The APOE gene homepage

General information
Gene symbol APOE
Gene name apolipoprotein E
Chromosome 19
Chromosomal band q13.31
Imprinted Unknown
Genomic reference NC_000019.9
Transcript reference NM_000041.2
Exon/intron information NM_000041.2 exon/intron table
Associated with diseases AD-2, AD-4, ARMD-1, Lipoprotein glomerulopathy, Sea-blue histiocyte syndrome
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 240
Unique public DNA variants reported 91
Individuals with public variants 330
Hidden variants 10
Date created May 03, 2013
Date last updated September 17, 2021
Version APOE:210917

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_000041.2.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
HGNC 613
Entrez Gene 348
PubMed articles APOE
OMIM - Gene 107741
OMIM - Diseases AD-2 (Alzheimer disease, type 2 (AD-2))
AD-4 (Alzheimer disease, type 4 (AD-4))
ARMD-1 (macular degeneration, age-related, type 1 (ARMD-1))
Lipoprotein glomerulopathy
Sea-blue histiocyte syndrome
GeneCards APOE
GeneTests APOE
Orphanet APOE

Active transcripts




NCBI ID     

NCBI Protein ID     

00002703 19 apolipoprotein E NM_000041.2 NP_000032.1 240

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