LRRK2 gene homepage

General information
Gene symbol LRRK2
Gene name leucine-rich repeat kinase 2
Chromosome 12
Chromosomal band q12
Imprinted Unknown
Genomic reference NG_011709.1
Transcript reference NM_198578.3
Exon/intron information NM_198578.3 exon/intron table
Associated with diseases PARK-8
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) LOVD-team, but with Curator vacancy
Total number of public variants reported 80
Unique public DNA variants reported 51
Individuals with public variants 1
Hidden variants 0
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created March 27, 2008
Date last updated March 27, 2016
Version LRRK2:160327

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_198578.3.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL http://www.LOVD.nl/LRRK2
External URL Orphanet
HGNC 18618
Entrez Gene 120892
PubMed articles LRRK2
OMIM - Gene 609007
OMIM - Diseases PARK-8 (Parkinson disease, type 8, autosomal dominant (PARK-8))
HGMD LRRK2
GeneCards LRRK2
GeneTests LRRK2


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00011511 12 leucine-rich repeat kinase 2 NM_198578.3 NP_940980.3 80


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