The NFIX gene homepage

General information
Gene symbol NFIX
Gene name nuclear factor I/X (CCAAT-binding transcription factor)
Chromosome 19
Chromosomal band p13.3
Imprinted Unknown
Genomic reference NG_032925.2
Transcript reference NM_001271043.1, NM_002501.2
Exon/intron information NM_001271043.1 exon/intron table
Associated with diseases ID, MRSHSS, SOTOS, SOTOS-2
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 108
Unique public DNA variants reported 79
Individuals with public variants 85
Hidden variants 22
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created November 19, 2012
Date last updated February 08, 2021
Version NFIX:210208

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_001271043.1.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
HGNC 7788
Entrez Gene 4784
PubMed articles NFIX
OMIM - Gene 164005
OMIM - Diseases MRSHSS (Marshall-Smith syndrome (MRSHSS))
SOTOS-2 (Sotos syndrome, type 2 (SOTOS-2))
GeneCards NFIX
GeneTests NFIX
Orphanet NFIX

Active transcripts




NCBI ID     

NCBI Protein ID     

00001767 19 transcript variant 1 NM_001271043.1 NP_001257972.1 106
00025274 19 transcript variant 2 NM_002501.2 NP_002492.2 81

Copyright & disclaimer
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We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.