The LRP4 gene homepage

General information
Gene symbol LRP4
Gene name low density lipoprotein receptor-related protein 4
Chromosome 11
Chromosomal band p11.2
Imprinted Unknown
Genomic reference NG_021394.1
Transcript reference NM_002334.3
Exon/intron information NM_002334.3 exon/intron table
Associated with diseases CLSS, CMS-17, SOST, SOST-2
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 61
Unique public DNA variants reported 47
Individuals with public variants 281
Hidden variants 4
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created June 01, 2010
Date last updated February 08, 2021
Version LRP4:210208

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_002334.3.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
HGNC 6696
Entrez Gene 4038
PubMed articles LRP4
OMIM - Gene 604270
OMIM - Diseases CLSS (syndrome, Cenani-Lenz syndactyly (CLSS))
CMS-17 (myasthenic syndrome?, congenital, type 17 (CMS-17))
SOST-2 (sclerosteosis, type 2 (SOST-2))
GeneCards LRP4
GeneTests LRP4
Orphanet LRP4

Active transcripts




NCBI ID     

NCBI Protein ID     

00023984 11 low density lipoprotein receptor-related protein 4 NM_002334.3 NP_002325.2 61

Copyright & disclaimer
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We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.