The FREM2 gene homepage

General information
Gene symbol FREM2
Gene name FRAS1 related extracellular matrix protein 2
Chromosome 13
Chromosomal band q13.3
Imprinted Unknown
Genomic reference NG_008125.2
Transcript reference NM_207361.4
Exon/intron information NM_207361.4 exon/intron table
Associated with diseases FRASRS1, FRASRS2, ID
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 272
Unique public DNA variants reported 239
Individuals with public variants 105
Hidden variants 35
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created May 03, 2013
Date last updated November 01, 2022
Version FREM2:221101

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_207361.4.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
HGNC 25396
Entrez Gene 341640
PubMed articles FREM2
OMIM - Gene 608945
OMIM - Diseases FRASRS1 (Fraser syndrome)
FRASRS2 (Fraser syndrome 2)
GeneCards FREM2
GeneTests FREM2
Orphanet FREM2

Active transcripts




NCBI ID     

NCBI Protein ID     

00008132 13 FRAS1 related extracellular matrix protein 2 NM_207361.4 NP_997244.3 272

Copyright & disclaimer
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