All individuals with variants in gene TERC

Legend

Please note that a short description of a certain column can be displayed when you move your mouse cursor over the column's header and hold it still. Below, a more detailed description is shown per column.

ID_report: ID of the individual that can be publically shared, e.g. as listed in a publication

Reference: reference to publication describing the individual/family, possibly giving more phenotypic details than listed in this database entry, incl. link to PubMed or other source, e.g. "den Dunnen ASHG2003 P2346"

Remarks: remarks about the individual

Gender: gender individual
All options:

? = unknown
- = not applicable
F = female
M = male
rF = raised as female
rM = raised as male

Consanguinity: indicates whether the parents are related (consanguineous), not related (non-consanguineous) or whether consanguinity is not known (unknown)
All options:

no = non-consanguineous parents
yes = consanguineous parents
likely = consanguinity likely
? = unknown
- = not applicable

Country: where (country) does the individual live/recently came from. Give additional details (population, specific sub-group) and when parents come from different countries in "Population". Belgium = individual lives in/recently came from Belgium, (France) = reported by laboratory in France, individual's country of origin not sure
All options:

? (unknown)
- (not applicable)
Afghanistan
(Afghanistan)
Albania
(Albania)
Algeria
(Algeria)
American Samoa
(American Samoa)
Andorra
(Andorra)
Angola
(Angola)
Anguilla
(Anguilla)
Antarctica
(Antarctica)
Antigua and Barbuda
(Antigua and Barbuda)
Argentina
(Argentina)
Armenia
(Armenia)
Aruba
(Aruba)
Australia
(Australia)
Austria
(Austria)
Azerbaijan
(Azerbaijan)
Bahamas
(Bahamas)
Bahrain
(Bahrain)
Bangladesh
(Bangladesh)
Barbados
(Barbados)
Belarus
(Belarus)
Belgium
(Belgium)
Belize
(Belize)
Benin
(Benin)
Bermuda
(Bermuda)
Bhutan
(Bhutan)
Bolivia
(Bolivia)
Bosnia and Herzegovina
(Bosnia and Herzegovina)
Botswana
(Botswana)
Bouvet Island
(Bouvet Island)
Brazil
(Brazil)
British Indian Ocean Territory
(British Indian Ocean Territory)
Brunei Darussalam
(Brunei Darussalam)
Bulgaria
(Bulgaria)
Burkina Faso
(Burkina Faso)
Burundi
(Burundi)
Cambodia
(Cambodia)
Cameroon
(Cameroon)
Canada
(Canada)
Cape Verde
(Cape Verde)
Cayman Islands
(Cayman Islands)
Central African Republic
(Central African Republic)
Central Europe
Chad
(Chad)
Chile
(Chile)
China
(China)
Christmas Island
(Christmas Island)
Cocos (Keeling Islands)
(Cocos (Keeling Islands))
Colombia
(Colombia)
Comoros
(Comoros)
Congo
(Congo)
Cook Islands
(Cook Islands)
Costa Rica
(Costa Rica)
Cote D'Ivoire (Ivory Coast)
(Cote D'Ivoire (Ivory Coast))
Croatia (Hrvatska)
(Croatia (Hrvatska))
Cuba
(Cuba)
Cyprus
(Cyprus)
Czech Republic
(Czech Republic)
Denmark
(Denmark)
Djibouti
(Djibouti)
Dominica
(Dominica)
Dominican Republic
(Dominican Republic)
East Timor
(East Timor)
Ecuador
(Ecuador)
Egypt
(Egypt)
El Salvador
(El Salvador)
England
(England)
Equatorial Guinea
(Equatorial Guinea)
Eritrea
(Eritrea)
Estonia
(Estonia)
Ethiopia
(Ethiopia)
Falkland Islands (Malvinas)
(Falkland Islands (Malvinas))
Faroe Islands
(Faroe Islands)
Fiji
(Fiji)
Finland
(Finland)
France
(France)
Gabon
(Gabon)
Gambia
(Gambia)
Georgia
(Georgia)
Germany
(Germany)
Ghana
(Ghana)
Gibraltar
(Gibraltar)
Greece
(Greece)
Greenland
(Greenland)
Grenada
(Grenada)
Guadeloupe
(Guadeloupe)
Guam
(Guam)
Guatemala
(Guatemala)
Guiana, French
(Guiana, French)
Guinea
(Guinea)
Guinea-Bissau
(Guinea-Bissau)
Guyana
(Guyana)
Haiti
(Haiti)
Heard and McDonald Islands
(Heard and McDonald Islands)
Honduras
(Honduras)
Hong Kong
(Hong Kong)
Hungary
(Hungary)
Iceland
(Iceland)
India
(India)
Indonesia
(Indonesia)
Iran
(Iran)
Iraq
(Iraq)
Ireland
(Ireland)
Israel
(Israel)
Italy
(Italy)
Jamaica
(Jamaica)
Japan
(Japan)
Jordan
(Jordan)
Kazakhstan
(Kazakhstan)
Kenya
(Kenya)
Kiribati
(Kiribati)
Korea
(Korea)
Korea, North (People's Republic)
(Korea, North (People's Republic))
Korea, South (Republic)
(Korea, South (Republic))
Kosovo
(Kosovo)
Kuwait
(Kuwait)
Kyrgyzstan (Kyrgyz Republic)
(Kyrgyzstan (Kyrgyz Republic))
Laos
(Laos)
Latvia
(Latvia)
Lebanon
(Lebanon)
Lesotho
(Lesotho)
Liberia
(Liberia)
Libya
(Libya)
Liechtenstein
(Liechtenstein)
Lithuania
(Lithuania)
Luxembourg
(Luxembourg)
Macau
(Macau)
Macedonia
(Macedonia)
Madagascar
(Madagascar)
Malawi
(Malawi)
Malaysia
(Malaysia)
Maldives
(Maldives)
Mali
(Mali)
Mallorca
(Mallorca)
Malta
(Malta)
Marshall Islands
(Marshall Islands)
Martinique
(Martinique)
Mauritania
(Mauritania)
Mauritius
(Mauritius)
Mayotte
(Mayotte)
Mexico
(Mexico)
Micronesia
(Micronesia)
Moldova
(Moldova)
Monaco
(Monaco)
Mongolia
(Mongolia)
Montserrat
(Montserrat)
Morocco
(Morocco)
Mozambique
(Mozambique)
Myanmar
(Myanmar)
Namibia
(Namibia)
Nauru
(Nauru)
Nepal
(Nepal)
Netherlands
(Netherlands)
Netherlands Antilles
(Netherlands Antilles)
Neutral Zone (Saudia Arabia/Iraq)
(Neutral Zone (Saudia Arabia/Iraq))
New Caledonia
(New Caledonia)
New Zealand
(New Zealand)
Nicaragua
(Nicaragua)
Niger
(Niger)
Nigeria
(Nigeria)
Niue
(Niue)
Norfolk Island
(Norfolk Island)
Northern Ireland
(Northern Ireland)
Northern Mariana Islands
(Northern Mariana Islands)
Norway
(Norway)
Oman
(Oman)
Pakistan
(Pakistan)
Palau
(Palau)
Palestine
(Palestine)
Panama
(Panama)
Papua New Guinea
(Papua New Guinea)
Paraguay
(Paraguay)
Peru
(Peru)
Philippines
(Philippines)
Pitcairn
(Pitcairn)
Poland
(Poland)
Polynesia, French
(Polynesia, French)
Portugal
(Portugal)
Puerto Rico
(Puerto Rico)
Qatar
(Qatar)
Reunion
(Reunion)
Romania
(Romania)
Russia
(Russia)
Russian Federation
(Russian Federation)
Rwanda
(Rwanda)
S. Georgia and S. Sandwich Isls.
(S. Georgia and S. Sandwich Isls.)
Saint Kitts and Nevis
(Saint Kitts and Nevis)
Saint Lucia
(Saint Lucia)
Saint Vincent and The Grenadines
(Saint Vincent and The Grenadines)
Samoa
(Samoa)
San Marino
(San Marino)
Sao Tome and Principe
(Sao Tome and Principe)
Saudi Arabia
(Saudi Arabia)
Scotland
(Scotland)
Senegal
(Senegal)
Serbia
(Serbia)
Seychelles
(Seychelles)
Sierra Leone
(Sierra Leone)
Singapore
(Singapore)
Slovakia (Slovak Republic)
(Slovakia (Slovak Republic))
Slovenia
(Slovenia)
Solomon Islands
(Solomon Islands)
Somalia
(Somalia)
South Africa
(South Africa)
Southern Territories, French
(Southern Territories, French)
Soviet Union (former)
(Soviet Union (former))
Spain
(Spain)
Sri Lanka
(Sri Lanka)
St. Helena, Ascension and Tristan da
Cunha
(St. Helena, Ascension and Tristan da
Cunha)
St. Pierre and Miquelon
(St. Pierre and Miquelon)
Sudan
(Sudan)
Sudan, South
(Sudan, South)
Suriname
(Suriname)
Svalbard and Jan Mayen Islands
(Svalbard and Jan Mayen Islands)
Swaziland
(Swaziland)
Sweden
(Sweden)
Switzerland
(Switzerland)
Syria
(Syria)
Taiwan
(Taiwan)
Tajikistan
(Tajikistan)
Tanzania
(Tanzania)
Thailand
(Thailand)
Togo
(Togo)
Tokelau
(Tokelau)
Tonga
(Tonga)
Trinidad and Tobago
(Trinidad and Tobago)
Tunisia
(Tunisia)
Turkey
(Turkey)
Turkmenistan
(Turkmenistan)
Turks and Caicos Islands
(Turks and Caicos Islands)
Tuvalu
(Tuvalu)
Uganda
(Uganda)
Ukraine
(Ukraine)
United Arab Emirates
(United Arab Emirates)
United Kingdom (Great Britain)
(United Kingdom (Great Britain))
United States
(United States)
Uruguay
(Uruguay)
US Minor Outlying Islands
(US Minor Outlying Islands)
Uzbekistan
(Uzbekistan)
Vanuatu
(Vanuatu)
Vatican City State (Holy See)
(Vatican City State (Holy See))
Venezuela
(Venezuela)
Viet Nam
(Viet Nam)
Virgin Islands (British)
(Virgin Islands (British))
Virgin Islands (US)
(Virgin Islands (US))
Wales
(Wales)
Wallis and Futuna Islands
(Wallis and Futuna Islands)
Western Sahara
(Western Sahara)
Yemen
(Yemen)
Yugoslavia
(Yugoslavia)
Zaire
(Zaire)
Zambia
(Zambia)
Zimbabwe
(Zimbabwe)

Population: population the individual (or ancestors) belongs to; e.g. white, gypsy, Jewish-Ashkenazi, Africa-N, Sardinia, etc.

Age at death: age at which the individual deceased (when applicable):

35y = 35 years
>43y = still alive at 43y
04y08m = 4 years and 8 months
00y00m01d12h = 1 day and 12 hours
18y? = around 18 years
30y-40y = between 30 and 40 years
>54y = older than 54
? = unknown

VIP: individual/phenotype VIP-status was requested for matchmaking - need collaboration(s) to crack the case - please contact the submitter/curator. NOTE: to get VIP status ask the curator.

Data_av: are additional data available upon request: e.g. pedigree (yes/no/?)

Treatment: treatment of patient

Variants in genes: The individual has variants for this gene.

Panel size: Number of individuals this entry represents; e.g. 1 for an individual, 5 for a family with 5 affected members.

How to query this table

All list views have search fields which can be used to search data. You can search for a complete word or you can search for a part of a search term. If you enclose two or more words in double quotes, LOVD will search for the combination of those words only exactly in the order you specify. Note that search terms are case-insensitive and that wildcards such as * are treated as normal text! For all options, like "and", "or", and "not" searches, or searching for prefixes or suffixes, see the table below.

Operator	Column type	Example	Matches
	Text	Arg	all entries containing 'Arg'
space	Text	Arg Ser	all entries containing 'Arg' and 'Ser'
\|	Text	Arg\|Ser	all entries containing 'Arg' or 'Ser'
!	Text	!fs	all entries not containing 'fs'
^	Text	^p.(Arg	all entries beginning with 'p.(Arg'
$	Text	Ser)$	all entries ending with 'Ser)'
=""	Text	=""	all entries with this field empty
=""	Text	="p.0"	all entries exactly matching 'p.0'
!=""	Text	!=""	all entries with this field not empty
!=""	Text	!="p.0"	all entries not exactly matching 'p.0?'
combination	Text	*\|Ter !fs	all entries containing '*' or 'Ter' but not containing 'fs'
	Date	2020	all entries matching the year 2020
\|	Date	2020-03\|2020-04	all entries matching March or April, 2020
!	Date	!2020-03	all entries not matching March, 2020
<	Date	<2020	all entries before the year 2020
<=	Date	<=2020-06	all entries in or before June, 2020
>	Date	>2020-06	all entries after June, 2020
>=	Date	>=2020-06-15	all entries on or after June 15th, 2020
combination	Date	2019\|2020 <2020-03	all entries in 2019 or 2020, and before March, 2020
	Numeric	23	all entries exactly matching 23
\|	Numeric	23\|24	all entries exactly matching 23 or 24
!	Numeric	!23	all entries not exactly matching 23
<	Numeric	<23	all entries lower than 23
<=	Numeric	<=23	all entries lower than, or equal to, 23
>	Numeric	>23	all entries higher than 23
>=	Numeric	>=23	all entries higher than, or equal to, 23
combination	Numeric	>=20 <30 !23	all entries with values from 20 to 29, but not equal to 23

Some more advanced examples:

Example	Matches
Asian	all entries containing 'Asian', 'asian', including 'Caucasian', 'caucasian', etc.
Asian !Caucasian	all entries containing 'Asian' but not containing 'Caucasian'
Asian\|African !Caucasian	all entries containing 'Asian' or 'African', but not containing 'Caucasian'
"South Asian"	all entries containing 'South Asian', but not containing 'South East Asian'

To sort on a certain column, click on the column header or on the arrows. If that column is already selected to sort on, the sort order will be swapped. The column currently sorted on has a darker blue background color than the other columns. The up and down arrows next to the column name indicate the current sorting direction. When sorting on any field other than the default, LOVD will sort secondarily on the default sort column.

60 entries on 1 page. Showing entries 1 - 60.

Legend

How to query

Individual ID	ID_report	Reference	Remarks	Gender	Consanguinity	Country	Population	Age at death	VIP	Data_av	Treatment	Disease	Phenotype details	Variants	Panel size	Owner
00105073	?	PubMed: Field 2006	-	-	-	-	-	-	-	-	-	?	myelodysplastic syndrome	1	1	Johan den Dunnen
00105074	?	PubMed: Keith 2004	-	-	-	-	-	-	-	-	-	?	paroxysmal nocturnal hemoglobinuria, menorrhagia, anemia, and thrombocytopenia	1	1	Johan den Dunnen
00105075	?	PubMed: Ortmann 2006	-	-	-	-	-	-	-	-	-	?	paroxysmal nocturnal hemoglobinuria, menorrhagia, anemia, and thrombocytopenia	1	1	Johan den Dunnen
00105076	?	PubMed: Du 2009	-	-	-	-	-	-	-	-	-	DKC	dyskeratosis congenita	1	1	Johan den Dunnen
00105077	?	PubMed: Vulliamy 2001	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita	1	1	Johan den Dunnen
00105078	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105079	?	PubMed: Calado 2009	-	-	-	-	-	-	-	-	-	?	pancytopenia	1	1	Johan den Dunnen
00105080	?	PubMed: Vulliamy 2002	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia, myelodysplasia and leukemia	1	1	Johan den Dunnen
00105081	?	PubMed: Marrone 2007	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia, myelodysplasia and leukemia	1	1	Johan den Dunnen
00105082	?	PubMed: Fogarty 2003	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia and thrombocytopenia	1	1	Johan den Dunnen
00105083	?	PubMed: Ortmann 2006	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia and thrombocytopenia	1	1	Johan den Dunnen
00105084	?	PubMed: Ly 2005	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105085	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105086	?	PubMed: Vulliamy 2004	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita and aplastic anemia	1	1	Johan den Dunnen
00105087	?	PubMed: Parry 2011	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita and aplastic anemia	1	1	Johan den Dunnen
00105088	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105089	?	PubMed: Marrone 2007	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105090	?	PubMed: Marrone 2007	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105091	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105092	?	PubMed: Fogarty 2003	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105093	?	PubMed: Ly 2005	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita	1	1	Johan den Dunnen
00105094	?	PubMed: Yamaguchi 2003	-	-	-	-	-	-	-	-	-	Healthy/Control	-	1	1	Johan den Dunnen
00105095	?	PubMed: Marrone 2004	-	-	-	-	-	-	-	-	-	Healthy/Control	-	1	1	Johan den Dunnen
00105096	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	?	hoyeraal hreidarrson syndrome	1	1	Johan den Dunnen
00105097	?	PubMed: Xin 2007	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105098	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	?	myelodysplastic syndrome	1	1	Johan den Dunnen
00105099	?	PubMed: Marrone 2007	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105100	?	PubMed: Yamaguchi 2003	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105101	?	PubMed: Vulliamy 2004	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita	1	1	Johan den Dunnen
00105102	?	PubMed: Yamaguchi 2003	-	-	-	-	-	-	-	-	-	?	myelodysplasia and refractory anemia	1	1	Johan den Dunnen
00105103	?	PubMed: Takeughi 2007	-	-	-	-	-	-	-	-	-	?	myelodysplastic syndrome	1	1	Johan den Dunnen
00105104	?	PubMed: Alder 2008	-	-	-	-	-	-	-	-	-	PFBMFT2	idiopathic pulmonary fibrosis	1	1	Johan den Dunnen
00105105	?	PubMed: Calado 2009	-	-	-	-	-	-	-	-	-	?	pancytopenia	1	1	Johan den Dunnen
00105106	?	PubMed: Du 2009	-	-	-	-	-	-	-	-	-	?	hypoplastic myelodysplastic syndrome	1	1	Johan den Dunnen
00105107	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105108	?	PubMed: Alder 2011	-	-	-	-	-	-	-	-	-	PFBMFT2	idiopathic pulmonary fibrosis	1	1	Johan den Dunnen
00105109	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105110	?	PubMed: Dokal and Vulliamy 2003	-	-	-	-	-	-	-	-	-	DKC	dyskeratosis congenita	1	1	Johan den Dunnen
00105111	?	PubMed: Vulliamy 2001	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita	1	1	Johan den Dunnen
00105112	?	PubMed: Ly 2005	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita, idiopathic pulmonary fibrosis, and dyspnea	1	1	Johan den Dunnen
00105113	?	PubMed: Tsakiri 2007	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita, idiopathic pulmonary fibrosis, and dyspnea	1	1	Johan den Dunnen
00105114	?	PubMed: Ly 2005	-	-	-	-	-	-	-	-	-	?	essential thrombocythemia	1	1	Johan den Dunnen
00105115	?	PubMed: Vulliamy 2001	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita	1	1	Johan den Dunnen
00105116	?	PubMed: Yamaguchi 2003	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105117	?	PubMed: Yamaguchi 2003	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105118	?	PubMed: Vulliamy 2006	-	-	-	-	-	-	-	-	-	DKC	dyskeratosis congenita	1	1	Johan den Dunnen
00105119	?	PubMed: Vulliamy 2006	-	-	-	-	-	-	-	-	-	?	myelodysplasia and dyskeratosis congenita	1	1	Johan den Dunnen
00105120	?	PubMed: Marrone 2007	-	-	-	-	-	-	-	-	-	PFBMFT2	pulmonary fibrosis	1	1	Johan den Dunnen
00105121	?	PubMed: Jongmans 2012	-	-	-	-	-	-	-	-	-	DKC	dyskeratosis congenita	1	1	Johan den Dunnen
00105122	?	PubMed: Vulliamy 2002	-	-	-	-	-	-	-	-	-	Healthy/Control	-	1	1	Johan den Dunnen
00105123	?	PubMed: Yamaguchi 2003	-	-	-	-	-	-	-	-	-	Healthy/Control	-	1	1	Johan den Dunnen
00105124	?	PubMed: Marrone 2004	-	-	-	-	-	-	-	-	-	Healthy/Control	-	1	1	Johan den Dunnen
00105125	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105126	?	PubMed: Vulliamy 2002	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105127	?	PubMed: Vulliamy 2006	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia	1	1	Johan den Dunnen
00105128	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	anemia	aplastic anemia, myelodysplastic syndrome	1	1	Johan den Dunnen
00105129	?	PubMed: Vulliamy 2011	-	-	-	-	-	-	-	-	-	DKC	dyskeratosis congenita	1	1	Johan den Dunnen
00105130	?	PubMed: Vulliamy 2004	-	-	-	-	-	-	-	-	-	DKCA1	autosomal dominant dyskeratosis congenita	1	1	Johan den Dunnen
00105131	?	PubMed: Armanios 2007	-	-	-	-	-	-	-	-	-	PFBMFT2	idiopathic pulmonary fibrosis	1	1	Johan den Dunnen
00433087	Pat63,1	PubMed: Stray-Pedersen 2017	2-generation family, 1 affected, unaffected parents	M	-	Norway	-	-	-	-	-	IMD	neutrophil defect or congenital condition with bone marrow failure such as dyskeratosis congenita and Fanconi-like phenotype, anemia and thrombocytopenia	1	1	Johan den Dunnen

Legend

How to query

Global Variome shared LOVD

TERC (telomerase RNA component)