The DPYD gene homepage

General information
Gene symbol DPYD
Gene name dihydropyrimidine dehydrogenase
Chromosome 1
Chromosomal band p22
Imprinted Not imprinted
Genomic reference LRG_722
Transcript reference NM_000110.3
Exon/intron information NM_000110.3 exon/intron table
Associated with diseases DMBp, DPDD, ID
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 209
Unique public DNA variants reported 68
Individuals with public variants 578
Hidden variants 11
Notes The establishment of this gene variant database (LSDB) was supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement nÂș 200754 - the GEN2PHEN project.
DPYD reference haplotypes
Date created April 05, 2011
Date last updated May 09, 2022
Version DPYD:220509

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_000110.3.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
External URL PharmGKB
HGNC 3012
Entrez Gene 1806
PubMed articles DPYD
OMIM - Gene 612779
OMIM - Diseases DPDD (dihydropyrimidine dehydrogenase deficiency (DPDD))
GeneCards DPYD
GeneTests DPYD
Orphanet DPYD

Active transcripts




NCBI ID     

NCBI Protein ID     

00000078 1 dihydropyrimidine dehydrogenase, transcript variant 1 NM_000110.3 NP_000101.2 209

Copyright & disclaimer
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