The SOS1 gene homepage

General information
Gene symbol SOS1
Gene name son of sevenless homolog 1 (Drosophila)
Chromosome 2
Chromosomal band p21
Imprinted Unknown
Genomic reference NG_007530.1
Transcript reference NM_005633.3
Exon/intron information NM_005633.3 exon/intron table
Associated with diseases GINGF1, ID, NS, NS4
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Global Variome, with Curator vacancy
Total number of public variants reported 304
Unique public DNA variants reported 175
Individuals with public variants 271
Hidden variants 11
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created April 29, 2010
Date last updated July 07, 2023
Version SOS1:230707

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_005633.3.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL
HGNC 11187
Entrez Gene 6654
PubMed articles SOS1
OMIM - Gene 182530
OMIM - Diseases GINGF1 (fibromatosis, gingival, type 1)
NS4 (Noonan syndrome, type 4 (NS-4))
GeneCards SOS1
GeneTests SOS1
Orphanet SOS1

Active transcripts




NCBI ID     

NCBI Protein ID     

00020028 2 son of sevenless homolog 1 (Drosophila) NM_005633.3 NP_005624.2 304

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