CYP2C19 gene homepage

General information
Gene symbol CYP2C19
Gene name cytochrome P450, family 2, subfamily C, polypeptide 19
Chromosome 10
Chromosomal band q24
Imprinted Unknown
Genomic reference NG_008384.2
Transcript reference NM_000769.1
Exon/intron information NM_000769.1 exon/intron table
Associated with diseases DMB-CYP2C19, DMB-p
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) LOVD-team, but with Curator vacancy
Total number of public variants reported 236
Unique public DNA variants reported 42
Individuals with public variants 153
Hidden variants 32
Download all this gene's data Download all data
Notes CYP2C19 reference haplotypes in this database.
Download the current CYP2C19 reference haplotype list (ver.2015-10-08).
Haplotypes are assigned by the Human Cytochrome P450 (CYP) Allele Nomenclature Committee; current CYP2C19 list
Date created April 29, 2010
Date last updated December 19, 2018
Version CYP2C19:181219

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_000769.1.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
External URL Orphanet
Human Cytochrome P450 (CYP) Allele Nomenclature Committee
PharmGKB CYP2C19
HGNC 2621
Entrez Gene 1557
PubMed articles CYP2C19
OMIM - Gene 124020
OMIM - Diseases DMB-CYP2C19 (drug metabolism, poor)
GeneCards CYP2C19
GeneTests CYP2C19

Active transcripts




NCBI ID     

NCBI Protein ID     

00006002 10 cytochrome P450, family 2, subfamily C, polypeptide 19 NM_000769.1 NP_000760.1 236

Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective curator(s). Any unauthorised use, copying, storage or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2010-2019. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.