The BRCA2 gene homepage

General information
Gene symbol BRCA2
Gene name breast cancer 2, early onset
Chromosome 13
Chromosomal band q12-q13
Imprinted Unknown
Genomic reference LRG_293
Transcript reference NM_000059.3
Associated with diseases BROVCA-2, FANCD-1, GLM-3, MDB, PNCA-2, WT-1, cancer, breast, cancer, breast, familial, cancer, prostate
Citation reference(s) -
Curators (1) Johan T. den Dunnen
Total number of public variants reported 286
Unique public DNA variants reported 37
Individuals with public variants 35
Hidden variants 25
Date created November 30, -0001
Date last updated September 28, 2016
Version BRCA2:160928

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
External URL List of LSDBs for this gene
The reference LOVD for this gene, if available
HGNC HGNC:1101
Entrez Gene 675
PubMed articles BRCA2
OMIM - Gene 600185
OMIM - Diseases BROVCA-2 (cancer, breast-ovarian, familial, susceptibility to, type 2 (BROVCA-2))
FANCD-1 (Fanconi anemia, complementation group D1 (FANCD-1))
GLM-3 (glioma, susceptibility, type 3 (GLM-3))
MDB (medulloblastoma (MDB))
PNCA-2 (cancer, pancreatic, susceptibility to, type 2 (PNCA-2))
WT-1 (Wilms tumor, type 1, somatic (WT-1, nephroblastoma))
cancer, breast, familial
cancer, prostate


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00010304 13 breast cancer 2, early onset NM_000059.3 NP_000050.2 286