The TEK gene homepage


This database is one of the "Vascular anomalies and lymphedema" gene variant databases.
General information
Gene symbol TEK
Gene name TEK tyrosine kinase, endothelial
Chromosome 9
Chromosomal band p21
Imprinted Unknown
Genomic reference NG_011828.1
Transcript reference NM_000459.3
Exon/intron information NM_000459.3 exon/intron table
Associated with diseases GLC3E, VMCM
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Antonella Mendola
Total number of public variants reported 220
Unique public DNA variants reported 76
Individuals with public variants 136
Hidden variants 0
Download all this gene's data Download all data
Notes This database is one of the "Vascular anomalies and lymphedema" gene variant databases, curated by the Laboratory of Human Molecular Genetics, de Duve Institute, Brussels (Belgium).
Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created December 23, 2009
Date last updated May 09, 2022
Version TEK:220509

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_000459.3.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL https://www.LOVD.nl/TEK
HGNC 11724
Entrez Gene 7010
PubMed articles TEK
OMIM - Gene 600221
OMIM - Diseases GLC3E (Glaucoma 3, primary congenital, E)
VMCM (venous malformations, multiple cutaneous and mucosal (VMCM))
HGMD TEK
GeneCards TEK
GeneTests TEK
Orphanet TEK


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00000981 9 TEK tyrosine kinase, endothelial NM_000459.3 NP_000450.2 220


Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective submitter(s) and curator(s) of the individual records. Individual data entries may indicate which data license applies to that specific record. When no license is listed, no permissions are granted. Any unauthorized use, copying, storage, or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2009-2022. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising from any inaccuracies or omissions. Individuals, organizations, and companies that use this database do so on the understanding that no liability whatsoever, either direct or indirect, shall rest upon the data submitter(s), curator(s), or any of their employees or agents for the effects of any product, process, or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.