Full data view for gene NRAS

Information The variants shown are described using the NM_002524.4 transcript reference sequence.

37 entries on 1 page. Showing entries 1 - 37.
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Effect     

Exon     

AscendingDNA change (cDNA)     

ClassClinical     

RNA change     

Protein     

Allele     

DNA change (genomic) (hg19)     

DNA change (hg38)     

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ISCN     

DB-ID     

Variant remarks     

Reference     

ClinVar ID     

dbSNP ID     

Origin     

Segregation     

Frequency     

Re-site     

VIP     

Methylation     

Template     

Technique     

Tissue     

Remarks     

Disease     

ID_report     

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Remarks     

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Data_av     

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Panel size     

Owner     
-?/. - c.-2058A>G likely benign r.(?) p.(=) Unknown g.115261319T>C - CSDE1(NM_001007553.2):c.2264A>G (p.(Asn755Ser), p.(Asn770Ser), p.(Asn801Ser), p.(Asn724Ser)) - CSDE1_000006 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - - - - - - - - - - - - - - - - - - -
+?/. 2 c.34G>A - r.(?) p.(Gly12Ser) Unknown g.115258748C>T g.114716127C>T - - NRAS_000005 - - - - De novo - - - 0 - DNA SEQ - - NS-6 NRAS 1 Altmüller et al, submitted - F ? Germany - - 0 - - 1 Christina Lissewski
+?/. 2 c.34G>C - r.(?) p.(Gly12Arg) Unknown g.115258748C>G g.114716127C>G - - NRAS_000008 - Altmüller et al, submitted - - De novo - - - 0 - DNA SEQ-NG - - NS-6 NRAS 12 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
?/. 2 c.34G>T - r.(?) p.(Gly12Cys) Unknown g.115258748C>A g.114716127C>A - - NRAS_000003 - - - - Somatic - - - 0 - DNA SEQ-NG-I - - leukemia, acute, lymphoblastic, T-cell - - - - - - - - 0 - - 1 Phil Chambers
+?/. - c.35G>A ACMG: 4 r.(?) p.(Gly12Asp) Unknown g.115258747C>T g.114716126C>T - - NRAS_000004 - Trujillano et al., submitted - - De novo - - - 0 - DNA SEQ, SEQ-NG - - RALD;ALPS-4 - Trujillano et al., submitted unaffected non-carrier parents - - - - - 0 - - 1 Daniel Trujillano
+?/. 2 c.35G>A - r.(?) p.(Gly12Asp) Unknown g.115258747C>T g.114716126C>T - - NRAS_000004 - Altmüller et al, submitted - - De novo - - - 0 - DNA SEQ - - NS-6 NRAS 13 Altmüller et al, submitted - M - Germany - - 0 - - 1 Christina Lissewski
+/. - c.35G>C pathogenic r.(?) p.(Gly12Ala) Unknown g.115258747C>G - NRAS(NM_002524.3):c.35G>C (p.G12A) - CSDE1_000005 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - - - - - - - - - - - - - - - - - - -
+?/. 2 c.35G>T - r.(?) p.(Gly12Val) Unknown g.115258747C>A g.114716126C>A - - NRAS_000006 - Altmüller et al, submitted - - De novo - - - 0 - DNA SEQ CVS - NS-6 NRAS 2 Altmüller et al, submitted - M - Germany - - 0 - - 1 Christina Lissewski
+/. - c.35G>T pathogenic r.(?) p.(Gly12Val) Unknown g.115258747C>A - NRAS(NM_002524.3):c.35G>T (p.Gly12Val) - NRAS_000006 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-?/. - c.36T>G likely benign r.(?) p.(=) Unknown g.115258746A>C - NRAS(NM_002524.3):c.36T>G (p.G12=) - NRAS_000018 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
+?/. 2 c.71T>A - r.(?) p.(Ile24Asn) Unknown g.115258711A>T g.114716090A>T - - NRAS_000007 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ - - NS-6 NRAS 3-1 Altmüller et al, submitted - M - Germany - - 0 - - 1 Christina Lissewski
+?/. 2 c.71T>A - r.(?) p.(Ile24Asn) Unknown g.115258711A>T g.114716090A>T - - NRAS_000007 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ - - NS-6 NRAS 3-2 Altmüller et al, submitted - M - Germany - - 0 - - 1 Christina Lissewski
+?/. 2 c.71T>A - r.(?) p.(Ile24Asn) Unknown g.115258711A>T g.114716090A>T - - NRAS_000007 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ - - NS-6 NRAS 3-3 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
+/. - c.71T>A pathogenic r.(?) p.(Ile24Asn) Unknown g.115258711A>T - NRAS(NM_002524.3):c.71T>A (p.Ile24Asn) - NRAS_000007 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-?/. - c.112-8A>G likely benign r.(=) p.(=) Unknown g.115256607T>C - NRAS(NM_002524.3):c.112-8A>G - NRAS_000017 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
+?/. 2i_3 c.112-1_113dup - r.spl p.(Glu37dup) Unknown g.115256598_115256600dup g.114713977_114713979dup 112-1_113dupGGA - NRAS_000009 - Altmüller et al, submitted - - Germline/De novo (untested) - - - 0 - DNA SEQ - - NS-6 NRAS 7 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.149C>T - r.(?) p.(Thr50Ile) Unknown g.115256562G>A g.114713941G>A - - NRAS_000012 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ - - NS-6 NRAS 4-1 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.149C>T - r.(?) p.(Thr50Ile) Unknown g.115256562G>A g.114713941G>A - - NRAS_000012 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ - - NS-6 NRAS 4-2 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.149C>T - r.(?) p.(Thr50Ile) Unknown g.115256562G>A g.114713941G>A - - NRAS_000012 - Altmüller et al, submitted - - Germline ? - - 0 - DNA SEQ - - NS-6 NRAS 9 Altmüller et al, submitted - M - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.149C>T - r.(?) p.(Thr50Ile) Unknown g.115256562G>A g.114713941G>A - - NRAS_000012 - Altmüller et al, submitted - - Germline ? - - 0 - DNA SEQ-NG - - NS-6 NRAS 11 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.173C>T - r.(?) p.(Thr58Ile) Unknown g.115256538G>A g.114713917G>A - - NRAS_000011 - Altmüller et al, submitted - - Germline ? - - 0 - DNA SEQ - - NS-6 NRAS 8 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.179G>A - r.(?) p.(Gly60Glu) Unknown g.115256532C>T g.114713911C>T - - NRAS_000010 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ - - NS-6 NRAS 5-1 Altmüller et al, submitted - M - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.179G>A - r.(?) p.(Gly60Glu) Unknown g.115256532C>T g.114713911C>T - - NRAS_000010 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ - - NS-6 NRAS 5-2 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.179G>A - r.(?) p.(Gly60Glu) Unknown g.115256532C>T g.114713911C>T - - NRAS_000010 - Altmüller et al, submitted - - De novo - - - 0 - DNA SEQ - - NS-6 NRAS 6 Altmüller et al, submitted - F - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.179G>A - r.(?) p.(Gly60Glu) Unknown g.115256532C>T g.114713911C>T - - NRAS_000010 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ-NG - - NS-6 NRAS 10-1 Altmüller et al, submitted - M - Germany - - 0 - - 1 Christina Lissewski
+?/. 3 c.179G>A - r.(?) p.(Gly60Glu) Unknown g.115256532C>T g.114713911C>T - - NRAS_000010 - Altmüller et al, submitted - - Germline yes - - 0 - DNA SEQ-NG - - NS-6 NRAS 10-2 Altmüller et al, submitted - M - Germany - - 0 - - 1 Christina Lissewski
?/. 3 c.181C>A - r.(?) p.(Gln61Lys) Unknown g.115256530G>T g.114713909G>T - - NRAS_000002 - - - - Somatic - - - 0 - DNA SEQ-NG-I - - myeloma, multiple - - B lymphocyte derived from bone marrow removed from patient with multiple myeloma M - - - - 0 - - 1 Phil Chambers
+/. - c.181C>A pathogenic r.(?) p.(Gln61Lys) Unknown g.115256530G>T - NRAS(NM_002524.3):c.181C>A (p.Q61K) - NRAS_000002 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - - - - - - - - - - - - - - - - - - -
+/. - c.182A>G pathogenic r.(?) p.(Gln61Arg) Unknown g.115256529T>C - NRAS(NM_002524.4):c.182A>G (p.(Gln61Arg)) - CSDE1_000004 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - - - - - - - - - - - - - - - - - - - - -
?/. 3 c.182A>T - r.(?) p.(Gln61Leu) Unknown g.115256529T>A g.114713908T>A - - NRAS_000001 - - - - Somatic - - - 0 - DNA SEQ-NG-I - - leukemia, acute, promyelocytic - - - F - - European, white - 0 - - 1 Phil Chambers
-?/. - c.254A>G likely benign r.(?) p.(Asn85Ser) Unknown g.115256457T>C - NRAS(NM_002524.3):c.254A>G (p.Asn85ser) - NRAS_000020 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-?/. - c.322G>A likely benign r.(?) p.(Asp108Asn) Unknown g.115252318C>T - NRAS(NM_002524.4):c.322G>A (p.(Asp108Asn)) - NRAS_000016 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-?/. - c.360G>A likely benign r.(?) p.(=) Unknown g.115252280C>T - NRAS(NM_002524.3):c.360G>A (p.L120=) - NRAS_000015 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-?/. - c.360G>A likely benign r.(?) p.(=) Unknown g.115252280C>T - NRAS(NM_002524.3):c.360G>A (p.L120=) - NRAS_000015 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-?/. - c.384A>G likely benign r.(?) p.(=) Unknown g.115252256T>C - NRAS(NM_002524.3):c.384A>G (p.=) - NRAS_000019 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-?/. - c.450+12C>T likely benign r.(=) p.(=) Unknown g.115252178G>A - NRAS(NM_002524.3):c.450+12C>T - NRAS_000014 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
-?/. - c.*43+20G>A likely benign r.(=) p.(=) Unknown g.115250755C>T - NRAS(NM_002524.3):c.*43+20G>A - NRAS_000013 VKGL data sharing initiative Nederland - - - CLASSIFICATION record - - - 0 - - - - - - - - - - - - - - - - - - -
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