The FGB gene homepage

General information
Gene symbol FGB
Gene name fibrinogen beta chain
Chromosome 4
Chromosomal band q31.3
Imprinted Unknown
Genomic reference NG_008833.1
Transcript reference NM_005141.4
Exon/intron information NM_005141.4 exon/intron table
Associated with diseases afibrinogenemia, congenital, Dysfibrinogenemia, congenital
Citation reference(s) PubMed: McVey et al., 2020
Refseq URL Genomic reference sequence
Curators (1) Daniel J Hampshire
Total number of public variants reported 15
Unique public DNA variants reported 12
Individuals with public variants 5
Hidden variants 1
Notes This version of the database is under construction. Please refer to the EAHAD Coagulation Factor Variant Databases for current listings.
Date created May 03, 2013
Date last updated February 08, 2021
Version FGB:210208

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_005141.4.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL https://www.LOVD.nl/FGB
External URL EAHAD Coagulation Factor Variant Databases
HGNC 3662
Entrez Gene 2244
PubMed articles FGB
OMIM - Gene 134830
OMIM - Diseases afibrinogenemia, congenital
Dysfibrinogenemia, congenital
HGMD FGB
GeneCards FGB
GeneTests FGB
Orphanet FGB


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00007898 4 transcript variant 1 NM_005141.4 NP_005132.2 15


Copyright & disclaimer
The European Association for Haemophilia and Allied Disorders (EAHAD) Coagulation Factor Mutation Databases are maintained and provided as a public service for the clinical, diagnostic and coagulation factor research communities. All individuals accessing and using the information contained in these mutation databases managed by EAHAD explicitly agree to abide by the database policy.

This version of the database is under construction. Please refer to the EAHAD Coagulation Factor Variant Databases for current listings.