The SLX4 gene homepage

A Fanconi anemia mutation database.
General information
Gene symbol SLX4
Gene name SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Chromosome 16
Chromosomal band p13.3
Imprinted Unknown
Genomic reference NG_028123.1
Transcript reference NM_032444.2
Exon/intron information NM_032444.2 exon/intron table
Associated with diseases FANCP
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 190
Unique public DNA variants reported 144
Individuals with public variants 1469
Hidden variants 11
Download all this gene's data Download all data
Notes Reference sequence NG_028123.1 is identical to LRG_503
Variants associated with Fanconi anemia.
We gratefully acknowledge the efforts of Arleen Auerbach curating the variant linked to Fanconi Anemia (until end 2019).
Date created February 07, 2011
Date last updated October 13, 2021
Version SLX4:211013

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_032444.2.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL https://www.LOVD.nl/SLX4
External URL Fanconi anemia mutation databases homepage (Rockefeller University)
HGNC 23845
Entrez Gene 84464
PubMed articles SLX4
OMIM - Gene 613278
OMIM - Diseases FANCP (Fanconi anemia, complementation group P (FANCP))
HGMD SLX4
GeneCards SLX4
GeneTests SLX4
Orphanet SLX4


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00019403 16 SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) NM_032444.2 NP_115820.2 190


Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective submitter(s) and curator(s) of the individual records. Individual data entries may indicate which data license applies to that specific record. When no license is listed, no permissions are granted. Any unauthorized use, copying, storage, or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2011-2021. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising from any inaccuracies or omissions. Individuals, organizations, and companies that use this database do so on the understanding that no liability whatsoever, either direct or indirect, shall rest upon the data submitter(s), curator(s), or any of their employees or agents for the effects of any product, process, or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.