TP63 gene homepage

General information
Gene symbol TP63
Gene name tumor protein p63
Chromosome 3
Chromosomal band q27-q29
Imprinted Unknown
Genomic reference NG_007550.1
Transcript reference NM_001114979.1, NM_003722.4
Exon/intron information NM_003722.4 exon/intron table
Associated with diseases ADULT, AEC, EEC, EEC-3, LMS, OFC-8, RHS, SHFM-4
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (1) Paul van der Zwaag
Total number of public variants reported 111
Unique public DNA variants reported 97
Individuals with public variants 39
Hidden variants 2
Download all this gene's data Download all data
Notes Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland.
Date created February 25, 2009
Date last updated May 23, 2019
Version TP63:190523

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
Reading frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes. Active for: NM_003722.4.
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL https://www.LOVD.nl/TP63
External URL Orphanet
ARVD/C Genetic Variants Database
HGNC 15979
Entrez Gene 8626
PubMed articles TP63
OMIM - Gene 603273
OMIM - Diseases ADULT (syndrome, ADULT (ADULT))
AEC (Hay-Wells)
EEC-3 (ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome, type 3 (EEC-3))
LMS (syndrome, Limb-mammary (LMS))
OFC-8 (orofacial cleft, type 8 (OFC-8))
RHS (syndrome, Rapp-Hodgkin (RHS))
SHFM-4 (split-hand/foot malformation, type 4 (SHFM-4))
HGMD TP63
GeneCards TP63
GeneTests TP63


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00021671 3 transcript variant 1 NM_003722.4 NP_003713.3 111
00025349 3 transcript variant 3 NM_001114979.1 NP_001108451.1 88


Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective curator(s). Any unauthorised use, copying, storage or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2009-2019. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

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