CYP2C19 gene homepage

General information
Gene symbol CYP2C19
Gene name cytochrome P450, family 2, subfamily C, polypeptide 19
Chromosome 10
Chromosomal band q24
Imprinted Unknown
Genomic reference NG_008384.2
Transcript reference NM_000769.1
Exon/intron information NM_000769.1 exon/intron table
Associated with diseases DMB-CYP2C19, DMB-p
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) LOVD-team, but with Curator vacancy
Total number of public variants reported 236
Unique public DNA variants reported 42
Individuals with public variants 153
Hidden variants 32
Download all this gene's data Download all data
Notes CYP2C19 reference haplotypes in this database.
Download the current CYP2C19 reference haplotype list (ver.2015-10-08).
Haplotypes are assigned by the Human Cytochrome P450 (CYP) Allele Nomenclature Committee; current CYP2C19 list
Date created April 29, 2010
Date last updated December 19, 2018
Version CYP2C19:181219

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_000769.1.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL http://www.LOVD.nl/CYP2C19
External URL Orphanet
Human Cytochrome P450 (CYP) Allele Nomenclature Committee
PharmGKB CYP2C19
HGNC 2621
Entrez Gene 1557
PubMed articles CYP2C19
OMIM - Gene 124020
OMIM - Diseases DMB-CYP2C19 (drug metabolism, poor)
HGMD CYP2C19
GeneCards CYP2C19
GeneTests CYP2C19


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00006002 10 cytochrome P450, family 2, subfamily C, polypeptide 19 NM_000769.1 NP_000760.1 236


Copyright & disclaimer
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