TPM2 gene homepage

This database is one of the gene variant databases from the Leiden Muscular Dystrophy pages
General information
Gene symbol TPM2
Gene name tropomyosin 2 (beta)
Chromosome 9
Chromosomal band p13
Imprinted Unknown
Genomic reference NG_011620.1
Transcript reference NM_003289.3, NM_213674.1
Associated with diseases CFTD, DA-1A, DA-2B, NEM-4
Citation reference(s) -
Refseq URL Genomic reference sequence
Curators (2) Johan den Dunnen and Tom Winder
Total number of public variants reported 101
Unique public DNA variants reported 61
Individuals with public variants 393
Hidden variants 0
Download all this gene's data Download all data
Notes This database is one of the gene variant databases from the:
Date created September 24, 2008
Date last updated April 29, 2019
Version TPM2:190429

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL https://www.LOVD.nl/TPM2
HGNC 12011
Entrez Gene 7169
PubMed articles TPM2
OMIM - Gene 190990
OMIM - Diseases CFTD (myopathy, congenital, with fiber type disproportion (CFTD))
DA-1A (arthrogryposis multiplex congenita, distal, type 1A (DA-1A))
DA-2B (arthrogryposis, distal, type 2B (DA-2B))
NEM-4 (myopathy, nemaline, type 4 (NEM-4))
HGMD TPM2
GeneCards TPM2
GeneTests TPM2


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00025394 9 transcript variant 2 NM_213674.1 NP_998839.1 101
00021691 9 transcript variant 1 NM_003289.3 NP_003280.2 100


Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective curator(s). Any unauthorised use, copying, storage or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2008-2019. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.