The SPARC gene homepage


Osteogenesis Imperfecta Variant Database
General information
Gene symbol SPARC
Gene name secreted protein acidic and cysteine rich
Chromosome 5
Chromosomal band q33.1
Imprinted Unknown
Genomic reference NC_000005.9
Transcript reference NM_003118.3
Exon/intron information NM_003118.3 exon/intron table
Associated with diseases OI, OI17
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (3) Raymond Dalgleish, Gerard Pals, and Sonna Stolk
Total number of public variants reported 6
Unique public DNA variants reported 6
Individuals with public variants 6
Hidden variants 1
Download all this gene's data Download all data
Notes Establishment of the database was supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement No 200754 - the GEN2PHEN project.
This database is supported by , Osteogenesis Imperfecta Federation Europe (OIFE)
Date created May 03, 2013
Date last updated May 11, 2021
Version SPARC:210511

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_003118.3.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL https://www.LOVD.nl/SPARC
External URL Osteogenesis Imperfecta & Ehlers-Danlos syndrome variant databases
Osteogenesis Imperfecta Federation Europe (OIFE)
HGNC 11219
Entrez Gene 6678
PubMed articles SPARC
OMIM - Gene 182120
OMIM - Diseases OI17 (osteogenesis imperfecta, type XVII (OI17))
HGMD SPARC
GeneCards SPARC
GeneTests SPARC
Orphanet SPARC


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00020100 5 secreted protein, acidic, cysteine-rich (osteonectin) NM_003118.3 NP_003109.1 6


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