphoma at 55 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - Maternal grandmother (90 or older, dec.) had Liver at 89 years old; Sister (72, dec.) had Breast Cancer at 68 years old; Maternal aunt (60, dec.) had Lung at 55 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - no family history F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - Maternal aunt (48, dec.) had Breast Cancer at 42 years old; Maternal aunt (48, dec.) had Ovarian Cancer at 42 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 cancer, breast - - no family history F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 ? - - Paternal aunt (66) had Breast Cancer at 35 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 ? - - Sister (15, dec.) had Leukemia at 14 years old; Maternal grandfather (60, dec.) had Bone Cancer at 59 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2017-01-01 ? - - no family history M - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2017-01-01 ? - - no family history M - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2017-01-01 ? - - no family history M - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2017-01-01 cancer, breast - - Mother (58, dec.) had Ovarian Cancer at 58 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 ? - - Mother (64) had Breast Cancer at 30 years old; Maternal grandfather (63, dec.) had Lung at 61 years old M - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 ? - - Maternal grandfather (90 or older, dec.) had Melanoma at 70 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 CRC - - no family history M - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2017-01-01 ? - - Mother (87) had Merkel Cell Carcinoma at 64 years old; Maternal uncle (84) had Prostate Cancer at 77 years old; Maternal uncle (72, dec.) had Lung at 72 years old; Paternal grandfather (80, dec.) had Lung at 79 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - Mother (66) had Breast Cancer at 30 years old; Maternal aunt (58, dec.) had Colon at 56 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 ? - - no family history F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 ? - - Maternal grandmother (90 or older, dec.) had Colorectal Cancer at 85 years old; Paternal grandfather (87) had Lymphoma at 80 years old M - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2017-01-01 ? - - Father (76, dec.) had Liver at 65 years old M - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - no family history F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 cancer, breast - - Maternal aunt (70, dec.) had Breast Cancer at 50 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2017-01-01 cancer, breast - - Sister (42, dec.) had Breast Cancer at 42 years old; Maternal aunt (90 or older, dec.) had Breast Cancer at 55 years old; Maternal grandfather (86, dec.) had Lung Cancer at 70 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - Maternal grandmother (89) had Cervical at 71 years old; Maternal grandfather (88) had Prostate at 65 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - Maternal aunt (63) had Breast Cancer at 40 years old; Maternal grandmother (89) had Breast Cancer at 80 years old; Father (50, dec.) had Brain Cancer at 49 years old M - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2015-01-01 ? - - Mother (76) had Breast Cancer at 52 years old; Mother (76) had Bone Marrow at 70 years old; Father (79) had Prostate at 68 years old F - - - - 0 - - 1 Jack Ji
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ - screen date 2016-01-01 cancer, breast - - Mother (1) had Breast Cancer at 28 years old; Sister (41) had Breast Cancer at 40 years old F - - - - 0 - - 1 Jack Ji
-/. - c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A - - - MSH6_000915 - PubMed: Thodi 2010 - - Germline - - - 0 - DNA ? - - ? - PubMed: Thodi 2010 - - - Greece - - 0 - - 2 InSiGHT - John-Paul Plazzer
-/. - c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A g.47783349G>A - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ-NG - - cancer, colon contributed by Dept. of Dr Vaccaro - - - - Argentina - - 0 - - 1 Carlos Vaccaro
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A g.47783349G>A - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ, SEQ-NG - gene panel cancer, colon - - - - - Argentina - - 0 - - 1 Maximiliano Zeballos
-/. 1 c.116G>A benign r.(?) p.(Gly39Glu) Unknown g.48010488G>A g.47783349G>A - - MSH6_000915 - - - - Germline - - - 0 - DNA SEQ, SEQ-NG - gene panel cancer, colon - - - - - Argentina Spain - 0 - - 1 Maximiliano Zeballos
Legend