The APC gene homepage

General information
Gene symbol APC
Gene name adenomatous polyposis coli
Chromosome 5
Chromosomal band q21-q22
Imprinted Unknown
Genomic reference LRG_130
Transcript reference NM_000038.5
Associated with diseases CRC, FAP-1, HDD, polyposis, cancer, gastric (Neoplasm of stomach), Hepatocellular carcinoma
Citation reference(s) -
Curators (1) Johan T. den Dunnen
Total number of public variants reported 227
Unique public DNA variants reported 22
Individuals with public variants 35
Hidden variants 72
Date created November 30, -0001
Date last updated September 28, 2016
Version APC:160928

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
External URL List of LSDBs for this gene
The reference LOVD for this gene, if available
HGNC HGNC:583
Entrez Gene 324
PubMed articles APC
OMIM - Gene 611731
OMIM - Diseases CRC (cancer, colorectal (CRC))
FAP-1 (adenomatous polyposis, familial, type 1 (FAP-1, Gardner syndrome))
HDD (desmoid disease, hereditary (HDD))
cancer, gastric (Neoplasm of stomach)
Hepatocellular carcinoma


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00010045 5 transcript variant 3 NM_000038.5 NP_000029.2 227