The COMT gene homepage

General information
Gene symbol COMT
Gene name catechol-O-methyltransferase
Chromosome 22
Chromosomal band q11.21
Imprinted Unknown
Genomic reference NG_011526.1
Transcript reference NM_000754.3, NM_001135161.1, NM_001135162.1, NM_007310.2, XM_005261229.1
Associated with diseases PAND-1, SCZD
Citation reference(s) -
Curators (1) Johan T. den Dunnen
Total number of public variants reported 268
Unique public DNA variants reported 24
Individuals with public variants 35
Hidden variants 84
Date created November 30, -0001
Date last updated September 28, 2016
Version COMT:160928

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
External URL List of LSDBs for this gene
The reference LOVD for this gene, if available
HGNC HGNC:2228
Entrez Gene 1312
PubMed articles COMT
OMIM - Gene 116790
OMIM - Diseases PAND-1 (panic disorder 1 (PAND-1))
SCZD (schizophrenia (SCZD))


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00010907 22 transcript variant 4 NM_007310.2 NP_009294.1 267
00010904 22 transcript variant 1 NM_000754.3 NP_000745.1 252
00010905 22 transcript variant 2 NM_001135161.1 NP_001128633.1 251
00010906 22 transcript variant 3 NM_001135162.1 NP_001128634.1 251
00042385 22 transcript variant X1 XM_005261229.1 XP_005261286.1 -