IL12B gene homepage

General information
Gene symbol IL12B
Gene name interleukin 12B
Chromosome 5
Chromosomal band q33.3
Imprinted Unknown
Genomic reference LRG_71
Transcript reference NM_002187.2
Exon/intron information NM_002187.2 exon/intron table
Associated with diseases IMD-29
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Esther van de Vosse
Total number of public variants reported 48
Unique public DNA variants reported 14
Individuals with public variants 873
Hidden variants 0
Notes Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created April 29, 2010
Date last updated July 03, 2019
Version IL12B:190703

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_002187.2.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL http://www.LOVD.nl/IL12B
External URL Orphanet
HGNC 5970
Entrez Gene 3593
PubMed articles IL12B
OMIM - Gene 161561
OMIM - Diseases IMD-29 (immunodeficiency, type 29, mycobacteriosis (IMD-29))
HGMD IL12B
GeneCards IL12B
GeneTests IL12B


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00024157 5 interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) NM_002187.2 NP_002178.2 48


Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective curator(s). Any unauthorised use, copying, storage or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2010-2019. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.