The CYP2C19 gene homepage

General information
Gene symbol CYP2C19
Gene name cytochrome P450, family 2, subfamily C, polypeptide 19
Chromosome 10
Chromosomal band q24
Imprinted Unknown
Genomic reference NG_008384.2
Transcript reference NM_000769.1
Exon/intron information NM_000769.1 exon/intron table
Associated with diseases DMBCYP2C19, DMBp
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 243
Unique public DNA variants reported 44
Individuals with public variants 247
Hidden variants 32
Download all this gene's data Download all data
Notes CYP2C19 reference haplotypes in this database.
Download the current CYP2C19 reference haplotype list (ver.2015-10-08).
Haplotypes are assigned by the Human Cytochrome P450 (CYP) Allele Nomenclature Committee; current CYP2C19 list
Date created April 29, 2010
Date last updated March 21, 2022
Version CYP2C19:220321

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_000769.1.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
External URL Human Cytochrome P450 (CYP) Allele Nomenclature Committee
PharmGKB CYP2C19
HGNC 2621
Entrez Gene 1557
PubMed articles CYP2C19
OMIM - Gene 124020
OMIM - Diseases DMBCYP2C19 (drug metabolism, poor)
GeneCards CYP2C19
GeneTests CYP2C19
Orphanet CYP2C19

Active transcripts




NCBI ID     

NCBI Protein ID     

00006002 10 cytochrome P450, family 2, subfamily C, polypeptide 19 NM_000769.1 NP_000760.1 243

Copyright & disclaimer
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